Bee Pollen Granules Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Bee Pollen Granules against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Bee Pollen Granules is a dietary supplement by Beehive Botanicals with 4 active ingredients. Its ingredients are commonly taken for iron-deficiency anemia, low iron stores during pregnancy, fatigue from iron deficiency.Based on those ingredients, 82 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Iron, Bee Pollen. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Bee Pollen Granules by Beehive Botanicals
Ask about any prescription or over-the-counter medication and we check it for interactions with Bee Pollen Granules by Beehive Botanicals — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Bee Pollen Granules by Beehive Botanicals
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Beehive Botanicals Bee Pollen Granules contains 2 active ingredients: iron and bee pollen. Iron is a mineral essential for building red blood cells and preventing anemia.
Bee pollen is a powder made from pollen collected by honeybees, marketed for various health purposes though its effectiveness for most uses isn't well established. The product has no other inactive ingredients listed.
Does it work?
Strong evidence
Iron is well established as effective for treating iron deficiency anemia and anemia of chronic disease, and is commonly used during pregnancy when iron levels drop. It's also possibly effective for heart failure, though the evidence is less robust.
Bee pollen, on the other hand, has insufficient evidence to rate it for most of its marketed uses—including hay fever, amenorrhea, benign prostate enlargement, and hot flashes. One use, athletic performance, is actually rated possibly ineffective.
How safe is it?
Well-documented data
Iron is generally well tolerated at recommended doses, but excess iron can be toxic, so it should only be used when there's a genuine need. The most common side effects from oral iron are gastrointestinal—abdominal pain, constipation, diarrhea, nausea, and vomiting—though serious effects like ulceration are rare.
Iron is considered likely safe in pregnancy (though your prenatal care provider should guide your dose) and likely safe while breastfeeding at appropriate doses. Bee pollen is generally tolerated by many people but can trigger allergic reactions, sometimes severe—especially in those with pollen allergies or allergies to plants in the daisy family (ragweed, chrysanthemums, daisies, marigolds).
Rare serious effects include acute hepatitis, kidney failure, and anaphylaxis. The safety data is insufficient for pregnancy, and bee pollen is best avoided while breastfeeding because safety is unknown.
Meds to double-check
Moderate interaction found
Before taking this product, check your medications against these types: levodopa (Parkinson's disease), quinolone antibiotics (like ciprofloxacin), tetracycline antibiotics, bisphosphonates (osteoporosis), methyldopa (blood pressure), levothyroxine (thyroid), mycophenolate mofetil (immunosuppressant), penicillamine (Wilson's disease), and warfarin (blood thinner). All of these have documented Moderate-severity interactions.
Iron reduces absorption of the first eight; bee pollen may increase bleeding risk with warfarin.
The bottom line
Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product is mainly an iron supplement, which works well for iron deficiency anemia but interacts with numerous medications by reducing their absorption—particularly antibiotics, thyroid hormone, and blood pressure drugs. If you take any prescription medications, run them through the checker on this page before starting.
The bee pollen component adds an allergy risk and has little proven benefit beyond what iron provides.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2013.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Bee Pollen Granules, straight from the product label.
| Brand | Beehive Botanicals |
|---|---|
| Net contents | 16 oz.; 448 grams |
| Market status | On market |
| Date entered into DSLD | Jul 25, 2013 |
| DSLD ID | 24274 |
| Product type | Other Combinations |
| Supplement form | Powder |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Bee Pollen Granules by Beehive Botanicals, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 10 {Calories} | -- |
| Total Carbohydrates | 2 grams | 1% |
| Sugar | 1 Gram(s) | -- |
| Protein | 1 Gram(s) | 1% |
| Iron | 4 mg | 22% |
| Bee Pollen | 2.94 grams | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
BEEHIVE BOTANICALS, THE OLDEST AND LARGEST PRODUCER OF BEE PROPOLIS IN THE USA, IS KNOWN WORLD WIDE FOR HIGH QUALITY BEE PRODUCTS. OUR DOMESTIC BEE POLLEN IS 100% PURE AND AND NATURAL, CAREFULLY PREPARED FOR YOUR GOOD HEALTH.
NOTE: NATURAL INGREDIENTS MAY EXHIBIT VARIATION IN COLOR, TASTE AND ODOR FROM HARVEST TO HARVEST.
Suggested/Recommended/Usage/Directions
SUGGESTED USE: AS A DIETARY SUPPLEMENT TAKE ONE TO TWO TEASPOONS DAILY.
Precautions
PLEASE USE CAUTION WHEN TAKING BEE POLLEN FOR THE FIRST TIME - SOME PEOPLE CAN HAVE AN ALLERGIC REACTION, GRADUALLY INCREASE FROM ONE TO TWO TEASPOONS DAILY.
CAUTION: BEE PRODUCTS MAY CAUSE ALLERGIC REACTION IN ALLERGY SUFFERERS.
FDA Disclaimer Statement
DIETARY SUPPLEMENT
Storage
PLEASE REFRIGERATE
General
VER 8801-3
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Bee Pollen Granules by Beehive Botanicals label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Bee Pollen Granules by Beehive Botanicals
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 tsp Dosage formPowder Servings per container152 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Sugar
Protein
Iron
Interacts with80 drugs
Iron is an essential mineral your body needs to make hemoglobin and carry oxygen in the blood. Supplements are mainly useful for treating or preventin...
Iron monograph & interactionsBee Pollen
Interacts with2 drugs
Bee pollen is a nutrient-rich product collected by bees and marketed as a 'superfood' for energy and immune support, but solid human evidence for most...
Bee Pollen monograph & interactionsBee Pollen Granules by Beehive Botanicals Drug Interactions
HelloPharmacist Interaction Report
Beehive Botanicals Bee Pollen Granules contains two active ingredients, and together they interact with a significant number of medications.
Iron, the first ingredient, is responsible for the most serious documented interactions—a series of Moderate-severity effects where iron reduces how your body absorbs certain drugs, potentially making them less effective. These affected medications include levodopa (used for Parkinson's disease), quinolone and tetracycline antibiotics, bisphosphonates (for bone health), methyldopa (a blood pressure drug), levothyroxine (thyroid hormone), mycophenolate mofetil (an immunosuppressant), and penicillamine (for Wilson's disease).
The second ingredient, bee pollen, has one documented Moderate-severity interaction: it may increase bleeding risk in people taking warfarin (a blood thinner).
Read the full breakdown — every affected drug type, severity by severity
Additionally, to keep things clear: iron's interactions all work the same way—it binds to these medications in your stomach and prevents your body from absorbing them properly. Iron should be separated from these drugs by at least 2 hours (or longer for some, like tetracycline antibiotics, which need 4 hours after iron).
The bee pollen interaction with warfarin is less common but worth knowing about if you take that medication.
Altogether, these interactions span 81 individual medications. Neither iron nor bee pollen have been checked for interactions with all other drugs, so this list isn't exhaustive.
Use the medication checker below with your exact prescription and over-the-counter medications before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Bee Pollen Granules?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Bee Pollen Granules interact with 82 drugs. Click any drug to see the details.
2 of the 4 ingredients in Bee Pollen Granules interact with drugs. Each result below shows which ingredient is responsible. Iron Bee Pollen
Emtricitabine, Tenofovir Alafenamide FumarateDescovy
How Emtricitabine, Tenofovir Alafenamide Fumarate interacts with Bee Pollen Granules — through 1 ingredient. Tap an ingredient for the detail:
IronBictegravir/emtricitabine/tenofovir Alafenamide (biktarvy) Moderate
Interaction Summary
Iron might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption when taken in a fasting state.
Read the full Iron + Emtricitabine, Tenofovir Alafenamide Fumarate interactionEnoxacinPenetrex
How Enoxacin interacts with Bee Pollen Granules — through 1 ingredient. Tap an ingredient for the detail:
IronQuinolone Antibiotics Moderate
Interaction Summary
Iron might decrease levels of quinolone antibiotics by reducing their absorption.
Read the full Iron + Enoxacin interactionEravacyclineXerava
How Eravacycline interacts with Bee Pollen Granules — through 1 ingredient. Tap an ingredient for the detail:
IronTetracycline Antibiotics Moderate
Interaction Summary
Iron might decrease levels of tetracycline antibiotics by reducing their absorption.
Read the full Iron + Eravacycline interactionEtidronate DisodiumDidrocal, Didronel
How Etidronate Disodium interacts with Bee Pollen Granules — through 1 ingredient. Tap an ingredient for the detail:
IronBisphosphonates Moderate
Interaction Summary
Iron reduces the absorption of bisphosphonates.
Read the full Iron + Etidronate Disodium interactionFinafloxacinXtoro
How Finafloxacin interacts with Bee Pollen Granules — through 1 ingredient. Tap an ingredient for the detail:
IronQuinolone Antibiotics Moderate
Interaction Summary
Iron might decrease levels of quinolone antibiotics by reducing their absorption.
Read the full Iron + Finafloxacin interactionGatifloxacinTequin, Tequin Injection
How Gatifloxacin interacts with Bee Pollen Granules — through 1 ingredient. Tap an ingredient for the detail:
IronQuinolone Antibiotics Moderate
Interaction Summary
Iron might decrease levels of quinolone antibiotics by reducing their absorption.
Read the full Iron + Gatifloxacin interactionGemifloxacinFactive
How Gemifloxacin interacts with Bee Pollen Granules — through 1 ingredient. Tap an ingredient for the detail:
IronQuinolone Antibiotics Moderate
Interaction Summary
Iron might decrease levels of quinolone antibiotics by reducing their absorption.
Read the full Iron + Gemifloxacin interactionGrepafloxacinRaxar
How Grepafloxacin interacts with Bee Pollen Granules — through 1 ingredient. Tap an ingredient for the detail:
IronQuinolone Antibiotics Moderate
Interaction Summary
Iron might decrease levels of quinolone antibiotics by reducing their absorption.
Read the full Iron + Grepafloxacin interactionHydrochlorothiazide, MethyldopaAldoril 15, Aldoril 25, Aldoril D30, Methazide
How Hydrochlorothiazide, Methyldopa interacts with Bee Pollen Granules — through 1 ingredient. Tap an ingredient for the detail:
IronMethyldopa (aldomet) Moderate
Interaction Summary
Iron might decrease methyldopa levels by reducing its absorption.
Read the full Iron + Hydrochlorothiazide, Methyldopa interactionIbandronateBoniva, Boniva IV
How Ibandronate interacts with Bee Pollen Granules — through 1 ingredient. Tap an ingredient for the detail:
IronBisphosphonates Moderate
Interaction Summary
Iron reduces the absorption of bisphosphonates.
Read the full Iron + Ibandronate interactionLamivudine, RaltegravirDutrebis
How Lamivudine, Raltegravir interacts with Bee Pollen Granules — through 1 ingredient. Tap an ingredient for the detail:
IronIntegrase Inhibitors Moderate
Interaction Summary
Theoretically, taking iron along with integrase inhibitors might decrease the levels and clinical effects of these drugs.
Read the full Iron + Lamivudine, Raltegravir interactionLamivudine, Tenofovir Disoproxil FumarateTemixys
How Lamivudine, Tenofovir Disoproxil Fumarate interacts with Bee Pollen Granules — through 1 ingredient. Tap an ingredient for the detail:
IronBictegravir/emtricitabine/tenofovir Alafenamide (biktarvy) Moderate
Interaction Summary
Iron might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption when taken in a fasting state.
Read the full Iron + Lamivudine, Tenofovir Disoproxil Fumarate interactionLevodopaInbrija, Larodopa
How Levodopa interacts with Bee Pollen Granules — through 1 ingredient. Tap an ingredient for the detail:
IronLevodopa Moderate
Interaction Summary
Iron might decrease levodopa levels by reducing its absorption.
Read the full Iron + Levodopa interactionLevodopa, CarbidopaDuodopa
How Levodopa, Carbidopa interacts with Bee Pollen Granules — through 1 ingredient. Tap an ingredient for the detail:
IronLevodopa Moderate
Interaction Summary
Iron might decrease levodopa levels by reducing its absorption.
Read the full Iron + Levodopa, Carbidopa interactionLevofloxacinLeva-pak, Levaquin, Levaquin Injection
How Levofloxacin interacts with Bee Pollen Granules — through 1 ingredient. Tap an ingredient for the detail:
IronQuinolone Antibiotics Moderate
Interaction Summary
Iron might decrease levels of quinolone antibiotics by reducing their absorption.
Read the full Iron + Levofloxacin interactionLevofloxacin (ophthalmic)Levofloxacin
How Levofloxacin (ophthalmic) interacts with Bee Pollen Granules — through 1 ingredient. Tap an ingredient for the detail:
IronQuinolone Antibiotics Moderate
Interaction Summary
Iron might decrease levels of quinolone antibiotics by reducing their absorption.
Read the full Iron + Levofloxacin (ophthalmic) interactionLevothyroxineEltroxin, Estre, Euthyrox, Levo-T, Levolet, Levothroid +5 more
How Levothyroxine interacts with Bee Pollen Granules — through 1 ingredient. Tap an ingredient for the detail:
IronLevothyroxine (synthroid, Others) Moderate
Interaction Summary
Iron might decrease levothyroxine levels by reducing its absorption.
Read the full Iron + Levothyroxine interactionLevothyroxine SodiumErmez, Thyquidity, Tirosint-Sol
How Levothyroxine Sodium interacts with Bee Pollen Granules — through 1 ingredient. Tap an ingredient for the detail:
IronLevothyroxine (synthroid, Others) Moderate
Interaction Summary
Iron might decrease levothyroxine levels by reducing its absorption.
Read the full Iron + Levothyroxine Sodium interactionLevothyroxine, LiothyronineArmour Thyroid
How Levothyroxine, Liothyronine interacts with Bee Pollen Granules — through 1 ingredient. Tap an ingredient for the detail:
IronLevothyroxine (synthroid, Others) Moderate
Interaction Summary
Iron might decrease levothyroxine levels by reducing its absorption.
Read the full Iron + Levothyroxine, Liothyronine interactionLomefloxacinMaxaquin
How Lomefloxacin interacts with Bee Pollen Granules — through 1 ingredient. Tap an ingredient for the detail:
IronQuinolone Antibiotics Moderate
Interaction Summary
Iron might decrease levels of quinolone antibiotics by reducing their absorption.
Read the full Iron + Lomefloxacin interactionMethyldopaAldomet, Methyldopa
How Methyldopa interacts with Bee Pollen Granules — through 1 ingredient. Tap an ingredient for the detail:
IronMethyldopa (aldomet) Moderate
Interaction Summary
Iron might decrease methyldopa levels by reducing its absorption.
Read the full Iron + Methyldopa interactionMetronidazole, Tetracyline, Bismuth Subcitrate PotassiumPylera
How Metronidazole, Tetracyline, Bismuth Subcitrate Potassium interacts with Bee Pollen Granules — through 1 ingredient. Tap an ingredient for the detail:
IronTetracycline Antibiotics Moderate
Interaction Summary
Iron might decrease levels of tetracycline antibiotics by reducing their absorption.
Read the full Iron + Metronidazole, Tetracyline, Bismuth Subcitrate Potassium interactionMinocyclineAcnamino MR, Aknemin, Amzeeq, Arestin Miscrosperes, Dynacin, Minocin +6 more
How Minocycline interacts with Bee Pollen Granules — through 1 ingredient. Tap an ingredient for the detail:
IronTetracycline Antibiotics Moderate
Interaction Summary
Iron might decrease levels of tetracycline antibiotics by reducing their absorption.
Read the full Iron + Minocycline interactionMinocycline HydrochlorideMinolira, Ximino
How Minocycline Hydrochloride interacts with Bee Pollen Granules — through 1 ingredient. Tap an ingredient for the detail:
IronTetracycline Antibiotics Moderate
Interaction Summary
Iron might decrease levels of tetracycline antibiotics by reducing their absorption.
Read the full Iron + Minocycline Hydrochloride interactionMoxifloxacinAvelox
How Moxifloxacin interacts with Bee Pollen Granules — through 1 ingredient. Tap an ingredient for the detail:
IronQuinolone Antibiotics Moderate
Interaction Summary
Iron might decrease levels of quinolone antibiotics by reducing their absorption.
Read the full Iron + Moxifloxacin interactionMycophenolate MofetilCellCept
How Mycophenolate Mofetil interacts with Bee Pollen Granules — through 1 ingredient. Tap an ingredient for the detail:
IronMycophenolate Mofetil (cellcept) Moderate
Interaction Summary
Theoretically, iron might decrease mycophenolate mofetil levels by reducing its absorption.
Read the full Iron + Mycophenolate Mofetil interactionNalidixic AcidNegGram
How Nalidixic Acid interacts with Bee Pollen Granules — through 1 ingredient. Tap an ingredient for the detail:
IronQuinolone Antibiotics Moderate
Interaction Summary
Iron might decrease levels of quinolone antibiotics by reducing their absorption.
Read the full Iron + Nalidixic Acid interactionNorfloxacinNorflox, Noroxin
How Norfloxacin interacts with Bee Pollen Granules — through 1 ingredient. Tap an ingredient for the detail:
IronQuinolone Antibiotics Moderate
Interaction Summary
Iron might decrease levels of quinolone antibiotics by reducing their absorption.
Read the full Iron + Norfloxacin interactionOfloxacinFloxin, Floxin Injection, Floxin Otic, Oflox
How Ofloxacin interacts with Bee Pollen Granules — through 1 ingredient. Tap an ingredient for the detail:
IronQuinolone Antibiotics Moderate
Interaction Summary
Iron might decrease levels of quinolone antibiotics by reducing their absorption.
Read the full Iron + Ofloxacin interactionOmadacycline (iv)Nuzyra
How Omadacycline (iv) interacts with Bee Pollen Granules — through 1 ingredient. Tap an ingredient for the detail:
IronTetracycline Antibiotics Moderate
Interaction Summary
Iron might decrease levels of tetracycline antibiotics by reducing their absorption.
Read the full Iron + Omadacycline (iv) interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Bee Pollen Granules with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Iron
Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy)
Iron might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption when taken in a fasting state.
Advise patients that bictegravir/emtricitabine/tenofovir alafenamide and iron can be taken together if taken with food. However, if taken on an empty stomach, bictegravir/emtricitabine/tenofovir alafenamide should not be taken with, or 2 hours after, iron containing products.
Bisphosphonates
Iron reduces the absorption of bisphosphonates.
Advise patients that doses of bisphosphonates should be separated by at least two hours from doses of all other medications, including supplements such as iron. Divalent cations, including iron, can decrease absorption of bisphosphonates by forming insoluble complexes in the gastrointestinal tract.
Denosumab (Prolia, Others)
Administration of intravenous iron within one month of denosumab administration might increase the risk of severe hypophosphatemia and hypocalcemia.
A case of severe hypocalcemia (albumin corrected calcium 6.88 mg/dL, ionized calcium 3.68 mg/dL) and hypophosphatemia (<0.5 mg/dL) with respiratory acidosis, QT interval prolongation, and nonsustained ventricular tachycardia was reported in a 76-year-old male who had received an iron polymaltose infusion within 2 weeks of a subcutaneous injection of denosumab. Serum parathyroid hormone was also elevated (348 pg/mL). Subsequent iron infusions with iron polymaltose and ferric carboxymaltose were followed by transient hypophosphatemia, but without hypocalcemia. Additionally, a literature review describes 6 additional cases of hypophosphatemia and hypocalcemia in patients 52-92 years of age who had been administered intravenous iron as either ferric carboxymaltose or iron polymaltose and subcutaneous denosumab within 1-4 weeks of each other.
Dolutegravir (Tivicay)
Iron might decrease dolutegravir levels by reducing its absorption.
Advise patients to take dolutegravir at least 2 hours before or 6 hours after taking iron. Pharmacokinetic research shows that iron can decrease the absorption of dolutegravir from the gastrointestinal tract through chelation. When taken under fasting conditions, a single dose of ferrous fumarate 324 mg orally along with dolutegravir 50 mg reduces overall exposure to dolutegravir by 54%.
Integrase Inhibitors
Theoretically, taking iron along with integrase inhibitors might decrease the levels and clinical effects of these drugs.
Iron is a divalent cation. There is concern that iron may decrease the absorption of integrase inhibitors from the gastrointestinal tract through chelation. One pharmacokinetic study shows that iron can decrease blood levels of the specific integrase inhibitor dolutegravir through chelation. Also, other pharmacokinetic research shows that other divalent cations such as calcium can decrease the absorption and levels of some integrase inhibitors through chelation.
Levodopa
Iron might decrease levodopa levels by reducing its absorption.
Advise patients to separate doses of levodopa and iron as much as possible. There is some evidence in healthy people that iron forms chelates with levodopa, reducing the amount of levodopa absorbed by around 50%. The clinical significance of this hasn't been determined.
Levothyroxine (Synthroid, Others)
Iron might decrease levothyroxine levels by reducing its absorption.
Advise patients to separate levothyroxine and iron doses by at least 2 hours. Iron can decrease the absorption and efficacy of levothyroxine by forming insoluble complexes in the gastrointestinal tract.
Methyldopa (Aldomet)
Iron might decrease methyldopa levels by reducing its absorption.
Advise patients to separate methyldopa and iron doses by at least 2 hours. Iron can decrease the absorption of methyldopa from the gastrointestinal tract through chelation, resulting in increases in blood pressure.
Mycophenolate Mofetil (Cellcept)
Theoretically, iron might decrease mycophenolate mofetil levels by reducing its absorption.
Advise patients to take iron 4-6 hours before, or 2 hours after, mycophenolate mofetil. It has been suggested that a decrease of absorption is possible, probably by forming nonabsorbable chelates. However, mycophenolate pharmacokinetics are not affected by iron supplementation in available clinical research.
Penicillamine (Cuprimine, Depen)
Iron might decrease penicillamine levels by reducing its absorption.
Advise patients to separate penicillamine and iron doses by at least 2 hours. Oral iron supplements can reduce absorption of penicillamine by 30% to 70%, probably due to chelate formation. In people with Wilson's disease, this interaction has led to reduced efficacy of penicillamine.
Quinolone Antibiotics
Iron might decrease levels of quinolone antibiotics by reducing their absorption.
Advise patients to separate quinolone antibiotics and iron doses by at least 2 hours. Iron decreases the absorption of quinolones due to formation of insoluble complexes in the gastrointestinal tract.
Tetracycline Antibiotics
Iron might decrease levels of tetracycline antibiotics by reducing their absorption.
Advise patients to take iron at least 2 hours before or 4 hours after tetracycline antibiotics. Concomitant use can decrease absorption of tetracycline antibiotics from the gastrointestinal tract by 50% to 90%.
Chloramphenicol
Theoretically, taking chloramphenicol with iron might reduce the response to iron therapy in iron deficiency anemia.
Chloramphenicol interferes with erythrocyte maturation. However, since chloramphenicol isn't usually taken for prolonged periods, this isn't likely to be clinically significant.
Bee Pollen
Warfarin (Coumadin)
There is some concern that bee pollen might interact with warfarin and increase the risk of bleeding.
In one case report, a patient on warfarin had a stable international normalized ratio (INR) of 1.9-3.3 for 9 months. The patient's INR was found to be 7.1 after starting bee pollen granules one teaspoon twice daily for approximately one month. The patient's warfarin dose was decreased by approximately 11% in order to return the INR to the therapeutic range while continuing the bee pollen supplement.
Brand information
Manufacturer and brand details for Bee Pollen Granules, from the product label.
Beehive Botanicals
See all Beehive Botanicals products- Name
- BEEHIVE BOTANICALS, INC
- Street Address
- 16297 WEST NURSERY ROAD
- City
- HAYWARD
- State
- WI
- ZipCode
- 54843
- Phone Number
- 715-634-4274
Bee Pollen Granules by Beehive Botanicals: Common Questions
Does Bee Pollen Granules by Beehive Botanicals interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What is bee pollen and what does it do?
Can I take this while pregnant or breastfeeding?
What are the common side effects of iron?
Could I have an allergic reaction to bee pollen?
Why does iron need to be separated from my medications?
Is this product safe if I use it long-term without checking my iron levels?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Bee Pollen Granules is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Bee Pollen Granules’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Iron
Interacts with 80 drugsIron is an essential mineral your body needs to make hemoglobin and carry oxygen in the blood. Supplements are mainly useful for treating or preventing iron deficiency and iron-deficiency an...
Read the full Iron monograph → Herb & supplement monographBee Pollen
Interacts with 2 drugsBee pollen is a nutrient-rich product collected by bees and marketed as a 'superfood' for energy and immune support, but solid human evidence for most of these claims is lacking. It can caus...
Read the full Bee Pollen monograph →Sources & How We Checked
Bee Pollen Granules's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 87 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Iron 72 references
- McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
- Bruner AB, Joffe A, Duggan AK, et al. Randomized study of cognitive effects of iron supplementation in non- anaemic iron-deficient adolescent girls. Lancet 1996;348:992-6.
- Ullen H, Augustsson K, Gustavsson C, Steineck G. Supplementary iron intake and risk of cancer: reversed causality? Cancer Lett 1997;114:215-6.
- Reunanen A, Takkunen H, Knekt P, et al. Body iron stores, dietary iron intake and coronary heart disease mortality. J Intern Med 1995;238:223-30. PubMed
- Lund EK, Wharf SG, Fairweather-Tait SJ, Johnson IT. Oral ferrous sulfate supplements increase the free radical-generating capacity of feces from healthy volunteers. Am J Clin Nutr 1999;69:250-5.
- Rehman A, Collis CS, Yang M, et al. The effects of iron and vitamin C co-supplementation on oxidative damage to DNA in healthy volunteers. Biochem Biophys Res Comm 1998;246:293-8. PubMed
- Klipstein-Grobusch K, Grobbee DE, den Breeijen JH, et al. Dietary iron and risk of myocardial infarction in the Rotterdam Study. Am J Epidemiol 1999;149:421-8. PubMed
- Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
- Tatro DS, ed. Drug Interactions Facts. Facts and Comparisons Inc., St. Louis, MO. 1999.
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
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