Interactions on record — worth a quick check against your medications. Based on 5 of 8 ingredients. Check your meds →
Dietary supplement

Bifidus Power Blend Ingredients & Drug Interactions

by Body Ecology

Bifidus Power Blend label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Bifidus Power Blend against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Bifidus Power Blend is a dietary supplement by Body Ecology with 8 active ingredients. Its ingredients are commonly taken for digestive health and regularity, irritable bowel syndrome (ibs), diarrhea (including antibiotic-related).Based on those ingredients, 308 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are B. longum, B. bifidum, B. breve. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Bifidus Power Blend by Body Ecology

Ask about any prescription or over-the-counter medication and we check it for interactions with Bifidus Power Blend by Body Ecology — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Bifidus Power Blend by Body Ecology

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 8 active ingredients.
  • “B. bifidum / B. lactis” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.

Bifidus Power Blend contains eight active ingredients: four Bifidobacterium species (B. bifidum, B. longum, B. breve, and B. infantis), one Lactobacillus species (L. salivarius), one Saccharomyces yeast strain (S. boulardii), and B. lactis. Together, these are live probiotic organisms meant to support digestive and immune health.

The blend also includes inulin (sold as Frutafit), a prebiotic fiber that feeds beneficial bacteria in your gut. The inactive ingredients consist of a vegetarian capsule as the delivery form.

There are no other fillers or binders listed.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: probiotic support for digestive and immune health.
  • We looked for evidence on: Abdominal pain, Antibiotic-associated diarrhea, Clostridioides difficile infection, Colic, Constipation, Crohn disease — and 4 related terms.
  • The strongest evidence on file: Saccharomyces Boulardii is rated "Possibly Effective" for Antibiotic-associated diarrhea (Natural Medicines).
  • Also on file: Saccharomyces Boulardii is rated "Possibly Effective" for Rotaviral diarrhea, Travelers' diarrhea, Clostridioides difficile infection.
  • Also on file: Inulin is rated "Possibly Effective" for Constipation.

Evidence is mixed across the ingredients. Saccharomyces boulardii is possibly effective for several types of diarrhea — rotaviral, traveler's, antibiotic-associated — as well as for Clostridioides difficile infection (a serious bacterial infection), necrotizing enterocolitis in newborns, and H. pylori infection.

B. bifidum and inulin are both possibly effective for irritable bowel syndrome. B. bifidum is also possibly effective for respiratory tract infections.

Inulin is possibly effective for obesity and constipation, and possibly effective for diabetes. However, for many other proposed uses — including anxiety, cognitive decline, asthma, allergic rhinitis, and several others — the evidence we hold is insufficient to draw firm conclusions.

B. breve is rated possibly ineffective for age-related cognitive decline and sepsis. Talk with your doctor about what outcome you're hoping for; that'll help determine whether this blend is a reasonable fit for your situation.

The evidence, ingredient by ingredient Bifidobacterium Longum Bifidobacterium Bifidum Bifidobacterium Breve Saccharomyces Boulardii Inulin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

These probiotics are generally well tolerated in healthy people. That said, if your immune system is weakened or you're seriously ill — especially if you're in the hospital on multiple medications — you should check with your doctor before use.

There are rare documented cases of infections caused by these organisms in critically ill patients, though such cases are uncommon. Common side effects are mild and gastrointestinal: bloating, flatulence, gas, and stomach cramps, especially when you first start or at higher doses.

Very rarely, individuals have reported vomiting, nausea, or a dry cough. Inulin in particular often causes gas and bloating at higher doses.

One rare but serious side effect reported for inulin is anaphylaxis (a severe allergic reaction), though this is very uncommon. Pregnancy and lactation safety data are limited — B. bifidum and B. longum are rated possibly safe during pregnancy, but data for the other ingredients are not on file.

Talk with your doctor or pharmacist if you're pregnant or breastfeeding.

Side effects, ingredient by ingredient Bifidobacterium Longum Bifidobacterium Bifidum Bifidobacterium Breve Saccharomyces Boulardii Inulin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 5 of the 5 matched ingredients can interact with medications — Saccharomyces Boulardii, Inulin, Bifidobacterium Breve, Bifidobacterium Bifidum, Bifidobacterium Longum.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 308 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this, check whether you're on any antibiotic drugs — these can reduce the effectiveness of the probiotic organisms in the blend. If you use antifungal medications (Minor concern) or diabetes medications (Minor concern), mention those too.

Your pharmacist can help you time the doses to minimize any effect.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Bifidus Power Blend may be worth considering if you're dealing with irritable bowel syndrome, diarrhea, or constipation and want to try probiotics. If you take antibiotics or antifungal medications, or if you manage diabetes with medication, check your specific drugs with the tool on this page before starting — timing and interactions matter.

People who are critically ill or have weakened immune systems should talk with their doctor first. Any new side effects or concerns: let your pharmacist know.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 8 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 25, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Bifidus Power Blend, straight from the product label.

Brand Body Ecology
Barcode (UPC) 758000300155
Net contents 90 Vegetarian Capsules
Market status On market
Date entered into DSLD Oct 25, 2018
DSLD ID 181119
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Bifidus Power Blend by Body Ecology, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
90
UPC/BARCODE
758000300155
IngredientAmount% DV
B. lactis0 NP--
B. bifidum0 NP--
B. longum0 NP--
B. bifidum / B. lactis0 NP--
B. breve0 NP--
L. salivarius0 NP--
B. infantis0 NP--
Saccharomyces boulardii0 NP--
Frutafit368.8 mg--

Other ingredients: Vegetarian Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Full Spectrum Bifidus Formula Enhanced with L. Salivarius and S. Boulardii

Brand IP Statement(s)

Body Ecology Bifidus Power blend contains the most abundant probiotic strains of beneficial bacteria present in the large intestine of a healthy newborn, breast-fed baby.

General Statements

Research shows that Bifidus strains may help reduce anxiety, improve constipation, support immunity, degrade oxalates, and reduce inflammation.

20 billion microbiota per capsule. Gently relieves constipation & diarrhea Helps reduce levels of candida

Suggested/Recommended/Usage/Directions

Recommended usage: Take 3 capsules per day with or without meals, or as recommended by your health care professional.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug administration. this product is not intended to diagnose, treat, cure, or prevent disease.

General

BE022 K16

FDA Statement of Identity

Dietary Supplement

Formulation

Gluten free

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Bifidus Power Blend by Body Ecology label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Bifidus Power Blend label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Bifidus Power Blend by Body Ecology

These are the 8 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

B. longum

Interacts with
182 drugs
0 NP per serving

Bifidobacterium longum is a 'friendly' bacterium found naturally in the human gut and used as a probiotic. It is generally well tolerated and is most...

B. longum monograph & interactions

B. bifidum / B. lactis

0 NP per serving

B. breve

Interacts with
182 drugs
0 NP per serving

Bifidobacterium breve is a 'friendly' gut bacterium taken as a probiotic, most often to support digestion and balance the gut microbiome. Some studies...

B. breve monograph & interactions

L. salivarius

0 NP per serving

B. infantis

0 NP per serving

Saccharomyces boulardii

Interacts with
40 drugs
0 NP per serving

Saccharomyces boulardii is a beneficial yeast used as a probiotic, with the strongest evidence for preventing and treating certain types of diarrhea,...

Saccharomyces boulardii monograph & interactions

Frutafit

Interacts with
86 drugs
368.8 mg per serving

Inulin is a type of plant fiber (a prebiotic) found naturally in foods like chicory root, onions, and garlic, and it is widely added to supplements an...

Frutafit monograph & interactions

Other (inactive) ingredients: Vegetarian Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Bifidus Power Blend by Body Ecology Drug Interactions

Want to check YOUR meds against Bifidus Power Blend?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
308Drugs
182 Moderate 126 Minor

Ingredients driving the most interactions

B. longum 182
B. bifidum 182
B. breve 182
Frutafit 86
Saccharomyces boulardii 40

Individual Drug Interactions

The ingredients in Bifidus Power Blend interact with 308 drugs. Click any drug to see the details.

5 of the 8 ingredients in Bifidus Power Blend interact with drugs. Each result below shows which ingredient is responsible. B. longum B. bifidum B. breve Frutafit Saccharomyces boulardii

Each ingredient & the kinds of drugs it affects

For each ingredient in Bifidus Power Blend with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

B. longum1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B. longum.
Since B. longum preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. longum preparations by at least 2 hours.

Likelihood Probable Evidence D
B. longum full monograph & interactions

B. bifidum1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Bifidobacterium. bifidum with antibiotic drugs might decrease the effectiveness of B. bifidum.
Since B. bifidum preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. bifidum preparations by at least 2 hours.

Likelihood Probable Evidence D
B. bifidum full monograph & interactions

B. breve1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B. breve.
Since B. breve preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. breve preparations by at least 2 hours.

Likelihood Probable Evidence D
B. breve full monograph & interactions

Frutafit1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, inulin might increase the risk of hypoglycemia with antidiabetes drugs.
Some clinical research shows that inulin improves glycemic control in patients with diabetes; however, it is unclear if it has hypoglycemic effects.

Likelihood Unlikely Evidence D
Frutafit full monograph & interactions

Saccharomyces boulardii1 drug type · 40 drugs

Antifungals

Theoretically, taking antifungals with Saccharomyces boulardii might decrease the effectiveness of Saccharomyces boulardii.
S. boulardii is a live yeast. Therefore, simultaneously taking antifungals might kill a significant number of the organisms.

Likelihood Possible Evidence D
Saccharomyces boulardii full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Bifidus Power Blend, from the product label.

Body Ecology

See all Body Ecology products
Name
Body Ecology
City
Los Angeles
State
CA
ZipCode
90036
Phone Number
800-511-2660
Pharmacist Counseling Corner

Bifidus Power Blend by Body Ecology: Common Questions

Does Bifidus Power Blend by Body Ecology interact with any medications?
Yes. Based on its ingredients, Bifidus Power Blend has a known interaction with 308 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Bifidus Power Blend contains 8 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is Saccharomyces boulardii, and why is it in a probiotic blend?
It's a live yeast, not a bacterium, but it works alongside the bacterial probiotics to support digestive health. It's possibly effective for several types of diarrhea and for fighting H. pylori and C. difficile infections — conditions the bacterial strains alone may not cover as well.
Will this help my irritable bowel syndrome?
B. bifidum and inulin are both possibly effective for IBS, so this blend has some ingredients with evidence behind them for that use. That doesn't guarantee it'll work for you personally — talk with your doctor about whether to try it and how long to give it.
Can I take this if I'm on antibiotics?
You can, but you'll need to separate the doses. Since antibiotics kill live organisms, take your antibiotic at one time of day and this supplement several hours apart — your pharmacist can help you schedule it. The timing matters so the antibiotic doesn't wipe out the probiotics.
What are the most common side effects?
Bloating, flatulence, gas, and mild stomach cramps, especially at the start or at higher doses. These usually settle down. Very rarely, people have reported nausea, vomiting, or a cough — if anything unusual happens, stop and call your pharmacist.
Is it safe to take while breastfeeding?
Safety data for most of these ingredients while breastfeeding aren't on file. B. longum and B. longum are rated possibly safe during pregnancy and lactation, but for the others we don't have enough information. Talk with your doctor or pharmacist for advice specific to your situation.
How does the inulin in this product work?
Inulin is a prebiotic fiber — it feeds the beneficial bacteria already in your gut, helping them grow. It's possibly effective for constipation, obesity, and diabetes. It often causes gas and bloating, especially at higher doses, so start low if your stomach is sensitive.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Bifidus Power Blend is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Bifidus Power Blend label
Go deeper

The Full Monographs Behind Bifidus Power Blend’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Bifidobacterium Longum

Interacts with 182 drugs

Bifidobacterium longum is a 'friendly' bacterium found naturally in the human gut and used as a probiotic. It is generally well tolerated and is most studied for digestive issues, though evi...

Read the full Bifidobacterium Longum monograph → Herb & supplement monograph

Bifidobacterium Bifidum

Interacts with 182 drugs

Bifidobacterium bifidum is a 'friendly' bacteria (probiotic) that naturally lives in the human gut and is taken to support digestion and gut balance. Some evidence suggests probiotics may he...

Read the full Bifidobacterium Bifidum monograph → Herb & supplement monograph

Bifidobacterium Breve

Interacts with 182 drugs

Bifidobacterium breve is a 'friendly' gut bacterium taken as a probiotic, most often to support digestion and balance the gut microbiome. Some studies suggest possible benefits for certain d...

Read the full Bifidobacterium Breve monograph → Herb & supplement monograph

Saccharomyces Boulardii

Interacts with 40 drugs

Saccharomyces boulardii is a beneficial yeast used as a probiotic, with the strongest evidence for preventing and treating certain types of diarrhea, including antibiotic-associated diarrhea...

Read the full Saccharomyces Boulardii monograph → Herb & supplement monograph

Inulin

Interacts with 86 drugs

Inulin is a type of plant fiber (a prebiotic) found naturally in foods like chicory root, onions, and garlic, and it is widely added to supplements and processed foods. It may help with regu...

Read the full Inulin monograph →
Sources

Sources & How We Checked

Bifidus Power Blend's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 80 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bifidobacterium Bifidum 7 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
  3. Rerksuppaphol S, Rerksuppaphol L. Randomized controlled trial of probiotics to reduce common cold in schoolchildren. Pediatr Int. 2012;54(5):682-7. PubMed
  4. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  5. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  6. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  7. Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed

See these in context on the Bifidobacterium Bifidum monograph →

Bifidobacterium Longum 21 references
  1. Ha GY, Yang CH, Kim H, Chong Y. Case of sepsis caused by Bifidobacterium longum. J Clin Microbiol 1999;37:1227-8.
  2. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  3. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
  4. Rautava S, Kainonen E, Salminen S, Isolauri E. Maternal probiotic supplementation during pregnancy and breast-feeding reduces the risk of eczema in the infant. J Allergy Clin Immunol. 2012;130(6):1355-60. PubMed
  5. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  6. Pellonperä O, Vahlberg T, Mokkala K, et al. Weight gain and body composition during pregnancy: a randomised pilot trial with probiotics and/or fish oil. Br J Nutr. 2020 Nov 4:1-11. PubMed
  7. Pellonperä O, Mokkala K, Houttu N, et al. Efficacy of fish oil and/or probiotic intervention on the incidence of gestational diabetes mellitus in an at-risk group of overweight and obese women: A randomized, placebo-controlled, double-blind clinical trial PubMed
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
  10. Enomoto T, Sowa M, Nishimori K, et al. Effects of bifidobacterial supplementation to pregnant women and infants in the prevention of allergy development in infants and on fecal microbiota. Allergol Int 2014;63(4):575-85. PubMed
  11. US Food and Drug Administration (FDA). Dear Healthcare Provider Letter: Warning Regarding Use of Probiotics in Preterm Infants. September 2023. Available at: https://www.fda.gov/media/172606/download?attachment. Accessed November 1, 2023.
  12. Pillai A, Tan J, Paquette V, Panczuk J. Does probiotic bacteremia in premature infants impact clinically relevant outcomes? A case report and updated review of literature. Clin Nutr ESPEN. 2020;39:255-259. PubMed
  13. Sabaté JM, Iglicki F. Effect of Bifidobacterium longum 35624 on disease severity and quality of life in patients with irritable bowel syndrome. World J Gastroenterol 2022;28(7):732-744.
  14. Malaguarnera M, Greco F, Barone G, Gargante MP, Malaguarnera M, Toscano MA. Bifidobacterium longum with fructo-oligosaccharide (FOS) treatment in minimal hepatic encephalopathy: a randomized, double-blind, placebo-controlled study. Dig Dis Sci 2007;52(11) PubMed
  15. Zbinden A, Zbinden R, Berger C, Arlettaz R. Case series of Bifidobacterium longum bacteremia in three preterm infants on probiotic therapy. Neonatology 2015;107(1):56-9.
  16. Tamaki H, Nakase H, Inoue S, et al. Efficacy of probiotic treatment with Bifidobacterium longum 536 for induction of remission in active ulcerative colitis: A randomized, double-blinded, placebo-controlled multicenter trial. Dig Endosc 2016;28(1):67-74.
  17. Bertelli C, Pillonel T, Torregrossa A, et al. Bifidobacterium longum bacteremia in preterm infants receiving probiotics. Clin Infect Dis 2015;60(6):924-7. PubMed
  18. Esaiassen E, Cavanagh P, Hjerde E, Simonsen GS, Støen R, Klingenberg C. Bifidobacterium longum subspecies infantis bacteremia in 3 extremely preterm infants receiving probiotics. Emerg Infect Dis 2016;22(9):1664-6.
  19. Tena D, Losa C, Medina MJ, Sáez-Nieto JA. Peritonitis caused by Bifidobacterium longum: case report and literature review. Anaerobe 2014;27:27-30. PubMed
  20. Sangkanjanavanich S, Pradubpongsa P, Mitthamsiri W, Sangasapaviliya A, Boonpiyathad T. Bifidobacterium infantis 35624 efficacy in patients with uncontrolled asthma: A randomized placebo-controlled trial. Ann Allergy Asthma Immunol 2022;129(6):790-792. PubMed
  21. Wilson HL, Ong CW. Bifidobacterium longum vertebrodiscitis in a patient with cirrhosis and prostate cancer. Anaerobe 2017;47:47-50. PubMed

See these in context on the Bifidobacterium Longum monograph →

Bifidobacterium Breve 9 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
  3. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  4. Ohishi A, Takahashi S, Ito Y, et al. Bifidobacterium septicemia associated with postoperative probiotic therapy in a neonate with omphalocele. J Pediatr. 2010;156(4):679-81. PubMed
  5. Sakurai Y, Watanabe T, Miura Y, et al. Clinical and bacteriologic characteristics of six cases of Bifidobacterium breve bacteremia due to probiotic administration in the neonatal intensive care unit. Pediatr Infect Dis J 2022;41(1):62-65. PubMed
  6. Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
  7. Wakabayashi Y, Nakayama S, Yamamoto A, et al. First case of necrotizing fasciitis and bacteremia caused by Bifidobacteriumbreve. Anaerobe 2022;76:102613.
  8. Takeda Y, Ota K, Kondo A, et al. A case of necrotizing fasciitis caused by Bifidobacterium breve. IDCases 2022;31:e01667. PubMed
  9. Suwantarat N, Romagnoli M, Wakefield T, Carroll KC. Ventriculoperitoneal shunt infection caused by Bifidobacterium breve. Anaerobe 2014;28:1-3. PubMed

See these in context on the Bifidobacterium Breve monograph →

Saccharomyces Boulardii 26 references
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  20. Roy U, Jessani LG, Rudramurthy SM, et al. Seven cases of Saccharomyces fungaemia related to use of probiotics. Mycoses 2017;60(6):375-380.
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See these in context on the Saccharomyces Boulardii monograph →

Inulin 17 references
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See these in context on the Inulin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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