Major interaction on record — check this product against your medications before combining. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Bio-Available Mucuna Extract Ingredients & Drug Interactions

by Herbadiet

Bio-Available Mucuna Extract label
See full label image
Capsule Category: Botanical
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Bio-Available Mucuna Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Bio-Available Mucuna Extract is a dietary supplement by Herbadiet with 2 active ingredients. Its ingredients are commonly taken for parkinson's disease symptoms, male fertility and libido, mood and stress support.Based on those ingredients, 193 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Mucuna Seed Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Bio-Available Mucuna Extract by Herbadiet

Ask about any prescription or over-the-counter medication and we check it for interactions with Bio-Available Mucuna Extract by Herbadiet — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Bio-Available Mucuna Extract by Herbadiet

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product has 2 active ingredients, both from the mucuna plant: Mucuna Seed Extract and Mucuna. Both contain levodopa, a naturally occurring compound that acts like an active drug in your body and affects dopamine—a brain chemical involved in movement, mood, and other functions.

The capsule shell itself is vegetable cellulose, an inactive ingredient.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Cowhage's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: enhance brain function and mood.
  • We looked for evidence on: Anxiety, Parkinson disease, cognitive function, mood support, nervous system health.
  • The closest evidence on file: Cowhage is rated "Insufficient Reliable Evidence To Rate" for Anxiety (Natural Medicines).
  • Also on file: Cowhage is rated "Insufficient Reliable Evidence To Rate" for Parkinson disease.

The evidence we hold doesn't establish how well this product works. For all the uses listed—anxiety, erythema (skin redness), high prolactin levels, muscle pain, Parkinson disease, and rheumatoid arthritis—the data shows insufficient reliable evidence to rate its effectiveness.

That doesn't mean it doesn't work; it means we don't have solid research data on it yet.

The evidence, ingredient by ingredient Cowhage

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Adverse effects seem rare overall, but a full safety review hasn't been completed. The most common side effects reported when taken by mouth are diarrhea, flatulence, and stomach irritation.

Some people report dry mouth and headaches. At higher doses (22.5–67.5 grams divided into multiple doses daily), clinical research noted nausea, abdominal bloating, vomiting, and insomnia in about 3% of participants.

Because this product contains levodopa—an active drug-like compound—it should be used carefully under professional guidance. The safety data advises against it during pregnancy due to insufficient safety information and its dopamine effects.

While breastfeeding, avoid it; levodopa can lower prolactin levels and reduce milk supply.

Side effects, ingredient by ingredient Cowhage

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Cowhage.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: diabetes medications; Parkinson's medications.
  • For scale: 193 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, double-check with your pharmacist if you're on methyldopa, MAOIs, or levodopa—these are Major-severity interactions. Also check blood sugar medications, antipsychotics, tricyclic antidepressants, certain surgical anesthetics, or guanethidine.

No interactions are documented for any ingredients we could not check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Major medication interactions have been identified, and safety information is well characterized.

This is a supplement that acts like medication because of its levodopa content, so it's not for everyone. If you take any blood pressure medication, antidepressants, diabetes medication, antipsychotics, or are having surgery, talk to your pharmacist or doctor before you start it.

It's particularly important to check if you're on an MAOI or already taking levodopa.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 18, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Bio-Available Mucuna Extract, straight from the product label.

Brand Herbadiet
Barcode (UPC) 880416130443
Net contents 60 V-Cap(s)
Market status On market
Date entered into DSLD Dec 18, 2021
DSLD ID 257409
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Bio-Available Mucuna Extract by Herbadiet, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 V-Cap(s)
Maximum serving Sizes:
2 V-Cap(s)
Servings per container
30
UPC/BARCODE
880416130443
IngredientAmount% DV
Mucuna Seed Extract600 mg--
Mucuna200 mg--

Other ingredients: Vegetable Cellulose Shell

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Herbadiet Bio-available Mucuna is a high potency, water soluble, 10:1 concentrated extract. This full spectrum extract retains all the active constituents in nature intended balanced ratio. Encapsulating this goodness in our quick release, easy to swallow vegan capsules, guarantees you a premium quality nutritional supplement.

Formulation

Enhances brain functions Elevates mood & refines the senses Soothe the nervous system

Natural color variation may occur in this product

100% natural Brain support

Non-GMO

Suitable for vegetarians and vegans

Free of preservatives, binders, gluten, artificial ingredients, dairy, soy, wheat, yeast

Every batch 3rd party lab tested

FDA Disclaimer Statement

These statements have not been evaluated by FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Do not use if seal under the cap is broken or missing. Dietary supplement shouldn't be used as a substitute for a varied diet

Caution: If you are pregnant, breast feeding, or taking medications, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Keep out of reach of children.

Storage

Store in cool, dry place

General Statements

Not for medicinal use

1% for the planet

License Number : 10018064001315

Seals/Symbols

fssai Lic. No.: 20817018000147 Vcaps Plus GMP Good Manufacturing Practice Quality Product

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions for Use: Take 2 capsules daily, preferably with meals or as directed by your physician. Best when taken early in a day

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Bio-Available Mucuna Extract by Herbadiet label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Bio-Available Mucuna Extract label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Bio-Available Mucuna Extract by Herbadiet

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 V-Cap(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Mucuna Seed Extract

Interacts with
193 drugs
600 mg per serving

Cowhage (Mucuna pruriens) is a tropical legume best known as a natural source of L-dopa, the compound the body turns into dopamine. It is most studied...

Mucuna Seed Extract monograph & interactions

Mucuna

Interacts with
193 drugs
200 mg per serving

Cowhage (Mucuna pruriens) is a tropical legume best known as a natural source of L-dopa, the compound the body turns into dopamine. It is most studied...

Mucuna monograph & interactions

Other (inactive) ingredients: Vegetable Cellulose Shell. These complete the product’s ingredient list but are not active constituents.

Interaction report

Bio-Available Mucuna Extract by Herbadiet Drug Interactions

Want to check YOUR meds against Bio-Available Mucuna Extract?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
193Drugs
17 Major 176 Moderate

Ingredients driving the most interactions

Mucuna Seed Extract 193

Individual Drug Interactions

The ingredients in Bio-Available Mucuna Extract interact with 193 drugs. Click any drug to see the details.

1 of the 2 ingredients in Bio-Available Mucuna Extract interact with drugs. Each result below shows which ingredient is responsible. Mucuna Seed Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Bio-Available Mucuna Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Mucuna Seed Extract8 drug types · 193 drugs

Levodopa

Concomitant use can increase the risk of levodopa-related adverse effects.
Cowhage contains levodopa. Some cowhage products have been standardized to contain 75-400 mg of levodopa per dose.

Likelihood Likely Evidence D
Methyldopa (Aldomet)

Theoretically, concomitant use of cowhage and methyldopa might increase the risk of hypotension.
Cowhage contains levodopa. Use of levodopa with methyldopa might cause additive hypotension. In addition, methyldopa may inhibit peripheral decarboxylation of levodopa and increase levodopa levels in the central nervous system; avoid using.

Likelihood Probable Evidence D
Monoamine Oxidase Inhibitors (Maois)

Theoretically, concomitant use of cowhage and non-selective MAOIs might increase the risk of hypertensive crisis.
Cowhage contains levodopa. Use of levodopa with non-selective MAOIs might cause hypertensive crisis. However, this interaction has not been reported with MAO-B selective inhibitors such as selegiline.

Likelihood Probable Evidence D
Anesthesia

Theoretically, concomitant use of cowhage and anesthesia might increase the risk of arrhythmias.
Cowhage contains levodopa. Use of levodopa with cyclopropane or halogenated hydrocarbon anesthesia has led to arrhythmias. Other anesthetics have not been implicated. Use other anesthetics in patients taking cowhage or tell patients to stop taking cowhage at least 2 weeks before surgery.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, concomitant use of cowhage and antidiabetes drugs might increase the risk of hypoglycemia.
Animal research shows that cowhage might have hypoglycemic effects.

Likelihood Possible Evidence D
Antipsychotic Drugs

Theoretically, use of cowhage might decrease the clinical effects of antipsychotic drugs.
Cowhage contains levodopa. Use of levodopa might counteract the antidopaminergic effects of antipsychotic medications.

Likelihood Possible Evidence D
Guanethidine (Ismelin)

Theoretically, concomitant use of cowhage and guanethidine might increase the risk of hypotension.
Cowhage contains levodopa. Use of levodopa with guanethidine might cause additive hypotension; avoid using.

Likelihood Probable Evidence D
Tricyclic Antidepressants (Tcas)

Theoretically, use of TCAs might reduce the levels and clinical effects of cowhage.
Cowhage contains levodopa. Use of TCAs might reduce the absorption of levodopa. Some case reports describe patients that developed hypertension and dyskinesia when taking both levodopa and TCAs.

Likelihood Possible Evidence D
Mucuna Seed Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Bio-Available Mucuna Extract, from the product label.

Herbadiet

See all Herbadiet products
Name
Arkure Health Care
City
Haryana
State
India
Web Address
www.herbadiet.in
Pharmacist Counseling Corner

Bio-Available Mucuna Extract by Herbadiet: Common Questions

Does Bio-Available Mucuna Extract by Herbadiet interact with any medications?
Yes. Based on its ingredients, Bio-Available Mucuna Extract has a known interaction with 193 medications, including 17 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Bio-Available Mucuna Extract contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take during pregnancy?
No. The safety data advises against it during pregnancy because there isn't enough safety information and the levodopa it contains affects dopamine in ways that may not be safe for your baby. Talk with your doctor before considering it.
Can I take this while breastfeeding?
No. The levodopa in this product can lower prolactin levels and reduce your milk supply, so you should avoid it while breastfeeding.
What side effects might I get from this?
The most common ones reported are diarrhea, flatulence, and stomach irritation. Some people also report dry mouth and headaches. At higher doses used in research, nausea, bloating, vomiting, and trouble sleeping were noted in a small number of participants.
Does this really work for Parkinson disease, anxiety, or other conditions listed?
The evidence we have isn't strong enough to say. For all six conditions mentioned—Parkinson disease, anxiety, muscle pain, skin redness, high prolactin, and rheumatoid arthritis—the data shows insufficient reliable evidence to rate how well it works.
Why does it interact with so many medications?
Both active ingredients contain levodopa, which mimics and affects dopamine, a brain chemical involved in many body systems. That's why it can affect blood pressure drugs, antidepressants, blood sugar control, antipsychotics, and surgery medications.
What is levodopa and why is it in a supplement?
Levodopa is a naturally occurring compound in the mucuna plant that your body converts to dopamine. It's included because the manufacturer believes it can support certain health goals, but because it acts like a drug, it needs careful use and professional guidance.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Bio-Available Mucuna Extract is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Bio-Available Mucuna Extract label
Go deeper

The Full Monographs Behind Bio-Available Mucuna Extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Cowhage

Interacts with 193 drugs

Cowhage (Mucuna pruriens) is a tropical legume best known as a natural source of L-dopa, the compound the body turns into dopamine. It is most studied for Parkinson's disease symptoms and ma...

Read the full Cowhage monograph →
Sources

Sources & How We Checked

Bio-Available Mucuna Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Cowhage 12 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Anon. Epidemiological notes and reports: Mucuna pruriens-associated pruritus--New Jersey. MMWR Morb Mortal Wkly Rep 1985;34:732-3.
  4. HP-200 in Parkinson's Disease study group. An alternative medicine treatment for Parkinson's disease: Results of a multicenter clinical trial. J Alt Comp Med 1995;1:249-55. DOI
  5. Infante ME, Perez AM, Simao MR, et al. Outbreak of acute toxic psychosis attributed to Mucuna pruriens. Lancet 1990;336:1129. PubMed
  6. Vaidya AB, Rajagopalan TG, Mankodi NA, et al. Treatment of Parkinson's disease with the cowhage plant-Mucuna pruriens Bak. Neurol India 1978;26:171-6.
  7. Vadivel V, Janardhanan K. Nutritional and anti-nutritional composition of velvet bean: an under-utilized food legume in south India. Int J Food Sci Nutr 2000;51:279-87. PubMed
  8. Akhtar MS, Qureshi AQ, Iqbal J. Antidiabetic evaluation of Mucuna pruriens, Linn seeds. J Pak Med Assoc 1990;40:147-50.
  9. Prakash, D., Niranjan, A., and Tewari, S. K. Some nutritional properties of the seeds of three Mucuna species. Int.J.Food Sci.Nutr. 2001;52(1):79-82.
  10. Vadivel, V. and Janardhanan, K. Nutritional and antinutritional characteristics of seven South Indian wild legumes. Plant Foods Hum.Nutr 2005;60(2):69-75. PubMed
  11. Creapure (Creatine Monohydrate). Toxicological Datasheet. Degussa BioActives. Available at: https://www.fda.gov/ohrms/DOCKETS/.../95s-0316-rpt0154-54-Ref-50-vol112.pdf.
  12. Pulikkalpura H, Kurup R, Mathew PJ, Baby S. Levodopa in Mucuna pruriens and its degradation. Sci Rep 2015;5:11078. PubMed

See these in context on the Cowhage monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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