Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Black Elderberry Elixir Extract Ingredients & Drug Interactions

by Oregon's Wild Harvest

Liquid Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Black Elderberry Elixir Extract is a dietary supplement by Oregon's Wild Harvest with 1 active ingredient. Its ingredients are commonly taken for colds, flu (influenza), other respiratory infections.Based on those ingredients, 121 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Black Elderberry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Black Elderberry Elixir Extract by Oregon's Wild Harvest

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: black elderberry extract in liquid form. The extract is prepared from ripe fruit and suspended in a base of alcohol, glycerin, raspberry juice concentrate, and citrus extract.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: immune support and respiratory health.
  • We looked for evidence on: Upper respiratory tract infection (URTI), Lower respiratory tract infections, Respiratory tract infections, Rhinosinusitis, Colds, Influenza — and 1 related terms.
  • The closest evidence on file: Elderberry is rated "Insufficient Reliable Evidence To Rate" for Lower respiratory tract infections (Natural Medicines).
  • Also on file: Elderberry is rated "Insufficient Reliable Evidence To Rate" for Rhinosinusitis.

The evidence we hold does not establish how well black elderberry works for any of its common uses — allergic rhinitis (hay fever), heart disease prevention, chronic fatigue, lung disease, brain function, or fighting off respiratory infections. The data on file rates all of these as having insufficient reliable evidence.

That doesn't mean it doesn't work; it means large, rigorous studies haven't confirmed it yet.

The evidence, ingredient by ingredient Elderberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Properly prepared elderberry products made from ripe fruit are generally well tolerated. However, raw or unripe berries, seeds, leaves, and bark can be toxic and may cause nausea, vomiting, severe diarrhea, weakness, dizziness, numbness, and confusion — cooking eliminates this risk.

One case report linked long-term elderberry use to autoimmune hepatitis (liver inflammation) in a person with an underlying autoimmune disease; the condition resolved after stopping the supplement. There isn't enough safety data to know whether elderberry is safe during pregnancy or while breastfeeding, so it's best to avoid it in these situations.

Talk with your doctor or pharmacist if you're pregnant, planning to become pregnant, or nursing.

Side effects, ingredient by ingredient Elderberry

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Elderberry.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs.
  • For scale: 121 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this, double-check if you're on an immunosuppressant medication (something that weakens your immune system after a transplant or for certain diseases) or pazopanib (a cancer drug). Both have Moderate-severity interactions documented with elderberry.

Use the tool on this page to search your specific medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Black elderberry extract is generally well tolerated when made from ripe fruit, but evidence for its effectiveness isn't established in our data. If you take an immunosuppressant medication or pazopanib, check with your pharmacist before starting.

And if you're pregnant or breastfeeding, skip it and talk with your provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Black Elderberry Elixir Extract, straight from the product label.

Brand Oregon's Wild Harvest
Barcode (UPC) 706195014012
Net contents 1 Fluid Ounce(s); 30 mL
Market status On market
Date entered into DSLD Oct 24, 2024
DSLD ID 317149
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Organic, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Black Elderberry Elixir Extract by Oregon's Wild Harvest, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
30
UPC/BARCODE
706195014012
IngredientAmount% DV
Black Elderberry250 mg--

Other ingredients: Alcohol, Glycerin, Raspberry juice concentrate, Citrus Extract

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Organic to our roots Certified organic since 1994, our regenerative practices heal the planet while providing potent herbs today and for future generations.

Formulation

Free from: Gluten, dairy and soy allergens.

Organic USDA Organic Certified Organic by Oregon Tilth.

Be well, stay well

Non GMO GF (Gluten free)

Precautions

Caution: Keep out of reach of children.

Do not take if pregnant or nursing. If taking medication consult a healthcare professional before use.

Discontinue use if unusual symptoms occur.

Do not exceed recommended dose.

Suggested/Recommended/Usage/Directions

Shake well.

Suggested use: Take 1 mL three times daily in warm water within 24 to 48 hours of symptom onset or as directed by your healthcare professional. 1 mL = approx. 30 drops.

Storage

Store upright in a cool, dry place.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Brand IP Statement(s)

Oregon's Wild Harvest since 1994

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

USDA Organic

Oregon Tilth Certified Organic (OTCO)

Formula

Alcohol content: Not more than 25%.

See for yourself

Black Elderberry Elixir Extract by Oregon's Wild Harvest label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Black Elderberry Elixir Extract by Oregon's Wild Harvest

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container30 Amounts shown are per serving.

Black Elderberry

Interacts with
121 drugs
250 mg per serving Form: Sambucus nigra

Elderberry is a popular herbal supplement, mainly taken to help with colds and flu. Some small studies suggest it may modestly shorten cold or flu sym...

Black Elderberry monograph & interactions

Other (inactive) ingredients: Alcohol, Glycerin, Raspberry juice concentrate, Citrus Extract. These complete the product’s ingredient list but are not active constituents.

Interaction report

Black Elderberry Elixir Extract by Oregon's Wild Harvest Drug Interactions

Want to check YOUR meds against Black Elderberry Elixir Extract?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
121Drugs
121 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Black Elderberry Elixir Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Black Elderberry2 drug types · 121 drugs

Immunosuppressants

Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Elderberry has immunostimulant activity, increasing the production of cytokines, including interleukin and tumor necrosis factor.

Likelihood Possible Evidence B
Pazopanib (Votrient)

Theoretically, elderberry might interact with pazopanib, potentially increasing the risk of adverse effects.
In one case, a 65-year-old patient taking pazopanib for 4 weeks for soft-tissue sarcoma developed severe nausea, loose stools, and elevated alanine transaminase and aspartate transaminase levels and was diagnosed with grade 3 liver injury. The patient reported taking elderberry supplements for 2 years, dose unspecified, and was also taking a multivitamin and a calcium supplement. The patient's symptoms and liver enzyme levels improved upon discontinuation of pazopanib and all supplements. Pazopanib treatment was re-initiated, at a lower dose, with no further evidence of liver injury. It was unclear in this case report if the elderberry supplements were derived from the berry, the flower, or the combination.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Black Elderberry Elixir Extract, from the product label.

Oregon's Wild Harvest

See all Oregon's Wild Harvest products
Name
Oregon's Wild Harvest
City
Redmond
State
OR
ZipCode
97756
Phone Number
800-316-6869
Web Address
oregonswildharvest.com
Pharmacist Counseling Corner

Black Elderberry Elixir Extract by Oregon's Wild Harvest: Common Questions

Does Black Elderberry Elixir Extract by Oregon's Wild Harvest interact with any medications?
Yes. Based on its ingredients, Black Elderberry Elixir Extract has a known interaction with 121 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Black Elderberry Elixir Extract contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take while I'm pregnant?
There isn't enough reliable safety information to know, so the data advises against it. Talk with your doctor or pharmacist about what's right for you.
Can I take this if I'm breastfeeding?
There isn't enough safety data either way, so it's best to avoid it. Check with your pharmacist or doctor for personalized advice.
Does elderberry actually prevent colds or flu?
The evidence we have doesn't establish that it works for respiratory infections. That doesn't mean it can't — just that large, rigorous studies haven't confirmed it yet.
What should I watch out for with side effects?
When made from ripe fruit like this one, it's generally well tolerated. The risks come from raw or unripe berries, seeds, leaves, and bark, which can cause nausea, vomiting, diarrhea, and dizziness — but cooking eliminates that problem. One rare case linked long-term use to liver inflammation in someone with an autoimmune disease.
Is the alcohol in this a problem?
The product facts we hold don't address alcohol content or concerns, so we can't say. If you need to avoid alcohol — for health reasons, recovery, or medication interactions — ask your pharmacist about the specific amount in this elixir.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Black Elderberry Elixir Extract is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Black Elderberry Elixir Extract label
Go deeper

The Full Monographs Behind Black Elderberry Elixir Extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Black Elderberry Elixir Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Elderberry 6 references
  1. Barak V, Halperin T, Kalickman I. The effect of Sambucol, a black elderberry-based, natural product, on the production of human cytokines: I. Inflammatory cytokines. Eur Cytokine Netw 2001;12:290-6..
  2. Elderberry (Sambucus species). The Poison Plant Patch, Novia Scotia Museum, 2007. Available at: http://museum.gov.ns.ca/poison/?section=species&id=117 (Accessed 16 October 2009).
  3. European elder. Canadian Poisonous Plants Information System. Available at: http://www.cbif.gc.ca/pls/pp/ppack.jump?p_null=all&p_psn=121&p_type=all&p_sci=comm&p_x=px (Accessed 16 October 2009).
  4. Raus K, Pleschka S, Klein P, Schoop R, Fisher P. Effect of an echinacea-based hot drink versus oseltamivir in Influenza treatment: a randomized, double-blind, double-dummy, multicenter, noninferiority clinical trial. . Curr Ther Res Clin Exp. 2015;20;77:6 PubMed
  5. Ramachandran A, Antala D, Pudasainee P, Panginikkod S, Gupta H. A Plausible Association Between the Use of Elderberry and Autoimmune Hepatitis. Cureus 2022;14(4):e24250. PubMed
  6. Agarwal N, Mangla A. Elderberry interaction with pazopanib in a patient with soft-tissue sarcoma: A case report and literature review. Mol Clin Oncol 2024;20(5):36. PubMed

See these in context on the Elderberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring