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Dietary supplement

Boswellia Capsules 500 mg Ingredients & Drug Interactions

by Herbal Hills

Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Boswellia Capsules 500 mg is a dietary supplement by Herbal Hills with 1 active ingredient. Its ingredients are commonly taken for osteoarthritis joint pain, rheumatoid arthritis, inflammation.Based on those ingredients, 952 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Boswellia Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Boswellia Capsules 500 mg by Herbal Hills

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Boswellia Extract, derived from Boswellia serrata, a resin from a tree used in traditional medicine. It's packaged in veggie capsules with silicon dioxide (an anti-caking agent) as the only other ingredient.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: support joint health and maintain healthy lipid levels.
  • We looked for evidence on: Osteoarthritis, Rheumatoid arthritis (RA), Knee pain, Joint inflammation, Cartilage support, Mobility.
  • The strongest evidence on file: Boswellia Serrata is rated "Possibly Effective" for Osteoarthritis (Natural Medicines).
  • Also on file: Boswellia Serrata is rated "Insufficient Reliable Evidence To Rate" for Rheumatoid arthritis (RA), Knee pain.

Boswellia shows possibly effective evidence for osteoarthritis—meaning some research supports its use, though more data would help confirm it. For allergic rhinitis (hay fever), asthma, Alzheimer disease, and cluster headache, the evidence we hold isn't established well enough to rate it.

If you're considering Boswellia for one of those other conditions, talk it over with your doctor to see what research exists and whether it makes sense for you.

The evidence, ingredient by ingredient Boswellia Serrata

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Boswellia extract is generally well tolerated when taken by mouth short-term, though quality and dose vary widely between products—so consistency can be an issue. The most common side effects are mild: abdominal pain, diarrhea, headache, heartburn, itching, and nausea.

Dizziness and vertigo have also been reported in clinical studies. One rare but serious risk: very large amounts of boswellia gum resin can form a bezoar (a blockage in your gut).

During pregnancy, there isn't enough safety data, so it's best avoided. The same goes for breastfeeding—safety is unknown, so avoid it while nursing.

Side effects, ingredient by ingredient Boswellia Serrata

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Boswellia Serrata.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs.
  • For scale: 953 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you take immunosuppressants (drugs given after transplant or for autoimmune conditions). Also flag any antidepressants, blood-pressure medications, heart drugs, or other prescriptions metabolized by CYP2D6, CYP2C19, CYP1A2, CYP2C9, or CYP3A4 enzymes—Boswellia may raise their levels in your body.

Use the medication checker on this page to search your specific drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Boswellia may help with osteoarthritis, but it's not a light supplement when it comes to medications—it can affect how your body processes a wide range of drugs through multiple liver pathways. If you take any prescription medication, immunosuppressants especially, check it with your doctor or pharmacist before you start.

It's generally well tolerated on its own, and it's not recommended in pregnancy or while breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 16, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Boswellia Capsules 500 mg, straight from the product label.

Brand Herbal Hills
Barcode (UPC) 8904268849710
Net contents 120 Veggie Cap(s)
Market status On market
Date entered into DSLD Jun 16, 2022
DSLD ID 268318
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Halal
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Boswellia Capsules 500 mg by Herbal Hills, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Veggie Cap(s)
Maximum serving Sizes:
2 Veggie Cap(s)
Servings per container
60
UPC/BARCODE
8904268849710
IngredientAmount% DV
Boswellia Extract500 mg--

Other ingredients: Veggie Capsule, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Boswellia is a traditional herb also known as Shallaki/Salai Guggul. Boswellia is considered to act as a natural support for joint health. It may help to maintain healthy lipid levels.

Boswellia Capsules 500mg per serving

Halal

Formulation

Contents based on standard Raw Material as per Traditional Text

Being natural product, colour may vary over time as well as from batch to batch however effectiveness remains same.

Pure Natural Effective

We adhere to Non-GMO standards

Country of Origin: India

Suggested/Recommended/Usage/Directions

Directions for Use: As a dietary supplement, take 2 veggie capsules a day with meals or as directed by your health care practitioner.

Precautions

Warning: Pregnant or lactating women are advised to consume herbal products under the advice of the healthcare practitioner.

Keep out of reach of children.

Do not use if pouch is broken.

Please consult an expert before use.

Storage

Storage: Store in a cool dry place away from direct sunlight.

General Statements

MRP is applicable for sales within India only.

Neutral Code: MH/PD/AYU/002/10

FDA Disclaimer Statement

These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Brand IP Statement(s)

Herbal Hills Back to Nature

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

QA ICS JAS-ANZ GMP Good Manufacturing Practice Halal India HIW21081110

See for yourself

Boswellia Capsules 500 mg by Herbal Hills label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Boswellia Capsules 500 mg by Herbal Hills

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Veggie Cap(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Boswellia Extract

Interacts with
952 drugs
500 mg per serving Form: Boswellic Acids

Boswellia serrata is a tree resin used in traditional medicine, mainly for joint pain and inflammation. Some studies suggest it may help with osteoart...

Boswellia Extract monograph & interactions

Other (inactive) ingredients: Veggie Capsule, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Boswellia Capsules 500 mg by Herbal Hills Drug Interactions

Want to check YOUR meds against Boswellia Capsules 500 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
952Drugs
952 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Boswellia Capsules 500 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Boswellia Extract6 drug types · 952 drugs

Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, Boswellia serrata might increase the levels of CYP1A2 substrates.
In vitro research shows that Boswellia serrata gum resin inhibits CYP1A2 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, Boswellia serrata might increase the levels of CYP2C19 substrates.
In vitro research shows that Boswellia serrata gum resin inhibits CYP2C19 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, Boswellia serrata might increase the levels of CYP2C9 substrates.
In vitro research shows that Boswellia serrata gum resin inhibits CYP2C9 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, Boswellia serrata might increase the levels of CYP2D6 substrates.
In vitro research shows that Boswellia serrata gum resin inhibits CYP2D6 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, Boswellia serrata might increase or decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that Boswellia serrata gum resin inhibits CYP3A4 enzymes. Other in vitro research shows that Boswellia serrata extract inhibits CYP3A4 enzymes at most concentrations, although it may modestly induce enzyme activity at low concentrations.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, Boswellia serrata might alter the effects of immunosuppressive drugs.
Some in vitro research suggests that Boswellia serrata extracts might inhibit mediators of autoimmune disorders such as leukotrienes and reduce production of antibodies and cell-mediated immunity. However, other in vitro research suggests that, when coupled with calcium ions, boswellic acids containing the keto group have immunostimulant properties within specific cell signaling pathways.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Boswellia Capsules 500 mg, from the product label.

Herbal Hills

See all Herbal Hills products
Name
Stelcore Management Services LLC (Importer)
Street Address
8 Green Suite 5766
City
Dover
State
Delaware
ZipCode
19901
Pharmacist Counseling Corner

Boswellia Capsules 500 mg by Herbal Hills: Common Questions

Does Boswellia Capsules 500 mg by Herbal Hills interact with any medications?
Yes. Based on its ingredients, Boswellia Capsules 500 mg has a known interaction with 952 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Boswellia Capsules 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while I'm pregnant or breastfeeding?
Not during pregnancy—there isn't enough safety data, so it's best avoided. If you're breastfeeding, safety is unknown, so it's best to avoid that too. Talk with your doctor or pharmacist about whether it's right for you at those times.
What side effects might I get?
Most people who take it experience mild side effects: stomach pain, diarrhea, headache, heartburn, itching, or nausea. Dizziness and vertigo have been reported too. In rare cases, very large amounts can form a blockage in your gut, so stick to the recommended dose.
Does Boswellia actually work for arthritis?
For osteoarthritis, the evidence suggests it possibly works—some research supports it, though we'd like more data. For other conditions like hay fever, asthma, or Alzheimer disease, the evidence we hold isn't established well enough yet.
Why does the product page mention so many drug interactions?
Boswellia extract can slow down several liver enzymes that break down many common medications. That means those drugs might build up in your body and become stronger than intended. That's why it's important to check your exact medications before you start.
What's in these capsules besides Boswellia?
Just veggie capsule material and silicon dioxide (an anti-caking agent). The active ingredient is Boswellia extract at 500 mg per capsule.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Boswellia Capsules 500 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Boswellia Capsules 500 mg label
Sources

Sources & How We Checked

Boswellia Capsules 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 16 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Boswellia Serrata 16 references
  1. Gupta I, Gupta V, Parihar A, et al. Effects of Boswellia serrata gum resin in patients with bronchial asthma: results of a double-blind, placebo-controlled, 6-week clinical study. Eur J Med Res 1998;3:511-4.
  2. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  3. Kimmatkar N, Thawani V, Hingorani L, et al. Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee--a randomized double blind placebo controlled trial. Phytomedicine 2003;10:3-7. PubMed
  4. Liu JJ, Nilsson A, Oredsson S, et al. Boswellic acids trigger apoptosis via a pathway dependent on caspase-8 activation but independent on Fas/Fas ligand interaction in colon cancer HT-29 cells. Carcinogenesis 2002;23:2087-93. PubMed
  5. Wildfeuer A, Neu IS, Safayhi H, et al. Effects of boswellic acids extracted from a herbal medicine on the biosynthesis of leukotrienes and the course of experimental autoimmune encephalomyelitis. Arzneimittelforschung 1998;48:668-74.
  6. Gupta I, Parihar A, Malhotra P, et al. Effects of gum resin of Boswellia serrata in patients with chronic colitis. Planta Med 2001;67:391-5. PubMed
  7. Sengupta K, Alluri KV, Satish AR, et al. A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin. Arthritis Res Ther 2008;10:R85.
  8. Sengupta K, Krishnaraju AV, Vishal AA, et al. Comparative efficacy and tolerability of 5-Loxin and Aflapin against osteoarthritis of the knee: a double blind, randomized, placebo controlled clinical study. Int J Med Sci 2010;7:366-77.
  9. Ernst E. Frankincense: systematic review. BMJ 2008;337:a2813. PubMed
  10. Kirste S, Treier M, Wehrle SJ, et al. Boswellia serratea extract acts on cerebral edema in patients irradiated for brain tumors: a prospective, randomized, placebo-controlled, double-blind pilot trial. Cancer 2011;117:3788-95.
  11. Frank A, Unger M. Analysis of frankincense from various Boswellia species with inhibitory activity on human drug metabolising cytochrome P450 enzymes using liquid chromatography mass spectrometry after automated on-line extraction. J Chromatogr A 2006;111 PubMed
  12. Altmann A, Poeckel D, Fischer L, et al. Coupling of boswellic acid-incuded Ca2+ mobilisation and MAPK activation to lipid metabolism and peroxide formation in human leucocytes. Br J Pharmacol 2004;141:223-32.
  13. El Fortia, M., Badi, H., Elalem, Kh, Kadiki, O., and Topov, Y. Olibanum bezoar: complication of a traditional popular medicine. East Mediterr.Health J 2006;12(6):927-929.
  14. Meshkat S, Mahmoodi Baram S, Rajaei S, et al. Boswellia serrata extract shows cognitive benefits in a double-blind, randomized, placebo-controlled pilot clinical trial in individuals who suffered traumatic brain injury. Brain Inj 2022;36(4):553-559. PubMed
  15. Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
  16. Valente IVB, Garcia D, Abbott A, et al. The anti-proliferative effects of a frankincense extract in a window of opportunity phase ia clinical trial for patients with breast cancer. Breast Cancer Res Treat 2024;204(3):521-530. PubMed

See these in context on the Boswellia Serrata monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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