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Dietary supplement

Broccoli Extract with Glucosinolates Ingredients & Drug Interactions

by Swanson

Broccoli Extract with Glucosinolates label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Broccoli Extract with Glucosinolates against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Broccoli Extract with Glucosinolates is a dietary supplement by Swanson with 1 active ingredient. Its ingredients are commonly taken for general nutrition and antioxidant support, heart and digestive health, detoxification support.Based on those ingredients, 187 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are BroccoSinolate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Broccoli Extract with Glucosinolates by Swanson

Ask about any prescription or over-the-counter medication and we check it for interactions with Broccoli Extract with Glucosinolates by Swanson — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Broccoli Extract with Glucosinolates by Swanson

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: BroccoSinolate, a concentrated form of the glucosinolates naturally found in broccoli. Glucosinolates are the compounds in broccoli responsible for triggering changes in how your liver processes certain medications.

The capsule also contains three inactive ingredients—hypromellose, microcrystalline cellulose, and magnesium stearate—which are fillers and binders used to form the capsule.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Broccoli's overall clinical evidence instead.

Moderate

Some clinical evidence supports Broccoli for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Colorectal cancer — rated "Possibly Effective" (Natural Medicines).

The evidence for broccoli extract is incomplete. It's rated possibly effective for colorectal cancer, but for bladder cancer, breast cancer, fibromyalgia, and gastric cancer, the data we hold shows insufficient reliable evidence to know whether it works.

If you're considering this product for any of those cancer types or conditions, talk with your doctor about what the broader research suggests and whether it's right for your situation.

The evidence, ingredient by ingredient Broccoli

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Broccoli as a food is generally well tolerated, but concentrated supplements like this one are less studied. The safety data we hold advises caution: concentrated extracts aren't yet proven safe the way whole broccoli is.

At higher doses, some people have reported loose stools, diarrhea, stomach pain, and cramping. For pregnancy and lactation, broccoli is rated likely safe, though if you're pregnant or nursing and want to take a concentrated supplement, discuss it with your doctor or midwife to make sure it's right for your situation.

Side effects, ingredient by ingredient Broccoli

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Broccoli.
  • The most serious interaction on file is rated Moderate.
  • For scale: 187 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications against the list on this page, especially if you take drugs processed through CYP2A6 or CYP1A2 enzymes in your liver. These two enzyme systems together affect 187 individual medications—blood thinners, some heart drugs, certain antidepressants, and many others.

Your own doctor or pharmacist can tell you if any of yours are on that list.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

This extract is most important to check if you take medications that depend on liver enzymes CYP2A6 or CYP1A2 to work—which includes a broad range of common drugs. Before you start, run your medications through the checker on this page and talk with your doctor or pharmacist to confirm it won't interfere.

The evidence for its effectiveness isn't strong enough for most conditions we hold data on, so know what you're taking it for and whether the science supports that use.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Broccoli Extract with Glucosinolates, straight from the product label.

Brand Swanson
Barcode (UPC) 087614060354
Net contents 120 Veggie Capsule(s)
Market status On market
Date entered into DSLD Feb 22, 2024
DSLD ID 308525
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Broccoli Extract with Glucosinolates by Swanson, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Veggie Capsule(s)
Maximum serving Sizes:
1 Veggie Capsule(s)
Servings per container
120
UPC/BARCODE
087614060354
IngredientAmount% DV
BroccoSinolate600 mg--

Other ingredients: Hypromellose, Microcrystalline Cellulose, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Total wellness for mind, body & home Unsurpassed purity & potency 100% money back guaranteed

Vegetarian

Antioxidant support Green foods formula

Brand IP Statement(s)

Swanson Science-backed quality since 1969

BroccoSinolate is a registered trademark of Omega Protein Corporation, d/b/a Nutegrity.

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take one veggie capsule one to two times per day with water.

Precautions

Warning: For adults only. Keep out of reach of children.

Consult your healthcare provider before using this or any product if you are pregnant or nursing, taking medication or have a medical condition.

Do not use if seal is broken.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Herbal Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Broccoli Extract with Glucosinolates by Swanson label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Broccoli Extract with Glucosinolates label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Broccoli Extract with Glucosinolates by Swanson

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Veggie Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.

BroccoSinolate

Interacts with
187 drugs
600 mg per serving Form: Broccoli Floret, Seed, Sprout Extract, Broccoli Floret, Seed, Sprout Extract, Glucosinolates

Broccoli is a nutritious cruciferous vegetable rich in fiber, vitamins, and plant compounds like sulforaphane that have drawn scientific interest for...

BroccoSinolate monograph & interactions

Other (inactive) ingredients: Hypromellose, Microcrystalline Cellulose, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Broccoli Extract with Glucosinolates by Swanson Drug Interactions

Want to check YOUR meds against Broccoli Extract with Glucosinolates?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
187Drugs
187 Moderate

Ingredients driving the most interactions

BroccoSinolate 187

Individual Drug Interactions

The ingredients in Broccoli Extract with Glucosinolates interact with 187 drugs. Click any drug to see the details.

1 of the 1 ingredient in Broccoli Extract with Glucosinolates interact with drugs. Each result below shows which ingredient is responsible. BroccoSinolate

Each ingredient & the kinds of drugs it affects

For each ingredient in Broccoli Extract with Glucosinolates with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

BroccoSinolate2 drug types · 187 drugs

Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Pharmacokinetic research in humans shows that eating 500 grams of fresh broccoli daily for 6-12 days can increase CYP1A2 activity by 10% to 200%. Induction of CYP1A2 activity by broccoli is attributed to its glucosinolate constituents.

Likelihood Possible Evidence B
Cytochrome P450 2A6 (Cyp2A6) Substrates

Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP2A6.
Pharmacokinetic research in humans shows that eating 500 grams of broccoli daily for 6 days increases CYP2A6 activity by 135% to 550%. Induction of CYP2A6 activity is attributed to its glucosinolate constituents.

Likelihood Possible Evidence B
BroccoSinolate full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Broccoli Extract with Glucosinolates, from the product label.

Swanson

See all Swanson products
Name
Swanson Health Products
City
Fargo
State
ND
ZipCode
58104
Phone Number
1-800-437-4148
Web Address
swanson.com
Pharmacist Counseling Corner

Broccoli Extract with Glucosinolates by Swanson: Common Questions

Does Broccoli Extract with Glucosinolates by Swanson interact with any medications?
Yes. Based on its ingredients, Broccoli Extract with Glucosinolates has a known interaction with 187 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Broccoli Extract with Glucosinolates contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or nursing?
Broccoli itself is rated likely safe in pregnancy and lactation, but the safety of concentrated extracts is less certain. Talk with your doctor or midwife before starting any supplement during pregnancy or while breastfeeding to make sure it's appropriate for you.
What does BroccoSinolate do?
BroccoSinolate is a concentrated form of glucosinolates, compounds from broccoli that can change how quickly your liver clears certain medications. That's why this product interacts with so many drugs.
Does this work for cancer prevention?
Broccoli extract is rated possibly effective for colorectal cancer. For bladder cancer, breast cancer, and gastric cancer, we don't have enough reliable evidence to say whether it works. If you're interested in it for cancer prevention, talk with your doctor about the evidence and whether it fits your health plan.
What side effects should I watch for?
The most common side effects reported are loose stools, diarrhea, stomach pain, and cramping, especially at higher doses. These are usually mild, but if they're bothersome or don't improve, tell your doctor or pharmacist.
Is concentrated broccoli extract as safe as eating fresh broccoli?
Fresh broccoli as a food is well tolerated, but concentrated supplements like this one are less studied and the safety data advises caution. We don't yet have proof that extracts are as safe as whole broccoli, so talk with your doctor before starting.
Does this have fillers or other ingredients?
Yes, it contains three inactive ingredients: hypromellose, microcrystalline cellulose, and magnesium stearate. These are capsule binders and fillers, not the active ingredient.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Broccoli Extract with Glucosinolates is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Broccoli Extract with Glucosinolates label
Go deeper

The Full Monographs Behind Broccoli Extract with Glucosinolates’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Broccoli

Interacts with 187 drugs

Broccoli is a nutritious cruciferous vegetable rich in fiber, vitamins, and plant compounds like sulforaphane that have drawn scientific interest for health benefits. Eating broccoli as food...

Read the full Broccoli monograph →
Sources

Sources & How We Checked

Broccoli Extract with Glucosinolates's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Broccoli 5 references
  1. Kristal AR, Lampe JW. Brassica vegetables and prostate cancer risk: a review of the epidemiological evidence. Nutr Cancer 2002;42:1-9. PubMed
  2. Chakrabarti A, Prais L, Foulds IS. Allergic contact dermatitis to broccoli. Br J Dermatol 2003;148:172-3. PubMed
  3. Hakooz, N. and Hamdan, I. Effects of dietary broccoli on human in vivo caffeine metabolism: a pilot study on a group of Jordanian volunteers. Curr Drug Metab 2007;8(1):9-15. PubMed
  4. Kall MA, Vang O, Clausen J. Effects of dietary broccoli on human drug metabolising activity. Cancer Lett. 1997;114(1-2):169-70. PubMed
  5. Bauman JE, Hsu CH, Centuori S, et al. Randomized Crossover Trial Evaluating Detoxification of Tobacco Carcinogens by Broccoli Seed and Sprout Extract in Current Smokers. Cancers (Basel). 2022;14(9):2129. Published 2022 Apr 24. PubMed

See these in context on the Broccoli monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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