Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Chewable GABA Ingredients & Drug Interactions

by NOW

Chewable GABA label
See full label image
Tablet Or Pill Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Chewable GABA against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Chewable GABA is a dietary supplement by NOW with 4 active ingredients. Its ingredients are commonly taken for anxiety and stress, sleep problems, relaxation.Based on those ingredients, 651 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Theanine, GABA, Taurine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Chewable GABA by NOW

Ask about any prescription or over-the-counter medication and we check it for interactions with Chewable GABA by NOW — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Chewable GABA by NOW

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 4 of its 4 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This chewable tablet has four active ingredients. GABA is a natural brain chemical that works as a relaxant.

Taurine is an amino acid that supports heart and metabolic function. Inositol is a carbohydrate that plays a role in cell signaling and glucose control.

L-theanine is an amino acid from tea that promotes calm without drowsiness. The tablet also contains several inactive ingredients — binders, fillers, and flavoring — to hold it together and make it taste like orange.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: promote relaxation and calm.
  • We looked for evidence on: Anxiety, Generalized anxiety disorder (GAD), Panic disorder, Insomnia, Stress, Sleep quality — and 1 related terms.
  • The closest evidence on file: Inositol is rated "Possibly Ineffective" for Acute respiratory distress syndrome (ARDS) (Natural Medicines).
  • Also on file: Inositol is rated "Possibly Ineffective" for Anxiety.
  • Also on file: Inositol is rated "Insufficient Reliable Evidence To Rate" for Insomnia, Panic disorder, Post-traumatic stress disorder (PTSD).

The evidence for these ingredients is mixed. GABA has insufficient evidence to rate for anxiety, ADHD, and other common uses people try it for, meaning we don't have enough reliable studies yet.

Taurine is possibly effective for hepatitis and congestive heart failure, but possibly ineffective for weight loss. Inositol is possibly effective for polycystic ovary syndrome and metabolic syndrome, but possibly ineffective for anxiety and depression.

L-theanine is possibly effective for cognitive function but has insufficient evidence for Alzheimer's disease and generalized anxiety. In short, this product's main ingredients lack strong proof of benefit for most conditions.

The evidence, ingredient by ingredient Gamma-aminobutyric Acid (gaba) Taurine Inositol Theanine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Orally, all four ingredients are generally well tolerated in the short term, though long-term safety data is sparse. The most common side effects are drowsiness, nausea, diarrhea, gas, and stomach upset — a small number of people may experience headaches or minor throat burning.

Taurine occasionally causes constipation or heartburn, and there's a rare risk of allergic reaction in people sensitive to sulfur-containing compounds. One case report linked taurine to mood disturbances in the context of an energy drink, but it's unclear if taurine alone was responsible.

Regarding pregnancy, taurine is rated likely safe; inositol and L-theanine have insufficient safety data and should be avoided unless your doctor supervises. GABA has no pregnancy or breastfeeding safety rating on file — there isn't enough data either way.

For breastfeeding, taurine is cautioned (though it occurs naturally in breast milk, supplement doses are unstudied), and L-theanine should be avoided. Talk with your pharmacist or doctor before using this product if you're pregnant or nursing.

Side effects, ingredient by ingredient Gamma-aminobutyric Acid (gaba) Taurine Inositol Theanine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 4 of the 4 matched ingredients can interact with medications — Inositol, Gamma-aminobutyric Acid (gaba), Taurine, Theanine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; lithium.
  • For scale: 651 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check your medications list for blood pressure drugs (antihypertensives), diabetes medicines, sedating drugs (CNS depressants), lithium, and serotonergic drugs like antidepressants. The blood pressure and diabetes interactions are Moderate severity; sedative and serotonin interactions are Minor.

If you're on any of these, use the medication checker on this page.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product is best for someone looking to explore natural relaxation support who's not on blood pressure, diabetes, or lithium medications. If you take antihypertensives, diabetes drugs, sedatives, or lithium, you'll need to check with your pharmacist first — the interactions are real.

Pregnant or breastfeeding? Talk to your doctor; the safety data is thin.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Chewable GABA, straight from the product label.

Brand NOW
Barcode (UPC) 733739000828
Net contents 90 Chewable(s)
Market status On market
Date entered into DSLD Feb 25, 2021
DSLD ID 244353
Product type Non-nutrient/non-botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Chewable GABA by NOW, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Chewable Tablet(s)
Maximum serving Sizes:
2 Chewable Tablet(s)
Servings per container
45
UPC/BARCODE
733739000828
IngredientAmount% DV
Calories15 Calorie(s)--
Total Carbohydrates4 Gram(s)1%
GABA500 mg--
Taurine100 mg--
Inositol80 mg--
L-Theanine20 mg--
Added Sugars0 Gram(s)--
Total Sugars0 Gram(s)--
Sugar Alcohols3 Gram(s)--

Other ingredients: Hydroxypropyl Cellulose, Microcrystalline Cellulose, Natural Orange Juice Powder, Natural Flavors, Stearic Acid, Citric Acid, Xanthan Gum, Beta-Carotene, Magnesium Stearate, Silicon Dioxide, Ascorbyl Palmitate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Usage: Take 2 chewable tablets 1 to 2 times daily as needed, preferably with juice or water on an empty stomach.

Formula

GABA (Gamma Aminobutyric Acid) is a non-protein amino acid that functions as a neurotransmitter in the human brain. GABA is naturally produced in the body and its presence within the central nervous system may help promote relaxation and ease nervous tension.

Delicious orange flavor NOW Chewable GABA combines this naturally occurring neurotransmitter with the relaxing amino acids Taurine and Theanine for their complementary functions.

Sweetened with Xylitol

Plus Taurine, Inositol and Theanine

Triangle K (Kosher)

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

Not manufactured with wheat, gluten, milk, egg, fish, shellfish or tree nut ingredients.

Neurotransmitter Support Promotes Relaxation Eases Nervous Tension

Vegetarian/Vegan

Precautions

Not manufactured with wheat, gluten, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Caution: For adults only.

Consult physician if pregnant/nursing, taking medication, or have a medical condition.

Keep out of reach of children.

Contains Xylitol, which is harmful to pets.

Contains soy (oil).

General Statements

Natural color variation may occur in this product.

Amino Acids Family owned since 1968.

Storage

Store in a cool, dry place after opening.

FDA Statement of Identity

A Dietary Supplement

Seals/Symbols

Triangle K (Kosher)

GMP Quality Assured

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Chewable GABA by NOW label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Chewable GABA label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Chewable GABA by NOW

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Chewable Tablet(s) Dosage formTablet Or Pill Servings per container45 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

GABA

Interacts with
419 drugs
500 mg per serving

GABA is a calming chemical messenger (neurotransmitter) that your body makes on its own, and it is sold as a supplement for stress, anxiety, and sleep...

GABA monograph & interactions

Taurine

Interacts with
173 drugs
100 mg per serving

Taurine is an amino acid your body makes naturally and that you also get from animal foods. It is widely used in energy drinks and sports supplements,...

Taurine monograph & interactions

Inositol

Interacts with
86 drugs
80 mg per serving

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, m...

Inositol monograph & interactions

L-Theanine

Interacts with
565 drugs
20 mg per serving

Theanine (usually L-theanine) is an amino acid found naturally in tea leaves that many people take to feel calmer and less stressed without strong dro...

L-Theanine monograph & interactions

Other (inactive) ingredients: Hydroxypropyl Cellulose, Microcrystalline Cellulose, Natural Orange Juice Powder, Natural Flavors, Stearic Acid, Citric Acid, Xanthan Gum, Beta-Carotene, Magnesium Stearate, Silicon Dioxide, Ascorbyl Palmitate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Chewable GABA by NOW Drug Interactions

Want to check YOUR meds against Chewable GABA?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
651Drugs
259 Moderate 392 Minor

Ingredients driving the most interactions

L-Theanine 565
GABA 419
Taurine 173
Inositol 86

Individual Drug Interactions

The ingredients in Chewable GABA interact with 651 drugs. Click any drug to see the details.

4 of the 4 ingredients in Chewable GABA interact with drugs. Each result below shows which ingredient is responsible. L-Theanine GABA Taurine Inositol

Each ingredient & the kinds of drugs it affects

For each ingredient in Chewable GABA with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Theanine3 drug types · 565 drugs

Antihypertensive Drugs

Theanine might lower blood pressure, potentiating the effects of antihypertensive drugs.
Animal research shows that theanine can lower blood pressure in spontaneously hypertensive animals. Theoretically, concomitant use of theanine and antihypertensive drugs might potentiate the antihypertensive activity.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, theanine might have additive sedative effects when used in conjunction with CNS depressants. However, it is unclear if this concern is clinically relevant.
Theoretically, theanine may compete with glutamate and/or increase plasma gamma-aminobutyric acid (GABA) levels, which could cause CNS depression. In one clinical study, some subjects taking oral theanine reported drowsiness.

Likelihood Unlikely Evidence D
Serotonergic Drugs

Clinical studies regarding the effects of L-theanine on serotonin levels are conflicting. Some studies suggest it can increase serotonin levels in the brain while others report that it may decrease them. Nevertheless, there have been no reports of l-theanine being a causative agent in serotonergic-related side effects or serotonin syndrome.

Likelihood Unlikely Evidence C
L-Theanine full monograph & interactions

GABA2 drug types · 419 drugs

Antihypertensive Drugs

Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Some clinical research shows that GABA can decrease blood pressure in patients with hypertension.

Likelihood Possible Evidence B
Cns Depressants

Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants. However, it is unclear if this concern is clinically relevant.
Endogenous GABA has well-established relaxant effects and GABA(A) receptors have an established physiological role in sleep. However, the effects of GABA supplements are unclear, as it is unknown whether exogenous GABA crosses the blood-brain barrier. Although there have been limited reports of drowsiness or tiredness with GABA supplements, these effects have not been widely reported in clinical studies. Additionally, intravenous GABA 0.1-1 mg/kg has been shown to induce anxiety in a dose-dependent manner.

Likelihood Unlikely Evidence D
GABA full monograph & interactions

Taurine2 drug types · 173 drugs

Antihypertensive Drugs

Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Some clinical evidence suggests that taurine can reduce both systolic and diastolic blood pressure.

Likelihood Probable Evidence D
Lithium

Theoretically, taurine might reduce excretion and increase plasma levels of lithium.
Taurine is thought to have diuretic properties, which might reduce the excretion of lithium.

Likelihood Probable Evidence D
Taurine full monograph & interactions

Inositol1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that inositol lowers blood glucose levels and glycated hemoglobin (HbA1c) levels in patients with diabetes.

Likelihood Possible Evidence A
Inositol full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Chewable GABA, from the product label.

NOW

See all NOW products
Name
NOW Foods
Street Address
395 S. Glen Ellyn Rd.
City
Bloomingdale
State
IL
ZipCode
60108
Web Address
www.nowfoods.com
Pharmacist Counseling Corner

Chewable GABA by NOW: Common Questions

Does Chewable GABA by NOW interact with any medications?
Yes. Based on its ingredients, Chewable GABA has a known interaction with 651 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Chewable GABA contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What does each ingredient in this chewable do?
GABA is a relaxing brain chemical. Taurine supports heart and overall metabolic health. Inositol helps regulate blood sugar and cellular function. L-theanine, from tea, promotes calm focus. Together they're meant to support relaxation, though proof is limited for most uses.
Can I take this if I'm on a blood pressure medication?
Not without checking first. GABA, taurine, and L-theanine can all lower blood pressure, so taking them with your medication could drop your pressure too far. Talk to your pharmacist or doctor — they'll let you know if it's safe for your specific drug and dose.
What are the most common side effects?
Drowsiness, nausea, diarrhea, gas, and upset stomach are the main ones people report. A few experience headaches or throat irritation. Most side effects are mild, but long-term safety hasn't been thoroughly studied.
Is this safe during pregnancy or while breastfeeding?
Taurine is rated likely safe in pregnancy. For inositol and L-theanine, there isn't enough data — they should be avoided unless your doctor supervises. GABA has no safety rating on file. For breastfeeding, avoid L-theanine and use taurine only with caution. Talk to your doctor or pharmacist before taking any of these while pregnant or nursing.
Does this actually help with anxiety?
The evidence isn't clear. GABA and L-theanine both have insufficient reliable evidence to rate for anxiety, meaning we don't have enough solid studies yet. Inositol is possibly ineffective for anxiety. If you're hoping this will treat anxiety, talk to your doctor — you may need something with stronger proof.
Can I take this with my antidepressant?
L-theanine has a minor documented interaction with serotonergic drugs like antidepressants, though no cases of serotonin syndrome have been reported. Still, it's worth a quick check with your pharmacist to be sure it's okay with your specific medication.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Chewable GABA is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Chewable GABA label
Go deeper

The Full Monographs Behind Chewable GABA’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Gamma-aminobutyric Acid (gaba)

Interacts with 419 drugs

GABA is a calming chemical messenger (neurotransmitter) that your body makes on its own, and it is sold as a supplement for stress, anxiety, and sleep. The science behind oral GABA supplemen...

Read the full Gamma-aminobutyric Acid (gaba) monograph → Herb & supplement monograph

Taurine

Interacts with 173 drugs

Taurine is an amino acid your body makes naturally and that you also get from animal foods. It is widely used in energy drinks and sports supplements, and short-term use appears generally sa...

Read the full Taurine monograph → Herb & supplement monograph

Inositol

Interacts with 86 drugs

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, mood, and metabolic concerns. The stronge...

Read the full Inositol monograph → Herb & supplement monograph

Theanine

Interacts with 565 drugs

Theanine (usually L-theanine) is an amino acid found naturally in tea leaves that many people take to feel calmer and less stressed without strong drowsiness. Early research suggests it may...

Read the full Theanine monograph →
Sources

Sources & How We Checked

Chewable GABA's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 53 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Gamma-aminobutyric Acid (gaba) 12 references
  1. Cavagnini F, Invitti C, Pinto M, et al. Effect of acute and repeated administration of gamma aminobutyric acid (GABA) on growth hormone and prolactin secretion in man. Acta Endocrinol (Copenh) 1980;93:149-54.
  2. Nurnberger JI Jr, Berrettini WH, Simmons-Alling S, et al. Intravenous GABA administration is anxiogenic in man. Psychiatry Res 1986;19:113-7. PubMed
  3. Gershman RN, Vasilenko MA, Iliushina GG, et al. [Gammalon in the rehabilitation in infantile cerebral palsy]. Pediatr.Akus.Ginekol. 1977;(6):26-7.
  4. Loeb C, Benassi E, Bo, GP, et al. Preliminary evaluation of the effect of GABA and phosphatidylserine in epileptic patients. Epilepsy Res. 1987;1:209-12 . PubMed
  5. Inoue K, Shirai T, Ochiai H, et al. Blood-pressure-lowering effect of a novel fermented milk containing gamma-aminobutyric acid (GABA) in mild hypertensives. Eur J Clin Nutr 2003;57:490-95.
  6. ELLIOTT, K. A. and JASPER, H. H. Gammaaminobutyric acid. Physiol Rev. 1959;39(2):383-406.
  7. Winsky-Sommerer, R. Role of GABAA receptors in the physiology and pharmacology of sleep. Eur.J.Neurosci. 2009;29(9):1779-1794.
  8. Meldrum, B. S. GABAergic mechanisms in the pathogenesis and treatment of epilepsy. Br.J.Clin.Pharmacol. 1989;27 Suppl 1:3S-11S. PubMed
  9. Loeb, C., Marinari, U. M., Benassi, E., Besio, G., Cottalasso, D., Cupello, A., Maffini, M., Mainardi, P., Pronzato, M. A., and Scotto, P. A. Phosphatidylserine increases in vivo the synaptosomal uptake of exogenous GABA in rats. Exp.Neurol. 1988;99(2):4 PubMed
  10. Melis, G. B., Paoletti, A. M., Mais, V., and Fioretti, P. Interference of dopamine infusion on gamma-amino butyric acid (GABA)-stimulated prolactin increase. J.Endocrinol.Invest 1980;3(4):445-448.
  11. Boonstra E, de Kleijn R, Colzato LS, Alkemade A, Forstmann BU, Nieuwenhuis S. Neurotransmitters as food supplements: the effects of GABA on brain and behavior. Front Psychol. 2015 Oct 6;6:1520. doi: 10.3389/fpsyg.2015.01520. eCollection 2015. PubMed
  12. de Bie TH, Witkamp RF, Balvers MG, Jongsma MA. Effects of ?-aminobutyric acid supplementation on glucose control in adults with prediabetes: A double-blind, randomized, placebo-controlled trial. Am J Clin Nutr 2023;118(3):708-719. PubMed

See these in context on the Gamma-aminobutyric Acid (gaba) monograph →

Taurine 21 references
  1. Ahmad S, Robertson HT, Golper TA, et al. Multicenter trial of L-carnitine in maintenance hemodialysis patients. II. Clinical and biochemical effects. Kidney Int 1990;38:912-8. PubMed
  2. Machado-Vieira R, Viale CI, Kapczinski F. Mania associated with an energy drink: the possible role of caffeine, taurine, and inositol. Can J Psychiatry 2001;46:454-5. PubMed
  3. Obermann M, Schorn CF, Mummel P, et al. Taurine induced toxic encephalopathy? Clin Neurol Neurosurg 2006;108:812-3. PubMed
  4. Bichler, A., Swenson, A., and Harris, M. A. A combination of caffeine and taurine has no effect on short term memory but induces changes in heart rate and mean arterial blood pressure. Amino Acids 2006;31(4):471-476. PubMed
  5. Iyadurai, S. J. and Chung, S. S. New-onset seizures in adults: possible association with consumption of popular energy drinks. Epilepsy Behav 2007;10(3):504-508. PubMed
  6. Berger, A. J. and Alford, K. Cardiac arrest in a young man following excess consumption of caffeinated "energy drinks". Med J Aust. 1-5-2009;190(1):41-43. PubMed
  7. Worthley, M. I., Prabhu, A., De, Sciscio P., Schultz, C., Sanders, P., and Willoughby, S. R. Detrimental effects of energy drink consumption on platelet and endothelial function. Am J Med 2010;123(2):184-187. PubMed
  8. Morchon, Simon D. and Perez Castrillon, J. L. [Hypoglycemia by intake of taurine]. Rev.Clin Esp. 2010;210(1):49.
  9. Livshits, Z., Hoffman, R. S., Hymes, K. B., and Nelson, L. S. If vitamins could kill: massive hemolysis following naturopathic vitamin infusion. J Med Toxicol. 2011;7(3):224-226. PubMed
  10. Schoffl, I., Kothmann, J. F., Schoffl, V., Rupprecht, H. D., and Rupprecht, T. "Vodka energy": too much for the adolescent nephron? Pediatrics 2011;128(1):e227-e231. PubMed
  11. Calabro, R. S., Italiano, D., Gervasi, G., and Bramanti, P. Single tonic-clonic seizure after energy drink abuse. Epilepsy Behav 2012;23(3):384-385. PubMed
  12. Fujita, T., Ando, K., Noda, H., Ito, Y., and Sato, Y. Effects of increased adrenomedullary activity and taurine in young patients with borderline hypertension. Circulation 1987;75(3):525-532. PubMed
  13. Darling, P. B., Lepage, G., Leroy, C., Masson, P., and Roy, C. C. Effect of taurine supplements on fat absorption in cystic fibrosis. Pediatr Res 1985;19(6):578-582. PubMed
  14. Fukuyama, Y. and Ochiai, Y. Therapeutic trial by taurine for intractable childhood epilepsies. Brain Dev. 1982;4(1):63-69. PubMed
  15. Franconi, F., Bennardini, F., Mattana, A., Miceli, M., Ciuti, M., Mian, M., Gironi, A., Anichini, R., and Seghieri, G. Plasma and platelet taurine are reduced in subjects with insulin-dependent diabetes mellitus: effects of taurine supplementation. Am.J. DOI
  16. Stohs SJ, Miller M. A case study involving allergic reactions to sulfur-containing compounds including, sulfite, taurine, acesulfame potassium and sulfonamides. Food Chem Toxicol. 2014 Jan;63:240-3. PubMed
  17. Sun Q, Wang B, Li Y, Sun F, et al. Taurine supplementation lowers blood pressure and improves vascular function in prehypertension: randomized, double-blind, placebo-controlled study. Hypertension 2016 Mar;67(3):541-9. PubMed
  18. Jang ES, Hwang SH, Kim JW, Jeong SH. Effectiveness of 4-week oral taurine treatment for muscle cramps in patients with liver cirrhosis: a single-arm pilot study. Yonsei Med J 2021;62(1):21-8. PubMed
  19. Guan L, Miao P. The effects of taurine supplementation on obesity, blood pressure and lipid profile: A meta-analysis of randomized controlled trials. Eur J Pharmacol 2020;885:173533. PubMed
  20. Higgins JP, Liras GN, Liras IN, et al. Energy Drink Effects on Hemodynamics and Endothelial Function in Young Adults. Cardiology. 2021;146(2):258-262. PubMed
  21. Pallangyo P, Bhalia SV, Komba M, et al. Acute Myocardial Infarction Following the Consumption of Energy Drink in a 28-Year-Old Male: A Case Report. J Investig Med High Impact Case Rep. 2023 Jan-Dec;11:23247096231168811. PubMed

See these in context on the Taurine monograph →

Inositol 14 references
  1. Palatnik A, Frolov K, Fux M, Benjamin J. Double-blind, controlled, crossover trial of inositol versus fluvoxamine for the treatment of panic disorder. J Clin Psychopharmacol 2001;21:335-9.. PubMed
  2. Allan SJ, Kavanagh GM, Herd RM, Savin JA. The effect of inositol supplements on the psoriasis of patients taking lithium: a randomized, placebo-controlled trial. Br J Dermatol 2004;150:966-9. PubMed
  3. Machado-Vieira R, Viale CI, Kapczinski F. Mania associated with an energy drink: the possible role of caffeine, taurine, and inositol. Can J Psychiatry 2001;46:454-5. PubMed
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See these in context on the Inositol monograph →

Theanine 6 references
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See these in context on the Theanine monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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