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Dietary supplement

Chlorella Ingredients & Drug Interactions

by Hawaii Pharm

Chlorella label
See full label image
Liquid Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Chlorella against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Chlorella is a dietary supplement by Hawaii Pharm with 1 active ingredient. Its ingredients are commonly taken for general nutrition and 'detox' support, immune support, liver and kidney support.Based on those ingredients, 337 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are wild harvested Chlorella extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Chlorella by Hawaii Pharm

Ask about any prescription or over-the-counter medication and we check it for interactions with Chlorella by Hawaii Pharm — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Chlorella by Hawaii Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.

This product contains one active ingredient: wild harvested chlorella extract. Chlorella is a type of algae used in supplements for various health purposes.

The liquid also contains vegetable palm glycerin and Hawaiian artesian water as inactive ingredients.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Chlorella's overall clinical evidence instead.

Moderate

Some clinical evidence supports Chlorella for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Pregnancy-related iron deficiency — rated "Possibly Effective" (Natural Medicines).

The evidence for chlorella varies by use. It's possibly effective for pregnancy-related iron deficiency.

For brain tumors, depression, nonalcoholic fatty liver disease, and fatigue, the evidence we hold is insufficient — we don't have enough reliable data to rate whether it works for these conditions. Talk with your doctor if you're considering it for any of these.

The evidence, ingredient by ingredient Chlorella

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Chlorella is generally well tolerated in the short term, but there's an important catch: product quality and purity vary widely, and long-term safety data aren't well established. Common side effects include allergic reactions, stomach cramping, constipation, diarrhea, fatigue, gas, nausea, photosensitivity, and discolored stools — many of these are mild and temporary, especially in the first two weeks.

Rarely, serious allergic reactions including anaphylaxis have been reported. Because safety data are limited, don't use this unless your doctor approves.

Side effects, ingredient by ingredient Chlorella

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Chlorella.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 337 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist if you take warfarin (Coumadin) — chlorella can reduce its effectiveness. Also flag any photosensitizing drugs (medications that make your skin sun-sensitive) before starting this product.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

If you take warfarin or photosensitizing medications, you need to talk with your pharmacist before starting chlorella. Even if you don't take those drugs, check your exact medications with the tool on this page.

Chlorella may help with pregnancy-related iron deficiency, but evidence for other uses is unclear.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Chlorella, straight from the product label.

Brand Hawaii Pharm
Barcode (UPC) 6339127905030
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Oct 23, 2020
DSLD ID 238338
Product type Non-nutrient/non-botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Chlorella by Hawaii Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
20 Drop(s)
Maximum serving Sizes:
30 Drop(s)
UPC/BARCODE
6339127905030
IngredientAmount% DV
wild harvested Chlorella extract0 NP--

Other ingredients: Vegetable Palm Glycerin, crystal clear artesian Hawaiian Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Hawaii Pharm Non-Alcohol Herbal Extract Highest quality since 2008

Made with Aloha!

Formulation

Contains no gluten, artificial colors, pesticides, preservatives, heavy metals. Non GMO.

Super concentrated liquid herbal extract Dry herb/menstruum ratio: 1:3

Contains no alcohol

Description: We meticulously produced this extract according to precise standards where each herbs are individually extracted according to their distinct characteristic to ensure a broad spectrum of therapeutic plant compounds. We use a classic maceration extraction method in combination with ultrasonic extraction, so that the vitamins, minerals, alkaloids, flavonoids and other active constituents of the herbs are maintained.

Manufactured in an FDA registered facility. Ultra Sonic

Non GMO Gluten free

Made in USA, Hawaii

Suggested/Recommended/Usage/Directions

Directions for use: Shake well before using. Take about 20-30 drops in juice, water, tea or as desired up to four times per day.

Precautions

Warnings: Keep out of the reach of children.

Not to be used during pregnancy. Consult a physician before using if nursing or taking any medications.

Do not use if you are allergic to any ingredients.

Do not use if seal is broken or missing.

Storage

Refrigerate after opening.

Formula

(Chlorella vulgaris)

FDA Statement of Identity

Herbal Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

FDA Registered Facility Made in United States of America USA

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Chlorella by Hawaii Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Chlorella label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Chlorella by Hawaii Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size20 Drop(s) Dosage formLiquid Amounts shown are per serving.

Wild harvested Chlorella extract

Interacts with
337 drugs
0 NP per serving

Chlorella is a nutrient-rich freshwater green algae taken as a supplement for general wellness, immune support, and 'detox.' Some small studies sugges...

Wild harvested Chlorella extract monograph & interactions

Other (inactive) ingredients: Vegetable Palm Glycerin, Crystal clear artesian Hawaiian Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Chlorella by Hawaii Pharm Drug Interactions

Want to check YOUR meds against Chlorella?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
337Drugs
337 Moderate

Ingredients driving the most interactions

wild harvested Chlorella extract 337

Individual Drug Interactions

The ingredients in Chlorella interact with 337 drugs. Click any drug to see the details.

1 of the 1 ingredient in Chlorella interact with drugs. Each result below shows which ingredient is responsible. wild harvested Chlorella extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Chlorella with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

wild harvested Chlorella extract2 drug types · 337 drugs

Photosensitizing Drugs

Theoretically, chlorella might have additive effects with photosensitizing drugs.
Chlorella has been reported to cause photosensitization. In five case reports, patients who had ingested chlorella exhibited swelling followed by erythematopurpuric lesions on sun-exposed areas of the body. Theoretically, concomitant use with photosensitizing drugs may exacerbate effects.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, chlorella might reduce the clinical effects of warfarin.
Chlorella contains significant amounts of vitamin K. There is at least one case report of warfarin therapy becoming sub-therapeutic after initiation of chlorella supplements.

Likelihood Possible Evidence D
wild harvested Chlorella extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Chlorella, from the product label.

Hawaii Pharm

See all Hawaii Pharm products
Name
Hawaii Pharm LLC
City
Honolulu
State
HI
ZipCode
96815
Pharmacist Counseling Corner

Chlorella by Hawaii Pharm: Common Questions

Does Chlorella by Hawaii Pharm interact with any medications?
Yes. Based on its ingredients, Chlorella has a known interaction with 337 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Chlorella contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is chlorella safe during pregnancy?
Chlorella is rated possibly safe in pregnancy based on the data we hold. That said, long-term safety isn't well established, so talk with your doctor or midwife before starting it while pregnant.
What are the most common side effects?
The most common ones are stomach cramping, diarrhea, gas, nausea, and constipation — especially in the first two weeks. Some people report fatigue, allergic reactions, or darkened stools. Most are mild and temporary.
Can chlorella help with iron deficiency in pregnancy?
Yes, chlorella is possibly effective for pregnancy-related iron deficiency based on our data. If you're pregnant and low on iron, ask your doctor whether it might fit your care plan.
Why does the label say to avoid it unless my doctor approves?
Because safety data for long-term use aren't well established. This product can vary in quality and purity depending on where it comes from, so it's wise to have professional oversight before starting it.
Is this the same as taking chlorella tablets?
This is a liquid extract, whereas many chlorella supplements are tablets or capsules. The form doesn't change the active ingredient, but liquid absorption can differ from tablets. Your pharmacist can tell you more about what works best for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Chlorella is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Chlorella label
Go deeper

The Full Monographs Behind Chlorella’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Chlorella

Interacts with 337 drugs

Chlorella is a nutrient-rich freshwater green algae taken as a supplement for general wellness, immune support, and 'detox.' Some small studies suggest possible benefits for cholesterol, blo...

Read the full Chlorella monograph →
Sources

Sources & How We Checked

Chlorella's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 13 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Chlorella 13 references
  1. Peirce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York, NY: William Morrow and Co., 1999.
  2. Ng TP, Tan WC, Lee YK. Occupational asthma in a pharmacist induced by chlorella, a unicellular algae preparation. Resp Med 1994;88:555-7. PubMed
  3. Jitsukawa K, Suizu R, Hidano A. Chlorella photosensitization. New phytophotodermatosis. Int J Dermatol 1984;23:263-8. PubMed
  4. Merchant RE, Carmack CA, Wise CM. Nutritional supplementation with Chlorella pyrenoidosa for patients with fibromyalgia syndrome: a pilot study. Phytother Res 2000;14:167-73.
  5. Merchant RE, Rice CD, Young HF. Dietary Chlorella pyrenoidosa for patients with malignant glioma: effects on immunocompetence, quality of life, and survival. Phytother Res 1990;4:220-31.
  6. Halperin SA, Smith B, Nolan C, et al. Safety and immunoenhancing effect of a Chlorella-derived dietary supplement in healthy adults undergoing influenza vaccination: randomized, double-blind, placebo-controlled trial. CMAJ 2003;169:111-7..
  7. Ohtake, T., Negishi, K., Okamoto, K., Oka, M., Maesato, K., Moriya, H., and Kobayashi, S. Manganese-induced Parkinsonism in a patient undergoing maintenance hemodialysis. Am J Kidney Dis 2005;46(4):749-753. PubMed
  8. Ng, T. P., Tan, W. C., and Lee, Y. K. Occupational asthma in a pharmacist induced by Chlorella, a unicellular algae preparation. Respir.Med. 1994;88(7):555-557. PubMed
  9. Ohkawa, S., Yoneda, Y., Ohsumi, Y., and Tabuchi, M. [Warfarin therapy and chlorella]. Rinsho Shinkeigaku 1995;35(7):806-807.
  10. Azocar J, Diaz A. Efficacy and safety of chlorella supplementation in adults with chronic hepatitis C virus infection. World J Gastroenterol 2013;19(7):1085-90. PubMed
  11. Panahi Y, Badeli R, Karami GR, Badeli Z, Sahebkar A. A randomized controlled trial of 6-week Chlorella vulgaris supplementation in patients with major depressive disorder. Complement Ther Med 2015;23(4):598-602. PubMed
  12. Nakano S, Takekoshi H, Nakano M. Chlorella pyrenoidosa supplementation reduces the risk of anemia, proteinuria and edema in pregnant women. Plant Foods Hum Nutr 2010;65(1):25-30. PubMed
  13. Yavasoglu I, Turgutkaya A, Bolaman Z. Chlorella-induced thrombocytopenia. Sao Paulo Med J 2018;136(6):602-3. PubMed

See these in context on the Chlorella monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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