Chlorophyll 100 mg Ingredients & Drug Interactions
by NOW
What is this page for?
First and foremost: checking Chlorophyll 100 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Chlorophyll 100 mg is a dietary supplement by NOW with 2 active ingredients. Its ingredients are commonly taken for high cholesterol, digestive complaints, menopausal symptoms.Based on those ingredients, 698 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Alfalfa, Powder, Sodium Copper Chlorophyllin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Chlorophyll 100 mg by NOW
Ask about any prescription or over-the-counter medication and we check it for interactions with Chlorophyll 100 mg by NOW — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Chlorophyll 100 mg by NOW
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains 2 active ingredients: alfalfa powder and sodium copper chlorophyllin. Alfalfa is a plant commonly used in supplements; sodium copper chlorophyllin is a water-soluble form of chlorophyll, the pigment that makes plants green.
Both come from plant sources. The capsule also contains hypromellose and stearic acid as inactive ingredients (binders and capsule material).
Does it work?
Strong evidence
The evidence on alfalfa's effectiveness for the conditions it's promoted for — blood sugar control, digestive upset, cholesterol, and menopausal symptoms — is insufficient to rate. For sodium copper chlorophyllin, the data shows it is likely effective for cystic fibrosis and possibly effective for kidney damage caused by the drug amphotericin B.
Beyond those two uses, the evidence is insufficient to rate or not yet established in the data we hold.
How safe is it?
Well-documented data
Alfalfa leaf is generally well tolerated in small amounts, but most common side effects from supplements and case reports include abdominal discomfort, diarrhea, flatulence, and intestinal gas — especially in the first week of use. Rarely, chronic alfalfa use has been linked to a lupus-like syndrome, and dermatitis (skin inflammation) has occurred with large doses.
Sodium is essential in normal dietary amounts, but excess sodium from supplements is linked to high blood pressure, heart strain, and kidney disease. For pregnancy and breastfeeding: alfalfa is rated possibly unsafe due to its estrogen-like activity, and not enough safety data exists for breastfeeding — talk with your doctor or pharmacist.
Sodium is likely safe in pregnancy at usual dietary levels but possibly unsafe at higher intakes or supplement doses.
Meds to double-check
Major interaction found
Before taking this product, check with your pharmacist if you take warfarin or other blood thinners (Major interaction with alfalfa), or any of these Moderate-severity drug types: blood pressure medications, corticosteroids, lithium, birth control pills, hormone therapy, diabetes medications, immunosuppressants, or photosensitizing drugs. Also check if you take didanosine, sodium phosphates, tolvaptan, or any other sodium-containing medications.
The bottom line
Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Major medication interactions have been identified, and safety information is well characterized.
This product is worth considering only if you're using it for cystic fibrosis or amphotericin B kidney toxicity — and only under medical supervision. If you take any medication, especially blood thinners, blood pressure drugs, lithium, or birth control, talk with your pharmacist before starting.
The sodium content and alfalfa's hormone-like effects add to the caution list.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Chlorophyll 100 mg, straight from the product label.
| Brand | NOW |
|---|---|
| Barcode (UPC) | 733739026453 |
| Net contents | 90 Veg Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jul 25, 2024 |
| DSLD ID | 313809 |
| Product type | Botanical With Nutrients |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Kosher, Halal, Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Chlorophyll 100 mg by NOW, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Alfalfa, Powder | 250 mg | -- |
| Sodium Copper Chlorophyllin | 100 mg | -- |
Other ingredients: Hypromellose, Stearic Acid
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Usage: Take 1 capsule 1 to 3 times daily.
Formula
Chlorophyll is green pigment naturally produced by plants and algae and gives them their characteristic green color. Chlorophyll is critical for photosynthesis, the process by which sunlight is converted into chemical energy. Chlorophyll can function as a free radical neutralizer, may help to support the body's detoxification processes and has been traditionally used as an internal deodorizer.
This water-soluble extract is in the form of sodium copper chlorophyllin.
Chlorophyll 100 mg with alfalfa powder
Triangle K (Kosher)
Crescent H (Halal)
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Precautions
Caution: For adults only. Keep out of reach of children.
Consult physician if pregnant/nursing, taking medication (this product contains Alfalfa), or have a medical condition.
Keep out of reach of children.
When taken orally, chlorophyll may cause diarrhea or green discoloration of urine or feces.
Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.
Formulation
Natural color variation may occur in this product.
Super green Free radical scavenger
Non-GMO
Made and quality tested in the USA with globally sourced ingredients.
Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients.
FDA Statement of Identity
A Dietary Supplement
Seals/Symbols
Triangle K (Kosher)
Crescent H (Halal) GMP Quality Assured
General Statements
Botanicals/Herbs Family owned since 1968.
Storage
Store in a cool, dry place after opening.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Chlorophyll 100 mg by NOW label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Chlorophyll 100 mg by NOW
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Veg Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Alfalfa, Powder
Interacts with583 drugs
Alfalfa is a nutrient-rich legume that people use for high cholesterol, menopause symptoms, and general wellness, but solid human evidence for most of...
Alfalfa, Powder monograph & interactionsSodium Copper Chlorophyllin
Interacts with205 drugs
Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...
Sodium Copper Chlorophyllin monograph & interactionsOther (inactive) ingredients: Hypromellose, Stearic Acid. These complete the product’s ingredient list but are not active constituents.
Chlorophyll 100 mg by NOW Drug Interactions
HelloPharmacist Interaction Report
NOW's Chlorophyll 100 mg contains alfalfa and sodium copper chlorophyllin, and together these ingredients interact with a substantial number of medications.
The most serious interaction is between alfalfa and warfarin (Coumadin), a blood thinner (anticoagulant). Alfalfa is high in vitamin K, which can reduce warfarin's ability to prevent blood clots — a Major-severity concern.
Read the full breakdown — every affected drug type, severity by severity
Alfalfa also carries Moderate-severity interactions with photosensitizing drugs (drugs that increase skin sensitivity to sunlight), birth control pills, hormone replacement therapy, immunosuppressants (drugs that suppress the immune system), and diabetes medications. The sodium in this product interacts with blood pressure medications, corticosteroids, lithium, didanosine, sodium phosphates, tolvaptan, and other sodium-containing drugs — all Moderate severity, mainly because excess sodium can raise blood pressure or cause dangerously high sodium levels in your blood.
Altogether, these interactions span 690 individual medications. Because the ingredient list is short but the interaction footprint is large, it's especially important to run your exact medications through the checker below before starting this supplement.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Chlorophyll 100 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Chlorophyll 100 mg interact with 698 drugs. Click any drug to see the details.
2 of the 2 ingredients in Chlorophyll 100 mg interact with drugs. Each result below shows which ingredient is responsible. Alfalfa, Powder Sodium Copper Chlorophyllin
AdalimumabHumira
How Adalimumab interacts with Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Alfalfa, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, alfalfa might decrease the efficacy of immunosuppressive therapy.
Read the full Alfalfa, Powder + Adalimumab interactionAdalimumab-adazHyrimoz
How Adalimumab-adaz interacts with Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Alfalfa, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, alfalfa might decrease the efficacy of immunosuppressive therapy.
Read the full Alfalfa, Powder + Adalimumab-adaz interactionAdalimumab-adbmCyltezo
How Adalimumab-adbm interacts with Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Alfalfa, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, alfalfa might decrease the efficacy of immunosuppressive therapy.
Read the full Alfalfa, Powder + Adalimumab-adbm interactionAdalimumab-afzbAbrilada
How Adalimumab-afzb interacts with Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Alfalfa, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, alfalfa might decrease the efficacy of immunosuppressive therapy.
Read the full Alfalfa, Powder + Adalimumab-afzb interactionAdalimumab-attoAmjevita
How Adalimumab-atto interacts with Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Alfalfa, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, alfalfa might decrease the efficacy of immunosuppressive therapy.
Read the full Alfalfa, Powder + Adalimumab-atto interactionAdalimumab-bwwdHadlima
How Adalimumab-bwwd interacts with Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Alfalfa, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, alfalfa might decrease the efficacy of immunosuppressive therapy.
Read the full Alfalfa, Powder + Adalimumab-bwwd interactionAdalimumab-fkjpHulio
How Adalimumab-fkjp interacts with Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Alfalfa, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, alfalfa might decrease the efficacy of immunosuppressive therapy.
Read the full Alfalfa, Powder + Adalimumab-fkjp interactionAlbiglutideTanzeum
How Albiglutide interacts with Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Alfalfa, PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, alfalfa might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Alfalfa, Powder + Albiglutide interactionAlectinib HydrochlorideAlecensa
How Alectinib Hydrochloride interacts with Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Alfalfa, PowderPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of alfalfa with photosensitizing drugs might have additive effects.
Read the full Alfalfa, Powder + Alectinib Hydrochloride interactionAlefaceptAmevive
How Alefacept interacts with Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Alfalfa, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, alfalfa might decrease the efficacy of immunosuppressive therapy.
Read the full Alfalfa, Powder + Alefacept interactionAlemtuzumabCampath
How Alemtuzumab interacts with Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Alfalfa, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, alfalfa might decrease the efficacy of immunosuppressive therapy.
Read the full Alfalfa, Powder + Alemtuzumab interactionAliskirenTekturna
How Aliskiren interacts with Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Sodium Copper ChlorophyllinAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium Copper Chlorophyllin + Aliskiren interactionAlitretinoinPanretin
How Alitretinoin interacts with Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Alfalfa, PowderPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of alfalfa with photosensitizing drugs might have additive effects.
Read the full Alfalfa, Powder + Alitretinoin interactionAlogliptinNesina
How Alogliptin interacts with Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Alfalfa, PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, alfalfa might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Alfalfa, Powder + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Alfalfa, PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, alfalfa might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Alfalfa, Powder + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Alfalfa, PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, alfalfa might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Alfalfa, Powder + Alogliptin, Pioglitazone interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Sodium Copper ChlorophyllinAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium Copper Chlorophyllin + Ambrisentan interactionAmilorideAmilamont, Midamor
How Amiloride interacts with Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Sodium Copper ChlorophyllinAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium Copper Chlorophyllin + Amiloride interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Chlorophyll 100 mg — through 2 ingredients. Tap an ingredient for the detail:
Sodium Copper ChlorophyllinAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium Copper Chlorophyllin + Amiloride, Hydrochlorothiazide interactionAlfalfa, PowderPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of alfalfa with photosensitizing drugs might have additive effects.
Read the full Alfalfa, Powder + Amiloride, Hydrochlorothiazide interactionAminolevulinic Acid HydrochlorideAmeluz, Gleolan
How Aminolevulinic Acid Hydrochloride interacts with Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Alfalfa, PowderPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of alfalfa with photosensitizing drugs might have additive effects.
Read the full Alfalfa, Powder + Aminolevulinic Acid Hydrochloride interactionAmiodaroneCordarone, Pacerone
How Amiodarone interacts with Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Alfalfa, PowderPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of alfalfa with photosensitizing drugs might have additive effects.
Read the full Alfalfa, Powder + Amiodarone interactionAmitriptylineElavil
How Amitriptyline interacts with Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Alfalfa, PowderPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of alfalfa with photosensitizing drugs might have additive effects.
Read the full Alfalfa, Powder + Amitriptyline interactionAmitriptyline, ChlordiazepoxideLimbitrol DS
How Amitriptyline, Chlordiazepoxide interacts with Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Alfalfa, PowderPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of alfalfa with photosensitizing drugs might have additive effects.
Read the full Alfalfa, Powder + Amitriptyline, Chlordiazepoxide interactionAmitriptyline, PerphenazineEtrafon, Etrafon-A, Etrafon-Forte, Triavil
How Amitriptyline, Perphenazine interacts with Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Alfalfa, PowderPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of alfalfa with photosensitizing drugs might have additive effects.
Read the full Alfalfa, Powder + Amitriptyline, Perphenazine interactionAmlodipineNorliqva
How Amlodipine interacts with Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Sodium Copper ChlorophyllinAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium Copper Chlorophyllin + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Sodium Copper ChlorophyllinAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium Copper Chlorophyllin + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Sodium Copper ChlorophyllinAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium Copper Chlorophyllin + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Sodium Copper ChlorophyllinAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium Copper Chlorophyllin + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with Chlorophyll 100 mg — through 2 ingredients. Tap an ingredient for the detail:
Sodium Copper ChlorophyllinAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium Copper Chlorophyllin + Amlodipine Besylate, Benazepril interactionAlfalfa, PowderPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of alfalfa with photosensitizing drugs might have additive effects.
Read the full Alfalfa, Powder + Amlodipine Besylate, Benazepril interactionAmlodipine, CelecoxibConsensi
How Amlodipine, Celecoxib interacts with Chlorophyll 100 mg — through 2 ingredients. Tap an ingredient for the detail:
Alfalfa, PowderPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of alfalfa with photosensitizing drugs might have additive effects.
Read the full Alfalfa, Powder + Amlodipine, Celecoxib interactionSodium Copper ChlorophyllinAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium Copper Chlorophyllin + Amlodipine, Celecoxib interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Chlorophyll 100 mg with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Alfalfa, Powder
Warfarin (Coumadin)
Theoretically, alfalfa might reduce the anticoagulant activity of warfarin.
Alfalfa contains a large amount of vitamin K. This could theoretically interfere with the activity of warfarin.
Antidiabetes Drugs
Theoretically, alfalfa might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research suggests that alfalfa decreases blood sugar in diabetic mice. Also, in one case report, a diabetic patient experienced hypoglycemia after consuming alfalfa extract. Monitor blood glucose levels closely. Dose adjustments might be necessary.
Contraceptive Drugs
Theoretically, alfalfa might interfere with the activity of contraceptive drugs.
Alfalfa contains coumestrol, a phytoestrogen, and isoflavonoids, which have estrogenic effects.
Estrogens
Theoretically, alfalfa might interfere with hormone therapy.
Alfalfa contains coumestrol, a phytoestrogen, and isoflavonoids, which have estrogenic effects.
Immunosuppressants
Theoretically, alfalfa might decrease the efficacy of immunosuppressive therapy.
In vitro research and human case reports suggest that alfalfa may have immunostimulant effects.
Photosensitizing Drugs
Theoretically, concomitant use of alfalfa with photosensitizing drugs might have additive effects.
Animal research suggests that excessive doses of alfalfa may increase photosensitivity, possibly due to its chlorophyll content. It is unclear if this effect would be clinically relevant in humans.
Sodium Copper Chlorophyllin
Antihypertensive Drugs
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.
Corticosteroids
Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.
Didanosine (Videx)
Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.
Lithium
Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.
Sodium Phosphates
Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.
Sodium-Containing Drugs
Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.
Tolvaptan (Samsca)
Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.
Brand information
Manufacturer and brand details for Chlorophyll 100 mg, from the product label.
NOW
See all NOW products- Name
- NOW Foods
- Street Address
- 395 S. Glen Ellyn Rd.
- City
- Bloomingdale
- State
- IL
- ZipCode
- 60108
- Web Address
- nowfoods.com
Chlorophyll 100 mg by NOW: Common Questions
Does Chlorophyll 100 mg by NOW interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does alfalfa really interfere with warfarin?
What are the most common side effects?
Is this safe during pregnancy?
What is sodium copper chlorophyllin, and why is it in here?
Can I use this if I take birth control?
Does this product have any fillers or 'other ingredients'?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Chlorophyll 100 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Chlorophyll 100 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Alfalfa
Interacts with 583 drugsAlfalfa is a nutrient-rich legume that people use for high cholesterol, menopause symptoms, and general wellness, but solid human evidence for most of these uses is limited. It is best avoid...
Read the full Alfalfa monograph → Herb & supplement monographSodium
Interacts with 205 drugsSodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets get more than enough—often too much—from...
Read the full Sodium monograph →Sources & How We Checked
Chlorophyll 100 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 70 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Alfalfa 32 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
- Kurzer MS, Xu X. Dietary phytoestrogens. Annu Rev Nutr 1997;17:353-81. PubMed
- Farber JM, Carter AO, Varughese PV, et al. Listeriosis traced to the consumption of alfalfa tablets and soft cheese [Letter to the Editor]. N Engl J Med 1990;322:338. PubMed
- Molgaard J, von Schenck H, Olsson AG. Alfalfa seeds lower low density lipoprotein cholesterol and apolipoprotein B concentrations in patients with type II hyperlipoproteinemia. Atherosclerosis 1987;65:173-9. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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