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Dietary supplement

Chlorophyll Ingredients & Drug Interactions

by L.A. Naturals

Chlorophyll label
See full label image
Liquid Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Chlorophyll against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Chlorophyll is a dietary supplement by L.A. Naturals with 1 active ingredient. Its ingredients are commonly taken for body and breath odor reduction, wound healing (topical), detoxification.Based on those ingredients, 337 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Chlorophyll. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Chlorophyll by L.A. Naturals

Ask about any prescription or over-the-counter medication and we check it for interactions with Chlorophyll by L.A. Naturals — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Chlorophyll by L.A. Naturals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.

L.A. Naturals Chlorophyll Liquid contains one active ingredient: chlorophyll, a natural green pigment extracted from plants.

The liquid also contains vegetable glycerin, deionized water, and peppermint oil as inactive ingredients that give it flavor and consistency.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Chlorophyll product and its label doesn't state a use — see Chlorophyll's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for chlorophyll's effectiveness isn't established in the data we hold. We have insufficient reliable evidence to rate it for genital herpes, wound healing, herpes zoster (shingles), nonmelanoma skin cancer, or pancreatitis — the conditions listed in our monograph.

If you're considering it for a specific health goal, talk with your doctor or pharmacist about what the current evidence actually supports.

The evidence, ingredient by ingredient Chlorophyll

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Chlorophyll is generally well tolerated in short-term use, but high-quality safety data are limited. The most common side effect is photosensitization — increased sensitivity to sunlight that can cause a rash or burning.

Rarely, it has triggered pseudoporphyria, a blistering condition in a few people who took chlorophyll drinks. The safety data advise against chlorophyll during pregnancy because there isn't enough reliable information.

Safety during breastfeeding is also unknown, so it's best to avoid it unless your doctor tells you otherwise. Talk with your doctor or pharmacist if you're pregnant, nursing, or planning either.

Side effects, ingredient by ingredient Chlorophyll

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Chlorophyll.
  • The most serious interaction on file is rated Moderate.
  • For scale: 337 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking L.A. Naturals Chlorophyll, check with your doctor or pharmacist if you take methotrexate (Trexall) or any photosensitizing drugs — medications that increase your skin's sensitivity to sunlight.

Chlorophyll may slow methotrexate clearance and add to sun sensitivity from other drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Chlorophyll is one to check before you start, especially if you take methotrexate or drugs that make you sun-sensitive. The evidence for what it actually works for isn't clear in the data we have.

If you're interested in trying it, bring your medication list to your doctor or pharmacist and review it together.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2014.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Chlorophyll, straight from the product label.

Brand L.A. Naturals
Barcode (UPC) 641356129917
Net contents 1 fl. Oz.; 30 mL
Market status On market
Date entered into DSLD Jul 25, 2014
DSLD ID 34878
Product type Non-nutrient/non-botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Chlorophyll by L.A. Naturals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.67 mL
Maximum serving Sizes:
1.33 mL
Servings per container
60
UPC/BARCODE
641356129917
IngredientAmount% DV
Chlorophyll0 NP--

Other ingredients: Vegetable Glycerin, deionized Water, Peppermint Oil

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

SUGGESTED USE: Take 20-40 drops in water or juice, 1-2 times daily, or as needed.

Shake well before using.

Precautions

WARNINGS: STAINS. Keep off clothing.

Keep out of the reach of children.

General Statements

Plant # K-0001604

MADE IN THE USA

FAST ABSORPTION MEDICINAL BOTANICALS ALCOHOL FREE SINGLE HERB

Supports Healthy Blood Cells**

FDA Disclaimer Statement

** These statements have not been evaluated by the FDA. This product is not intended to diagnose, cure, treat, or prevent any disease.

Seals/Symbols

L.a.(TM)

K PARVE

Formulation

ALCOHOL FREE

FDA Statement of Identity

DIETARY SUPPLEMENT

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Chlorophyll by L.A. Naturals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Chlorophyll label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Chlorophyll by L.A. Naturals

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.67 mL Dosage formLiquid Servings per container60 Amounts shown are per serving.

Chlorophyll

Interacts with
337 drugs
0 NP per serving Form: Chlorophyllin Copper compound, Mulberry

Chlorophyll is the green pigment found in plants and algae, and supplements often use a stable form called chlorophyllin. It is most studied for reduc...

Chlorophyll monograph & interactions

Other (inactive) ingredients: Vegetable Glycerin, Deionized Water, Peppermint Oil. These complete the product’s ingredient list but are not active constituents.

Interaction report

Chlorophyll by L.A. Naturals Drug Interactions

Want to check YOUR meds against Chlorophyll?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
337Drugs
337 Moderate

Ingredients driving the most interactions

Chlorophyll 337

Individual Drug Interactions

The ingredients in Chlorophyll interact with 337 drugs. Click any drug to see the details.

1 of the 1 ingredient in Chlorophyll interact with drugs. Each result below shows which ingredient is responsible. Chlorophyll

Each ingredient & the kinds of drugs it affects

For each ingredient in Chlorophyll with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Chlorophyll2 drug types · 337 drugs

Methotrexate (Trexall, Others)

Theoretically, chlorophyll may reduce the clearance of methotrexate.
In one case report, a 54-year-old male developed delayed clearance of intravenous high-dose methotrexate with concomitant use of chlorophyll. When chlorophyll was stopped 2 days prior to methotrexate treatment, methotrexate clearance was unaffected.

Likelihood Possible Evidence B
Photosensitizing Drugs

Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Chlorophyll has been reported to cause photosensitization. In two case reports, pseudoporphyria developed after oral intake of chlorophyll. Theoretically, concomitant use with other photosensitizing drugs may exacerbate this effect.

Likelihood Probable Evidence B
Chlorophyll full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Chlorophyll, from the product label.

L.A. Naturals

See all L.A. Naturals products
Name
Palko Services
Street Address
4991 W. US Hwy 20
City
Michigan City
State
IN
ZipCode
46360
Pharmacist Counseling Corner

Chlorophyll by L.A. Naturals: Common Questions

Does Chlorophyll by L.A. Naturals interact with any medications?
Yes. Based on its ingredients, Chlorophyll has a known interaction with 337 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Chlorophyll contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What does chlorophyll do?
Chlorophyll is a green pigment from plants. We have insufficient reliable evidence to say it's effective for the conditions we've reviewed — herpes, wound healing, shingles, skin cancer, and pancreatitis. If you're considering it for a specific reason, ask your doctor what the evidence actually shows for your goal.
Can I take this while pregnant or breastfeeding?
No — the safety data advise against chlorophyll during pregnancy because there isn't enough reliable information to know it's safe. Safety during breastfeeding is also unknown, so avoid it unless your doctor says otherwise. Talk with your doctor or pharmacist if you're pregnant, nursing, or planning either.
What are the side effects?
The most common side effect is photosensitization — your skin becomes more sensitive to sunlight and can burn or rash more easily. Rarely, it has caused pseudoporphyria, a blistering condition. Significant side effects haven't been widely reported, but a thorough safety evaluation hasn't been done either.
Is it safe to take long-term?
Chlorophyll is generally well tolerated in short-term use, but high-quality safety data for longer-term use are limited. If you're thinking about taking it regularly, talk with your doctor or pharmacist about how long is appropriate for you.
Does it interact with methotrexate?
Yes — in one case report, chlorophyll slowed how a patient's body cleared methotrexate, which could let it build up. Stopping chlorophyll a couple of days before the methotrexate dose prevented the problem. If you take methotrexate, check with your doctor or pharmacist before starting this product.
What happens if I'm on a drug that makes me sun-sensitive?
Chlorophyll itself can cause sun sensitivity, and taking it alongside other sun-sensitizing drugs may add to that effect. Check your medication list with your doctor or pharmacist to see if any of your drugs fall into this category before you start.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Chlorophyll label
Go deeper

The Full Monographs Behind Chlorophyll’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Chlorophyll

Interacts with 337 drugs

Chlorophyll is the green pigment found in plants and algae, and supplements often use a stable form called chlorophyllin. It is most studied for reducing body and fecal odor and as a topical...

Read the full Chlorophyll monograph →
Sources

Sources & How We Checked

Chlorophyll's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Chlorophyll 5 references
  1. Mathews-Roth MM. Carotenoids in erythropoietic protoporphyria and other photosensitivity diseases. Ann N Y Acad Sci, 1993; 691:127-38. PubMed
  2. Belen'kii, G. B. and Krikun, B. L. [Treatment of herpes simplex and herpes zoster by chlorophyll preparations]. Sov.Med. 1971;34(1):151-152.
  3. Brooks SL, Sanders J, Seymour JF, Mellor JD. A case of delayed methotrexate clearance following administration of a complementary medication containing chlorophyll. J Oncol Pharm Pract. 2014 Jun;20(3):225-8. PubMed
  4. Rossi E, Borchard K, Cole JM. Pseudoporphyria following self-medication with chlorophyll. Australas J Dermatol. 2015 Feb;56(1):47-8. PubMed
  5. Zhao CY, Frew JW, Muhaidat J, et al. Chlorophyll-induced pseudoporphyria with ongoing photosensitivity after cessation - a case series of four patients. J Eur Acad Dermatol Venereol 2016;30(7):1239-42. PubMed

See these in context on the Chlorophyll monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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