Cinnamon Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Cinnamon against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Cinnamon is a dietary supplement by L.A. Naturals with 3 active ingredients. Its ingredients are commonly taken for blood sugar support, digestive upset, antioxidant support.Based on those ingredients, 442 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Certified Organic Cinnamon bark ETOH extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Cinnamon by L.A. Naturals
Ask about any prescription or over-the-counter medication and we check it for interactions with Cinnamon by L.A. Naturals — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Cinnamon by L.A. Naturals
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains 3 active ingredients, both forms of cinnamon extract. You get a Certified Organic Cinnamon bark extract made with alcohol (ETOH extract) and a Cinnamon bark Supercritical CO2 extract — two different ways to concentrate cinnamon's compounds.
The third active ingredient, Standardized Cinnamaldehydes, is the compound that gives cinnamon its characteristic smell and flavor. The capsules also contain two inactive ingredients: non-GMO soy lecithin and vegetable cellulose.
Does it work?
Not established
The evidence we hold doesn't establish effectiveness for the uses listed—amenorrhea, angina, common cold, diabetes, diarrhea, or dyslipidemia (high cholesterol and triglycerides). For all of these, the rating is insufficient reliable evidence.
That doesn't mean cinnamon doesn't work; it means the clinical trials available to us haven't proven it does.
How safe is it?
Well-documented data
Cinnamon is generally well tolerated in food amounts. Supplement doses, especially high ones taken long-term, are a different story because of coumarin content.
The main concern is liver harm over time with sustained high-dose use. A small number of trial participants reported side effects: one person developed a rash after taking 1 gram daily for 90 days, and one person with a documented cinnamic alcohol allergy developed contact dermatitis (skin inflammation) that cleared five days after stopping.
One trial also reported a low blood sugar seizure (hypoglycemic seizure) in a participant, though the timing makes it unclear whether cinnamon caused it. For pregnancy and breastfeeding, food amounts are likely safe, but the data advises against medicinal or high-dose supplement amounts during pregnancy and lactation due to limited safety data.
Meds to double-check
Moderate interaction found
Before taking this, check your list of medications against these two types: diabetes medications (blood sugar drugs) and any drug that can stress your liver. Both carry Moderate severity interactions with the cinnamon in this product.
Use the search tool on this page to look up your exact drugs.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
If you take diabetes medication or drugs that can affect your liver, check with your pharmacist before starting this. For most people using supplement doses, cinnamon is generally tolerated, but don't take high doses long-term without knowing the coumarin risk.
Talk to your pharmacist about whether this fits your medications and health.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2014.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Cinnamon, straight from the product label.
| Brand | L.A. Naturals |
|---|---|
| Barcode (UPC) | 641356121003 |
| Net contents | 60 Liquid Veggie Cap(s) |
| Market status | On market |
| Date entered into DSLD | Jun 25, 2014 |
| DSLD ID | 34856 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Cinnamon by L.A. Naturals, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Certified Organic Cinnamon bark ETOH extract | 250 mg | -- |
| Cinnamon bark Supercritical CO2 extract | 75 mg | -- |
| Standardized Cinnamaldehydes | 40 mg | -- |
Other ingredients: non-GMO Soy Lecithin, Vegetable Cellulose
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
100% Vegetarian
No Gluten, No Dairy (Milk or Lactose), No Nuts, No Egg, No Fish or Shellfish, Suitable for Vegetarians, No Artificial Preservatives, Sweeteners or Colors
No Gluten, No Dairy (Milk or Lactose), No Nuts, No Egg, No Fish or Shellfish, Suitable for Vegetarians, No Artificial Preservatives, Sweeteners or Colors
General Statements
Supports Healthy Blood Sugar
MADE IN THE USA
1,900 mg Herb Weight Equivalence
SINGLE LIQUID EXTRACT MEDICINAL BOTANICALS POWERFUL EXTRACTS
FDA Statement of Identity
DIETARY SUPPLEMENT
Seals/Symbols
CAP-PRO
L.a.(TM)
Suggested/Recommended/Usage/Directions
SUGGESTED USE: Take 1 cap 2 times per day or as directed by your healthcare professional.
Precautions
WARNINGS: Do not take during pregnancy.
Keep out of the reach of children.
FDA Disclaimer Statement
These statements have not been evaluated by the FDA. This product is not intended to diagnose, cure, treat, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Cinnamon by L.A. Naturals label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Cinnamon by L.A. Naturals
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Veggie Cap(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Certified Organic Cinnamon bark ETOH extract
Interacts with442 drugs
Cassia cinnamon is the common, inexpensive cinnamon used in cooking, and it is also taken as a supplement, most often for blood sugar support. The evi...
Certified Organic Cinnamon bark ETOH extract monograph & interactionsCinnamon bark Supercritical CO2 extract
Interacts with442 drugs
Cassia cinnamon is the common, inexpensive cinnamon used in cooking, and it is also taken as a supplement, most often for blood sugar support. The evi...
Cinnamon bark Supercritical CO2 extract monograph & interactionsStandardized Cinnamaldehydes
Other (inactive) ingredients: Non-GMO Soy Lecithin, Vegetable Cellulose. These complete the product’s ingredient list but are not active constituents.
Cinnamon by L.A. Naturals Drug Interactions
HelloPharmacist Interaction Report
Cinnamon by L.A.
Naturals contains two cinnamon extracts that both link to the same monograph (Cassia Cinnamon), and both carry documented interactions with two drug categories. Altogether, these interactions span 425 individual medications.
Read the full breakdown — every affected drug type, severity by severity
The most serious concern is with drugs that stress the liver (hepatotoxic drugs). Large doses of cassia cinnamon taken over a long time might add to that liver stress.
Cassia cinnamon contains coumarin, which can damage the liver in animal studies. In humans, very high doses of coumarin (50–7000 mg per day) have caused liver damage that improved when the coumarin stopped, but the cinnamon doses used in clinical trials (360 mg to 12 grams daily for 3 months) did not significantly raise liver enzyme levels.
The second interaction is with diabetes medications (antidiabetes drugs). Cassia cinnamon may lower blood sugar levels, so it could add to the effect of your diabetes medication and theoretically require dose adjustments.
We could not check the third ingredient, Standardized Cinnamaldehydes, because we hold no data for it. Use the medication checker on this page to search your exact prescriptions before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Cinnamon?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Cinnamon interact with 442 drugs. Click any drug to see the details.
1 of the 3 ingredients in Cinnamon interact with drugs. Each result below shows which ingredient is responsible. Certified Organic Cinnamon bark ETOH extract
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Supercritical Co2 ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Supercritical Co2 Extract + 6-mercaptopurine interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Supercritical Co2 ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Supercritical Co2 Extract + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Supercritical Co2 ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Supercritical Co2 Extract + Abacavir, Lamivudine interactionAbiraterone
How Abiraterone interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Supercritical Co2 ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Supercritical Co2 Extract + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Supercritical Co2 ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Supercritical Co2 Extract + Abiraterone Acetate interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Supercritical Co2 ExtractAntidiabetes Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, cassia cinnamon may have additive effects with antidiabetes drugs.
Read the full Cinnamon Bark Supercritical Co2 Extract + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Supercritical Co2 ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Supercritical Co2 Extract + Acebutolol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Supercritical Co2 ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Supercritical Co2 Extract + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Supercritical Co2 ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Supercritical Co2 Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Supercritical Co2 ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Supercritical Co2 Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Supercritical Co2 ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Supercritical Co2 Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Supercritical Co2 ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Supercritical Co2 Extract + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Supercritical Co2 ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Supercritical Co2 Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Supercritical Co2 ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Supercritical Co2 Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Supercritical Co2 ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Supercritical Co2 Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Supercritical Co2 ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Supercritical Co2 Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Supercritical Co2 ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Supercritical Co2 Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Supercritical Co2 ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Supercritical Co2 Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Supercritical Co2 ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Supercritical Co2 Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Supercritical Co2 ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Supercritical Co2 Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Supercritical Co2 ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Supercritical Co2 Extract + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Supercritical Co2 ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Supercritical Co2 Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Supercritical Co2 ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Supercritical Co2 Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Supercritical Co2 ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Supercritical Co2 Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Supercritical Co2 ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Supercritical Co2 Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Supercritical Co2 ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Supercritical Co2 Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Supercritical Co2 ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Supercritical Co2 Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Supercritical Co2 ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Supercritical Co2 Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Supercritical Co2 ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Supercritical Co2 Extract + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark Supercritical Co2 ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Supercritical Co2 Extract + Acetaminophen, Chlorpheniramine, Phenylephrine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Cinnamon with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Certified Organic Cinnamon bark ETOH extract
Antidiabetes Drugs
Theoretically, cassia cinnamon may have additive effects with antidiabetes drugs.
Cassia cinnamon may lower blood glucose levels, and have additive effects in patients treated with antidiabetic agents. Dose adjustments to diabetes medications might be necessary.
Hepatotoxic Drugs
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
There is some concern that ingesting large amounts of cassia cinnamon for an extended duration might cause hepatotoxicity in some people. Cassia cinnamon contains coumarin, which can cause hepatotoxicity in animal models. In humans, very high doses of coumarin from 50-7000 mg/day can result in hepatotoxicity that resolves when coumarin use is discontinued. Lower amounts might also cause liver problems in sensitive people, such as those with liver disease or those taking potentially hepatotoxic agents.
Brand information
Manufacturer and brand details for Cinnamon, from the product label.
L.A. Naturals
See all L.A. Naturals products- Name
- Palko Services
- Street Address
- 4991 W. US Hwy 20
- City
- Michigan City
- State
- IN
- ZipCode
- 46360
Cinnamon by L.A. Naturals: Common Questions
Does Cinnamon by L.A. Naturals interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is this safe to take if I'm pregnant or breastfeeding?
Will cinnamon help with my blood sugar or cholesterol?
What's the coumarin concern I keep hearing about?
Can cinnamon cause a rash or allergic reaction?
What does the Supercritical CO2 extract mean?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Cinnamon is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Cinnamon’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Cinnamon's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 20 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Cassia Cinnamon 20 references
- Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
- Khan A, Safdar M, Ali Khan M, et al. Cinnamon improves glucose and lipids of people with type 2 diabetes. Diabetes Care 2003;26:3215-8. PubMed
- De Benito V, Alzaga R. Occupational allergic contact dermatitis from cassia (Chinese cinnamon) as a flavouring agent in coffee. Contact Dermatitis 1999;40:165. PubMed
- Drake TE, Maibach HI. Allergic contact dermatitis and stomatitis caused by a cinnamic aldehyde-flavored toothpaste. Arch Dermatol 1976;112:202-3.
- Press release. Cinnamon capsules to reduce blood sugar are medicinal products! Efficacy has not been scientifically proven - some products contain high levels of coumarin. Federal Institute of Risk Assessment (BfM), Germany, November 11, 2006. Available a
- Felter SP, Vassallo JD, Carlton BD, Daston GP. A safety assessment of coumarin taking into account species-specificity of toxicokinetics. Food Chem Toxicol 2006;44:462-75. PubMed
- Crawford P. Effectiveness of cinnamon for lowering hemoglobin A1C in patients with type 2 diabetes: a randomized, controlled trial. J Am Board Fam Med 2009;22:507-12. PubMed
- Akilen, R., Tsiami, A., Devendra, D., and Robinson, N. Glycated haemoglobin and blood pressure-lowering effect of cinnamon in multi-ethnic Type 2 diabetic patients in the UK: a randomized, placebo-controlled, double-blind clinical trial. Diabet.Med. 2010; PubMed
- Lu T, Sheng H Wu J Cheng Y Zhu J Chen Y. Cinnamon extract improves fasting blood glucose and glycosylated hemoglobin level in Chinese patients with type 2 diabetes. Nutr Res. 2012;32(6):408-412. PubMed
- Choi, J., Lee, K. T., Ka, H., Jung, W. T., Jung, H. J., and Park, H. J. Constituents of the essential oil of the Cinnamomum cassia stem bark and the biological properties. Arch Pharm Res 2001;24(5):418-423.
- Altschuler JA, Casella SJ, MacKenzie TA, Curtis KM. The effect of cinnamon on A1C among adolescents with type 1 diabetes. Diabetes Care 2007;30(4):813-6. PubMed
- Stoecker BR, Zhan Z, Luo R, et al. Cinnamon extract lowers blood glucose in hyperglycemic subjects. FASEB J. 2010;22:722.1 (Abstract only). DOI
- Admani S, Hill H, Jacob SE. Cinnamon Sugar Scrub Dermatitis: "Natural" Is Not Always Best. Pediatr Dermatol. 2017;34(1):e42-e43. PubMed
- Isaac-Renton M, Li MK, Parsons LM. Cinnamon spice and everything not nice: many features of intraoral allergy to cinnamic aldehyde. Dermatitis. 2015;26(3):116-21. PubMed
- Vandersall A, Katta R. Eyelid dermatitis as a manifestation of systemic contact dermatitis to cinnamon. Dermatitis. 2015 Jul-Aug;26(4):189. PubMed
- Wickenberg J, Lindstedt S, Nilsson J, Hlebowicz J. Cassia cinnamon does not change the insulin sensitivity or the liver enzymes in subjects with impaired glucose tolerance. Nutr J 2014 Sep 24;13:96. PubMed
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