Interactions on record — worth a quick check against your medications. Based on 1 of 5 ingredients. Check your meds →
Dietary supplement

CLA 1000 mg Ingredients & Drug Interactions

by BioGanix

CLA 1000 mg label
See full label image
Softgel Capsule Category: Fat/fatty Acid
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking CLA 1000 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

CLA 1000 mg is a dietary supplement by BioGanix with 5 active ingredients. Its ingredients are commonly taken for heart health, healthy cooking fat, skin moisturizing.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Oleic Acid. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against CLA 1000 mg by BioGanix

Ask about any prescription or over-the-counter medication and we check it for interactions with CLA 1000 mg by BioGanix — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of CLA 1000 mg by BioGanix

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 5 of its 5 active ingredients.
  • “Conjugated Linoleic Acid” is listed as a grouped ingredient — the label gives one combined amount (1,000 mg) without saying how much of each component you get.

CLA 1000 mg contains five active ingredients, all fatty acids: conjugated linoleic acid (the primary ingredient that gives this product its name), along with stearic acid, linoleic acid, oleic acid, and palmitic acid. These are delivered in a softgel capsule with gelatin, glycerin, and purified water as inactive ingredients.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Oleic Acid's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: support healthy weight loss and lean muscle mass.
  • We looked for evidence on: Obesity, body composition, metabolic health, weight management.
  • The closest evidence on file: Oleic Acid is rated "Insufficient Reliable Evidence To Rate" for Obesity (Natural Medicines).

Oleic acid in this product has been rated possibly effective for high cholesterol (hypercholesterolemia) and possibly effective for heart disease risk (coronary heart disease). We hold no effectiveness data in our system for the other fatty acids in this formula.

The evidence, ingredient by ingredient Oleic Acid

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Oleic acid is generally recognized as safe when you consume it in normal food amounts — olive oil is a common dietary source. However, concentrated supplement doses of oleic acid haven't been well studied in pregnancy or breastfeeding.

If you're pregnant, nursing, or planning to become pregnant, there isn't enough safety data to know whether a supplement-level dose is appropriate, so talk with your doctor or pharmacist for personalized advice. No adverse effects were reported in the data we hold for this product.

Side effects, ingredient by ingredient Oleic Acid

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Oleic Acid.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your antidiabetes medications (drugs that lower blood sugar) before taking this product. Oleic acid may increase their effects, which means your blood sugar could drop lower than expected.

Your doctor or pharmacist can tell you whether that's a concern for your specific situation and dosage.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and some safety-information gaps remain.

CLA 1000 mg may interest you if you're looking to support cholesterol or heart health, based on the possibly effective rating for oleic acid. If you take diabetes medication, check your exact drugs with the tool on this page before starting — the oleic acid could strengthen blood sugar-lowering effects.

Talk with your doctor or pharmacist before adding this to your routine, especially if you're pregnant, nursing, or on any prescription medication.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about CLA 1000 mg, straight from the product label.

Brand BioGanix
Barcode (UPC) X001KR0JHR
Net contents 200 Softgel(s)
Market status On market
Date entered into DSLD Jul 23, 2020
DSLD ID 230973
Product type Fat/fatty Acid
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for CLA 1000 mg by BioGanix, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
200
UPC/BARCODE
X001KR0JHR
IngredientAmount% DV
Stearic Acid30 mg--
Conjugated Linoleic Acid780 mg--
Linoleic Acid10 mg--
Oleic Acid150 mg--
Palmitic Acid30 mg--
Conjugated Linoleic Acid1000 mg--

Other ingredients: Gelatin, Glycerin, purified Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

BioGanix CLA (Conjugated Linoleic Acid) is a naturally occurring essential fatty acid that is thought to support healthy weight loss by boosting metabolism, reducing body fat, and improving lean muscle mass.

CLA 1000 mg from Safflower

100% Natural with no artificial ingredients

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take one (1) softgel capsule two (2) to three (3) times daily with food. For best results, take it every day or as advised by your healthcare provider. For maximum results combine with proper diet, exercise, and BioGanix Ultra Omega-3 FIsh oil.

Precautions

Caution: Do not exceed recommended dose.

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Keep out of the reach of children.

Do not use if safety seal is damaged or missing.

Storage

Store at room temperature.

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Like us on FB for deals & giveaways: www.facebook.com/bioganixhealth Free $10 gift card & coupon code here: www.bioganix.com/go/giftcard1

Conjugated Linoleic...id (CLA) 1000 mg 200 ct NEW

Formulation

Stimulant free

Natural weight management May enhance fat reduction Supports weight loss Promotes lean muscle mass development May help boost metabolism

Non-GMO

100% Natural with no artificial ingredients No preservatives, no GMO's, no stimulants

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

GMP Good Manufacturing Practice Consistent Quality Made in the USA FDA Registered Facility

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

CLA 1000 mg by BioGanix label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

CLA 1000 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in CLA 1000 mg by BioGanix

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container200 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Conjugated Linoleic Acid

1000 mg per serving Form: Safflower Seed Oil
  • › Stearic Acid
  • › Conjugated Linoleic Acid
  • › Linoleic Acid
  • › Oleic Acid
  • › Palmitic Acid

Other (inactive) ingredients: Gelatin, Glycerin, Purified Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

CLA 1000 mg by BioGanix Drug Interactions

Want to check YOUR meds against CLA 1000 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Oleic Acid 86

Individual Drug Interactions

The ingredients in CLA 1000 mg interact with 86 drugs. Click any drug to see the details.

1 of the 5 ingredients in CLA 1000 mg interact with drugs. Each result below shows which ingredient is responsible. Oleic Acid

Each ingredient & the kinds of drugs it affects

For each ingredient in CLA 1000 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Oleic Acid1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, oleic acid might increase the effects of antidiabetes drugs. Preliminary clinical research in patients with type 2 diabetes taking oral hypoglycemic drugs shows that eating a diet rich in oleic acid from olive oil decreases fasting blood glucose levels when compared to eating a diet rich in linoleic acid from sunflower oil. It is unknown if taking oleic acid supplements would have this effect or if this change is clinically significant. Until more is known, use caution. Dose adjustment may be necessary. Some antidiabetes drugs include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, metformin (Glucophage), pioglitazone (Actos), rosiglitazone (Avandia), and others.

Likelihood Possible Evidence B
Oleic Acid full monograph & interactions
The maker

Brand information

Manufacturer and brand details for CLA 1000 mg, from the product label.

BioGanix

See all BioGanix products
Name
BioGanix (BGX E-Health LLC)
Street Address
4700 Millenia Boulevard, Suite 175
City
Orlando
State
FL
ZipCode
32839
Phone Number
1-888-506-1558
Web Address
www.BioGanix.com
Pharmacist Counseling Corner

CLA 1000 mg by BioGanix: Common Questions

Does CLA 1000 mg by BioGanix interact with any medications?
Yes. Based on its ingredients, CLA 1000 mg has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
CLA 1000 mg contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is CLA and what does it do in my body?
CLA stands for conjugated linoleic acid — it's a type of fat found naturally in meat and dairy. This product contains CLA along with other fatty acids like oleic acid. The oleic acid has been rated possibly effective for supporting cholesterol levels and heart health, but we don't have effectiveness data for the other fatty acids in the formula.
Will this affect my diabetes medication?
The oleic acid in this product may increase the effects of antidiabetes drugs based on preliminary research. That means your blood sugar could drop lower than expected. Talk with your doctor or pharmacist before starting to make sure the product and your current dose work safely together.
Is this safe to take if I'm pregnant or breastfeeding?
Food amounts of oleic acid are considered safe, but we don't have enough safety data for concentrated supplement doses in pregnancy or breastfeeding. Your doctor or pharmacist can give you personalized advice based on your situation.
What's in the capsule besides the fatty acids?
The softgel is made from gelatin, glycerin, and purified water. These are inactive ingredients that help deliver the active fatty acids.
Are there any side effects I should know about?
No adverse effects are reported in the data we hold for this product. That said, any new supplement can affect how you feel — if you notice anything unusual after starting it, let your pharmacist or doctor know.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if CLA 1000 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

CLA 1000 mg label
Go deeper

The Full Monographs Behind CLA 1000 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Oleic Acid

Interacts with 86 drugs

Oleic acid is a heart-healthy monounsaturated fat found mainly in olive oil, canola oil, avocados, and nuts. As part of a Mediterranean-style diet, it is widely viewed as a healthier replace...

Read the full Oleic Acid monograph →
Sources

Sources & How We Checked

CLA 1000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 19 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Oleic Acid 19 references
  1. Madigan C, Ryan M, Owens D, et al. Dietary unsaturated fatty acids in type 2 diabetes: higher levels of postprandial lipoprotein on a linoleic acid-rich sunflower oil diet compared with an oleic acid-rich olive oil diet. Diabetes Care 2000;23:1472-7. PubMed
  2. Gillingham, L. G., Gustafson, J. A., Han, S. Y., Jassal, D. S., and Jones, P. J. High-oleic rapeseed (canola) and flaxseed oils modulate serum lipids and inflammatory biomarkers in hypercholesterolaemic subjects. Br J Nutr 2011;105(3):417-427. PubMed
  3. Jones PJ, Senanayake VK, Pu S, Jenkins DJ, Connelly PW, Lamarche B, Couture P, Charest A, Baril-Gravel L, West SG, Liu X, Fleming JA, McCrea CE, Kris-Etherton PM. DHA-enriched high-oleic acid canola oil improves lipid profile and lowers predicted cardiova
  4. Cater, N. B., Heller, H. J., and Denke, M. A. Comparison of the effects of medium-chain triacylglycerols, palm oil, and high oleic acid sunflower oil on plasma triacylglycerol fatty acids and lipid and lipoprotein concentrations in humans. Am.J Clin.Nutr PubMed
  5. Mozaffarian D, Clarke R. Quantitative effects on cardiovascular risk factors and coronary heart disease risk of replacing partially hydrogenated vegetable oils with other fats and oils. Eur J Clin Nutr. 2009;63(Suppl 2):S22-33. PubMed
  6. Cao Y, Hou L, Wang W. Dietary total fat and fatty acids intake, serum fatty acids and risk of breast cancer: A meta-analysis of prospective cohort studies. Int J Cancer. 2016;138(8):1894-904. doi: 10.1002/ijc.29938. PubMed
  7. FDA completes review of qualified health claim petition for oleic acid and the risk of coronary heart disease. November 2018. Available at: www.fda.gov/Food/NewsEvents/ConstituentUpdates/ucm624758.htm. Accessed January 25, 2019.
  8. Liu X, Kris-Etherton PM, West SG, et al. Effects of canola and high-oleic-acid canola oils on abdominal fat mass in individuals with central obesity. Obesity. 2016;24(11):2261-2268. PubMed
  9. Bowen KJ, Kris-Etherton PM, West SG, et al. Diets enriched with conventional or high-oleic acid canola oils lower atherogenic lipids and lipoproteins compared to a diet with a western fatty acid profile in adults with central adiposity. J Nutr. 2019;149(3 PubMed
  10. Steffen BT, Duprez D, Szklo M, Guan W, Tsai MY. Circulating oleic acid levels are related to greater risks of cardiovascular events and all-cause mortality: The Multi-Ethnic Study of Atherosclerosis. J Clin Lipidol. 2018;12(6):1404-1412. PubMed
  11. Banim PJ, Luben R, Khaw KT, Hart AR. Dietary oleic acid is inversely associated with pancreatic cancer - Data from food diaries in a cohort study. Pancreatology. 2018;18(6):655-660. PubMed
  12. Morin SJ, Gaziano JM, Djoussé L. Relation between plasma phospholipid oleic acid and risk of heart failure. Eur J Nutr. 2018;57(8):2937-2942. PubMed
  13. Samieri C, Féart C, Proust-Lima C, et al. Olive oil consumption, plasma oleic acid, and stroke incidence: the Three-City Study. Neurology. 2011;77(5):418-25. PubMed
  14. Compher CW, Kinosian BP, Rubesin SE, Ratcliffe SJ, Metz DC. Energy absorption is reduced with oleic acid supplements in human short bowel syndrome. JPEN J Parenter Enteral Nutr. 2009;33(1):102-8. PubMed
  15. Ben Fradj MK, Ouanes Y, Hadj-Taieb S, et al. Decreased oleic acid and marine n?-?3 polyunsaturated fatty acids in Tunisian patients with urothelial bladder cancer. Nutr Cancer. 2018;70(7):1043-1050.
  16. de Silva PS, Luben R, Shrestha SS, Khaw KT, Hart AR. Dietary arachidonic and oleic acid intake in ulcerative colitis etiology: a prospective cohort study using 7-day food diaries. Eur J Gastroenterol Hepatol. 2014;26(1):11-8. PubMed
  17. Higashi K, Shige H, Ito T, et al. Effect of a low-fat diet enriched with oleic acid on postprandial lipemia in patients with type 2 diabetes mellitus. Lipids. 2001;36(1):1-6. PubMed
  18. Lin HC, van Citters GW, Heimer F, Bonorris G. Slowing of gastrointestinal transit by oleic acid: a preliminary report of a novel, nutrient-based treatment in humans. Dig Dis Sci. 2001;46(2):223-9. PubMed
  19. Li D, Tong Y, Li Y. Associations between dietary oleic acid and linoleic acid and depressive symptoms in perimenopausal women: The Study of Women's Health Across the Nation. Nutrition. 2020 Mar;71:110602. PubMed

See these in context on the Oleic Acid monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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