Clear Whey Protein Watermelon Fresca Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Clear Whey Protein Watermelon Fresca against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Clear Whey Protein Watermelon Fresca is a dietary supplement by Oath Nutrition with 3 active ingredients. Its ingredients are commonly taken for replacing fluids and electrolytes, preventing dehydration during exercise or illness, treating low blood sodium (under medical care).Based on those ingredients, 258 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Sodium, Whey Protein Isolate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Clear Whey Protein Watermelon Fresca by Oath Nutrition
Ask about any prescription or over-the-counter medication and we check it for interactions with Clear Whey Protein Watermelon Fresca by Oath Nutrition — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Clear Whey Protein Watermelon Fresca by Oath Nutrition
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Partial disclosure
This powder contains 2 active ingredients: sodium and whey protein isolate. Whey protein isolate is a concentrated form of protein derived from milk; it's used in athletic performance and fitness contexts.
Sodium is an electrolyte your body needs in small amounts for nerve and muscle function. The product also contains inactive ingredients (coconut milk powder, natural flavors, malic acid, citric acid, sucralose, and vegetable juice) that provide taste and texture.
Does it work?
Moderate evidence
The evidence on whey protein isolate for athletic performance is limited—it's possibly effective based on available data we hold, but more research is needed. For other claimed uses like bone health or cognitive decline, the evidence doesn't support it, or we don't have enough data to say either way.
Sodium's effectiveness is rated for specific medical conditions like cystic fibrosis (likely effective) and amphotericin B kidney toxicity (possibly effective), but this product is not formulated as a treatment for those conditions. As a supplement, the evidence on its effectiveness for general fitness or health maintenance isn't established in our data.
How safe is it?
Well-documented data
Whey protein isolate is generally well tolerated by most healthy adults, though some people report bloating, cramps, diarrhea, nausea, headache, acne, or reflux—most of these are dose-related and resolve with less intake. Sodium is fine at normal dietary amounts, but too much is linked to high blood pressure, kidney disease, and heart strain.
The product's safety in pregnancy and lactation isn't fully established—one rating suggests sodium may be possibly unsafe during pregnancy, while whey has incomplete data. If you're pregnant or breastfeeding, talk with your doctor before starting this product.
Meds to double-check
Major interaction found
Do not take this product without checking with your pharmacist if you take levodopa (Parkinson's disease), blood pressure medications (antihypertensives), lithium (bipolar disorder), quinolone or tetracycline antibiotics, bisphosphonates (bone health), or any sodium-containing prescription drugs. These interactions are serious enough that timing or skipping the product may be necessary.
The bottom line
Scorecard at a glancePartially disclosed formula with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.
If you take levodopa, blood pressure medications, lithium, antibiotics, or bone medications, check your specific drugs with the tool on this page before using this product. If you're generally healthy and don't take those medications, it's likely okay, but pregnant or breastfeeding individuals should talk with their doctor first.
A pharmacist can help you time this product away from other medications if needed.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 24, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Clear Whey Protein Watermelon Fresca, straight from the product label.
| Brand | Oath Nutrition |
|---|---|
| Barcode (UPC) | 847280087679 |
| Net contents | 18.62 Ounce(s); 1.16 Pound(s); 528 Gram(s) |
| Market status | On market |
| Date entered into DSLD | Apr 24, 2025 |
| DSLD ID | 332973 |
| Product type | Amino Acid/protein |
| Supplement form | Powder |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Clear Whey Protein Watermelon Fresca by Oath Nutrition, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 100 Calorie(s) | -- |
| Total Carbohydrates | 2 Gram(s) | 1% |
| Sodium | 10 mg | 1% |
| Total Sugars | 1 Gram(s) | -- |
| Cholesterol | 5 mg | 1% |
| Total Fat | 0.5 Gram(s) | 1% |
| Saturated Fat | 0.5 Gram(s) | 3% |
| Protein | 20 Gram(s) | 40% |
| Whey Protein Isolate | 0 NP | -- |
Other ingredients: Coconut Milk, Powder, Natural Flavors, Malic Acid, Citric Acid, Sucralose, Vegetable Juice
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Watermelon Fresca Flavored with natural & artificial flavors 20 grams of complete protein per serving
This whey protein thinks it's a fancy watermelon mixer. Light, refreshing flavor infused with 20 g of high-quality protein - you don't know if you're at a beach or at the gym. Either way, your muscles win. Welcome to the protein party.
Contains < 1% fruit juice.
What in the world is "clear whey"? The easy answer: Protein that tastes like fruit juice. You're welcome. The nerdy answer: Whey protein isolate that's been hydrolyzed or clarified - changing the texture from thick and creamy to lightweight and juicy. Mmmm...magic. Everyday, all-day protein.
Formulation
Fast absorption & recovery Light & refreshing flavor
Made in the USA using globally-sourced ingredients and components.
Gymming Desking Streaming Hula hooping Desserting
FDA Statement of Identity
Dietary Supplement
Brand IP Statement(s)
Oath Nutrition is a trademark of and is distributed by: Trove Nutrition, LLC
Precautions
Notice: Use this product as a supplement only. Do not use for weight reduction.
Contains: milk and coconut.
Not intended for persons under the age of 18. Keep out of reach of children.
Do not use if pregnant or nursing. Consult a healthcare professional prior to consumption if you have any pre-existing medical conditions or are taking any prescription medication.
Excessive use of this product will not improve results. Use only as directed. Do not use if safety seal is damaged or missing.
Suggested/Recommended/Usage/Directions
Directions: Mix 1 scoop with 14-16 fl. ounces of cold water. Enjoy throughout the day to meet individual protein requirements.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Storage
Store in a cool, dry place.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Clear Whey Protein Watermelon Fresca by Oath Nutrition label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Clear Whey Protein Watermelon Fresca by Oath Nutrition
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size26.4 Gram(s) Dosage formPowder Servings per container20 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Sodium
Interacts with205 drugs
Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...
Sodium monograph & interactionsProtein
Whey Protein Isolate
Interacts with53 drugs
Whey protein is a high-quality, complete protein made from cow's milk that can help people meet protein needs and support muscle growth when combined...
Whey Protein Isolate monograph & interactionsOther (inactive) ingredients: Coconut Milk, Powder, Natural Flavors, Malic Acid, Citric Acid, Sucralose, Vegetable Juice. These complete the product’s ingredient list but are not active constituents.
Clear Whey Protein Watermelon Fresca by Oath Nutrition Drug Interactions
HelloPharmacist Interaction Report
Clear Whey Protein Watermelon Fresca by Oath Nutrition contains sodium and whey protein isolate, both of which interact with medications.
Whey protein isolate carries the most serious concern: it may significantly reduce how your body absorbs levodopa, a Parkinson's disease medication. Taking them together can worsen tremor, muscle stiffness, and symptom fluctuations.
Read the full breakdown — every affected drug type, severity by severity
Sodium in this product can interfere with blood pressure medications (antihypertensives), lithium for bipolar disorder, and several other drugs by either reducing their effectiveness or raising sodium levels to unsafe amounts. These interactions are all Moderate severity.
Whey protein also contains minerals like calcium that can bind to and reduce absorption of quinolone and tetracycline antibiotics, as well as bisphosphonates for bone health—again, Moderate severity.
Altogether, these interactions span 256 individual medications. Before you start this product, especially if you take levodopa, blood pressure medications, lithium, antibiotics, bone medications, or sodium-containing prescriptions, run your exact medications through the checker below.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Clear Whey Protein Watermelon Fresca?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Clear Whey Protein Watermelon Fresca interact with 258 drugs. Click any drug to see the details.
2 of the 3 ingredients in Clear Whey Protein Watermelon Fresca interact with drugs. Each result below shows which ingredient is responsible. Sodium Whey Protein Isolate
Benserazide, LevodopaMadopar, Prolopa
How Benserazide, Levodopa interacts with Clear Whey Protein Watermelon Fresca — through 1 ingredient. Tap an ingredient for the detail:
Whey Protein IsolateLevodopa Major
Interaction Summary
Theoretically, whey protein might decrease levodopa absorption.
Read the full Whey Protein Isolate + Benserazide, Levodopa interactionCarbidopa, LevodopaDhivy, Rytary, Sinemet, Sinemet CR
How Carbidopa, Levodopa interacts with Clear Whey Protein Watermelon Fresca — through 1 ingredient. Tap an ingredient for the detail:
Whey Protein IsolateLevodopa Major
Interaction Summary
Theoretically, whey protein might decrease levodopa absorption.
Read the full Whey Protein Isolate + Carbidopa, Levodopa interactionCarbidopa, Levodopa, EntacaponeStalevo
How Carbidopa, Levodopa, Entacapone interacts with Clear Whey Protein Watermelon Fresca — through 1 ingredient. Tap an ingredient for the detail:
Whey Protein IsolateLevodopa Major
Interaction Summary
Theoretically, whey protein might decrease levodopa absorption.
Read the full Whey Protein Isolate + Carbidopa, Levodopa, Entacapone interactionLevodopaInbrija, Larodopa
How Levodopa interacts with Clear Whey Protein Watermelon Fresca — through 1 ingredient. Tap an ingredient for the detail:
Whey Protein IsolateLevodopa Major
Interaction Summary
Theoretically, whey protein might decrease levodopa absorption.
Read the full Whey Protein Isolate + Levodopa interactionLevodopa, CarbidopaDuodopa
How Levodopa, Carbidopa interacts with Clear Whey Protein Watermelon Fresca — through 1 ingredient. Tap an ingredient for the detail:
Whey Protein IsolateLevodopa Major
Interaction Summary
Theoretically, whey protein might decrease levodopa absorption.
Read the full Whey Protein Isolate + Levodopa, Carbidopa interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Clear Whey Protein Watermelon Fresca — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Acebutolol interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Clear Whey Protein Watermelon Fresca — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Acetazolamide interactionAlendronateBinosto, Fosamax
How Alendronate interacts with Clear Whey Protein Watermelon Fresca — through 1 ingredient. Tap an ingredient for the detail:
Whey Protein IsolateBisphosphonates Moderate
Interaction Summary
Theoretically, whey protein might reduce the absorption of bisphosphonates.
Read the full Whey Protein Isolate + Alendronate interactionAlendronate Sodium
How Alendronate Sodium interacts with Clear Whey Protein Watermelon Fresca — through 1 ingredient. Tap an ingredient for the detail:
Whey Protein IsolateBisphosphonates Moderate
Interaction Summary
Theoretically, whey protein might reduce the absorption of bisphosphonates.
Read the full Whey Protein Isolate + Alendronate Sodium interactionAlendronate Sodium, CholecalciferolFosamax Plus D
How Alendronate Sodium, Cholecalciferol interacts with Clear Whey Protein Watermelon Fresca — through 1 ingredient. Tap an ingredient for the detail:
Whey Protein IsolateBisphosphonates Moderate
Interaction Summary
Theoretically, whey protein might reduce the absorption of bisphosphonates.
Read the full Whey Protein Isolate + Alendronate Sodium, Cholecalciferol interactionAliskirenTekturna
How Aliskiren interacts with Clear Whey Protein Watermelon Fresca — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Aliskiren interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with Clear Whey Protein Watermelon Fresca — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Ambrisentan interactionAmilorideAmilamont, Midamor
How Amiloride interacts with Clear Whey Protein Watermelon Fresca — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Amiloride interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Clear Whey Protein Watermelon Fresca — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Amiloride, Hydrochlorothiazide interactionAmlodipineNorliqva
How Amlodipine interacts with Clear Whey Protein Watermelon Fresca — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with Clear Whey Protein Watermelon Fresca — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with Clear Whey Protein Watermelon Fresca — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with Clear Whey Protein Watermelon Fresca — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with Clear Whey Protein Watermelon Fresca — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Amlodipine Besylate, Benazepril interactionAmlodipine, CelecoxibConsensi
How Amlodipine, Celecoxib interacts with Clear Whey Protein Watermelon Fresca — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Amlodipine, Celecoxib interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Clear Whey Protein Watermelon Fresca — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Ammonium Chloride interactionAmphotericin, TetracyclineMysteclin-F
How Amphotericin, Tetracycline interacts with Clear Whey Protein Watermelon Fresca — through 1 ingredient. Tap an ingredient for the detail:
Whey Protein IsolateTetracycline Antibiotics Moderate
Interaction Summary
Theoretically, whey protein might decrease tetracycline absorption.
Read the full Whey Protein Isolate + Amphotericin, Tetracycline interactionAprocitentanTryvio
How Aprocitentan interacts with Clear Whey Protein Watermelon Fresca — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Aprocitentan interactionAtenololAtenix, Tenormin
How Atenolol interacts with Clear Whey Protein Watermelon Fresca — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Atenolol interactionAtenolol, ChlortalidoneAtenixCo, Tenoret 50, Totaretic
How Atenolol, Chlortalidone interacts with Clear Whey Protein Watermelon Fresca — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Atenolol, Chlortalidone interactionAtenolol, ChlorthalidoneTenoretic
How Atenolol, Chlorthalidone interacts with Clear Whey Protein Watermelon Fresca — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Atenolol, Chlorthalidone interactionAzelastine Hydrochloride, Fluticasone PropionateDymista
How Azelastine Hydrochloride, Fluticasone Propionate interacts with Clear Whey Protein Watermelon Fresca — through 1 ingredient. Tap an ingredient for the detail:
SodiumCorticosteroids Moderate
Interaction Summary
Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Read the full Sodium + Azelastine Hydrochloride, Fluticasone Propionate interactionAzilsartanEdarbi
How Azilsartan interacts with Clear Whey Protein Watermelon Fresca — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Azilsartan interactionAzilsartan, ChlorthalidoneEdarbyclor
How Azilsartan, Chlorthalidone interacts with Clear Whey Protein Watermelon Fresca — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Azilsartan, Chlorthalidone interactionBeclometasone DipropionateBecotide
How Beclometasone Dipropionate interacts with Clear Whey Protein Watermelon Fresca — through 1 ingredient. Tap an ingredient for the detail:
SodiumCorticosteroids Moderate
Interaction Summary
Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Read the full Sodium + Beclometasone Dipropionate interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Clear Whey Protein Watermelon Fresca with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Sodium
Antihypertensive Drugs
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.
Corticosteroids
Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.
Didanosine (Videx)
Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.
Lithium
Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.
Sodium Phosphates
Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.
Sodium-Containing Drugs
Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.
Tolvaptan (Samsca)
Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.
Whey Protein Isolate
Levodopa
Theoretically, whey protein might decrease levodopa absorption.
Small clinical studies show that concomitant ingestion of protein or high doses of leucine or isoleucine (100 mg/kg) and levodopa can exacerbate tremor, rigidity, and the "on-off" syndrome in patients with Parkinson disease.
Bisphosphonates
Theoretically, whey protein might reduce the absorption of bisphosphonates.
Whey protein contains minerals such as calcium that bind bisphosphonates in the gut. Advise patients to take bisphosphonates at least 30 minutes before whey protein, but preferably at a different time of day.
Quinolone Antibiotics
Theoretically, whey protein might decrease quinolone absorption.
Whey protein contains minerals, such as calcium, that can bind to quinolones in the gut. To avoid this interaction, advise patients to take oral quinolones at least 2 hours before or 4-6 hours after whey protein.
Tetracycline Antibiotics
Theoretically, whey protein might decrease tetracycline absorption.
Whey protein contains minerals, such as calcium, that bind to tetracyclines in the gut. To avoid this interaction, advise patients to take oral tetracyclines at least 2 hours before or 4-6 hours after whey protein.
Brand information
Manufacturer and brand details for Clear Whey Protein Watermelon Fresca, from the product label.
Oath Nutrition
See all Oath Nutrition products- Name
- Trove Nutrition, LLC
- Street Address
- 350 S. 850 E.
- City
- Lehi
- State
- UT
- ZipCode
- 84043
- Phone Number
- 385.557.6602
- Web Address
- oathnutrition.com
Clear Whey Protein Watermelon Fresca by Oath Nutrition: Common Questions
Does Clear Whey Protein Watermelon Fresca by Oath Nutrition interact with any medications?
How can one product interact with so many drugs?
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Will this help me build muscle or improve my workouts?
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Clear Whey Protein Watermelon Fresca is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Clear Whey Protein Watermelon Fresca’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sodium
Interacts with 205 drugsSodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets get more than enough—often too much—from...
Read the full Sodium monograph → Herb & supplement monographWhey Protein
Interacts with 53 drugsWhey protein is a high-quality, complete protein made from cow's milk that can help people meet protein needs and support muscle growth when combined with exercise. It is generally safe for...
Read the full Whey Protein monograph →Sources & How We Checked
Clear Whey Protein Watermelon Fresca's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 63 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Sodium 38 references
- Garabedian-Ruffalo SM, Ruffalo RL. Drug and nutrient interactions. Am Fam Physician 1986;33:165-74.
- Food and Drug Administration Science Background: Safety of Sodium Phosphates Oral Solution. September 17, 2001. Available at: http://www.fda.gov/cder/drug/safety/sodiumphospate.htm
- Coton T, Mallaret C, Coilliot C, Carre D, Guisset M. Severe acute ulcerated gastritis induced by salt. Presse Med 2009;38(3):499-500. PubMed
- Frings-Meuthen P, Buehlmeier J, Baecker N, et al. High sodium chloride intake exacerbates immobilization-induced bone resorption and protein losses. J Appl Physiol 2011;111(2):537-542. PubMed
- Frings-Meuthen P, Baecker N, Heer M. Low-grade metabolic acidosis may be the cause of sodium chloride-induced exaggerated bone resorption. J Bone Miner Res 2008;23(4):517-524. PubMed
- Alam S, Johnson AG. A meta-analysis of randomised controlled trials (RCT) among healthy normotensive and essential hypertensive elderly patients to determine the effect of high salt (NaCl) diet of blood pressure. J Hum Hypertens 1999;13(6):367-74.
- Boudville N, Ward S, Benaroia M, House AA. Increased sodium intake correlates with greater use of antihypertensive agents by subjects with chronic kidney disease. Am J Hypertens 2005;18(10):1300-5. PubMed
- Bennett WM. Drug interactions and consequences of sodium restriction. Am J Clin Nutr 1997;65(2 Suppl):678S-681S. PubMed
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