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Dietary supplement

Coltsfoot Non-Alcohol Ingredients & Drug Interactions

by Hawaii Pharm

Coltsfoot Non-Alcohol label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Coltsfoot Non-Alcohol against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Coltsfoot Non-Alcohol is a dietary supplement by Hawaii Pharm with 1 active ingredient. Its ingredients are commonly taken for cough, sore throat, bronchitis and congestion.Based on those ingredients, 374 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are certified organic Coltsfoot extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Coltsfoot Non-Alcohol by Hawaii Pharm

Ask about any prescription or over-the-counter medication and we check it for interactions with Coltsfoot Non-Alcohol by Hawaii Pharm — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Coltsfoot Non-Alcohol by Hawaii Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.

This product contains one active ingredient: certified organic coltsfoot extract. Coltsfoot is a plant traditionally used for respiratory and cough support.

The formulation also includes vegetable palm glycerin and water as inactive ingredients to deliver the extract.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Coltsfoot product and its label doesn't state a use — see Coltsfoot's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We don't hold effectiveness ratings for coltsfoot in our data, so we can't tell you how well it works for its intended use based on clinical evidence. That doesn't mean it doesn't work — just that the evidence isn't established in what we have on file.

The evidence, ingredient by ingredient Coltsfoot

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Here's the big issue: coltsfoot contains liver-toxic compounds called pyrrolizidine alkaloids. Chronic use of plants with these alkaloids has been linked to a serious liver condition called veno-occlusive disease, which can cause belly pain, vomiting, diarrhea, fluid buildup in the abdomen, and persistent liver enlargement.

These alkaloids can also damage your lungs. The product label advises using only certified PA-free products if you use coltsfoot at all — the risk is real enough that many practitioners recommend avoiding it altogether.

Pregnancy and breastfeeding carry extra caution here. The safety data advises against coltsfoot during pregnancy due to potential liver toxicity and harm to the baby.

It's also advised against while breastfeeding because these toxic alkaloids can pass into breast milk.

Side effects, ingredient by ingredient Coltsfoot

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Coltsfoot.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 375 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this, check with your pharmacist if you're on blood thinners or antiplatelet drugs (warfarin, aspirin, heparin, clopidogrel, ticlopidine, or others), blood pressure medications, or CYP3A4-inducing drugs like carbamazepine, phenobarbital, phenytoin, rifampin, or rifabutin. All of these have Moderate-severity interactions documented with coltsfoot.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Coltsfoot has serious liver and lung safety concerns related to toxic alkaloids it naturally contains, especially with repeated or chronic use. If you're on blood thinners, blood pressure medications, or certain anti-seizure drugs, this product poses documented interaction risks.

Talk to your pharmacist or doctor before starting — and if you've used coltsfoot products in the past, let them know.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 13, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Coltsfoot Non-Alcohol, straight from the product label.

Brand Hawaii Pharm
Barcode (UPC) 6339127907010
Net contents 4 Fluid Ounce(s); 120 mL
Market status Off market
Date entered into DSLD Dec 13, 2022
DSLD ID 268988
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Coltsfoot Non-Alcohol by Hawaii Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
20 Drop(s)
Maximum serving Sizes:
30 Drop(s)
UPC/BARCODE
6339127907010
IngredientAmount% DV
certified organic Coltsfoot extract0 NP--

Other ingredients: Vegetable Palm Glycerin, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Herbal Extract

(Tussilago farfara)

Super concentrated liquid herbal extract

General Statements

Hawaii Pharm Since 2008

Made with Aloha!

Formulation

Highest quality

Non-Alcohol

Contains no gluten, artificial colors, pesticides, preservatives, heavy metals. Non GMO.

Contains no alcohol

Dry herb/menstruum ratio: 1:3.

Description: We meticulously produced this extract according to precise standards where each herbs are individually extracted according to their distinct characteristic to ensure a broad spectrum of therapeutic plant compounds. We use a classic maceration extraction method in combination with ultrasonic extraction, so that the vitamins, minerals, alkaloids, flavonoids and other active constituents of the herbs are maintained.

Manufactured in an FDA registered facility.

Made in USA, Hawaii

Suggested/Recommended/Usage/Directions

Directions for use: Shake well before using. Take about 20-30 drops in juice, water, tea or as desired up to four times per day.

Precautions

Warnings: Keep out of the reach of children.

Not to be used during pregnancy. Consult a physician before using if nursing or taking any medications.

Do not use if you are allergic to any ingredients.

Do not use if seal is broken or missing.

Storage

Refrigerate after opening.

FDA Statement of Identity

Herbal Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

FDA Registered Facility Made in United States of America USA

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Coltsfoot Non-Alcohol by Hawaii Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Coltsfoot Non-Alcohol label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Coltsfoot Non-Alcohol by Hawaii Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size20 Drop(s) Dosage formLiquid Amounts shown are per serving.

Certified organic Coltsfoot extract

Interacts with
374 drugs
0 NP per serving

Coltsfoot is a traditional herb long used to soothe coughs and clear mucus, but solid human evidence for these uses is lacking. More importantly, the...

Certified organic Coltsfoot extract monograph & interactions

Other (inactive) ingredients: Vegetable Palm Glycerin, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Coltsfoot Non-Alcohol by Hawaii Pharm Drug Interactions

Want to check YOUR meds against Coltsfoot Non-Alcohol?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
374Drugs
374 Moderate

Ingredients driving the most interactions

certified organic Coltsfoot extract 374

Individual Drug Interactions

The ingredients in Coltsfoot Non-Alcohol interact with 374 drugs. Click any drug to see the details.

1 of the 1 ingredient in Coltsfoot Non-Alcohol interact with drugs. Each result below shows which ingredient is responsible. certified organic Coltsfoot extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Coltsfoot Non-Alcohol with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

certified organic Coltsfoot extract3 drug types · 374 drugs

Anticoagulant/Antiplatelet Drugs

Concomitant use might increase the risk of bleeding due to decreased platelet aggregation. Coltsfoot has been reported to inhibit platelet aggregation; avoid concomitant use. Some of these drugs include aspirin, clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, ticlopidine (Ticlid), warfarin (Coumadin), and others.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, excessive doses of coltsfoot may interfere with antihypertensive or cardiovascular therapy.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Inducers

Hepatotoxic pyrrolizidine alkaloids (PA) are substrates of cytochrome P450 3A4 (CYP3A4). Theoretically, drugs that induce CYP3A4 might increase the conversion of PAs to toxic metabolites. Some drugs that induce CYP3A4 include carbamazepine (Tegretol), phenobarbital, phenytoin (Dilantin), rifampin, rifabutin (Mycobutin), and others.

Likelihood Possible Evidence D
certified organic Coltsfoot extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Coltsfoot Non-Alcohol, from the product label.

Hawaii Pharm

See all Hawaii Pharm products
Name
Hawaii Pharm LLC
City
Honolulu
State
HI
ZipCode
96815
Pharmacist Counseling Corner

Coltsfoot Non-Alcohol by Hawaii Pharm: Common Questions

Does Coltsfoot Non-Alcohol by Hawaii Pharm interact with any medications?
Yes. Based on its ingredients, Coltsfoot Non-Alcohol has a known interaction with 374 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Coltsfoot Non-Alcohol contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to use long-term?
Coltsfoot's main risk is its pyrrolizidine alkaloid content, which can damage your liver and lungs with chronic use. Chronic exposure has been linked to a serious liver condition called veno-occlusive disease. The safety data advises using only certified PA-free products if at all — many practitioners recommend avoiding coltsfoot altogether.
Can I take this if I'm pregnant or breastfeeding?
No — the safety data advises against it. During pregnancy, coltsfoot poses a risk of liver toxicity and harm to the baby. While breastfeeding, toxic alkaloids from the plant can pass into your milk. Talk to your doctor or pharmacist about safe alternatives.
What are pyrrolizidine alkaloids and why should I care?
They're naturally occurring toxins in coltsfoot that can injure your liver and lungs. Your liver has to break them down, and certain medications can make that process produce even more harmful forms of these compounds. That's why CYP3A4-inducing drugs (like some anti-seizure medications) are a particular concern with this product.
What's in this besides the coltsfoot extract?
The only other ingredients are vegetable palm glycerin and water — they're there to make the liquid formulation. The active ingredient is the coltsfoot extract itself.
Does it matter that this says 'certified organic'?
Certified organic means it's grown without synthetic pesticides, but it doesn't mean it's free of pyrrolizidine alkaloids — those are naturally present in the plant. You'd need a product certified as PA-free to avoid that particular risk, which the label here does not claim.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Coltsfoot Non-Alcohol is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Coltsfoot Non-Alcohol label
Go deeper

The Full Monographs Behind Coltsfoot Non-Alcohol’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Coltsfoot

Interacts with 374 drugs

Coltsfoot is a traditional herb long used to soothe coughs and clear mucus, but solid human evidence for these uses is lacking. More importantly, the raw plant can contain liver-toxic pyrrol...

Read the full Coltsfoot monograph →
Sources

Sources & How We Checked

Coltsfoot Non-Alcohol's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Coltsfoot 8 references
  1. Roulet M, Laurini R, Rivier L, Calame A. Hepatic veno-occlusive disease in newborn infant of a woman drinking herbal tea. J Pediatr 1988;112:433-6. PubMed
  2. WHO working group. Pyrrolizidine alkaloids. Environmental Health Criteria, 80. WHO: Geneva, 1988.
  3. Chojkier M. Hepatic sinusoidal-obstruction syndrome: toxicity of pyrrolizidine alkaloids. J Hepatol 2003;39:437-46. PubMed
  4. Roeder E. Medicinal plants in Europe containing pyrrolizidine alkaloids. Pharmazie 1995;50:83-98.
  5. Wilson BE, Hobbs WN. Case report: pseudoephedrine-associated thyroid storm: thyroid hormone-catecholamine interactions. Am J Med Sci 1993;306:317-9. PubMed
  6. Wang YP, Yan J, Fu PP, Chou MW. Human liver microsomal reduction of pyrrolizidine alkaloid N-oxides to form the corresponding carcinogenic parent alkaloid. Toxicol Lett 2005;155:411-20. PubMed
  7. Hwang SB, Chang MN, Garcia ML, et al. L-652,469--a dual receptor antagonist of platelet activating factor and dihydropyridines from Tussilago farfara L. Eur J Pharmacol 1987;141:269-81. PubMed
  8. Freshour JE, Odle B, Rikhye S, Stewart DW. Coltsfoot as a potential cause of deep vein thrombosis and pulmonary embolism in a patient also consuming kava and blue vervain. J Diet Suppl 2012;9:149-54. PubMed

See these in context on the Coltsfoot monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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