Cordychi Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Cordychi against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Cordychi is a dietary supplement by Host Defense Mushrooms with 2 active ingredients. Its ingredients are commonly taken for fatigue and low energy, athletic performance and stamina, respiratory and lung support.Based on those ingredients, 502 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Reishi, Cordyceps. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Cordychi by Host Defense Mushrooms
Ask about any prescription or over-the-counter medication and we check it for interactions with Cordychi by Host Defense Mushrooms — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Cordychi by Host Defense Mushrooms
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Cordychi is a 2-ingredient powder blend of cordyceps and reishi mushroom, both traditional mushroom extracts. There are no inactive ingredients listed.
Does it work?
Not established
The evidence for what this blend actually does is thin. For cordyceps, the data rates athletic performance as possibly ineffective, and sexual dysfunction, heart rhythm problems, asthma, lung cancer, and COPD all lack enough evidence to rate.
For reishi, high cholesterol rates as possibly ineffective, and altitude sickness, Alzheimer's, and athletic performance don't have established evidence in the data we hold.
How safe is it?
Well-documented data
Both cordyceps and reishi are generally well tolerated in the short term, though evidence is limited and product quality varies widely. Cordyceps may cause diarrhea, constipation, abdominal discomfort, dry mouth, or throat discomfort—usually uncommon, and sometimes less troublesome if you take it after eating.
Reishi can cause dizziness, dry mouth, itching, nausea, rash, stomach upset, sore throat, or runny nose. There's a single case report of liver inflammation possibly linked to a cordyceps product, though it's unclear whether cordyceps or a contaminant was responsible.
Neither ingredient has enough safety data for pregnancy or breastfeeding, so the safety notes advise against use in both.
Meds to double-check
Moderate interaction found
Before taking this product, check with your doctor or pharmacist if you're on blood thinners or antiplatelet drugs, blood pressure medications, diabetes medications, or immunosuppressants. Cordyceps and reishi both interact moderately with blood thinners; reishi also moderately interacts with blood pressure and diabetes drugs; and cordyceps moderately interacts with immune-suppressing drugs.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
Cordychi is a two-mushroom blend with sparse evidence for its intended uses and multiple interactions with blood thinners, blood pressure drugs, diabetes drugs, and immunosuppressants. If you take any prescription medications—especially those—talk it over with your doctor or pharmacist before starting.
Pregnant or breastfeeding? The data isn't there; check with your healthcare provider first.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Cordychi, straight from the product label.
| Brand | Host Defense Mushrooms |
|---|---|
| Barcode (UPC) | 633422694849 |
| Net contents | 3.5 Ounce(s); 100 Gram(s) |
| Market status | On market |
| Date entered into DSLD | Jul 25, 2024 |
| DSLD ID | 312242 |
| Product type | Botanical |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Organic, Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Cordychi by Host Defense Mushrooms, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 5 Calorie(s) | -- |
| Total Carbohydrates | 1 Gram(s) | 1% |
| Cordyceps | 750 mg | -- |
| Reishi | 750 mg | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Powered by Mushroom Mycelium Chrodychi is a synergistic blend of equal parts Cordyceps and Reishi that supports both sustained energy to keep you going and stress reduction to help you relax. Sustainably grown in the USA under the supervision of Paul Stamets, our mushroom mycelium is cultured on organic brown rice. This bioavailable powder has a mild flavor and can be mixed in your favorite recipe.
Cordyceps Reishi Mushroom Mycelium Powder
Suggested/Recommended/Usage/Directions
Directions: Adults take 1/2 tsp. 1-3 times per day.
Precautions
Caution: If you have a medical condition, are taking medications, or are pregnant or breastfeeding, consult a healthcare professional before using this product.
Keep out of reach of children.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Seals/Symbols
Eco Packaging USDA Organic
Washington State Department of Agriculture Organic Program Certified Organic
Formulation
Vegan
Gluten Free Non-GMO
USDA Organic
Supports Stress & Fatigue Reduction
Certified Organic by the WSDA
FDA Statement of Identity
Dietary Supplement
General Statements
Paul Stamets Fungi Perfecti, LLC
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Cordychi by Host Defense Mushrooms label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Cordychi by Host Defense Mushrooms
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1.5 Gram(s) Dosage formPowder Servings per container66 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Cordyceps
Interacts with249 drugs
Cordyceps is a fungus used in traditional Chinese medicine for energy, exercise performance, and lung and immune support. Human research is limited an...
Cordyceps monograph & interactionsReishi
Interacts with375 drugs
Reishi is a traditional Asian mushroom widely used to support the immune system and overall wellness. Human evidence for most of its claimed benefits...
Reishi monograph & interactionsCordychi by Host Defense Mushrooms Drug Interactions
HelloPharmacist Interaction Report
Host Defense Mushrooms Cordychi contains cordyceps and reishi, both of which interact with several medication types.
The most serious concern is a moderate-severity interaction: cordyceps may increase bleeding risk when combined with blood thinners or antiplatelet drugs (like warfarin or aspirin), though this hasn't been reported in humans yet.
Read the full breakdown — every affected drug type, severity by severity
Reishi carries its own moderate interactions. High doses may also raise bleeding risk with blood thinners—though lower doses (1.5 grams daily) appear safe.
Reishi may lower blood pressure, so combining it with blood pressure medications could push your pressure too low. It may also affect blood sugar, which could add to the effect of diabetes medications and theoretically tip your glucose too low.
Cordyceps also interacts moderately with immunosuppressants (drugs that calm your immune system after transplant or for autoimmune conditions), since it stimulates immunity and might interfere with those drugs working as intended. There's a minor theoretical interaction between cordyceps and testosterone.
Altogether, these interactions span 502 individual medications. Check your exact prescriptions using the search tool on this page before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Cordychi?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Cordychi interact with 502 drugs. Click any drug to see the details.
2 of the 2 ingredients in Cordychi interact with drugs. Each result below shows which ingredient is responsible. Reishi Cordyceps
Dapagliflozin Propanediol, Saxagliptin HydrochlorideQtern
How Dapagliflozin Propanediol, Saxagliptin Hydrochloride interacts with Cordychi — through 1 ingredient. Tap an ingredient for the detail:
ReishiAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Read the full Reishi + Dapagliflozin Propanediol, Saxagliptin Hydrochloride interactionDapagliflozin, Metformin Hydrochloride, Saxagliptin HydrochlorideQternmet XR
How Dapagliflozin, Metformin Hydrochloride, Saxagliptin Hydrochloride interacts with Cordychi — through 1 ingredient. Tap an ingredient for the detail:
ReishiAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Read the full Reishi + Dapagliflozin, Metformin Hydrochloride, Saxagliptin Hydrochloride interactionDasiglucagon HydrochlorideZegalogue
How Dasiglucagon Hydrochloride interacts with Cordychi — through 1 ingredient. Tap an ingredient for the detail:
ReishiAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Read the full Reishi + Dasiglucagon Hydrochloride interactionDefibrotide SodiumDefitelio
How Defibrotide Sodium interacts with Cordychi — through 2 ingredients. Tap an ingredient for the detail:
ReishiAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi + Defibrotide Sodium interactionCordycepsAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Cordyceps + Defibrotide Sodium interactionDeflazacortEmflaza
How Deflazacort interacts with Cordychi — through 1 ingredient. Tap an ingredient for the detail:
CordycepsImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Read the full Cordyceps + Deflazacort interactionDenosumabProlia, XGEVA
How Denosumab interacts with Cordychi — through 1 ingredient. Tap an ingredient for the detail:
CordycepsImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Read the full Cordyceps + Denosumab interactionDeserpidineHarmonyl
How Deserpidine interacts with Cordychi — through 1 ingredient. Tap an ingredient for the detail:
ReishiAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Read the full Reishi + Deserpidine interactionDeserpidine, HydrochlorothiazideOreticyl, Oreticyl Forte
How Deserpidine, Hydrochlorothiazide interacts with Cordychi — through 1 ingredient. Tap an ingredient for the detail:
ReishiAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Read the full Reishi + Deserpidine, Hydrochlorothiazide interactionDeserpidine, MethyclothiazideEnduronyl, Enduronyl Forte
How Deserpidine, Methyclothiazide interacts with Cordychi — through 1 ingredient. Tap an ingredient for the detail:
ReishiAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Read the full Reishi + Deserpidine, Methyclothiazide interactionDeucravacitinibSotyktu
How Deucravacitinib interacts with Cordychi — through 1 ingredient. Tap an ingredient for the detail:
CordycepsImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Read the full Cordyceps + Deucravacitinib interactionDexamethasoneDecadron, Dexone, Dextenza, Dexycu, Hemady, Hexadrol +1 more
How Dexamethasone interacts with Cordychi — through 1 ingredient. Tap an ingredient for the detail:
CordycepsImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Read the full Cordyceps + Dexamethasone interactionDiclofenacZorvolex
How Diclofenac interacts with Cordychi — through 2 ingredients. Tap an ingredient for the detail:
CordycepsAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Cordyceps + Diclofenac interactionReishiAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi + Diclofenac interactionDiclofenac PotassiumCambia, Cataflam, Cataflam IR, Voltaren Rapide, Voltarol Rapid
How Diclofenac Potassium interacts with Cordychi — through 2 ingredients. Tap an ingredient for the detail:
CordycepsAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Cordyceps + Diclofenac Potassium interactionReishiAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi + Diclofenac Potassium interactionDiclofenac SodiumAcoflam, Acoflam 75 SR, Acoflam Retard, Defenac, Defenac Retard, Defenac SR +40 more
How Diclofenac Sodium interacts with Cordychi — through 2 ingredients. Tap an ingredient for the detail:
ReishiAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi + Diclofenac Sodium interactionCordycepsAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Cordyceps + Diclofenac Sodium interactionDiclofenac Sodium, MisoprostolArthrotec 50, Arthrotec 75
How Diclofenac Sodium, Misoprostol interacts with Cordychi — through 2 ingredients. Tap an ingredient for the detail:
CordycepsAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Cordyceps + Diclofenac Sodium, Misoprostol interactionReishiAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi + Diclofenac Sodium, Misoprostol interactionDiclofenac EpolamineFlector, Licart
How Diclofenac Epolamine interacts with Cordychi — through 2 ingredients. Tap an ingredient for the detail:
ReishiAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi + Diclofenac Epolamine interactionCordycepsAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Cordyceps + Diclofenac Epolamine interactionDicumarolDicumarol
How Dicumarol interacts with Cordychi — through 2 ingredients. Tap an ingredient for the detail:
ReishiAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi + Dicumarol interactionCordycepsAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Cordyceps + Dicumarol interactionDiltiazemAdizem-SR, Adizem-XL, Angitil SR, Angitil XL, Calcicard CR, Cardizem +23 more
How Diltiazem interacts with Cordychi — through 1 ingredient. Tap an ingredient for the detail:
ReishiAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Read the full Reishi + Diltiazem interactionDiltiazem, EnalaprilTeczem
How Diltiazem, Enalapril interacts with Cordychi — through 1 ingredient. Tap an ingredient for the detail:
ReishiAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Read the full Reishi + Diltiazem, Enalapril interactionDiphenhydramine Hydrochloride, Naproxen SodiumAleve PM
How Diphenhydramine Hydrochloride, Naproxen Sodium interacts with Cordychi — through 2 ingredients. Tap an ingredient for the detail:
CordycepsAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Cordyceps + Diphenhydramine Hydrochloride, Naproxen Sodium interactionReishiAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi + Diphenhydramine Hydrochloride, Naproxen Sodium interactionDipyridamoleDipyridamole, Persantin, Persantin Injection, Persantin Retard, Persantine
How Dipyridamole interacts with Cordychi — through 2 ingredients. Tap an ingredient for the detail:
ReishiAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi + Dipyridamole interactionCordycepsAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Cordyceps + Dipyridamole interactionDiroximel FumarateVumerity
How Diroximel Fumarate interacts with Cordychi — through 1 ingredient. Tap an ingredient for the detail:
CordycepsImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Read the full Cordyceps + Diroximel Fumarate interactionDoxazosin MesylateCardura
How Doxazosin Mesylate interacts with Cordychi — through 1 ingredient. Tap an ingredient for the detail:
ReishiAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Read the full Reishi + Doxazosin Mesylate interactionDulaglutideTrulicity
How Dulaglutide interacts with Cordychi — through 1 ingredient. Tap an ingredient for the detail:
ReishiAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Read the full Reishi + Dulaglutide interactionDurvalumabImfinzi
How Durvalumab interacts with Cordychi — through 1 ingredient. Tap an ingredient for the detail:
CordycepsImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Read the full Cordyceps + Durvalumab interactionEculizumabSoliris
How Eculizumab interacts with Cordychi — through 1 ingredient. Tap an ingredient for the detail:
CordycepsImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Read the full Cordyceps + Eculizumab interactionEdoxabanSavaysa
How Edoxaban interacts with Cordychi — through 2 ingredients. Tap an ingredient for the detail:
CordycepsAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Cordyceps + Edoxaban interactionReishiAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi + Edoxaban interactionEfalizumabRaptiva
How Efalizumab interacts with Cordychi — through 1 ingredient. Tap an ingredient for the detail:
CordycepsImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Read the full Cordyceps + Efalizumab interactionEffientPrasugrel
How Effient interacts with Cordychi — through 2 ingredients. Tap an ingredient for the detail:
CordycepsAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Cordyceps + Effient interactionReishiAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi + Effient interactionEfgartigimod Alfa-fcabVyvgart
How Efgartigimod Alfa-fcab interacts with Cordychi — through 1 ingredient. Tap an ingredient for the detail:
CordycepsImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Read the full Cordyceps + Efgartigimod Alfa-fcab interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Cordychi with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Reishi
Anticoagulant/Antiplatelet Drugs
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
A dose of 1.5 grams daily of reishi mushroom does not seem to decrease platelet aggregation, but a higher dose of 3 grams daily does.
Antidiabetes Drugs
Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Animal research suggests that reishi mushroom decreases blood sugar. However, in patients with type 2 diabetes, taking reishi mushroom does not reduce fasting glucose levels, and its effects on glycated hemoglobin are inconsistent.
Antihypertensive Drugs
Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Reishi mushroom has shown hypotensive activity in animal research. Clinical evidence suggests that reishi mushroom reduces blood pressure in some, but not all, patients with hypertension.
Cordyceps
Anticoagulant/Antiplatelet Drugs
Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
In vitro and animal research suggests that cordyceps extract inhibits platelet aggregation and function. However, this interaction has not been reported in humans.
Immunosuppressants
Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Animal and in vitro research suggests that cordyceps stimulates the immune system. However, limited clinical research suggests that taking cordyceps may lower the necessary therapeutic dose of the immunosuppressant cyclosporine, which suggests that cordyceps may have an immunosuppressive effect.
Testosterone
Theoretically, concurrent use of cordyceps and testosterone might have additive effects.
Animal research suggests that cordyceps can increase testosterone levels. The clinical significance of this finding is unclear.
Brand information
Manufacturer and brand details for Cordychi, from the product label.
Host Defense Mushrooms
See all Host Defense Mushrooms products- Name
- Fungi Perfecti, LLC
- Street Address
- PO Box 7634
- City
- Olympia
- State
- WA
- ZipCode
- 98507
- Phone Number
- 877-504-6926
- Web Address
- Hostdefense.com
Cordychi by Host Defense Mushrooms: Common Questions
Does Cordychi by Host Defense Mushrooms interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take Cordychi if I'm on a blood thinner like warfarin or aspirin?
What side effects might I notice?
Is this safe during pregnancy or breastfeeding?
Does Cordychi actually work for athletic performance?
I'm on blood pressure medication. Is Cordychi okay?
What's in this powder besides the mushrooms?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Cordychi is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Cordychi’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Cordyceps
Interacts with 249 drugsCordyceps is a fungus used in traditional Chinese medicine for energy, exercise performance, and lung and immune support. Human research is limited and mostly low quality, so its benefits ar...
Read the full Cordyceps monograph → Herb & supplement monographReishi Mushroom
Interacts with 375 drugsReishi is a traditional Asian mushroom widely used to support the immune system and overall wellness. Human evidence for most of its claimed benefits is limited or low-quality, so it should...
Read the full Reishi Mushroom monograph →Sources & How We Checked
Cordychi's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 31 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Cordyceps 14 references
- Zhu JS, Halpern GM, Jones K. The scientific rediscovery of an ancient Chinese herbal medicine: Cordyceps sinensis: part I. J Altern Complement Med 1998;4:289-303.
- Zhu JS, Halpern GM, Jones K. The scientific rediscovery of a precious ancient Chinese herbal regimen: Cordyceps sinensis: part II. J Altern Complement Med 1998;4:429-57.
- Chen YJ, Shiao MS, Lee SS, Wang SY. Effect of Cordyceps sinensis on the proliferation and differentiation of human leukemic U937 cells. Life Sci 1997;60:2349-59. PubMed
- Zhao Y. [Inhibitory effects of alcoholic extract of Cordyceps sinensis on abdominal aortic thrombus formation in rabbits]. Chung Hua I Hsueh Tsa Chih (Taipei) 1991;71:612-5, 42.
- Chen GZ, Chen GL, Sun T, et al. Effects of Cordyceps sinensis on murine T lymphocyte subsets. Chin Med J (English) 1991;104:4-8.
- Zhu XY, Yu HY. [Immunosuppressive effect of cultured Cordyceps sinensis on cellular immune response]. Chung Hsi I Chieh Ho Tsa Chih 1990;10:485-7, 454.
- Hsu, C. C., Huang, Y. L., Tsai, S. J., Sheu, C. C., and Huang, B. M. In vivo and in vitro stimulatory effects of Cordyceps sinensis on testosterone production in mouse Leydig cells. Life Sci 9-5-2003;73(16):2127-2136. PubMed
- Ikumoto, T., Sasaki, S., Namba, H., Toyama, R., Moritoki, H., and Mouri, T. [Physiologically active compounds in the extracts from tochukaso and cultured mycelia of Cordyceps and Isaria]. Yakugaku Zasshi 1991;111(9):504-509. PubMed
- Wu, T. N., Yang, K. C., Wang, C. M., Lai, J. S., Ko, K. N., Chang, P. Y., and Liou, S. H. Lead poisoning caused by contaminated Cordyceps, a Chinese herbal medicine: two case reports. Sci.Total Environ. 4-5-1996;182(1-3):193-195. PubMed
- Hong T, Zhang M, Fan J. Cordyceps sinensis (a traditional Chinese medicine) for kidney transplant recipients (Review). Cochrane Database Syst Rev. 2015;(10):CD009698. doi: 10.1002/14651858.CD009698.pub2.
- Zhang HW, Lin ZX, Tung YS, Kwan TH, Mok CK, Leung C, Chan LS. Cordyceps sinensis (a traditional Chinese medicine) for treating chronic kidney disease (Review). Cochrane Database Syst Rev. 2014;(12):CD008353. doi: 10.1002/14651858.CD008353.pub2. PubMed
- Bee Yean O, Zoriah A. Efficacy of Cordyceps sinensis as an adjunctive treatment in hemodialysis patients: a systematic review and Meta-analysis. J Tradit Chin Med. 2019;39(1):1-14.
- Thurian D, Montani M, Stickel F. Drug-induced, mixed-type hepatitis following ingestion of Cordyceps sinensis. Int J Clin Pharmacol Ther 2022;60(2):115-120. PubMed
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