Curing Pills Ingredients & Drug Interactions
by Plum Flower
What is this page for?
First and foremost: checking Curing Pills against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Curing Pills is a dietary supplement by Plum Flower with 15 active ingredients. Its ingredients are commonly taken for anxiety and stress, sleep problems, digestive upset.Based on those ingredients, 1,274 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Atractylodes lancea Rhizome Extract, Citrus reticulata Peel Extract, Pueraria lobata root extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Curing Pills by Plum Flower
Ask about any prescription or over-the-counter medication and we check it for interactions with Curing Pills by Plum Flower — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Curing Pills by Plum Flower
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Curing Pills is a 15-ingredient herbal blend in capsule form. The active ingredients include magnolia bark (traditionally used for gingivitis, though evidence is limited), Job's tears seed, poria mushroom, kudzu root, atractylodes rhizome, chrysanthemum flower, Japanese mint, and several others — plus tangerine peel extract.
The formula also contains inactive ingredients such as hypromellose (a capsule material), maltose, magnesium silicate, activated charcoal, and china wax.
Does it work?
Moderate evidence
The evidence supporting individual ingredients in this blend is sparse. Magnolia bark is possibly effective for gingivitis, but the data on the other herbs — Job's tears, poria mushroom, kudzu, atractylodes, chrysanthemum, and the rest — remains insufficient to rate their effectiveness for any condition.
We hold no effectiveness ratings for patchouli, angelica, foxtail millet, trichosanthes, or fermented mass. Because this is a blend and the dose of each ingredient is not specified, we cannot estimate how effective the combination might be for any particular use.
How safe is it?
Well-documented data
Magnolia bark and poria mushroom are generally well tolerated orally, though long-term safety data are limited. Magnolia is unsafe in pregnancy and should be avoided while breastfeeding.
Poria mushroom should also be avoided in pregnancy and during breastfeeding. Kudzu is generally well tolerated short-term but long-term safety is unclear; it too should be avoided in pregnancy and breastfeeding.
Atractylodes may be possibly unsafe in pregnancy. Chrysanthemum can cause allergic reactions in sensitive people and should be avoided unless your doctor approves it in pregnancy; breastfeeding safety is not established.
Japanese mint essential oil can be irritating; food amounts are likely fine but concentrated products need doctor clearance, and the oil should be kept off the chest while nursing. Tangerine extract has not been thoroughly evaluated for safety.
Meds to double-check
Moderate interaction found
Before taking this product, double-check any anticoagulant or antiplatelet drugs (blood thinners like warfarin), antidiabetes medications, CNS depressants (sedatives, sleep aids), aromatase inhibitors, theophylline, dextromethorphan, chlorzoxazone, diltiazem, anticholinergic drugs, and cholinergic drugs. These are the drug categories with documented Moderate interactions in this blend.
Use the medication checker below to confirm your exact prescriptions.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
This is a traditional herbal blend with limited evidence on how well it works. If you take any blood thinners, drugs for diabetes, sedatives, or heart medications, check your specific medications with the tool on this page before starting.
Pregnant people and those breastfeeding should talk with their pharmacist or doctor first, as several ingredients carry cautions. If you have a known allergy to plants in the daisy or mint families, be cautious.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 11 of 15 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Curing Pills, straight from the product label.
| Brand | Plum Flower |
|---|---|
| Barcode (UPC) | 739934839669 |
| Net contents | 30 Veggie Capsule(s); 0.48 Ounce(s); 13.6 Gram(s) |
| Market status | On market |
| Date entered into DSLD | Jun 25, 2025 |
| DSLD ID | 331211 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Curing Pills by Plum Flower, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Extract Blend | 1074 mg | -- |
| Magnolia officinalis Bark Extract | 0 NP | -- |
| Citrus reticulata Peel Extract | 0 NP | -- |
| Poria cocos Sclerotium Extract | 0 NP | -- |
| Aucklandia lappa Root Extract | 0 NP | -- |
| Coix lacryma jobi Seed Extract | 0 NP | -- |
| Pogostemon cablin Herb Extract | 0 NP | -- |
| Angelica dahurica Root Extract | 0 NP | -- |
| Pueraria lobata root extract | 0 NP | -- |
| Setaria italica Fruit Extract | 0 NP | -- |
| Trichosanthes kirilowii Root Extract | 0 NP | -- |
| Chrysanthemum morifolium Flower Extract | 0 NP | -- |
| Gastrodia elata Rhizome Extract | 0 NP | -- |
| Mentha haplocalyx herb extract | 0 NP | -- |
| Atractylodes lancea Rhizome Extract | 0 NP | -- |
| Massa fermenta Extract | 0 NP | -- |
Other ingredients: Hypromellose, Water, Maltose, Magnesium Silicate, Hydrated, Activated Carbon, China Wax
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
GMP Quality Curing Pills in Veggie capsules
Plum Flower Guarantee
US owned & operated since 1969. Made in China in partnership with the award-winning Lanzhou Foci Pharmaceutical Co. Ltd.
FDA Statement of Identity
Herbal Supplement
Precautions
Contains Wheat, Apricot kernel (*processed with wheat bran)
Caution during pregnancy
Keep out of reach of children
Suggested/Recommended/Usage/Directions
Take 3 capsules 3 times daily or as directed by your health care practitioner
Seals/Symbols
Sourced Sustainably FDA Registered cGMP Compliant Made at a cGMP Certified Facility Lab Tested Quality Verified Species Verified
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Curing Pills by Plum Flower label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Curing Pills by Plum Flower
These are the 15 active ingredients this product is made of. Select any to open its full monograph.
Serving size3 Capsule(s) Dosage formCapsule Servings per container10 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Extract Blend
- › Magnolia officinalis Bark Extract
- › Citrus reticulata Peel Extract
- › Poria cocos Sclerotium Extract
- › Aucklandia lappa Root Extract
- › Coix lacryma jobi Seed Extract
- › Pogostemon cablin Herb Extract
- › Angelica dahurica Root Extract
- › Pueraria lobata root extract
- › Setaria italica Fruit Extract
- › Trichosanthes kirilowii Root Extract
- › Chrysanthemum morifolium Flower Extract
- › Gastrodia elata Rhizome Extract
- › Mentha haplocalyx herb extract
- › Atractylodes lancea Rhizome Extract
- › Massa fermenta Extract
Other (inactive) ingredients: Hypromellose, Water, Maltose, Magnesium Silicate, Hydrated, Activated Carbon, China Wax. These complete the product’s ingredient list but are not active constituents.
Curing Pills by Plum Flower Drug Interactions
HelloPharmacist Interaction Report
Plum Flower's Curing Pills contains 15 ingredients, several of which interact with medications.
The most serious concern is kudzu (Pueraria lobata root extract), which carries multiple Moderate-severity interactions, including with anticoagulant and antiplatelet drugs (blood thinners) — kudzu isoflavones have antiplatelet activity that could raise bleeding risk.
Read the full breakdown — every affected drug type, severity by severity
Other ingredients with Moderate-severity interactions are magnolia bark (CNS depressants like sedatives, and blood thinners), Job's tears seed (antidiabetes drugs, theophylline, dextromethorphan, chlorzoxazone, and diltiazem), atractylodes rhizome (blood thinners, aromatase inhibitors, and hexobarbital), and poria mushroom (CNS depressants, anticholinergic drugs, and cholinergic drugs). Tangerine peel has Minor interactions with CYP3A4 substrates and midazolam specifically, though human evidence suggests the effect is small.
We could not check several ingredients — patchouli herb, angelica root, foxtail millet fruit, trichosanthes root, and fermented mass — as we hold no interaction data for them. Chrysanthemum flower and Japanese mint were checked and show no documented interactions.
Altogether, these interactions span 1,253 individual medications.
Use the medication checker on this page to verify your exact drugs before starting.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Curing Pills?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Curing Pills interact with 1,274 drugs. Click any drug to see the details.
8 of the 15 ingredients in Curing Pills interact with drugs. Each result below shows which ingredient is responsible. Atractylodes lancea Rhizome Extract Citrus reticulata Peel Extract Pueraria lobata root extract Poria cocos Sclerotium Extract Magnolia officinalis Bark Extract Angelica dahurica Root Extract Coix lacryma jobi Seed Extract Trichosanthes kirilowii Root Extract
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Curing Pills — through 1 ingredient. Tap an ingredient for the detail:
Pueraria Lobata Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract + 6-mercaptopurine interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Curing Pills — through 1 ingredient. Tap an ingredient for the detail:
Pueraria Lobata Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Curing Pills — through 1 ingredient. Tap an ingredient for the detail:
Pueraria Lobata Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract + Abacavir, Lamivudine interactionAbciximabReoPro
How Abciximab interacts with Curing Pills — through 3 ingredients. Tap an ingredient for the detail:
Magnolia Officinalis Bark ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, magnolia might have additive effects and increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Magnolia Officinalis Bark Extract + Abciximab interactionPueraria Lobata Root ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, kudzu may increase the risk of bleeding if used with antiplatelet or anticoagulant drugs.
Read the full Pueraria Lobata Root Extract + Abciximab interactionAtractylodes Lancea Rhizome ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, atractylodes might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Read the full Atractylodes Lancea Rhizome Extract + Abciximab interactionAbiraterone
How Abiraterone interacts with Curing Pills — through 3 ingredients. Tap an ingredient for the detail:
Pueraria Lobata Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract + Abiraterone interactionCitrus Reticulata Peel ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Citrus Reticulata Peel Extract + Abiraterone interactionAtractylodes Lancea Rhizome ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, atractylodes might increase the levels of CYP3A4 substrates.
Read the full Atractylodes Lancea Rhizome Extract + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Curing Pills — through 3 ingredients. Tap an ingredient for the detail:
Pueraria Lobata Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract + Abiraterone Acetate interactionCitrus Reticulata Peel ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Citrus Reticulata Peel Extract + Abiraterone Acetate interactionAtractylodes Lancea Rhizome ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, atractylodes might increase the levels of CYP3A4 substrates.
Read the full Atractylodes Lancea Rhizome Extract + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Curing Pills — through 3 ingredients. Tap an ingredient for the detail:
Atractylodes Lancea Rhizome ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, atractylodes might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Read the full Atractylodes Lancea Rhizome Extract + Abrocitinib interactionPueraria Lobata Root ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, kudzu may increase the risk of bleeding if used with antiplatelet or anticoagulant drugs.
Read the full Pueraria Lobata Root Extract + Abrocitinib interactionMagnolia Officinalis Bark ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, magnolia might have additive effects and increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Magnolia Officinalis Bark Extract + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Curing Pills — through 3 ingredients. Tap an ingredient for the detail:
Coix Lacryma Jobi Seed ExtractAntidiabetes Drugs Moderate
Interaction Summary
Preliminary evidence shows that constituents of Job's tears might have hypoglycemic effects.
Read the full Coix Lacryma Jobi Seed Extract + Acarbose interactionTrichosanthes Kirilowii Root ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Chinese cucumber with antidiabetic drugs may have additive effects and adverse effects.
Read the full Trichosanthes Kirilowii Root Extract + Acarbose interactionPueraria Lobata Root ExtractAntidiabetes Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking kudzu with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Pueraria Lobata Root Extract + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Curing Pills — through 1 ingredient. Tap an ingredient for the detail:
Pueraria Lobata Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Curing Pills — through 3 ingredients. Tap an ingredient for the detail:
Magnolia Officinalis Bark ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, magnolia might have additive effects and increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Magnolia Officinalis Bark Extract + Acenocoumarol interactionPueraria Lobata Root ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, kudzu may increase the risk of bleeding if used with antiplatelet or anticoagulant drugs.
Read the full Pueraria Lobata Root Extract + Acenocoumarol interactionAtractylodes Lancea Rhizome ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, atractylodes might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Read the full Atractylodes Lancea Rhizome Extract + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Curing Pills — through 2 ingredients. Tap an ingredient for the detail:
Poria Cocos Sclerotium ExtractAnticholinergic Drugs, Cns Depressants Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Cocos Sclerotium Extract + Acepromazine interactionMagnolia Officinalis Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Officinalis Bark Extract + Acepromazine interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Curing Pills — through 3 ingredients. Tap an ingredient for the detail:
Pueraria Lobata Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract + Acetaminophen interactionAngelica Dahurica Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
In vitro research shows that ashitaba extract inhibits cytochrome P450 (CYP) 1A2.
Read the full Angelica Dahurica Root Extract + Acetaminophen interactionAtractylodes Lancea Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodes Lancea Rhizome Extract + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Curing Pills — through 4 ingredients. Tap an ingredient for the detail:
Angelica Dahurica Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
In vitro research shows that ashitaba extract inhibits cytochrome P450 (CYP) 1A2.
Read the full Angelica Dahurica Root Extract + Acetaminophen, Aspirin interactionAtractylodes Lancea Rhizome ExtractAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, atractylodes might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Read the full Atractylodes Lancea Rhizome Extract + Acetaminophen, Aspirin interactionPueraria Lobata Root ExtractHepatotoxic Drugs, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract + Acetaminophen, Aspirin interactionMagnolia Officinalis Bark ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, magnolia might have additive effects and increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Magnolia Officinalis Bark Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Curing Pills — through 5 ingredients. Tap an ingredient for the detail:
Magnolia Officinalis Bark ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, magnolia might have additive effects and increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Magnolia Officinalis Bark Extract + Acetaminophen, Aspirin, Caffeine interactionPueraria Lobata Root ExtractHepatotoxic Drugs, Caffeine +1 Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract + Acetaminophen, Aspirin, Caffeine interactionAtractylodes Lancea Rhizome ExtractAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, atractylodes might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Read the full Atractylodes Lancea Rhizome Extract + Acetaminophen, Aspirin, Caffeine interactionAngelica Dahurica Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
In vitro research shows that ashitaba extract inhibits cytochrome P450 (CYP) 1A2.
Read the full Angelica Dahurica Root Extract + Acetaminophen, Aspirin, Caffeine interactionCitrus Reticulata Peel ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Citrus Reticulata Peel Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Curing Pills — through 3 ingredients. Tap an ingredient for the detail:
Angelica Dahurica Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
In vitro research shows that ashitaba extract inhibits cytochrome P450 (CYP) 1A2.
Read the full Angelica Dahurica Root Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionPueraria Lobata Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAtractylodes Lancea Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodes Lancea Rhizome Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Curing Pills — through 3 ingredients. Tap an ingredient for the detail:
Pueraria Lobata Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract + Acetaminophen, Butalbital interactionAngelica Dahurica Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
In vitro research shows that ashitaba extract inhibits cytochrome P450 (CYP) 1A2.
Read the full Angelica Dahurica Root Extract + Acetaminophen, Butalbital interactionAtractylodes Lancea Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodes Lancea Rhizome Extract + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Curing Pills — through 4 ingredients. Tap an ingredient for the detail:
Angelica Dahurica Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
In vitro research shows that ashitaba extract inhibits cytochrome P450 (CYP) 1A2.
Read the full Angelica Dahurica Root Extract + Acetaminophen, Butalbital, Caffeine interactionPueraria Lobata Root ExtractHepatotoxic Drugs, Caffeine Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract + Acetaminophen, Butalbital, Caffeine interactionAtractylodes Lancea Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodes Lancea Rhizome Extract + Acetaminophen, Butalbital, Caffeine interactionCitrus Reticulata Peel ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Citrus Reticulata Peel Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Curing Pills — through 6 ingredients. Tap an ingredient for the detail:
Pueraria Lobata Root ExtractCaffeine, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking kudzu with caffeine might increase levels of caffeine.
Read the full Pueraria Lobata Root Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionMagnolia Officinalis Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Officinalis Bark Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionPoria Cocos Sclerotium ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAngelica Dahurica Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
In vitro research shows that ashitaba extract inhibits cytochrome P450 (CYP) 1A2.
Read the full Angelica Dahurica Root Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAtractylodes Lancea Rhizome ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, atractylodes might increase the levels of CYP3A4 substrates.
Read the full Atractylodes Lancea Rhizome Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionCitrus Reticulata Peel ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Citrus Reticulata Peel Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Curing Pills — through 5 ingredients. Tap an ingredient for the detail:
Angelica Dahurica Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
In vitro research shows that ashitaba extract inhibits cytochrome P450 (CYP) 1A2.
Read the full Angelica Dahurica Root Extract + Acetaminophen, Butalbital, Codeine interactionPoria Cocos Sclerotium ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Butalbital, Codeine interactionPueraria Lobata Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract + Acetaminophen, Butalbital, Codeine interactionMagnolia Officinalis Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Officinalis Bark Extract + Acetaminophen, Butalbital, Codeine interactionAtractylodes Lancea Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodes Lancea Rhizome Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Curing Pills — through 5 ingredients. Tap an ingredient for the detail:
Magnolia Officinalis Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Officinalis Bark Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionPueraria Lobata Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionPoria Cocos Sclerotium ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAngelica Dahurica Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
In vitro research shows that ashitaba extract inhibits cytochrome P450 (CYP) 1A2.
Read the full Angelica Dahurica Root Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAtractylodes Lancea Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodes Lancea Rhizome Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Curing Pills — through 6 ingredients. Tap an ingredient for the detail:
Angelica Dahurica Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
In vitro research shows that ashitaba extract inhibits cytochrome P450 (CYP) 1A2.
Read the full Angelica Dahurica Root Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionPoria Cocos Sclerotium ExtractCns Depressants, Anticholinergic Drugs Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionPueraria Lobata Root ExtractCaffeine, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking kudzu with caffeine might increase levels of caffeine.
Read the full Pueraria Lobata Root Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionMagnolia Officinalis Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Officinalis Bark Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAtractylodes Lancea Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodes Lancea Rhizome Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionCitrus Reticulata Peel ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Citrus Reticulata Peel Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Curing Pills — through 6 ingredients. Tap an ingredient for the detail:
Poria Cocos Sclerotium ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Caffeine, Codeine interactionMagnolia Officinalis Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Officinalis Bark Extract + Acetaminophen, Caffeine, Codeine interactionPueraria Lobata Root ExtractCaffeine, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking kudzu with caffeine might increase levels of caffeine.
Read the full Pueraria Lobata Root Extract + Acetaminophen, Caffeine, Codeine interactionAngelica Dahurica Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
In vitro research shows that ashitaba extract inhibits cytochrome P450 (CYP) 1A2.
Read the full Angelica Dahurica Root Extract + Acetaminophen, Caffeine, Codeine interactionCitrus Reticulata Peel ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Citrus Reticulata Peel Extract + Acetaminophen, Caffeine, Codeine interactionAtractylodes Lancea Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodes Lancea Rhizome Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Curing Pills — through 6 ingredients. Tap an ingredient for the detail:
Angelica Dahurica Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
In vitro research shows that ashitaba extract inhibits cytochrome P450 (CYP) 1A2.
Read the full Angelica Dahurica Root Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionPueraria Lobata Root ExtractHepatotoxic Drugs, Caffeine Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionPoria Cocos Sclerotium ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionMagnolia Officinalis Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Officinalis Bark Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAtractylodes Lancea Rhizome ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, atractylodes might increase the levels of CYP3A4 substrates.
Read the full Atractylodes Lancea Rhizome Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionCitrus Reticulata Peel ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Citrus Reticulata Peel Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Curing Pills — through 6 ingredients. Tap an ingredient for the detail:
Magnolia Officinalis Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Officinalis Bark Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionPoria Cocos Sclerotium ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionPueraria Lobata Root ExtractHepatotoxic Drugs, Caffeine Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAngelica Dahurica Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
In vitro research shows that ashitaba extract inhibits cytochrome P450 (CYP) 1A2.
Read the full Angelica Dahurica Root Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAtractylodes Lancea Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodes Lancea Rhizome Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionCitrus Reticulata Peel ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Citrus Reticulata Peel Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Curing Pills — through 4 ingredients. Tap an ingredient for the detail:
Angelica Dahurica Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
In vitro research shows that ashitaba extract inhibits cytochrome P450 (CYP) 1A2.
Read the full Angelica Dahurica Root Extract + Acetaminophen, Caffeine, Isometheptene interactionPueraria Lobata Root ExtractCaffeine, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking kudzu with caffeine might increase levels of caffeine.
Read the full Pueraria Lobata Root Extract + Acetaminophen, Caffeine, Isometheptene interactionCitrus Reticulata Peel ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Citrus Reticulata Peel Extract + Acetaminophen, Caffeine, Isometheptene interactionAtractylodes Lancea Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodes Lancea Rhizome Extract + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Curing Pills — through 5 ingredients. Tap an ingredient for the detail:
Pueraria Lobata Root ExtractHepatotoxic Drugs, Caffeine Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract + Acetaminophen, Caffeine, Pyrilamine interactionPoria Cocos Sclerotium ExtractAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Caffeine, Pyrilamine interactionAngelica Dahurica Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
In vitro research shows that ashitaba extract inhibits cytochrome P450 (CYP) 1A2.
Read the full Angelica Dahurica Root Extract + Acetaminophen, Caffeine, Pyrilamine interactionAtractylodes Lancea Rhizome ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, atractylodes might increase the levels of CYP3A4 substrates.
Read the full Atractylodes Lancea Rhizome Extract + Acetaminophen, Caffeine, Pyrilamine interactionCitrus Reticulata Peel ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Citrus Reticulata Peel Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Curing Pills — through 6 ingredients. Tap an ingredient for the detail:
Coix Lacryma Jobi Seed ExtractDextromethorphan (robitussin Dm, Others) Moderate
Interaction Summary
Animal research suggests that Job's tears might enhance absorption of dextromethorphan in the small intestine.
Read the full Coix Lacryma Jobi Seed Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAngelica Dahurica Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
In vitro research shows that ashitaba extract inhibits cytochrome P450 (CYP) 1A2.
Read the full Angelica Dahurica Root Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionPueraria Lobata Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionPoria Cocos Sclerotium ExtractAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAtractylodes Lancea Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodes Lancea Rhizome Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionCitrus Reticulata Peel ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Citrus Reticulata Peel Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Curing Pills — through 6 ingredients. Tap an ingredient for the detail:
Poria Cocos Sclerotium ExtractAnticholinergic Drugs, Cns Depressants Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionPueraria Lobata Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionMagnolia Officinalis Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Officinalis Bark Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAngelica Dahurica Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
In vitro research shows that ashitaba extract inhibits cytochrome P450 (CYP) 1A2.
Read the full Angelica Dahurica Root Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionCitrus Reticulata Peel ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Citrus Reticulata Peel Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAtractylodes Lancea Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodes Lancea Rhizome Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Curing Pills — through 6 ingredients. Tap an ingredient for the detail:
Angelica Dahurica Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
In vitro research shows that ashitaba extract inhibits cytochrome P450 (CYP) 1A2.
Read the full Angelica Dahurica Root Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionCoix Lacryma Jobi Seed ExtractDextromethorphan (robitussin Dm, Others) Moderate
Interaction Summary
Animal research suggests that Job's tears might enhance absorption of dextromethorphan in the small intestine.
Read the full Coix Lacryma Jobi Seed Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionPoria Cocos Sclerotium ExtractAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionPueraria Lobata Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionCitrus Reticulata Peel ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Citrus Reticulata Peel Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAtractylodes Lancea Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodes Lancea Rhizome Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Curing Pills — through 6 ingredients. Tap an ingredient for the detail:
Pueraria Lobata Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionPoria Cocos Sclerotium ExtractAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionCoix Lacryma Jobi Seed ExtractDextromethorphan (robitussin Dm, Others) Moderate
Interaction Summary
Animal research suggests that Job's tears might enhance absorption of dextromethorphan in the small intestine.
Read the full Coix Lacryma Jobi Seed Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAngelica Dahurica Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
In vitro research shows that ashitaba extract inhibits cytochrome P450 (CYP) 1A2.
Read the full Angelica Dahurica Root Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAtractylodes Lancea Rhizome ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, atractylodes might increase the levels of CYP3A4 substrates.
Read the full Atractylodes Lancea Rhizome Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionCitrus Reticulata Peel ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Citrus Reticulata Peel Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Curing Pills with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Atractylodes lancea Rhizome Extract
Anticoagulant/Antiplatelet Drugs
Theoretically, atractylodes might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Laboratory research suggests that atractylenolides II and III, constituents of atractylodes, reduce platelet activation. So far, this has not been shown in humans.
Aromatase Inhibitors
Theoretically, atractylodes may have an additive effect when used with other aromatase inhibitors.
Laboratory research suggests that atractylodes and its constituents exhibit aromatase inhibitor effects.
Hexobarbital
Theoretically, taking atractylodes may prolong the therapeutic and adverse effects of hexobarbital.
In animals, atractylodes has been shown to prolong the effects of hexobarbital. These effects have not been shown in humans.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
In animals, atractylodes administered at high doses has been shown to induce CYP1A2 activity. This effect has not been shown in humans.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, atractylodes might increase the levels of CYP3A4 substrates.
In animals, atractylodes administered at high doses has been shown to inhibit CYP3A1 activity, which is a homolog to the human CYP3A4 enzyme. This effect has not been shown in humans.
Citrus reticulata Peel Extract
Cytochrome P450 3A4 (Cyp3A4) Substrates
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4). This suggests that tangeretin may stimulate CYP3A4 activity. However, in humans, drinking tangerine juice 200 mL slightly delayed the absorption, but did not affect the metabolism, of midazolam, a CYP3A4 substrate. Theoretically, tangerine juice might increase CYP3A4 activity and decrease levels of drugs metabolized by this enzyme. However, this effect is unlikely.
Some drugs metabolized by CYP3A4 include amitriptyline (Elavil), amiodarone (Cordarone), citalopram (Celexa), felodipine (Plendil), lansoprazole (Prevacid), ondansetron (Zofran), prednisone (Deltasone, Orasone), sertraline (Zoloft), sibutramine (Meridia), and many others.
Midazolam (Versed)
In vitro, tangeretin, a constituent of tangerine, appears to increase the metabolism of midazolam in human liver microsomes by up to 52%. However, in humans, drinking tangerine juice 200 mL slightly delayed the absorption, but did not affect the metabolism, of midazolam. Theoretically, tangerine juice might increase the metabolism and reduce the effects of midazolam. However, this effect is unlikely.
Pueraria lobata root extract
Anticoagulant/Antiplatelet Drugs
Theoretically, kudzu may increase the risk of bleeding if used with antiplatelet or anticoagulant drugs.
Kudzu isoflavones are reported to have antiplatelet activity.
Caffeine
Theoretically, taking kudzu with caffeine might increase levels of caffeine.
In healthy males injected with the kudzu constituent puerarin, caffeine clearance and metabolism is inhibited. This effect has been attributed to inhibition of cytochrome P450 1A2 (CYP1A2) enzyme, which is involved in caffeine metabolism. It is unclear if taking kudzu orally would have this same effect.
Estrogens
Theoretically, kudzu might alter the effects of estrogen therapy.
Some research suggests that kudzu has estrogenic effects. This may enhance or inhibit the effects of estrogen therapy.
Hepatotoxic Drugs
Theoretically, concomitant use might have additive hepatotoxic effects.
There is some concern that kudzu can adversely affect the liver.
Methotrexate (Trexall, Others)
Theoretically, taking kudzu with methotrexate might increase the risk of methotrexate toxicity.
Preclinical research suggests that kudzu extract greatly reduces the elimination and increases the toxicity of methotrexate. Kudzu might inhibit organic anion transporters (OATs) that are responsible for hepatobiliary and renal excretion of anions, similar to the interaction between methotrexate and non-steroidal anti-inflammatory drugs (NSAIDs).
Tamoxifen (Nolvadex)
Theoretically, kudzu might interfere with tamoxifen activity.
Some research suggests that kudzu may have estrogenic effects.
Antidiabetes Drugs
Theoretically, taking kudzu with antidiabetes drugs might increase the risk of hypoglycemia.
Kudzu might lower blood glucose levels and have additive effects in patients treated with antidiabetic agents. The dose of diabetes medications might need to be adjusted.
Poria cocos Sclerotium Extract
Anticholinergic Drugs
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
In animal research, poria mushroom essential oil reduces acetylcholinesterase activity. This interaction has not been shown in humans.
Cholinergic Drugs
Theoretically, poria mushroom might have additive effects when used with cholinergic drugs.
In animal research, poria mushroom essential oil reduces acetylcholinesterase activity. This interaction has not been shown in humans.
Cns Depressants
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Animal research shows that poria mushroom extract has sedative properties. This interaction has not been shown in humans.
Magnolia officinalis Bark Extract
Anticoagulant/Antiplatelet Drugs
Theoretically, magnolia might have additive effects and increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
In vitro research shows that the chemicals magnolol and honokiol, isolated from magnolia bark, inhibit platelet aggregation that is experimentally induced by collagen and arachidonic acid. However, they do not inhibit platelet aggregation that is induced by adenosine diphosphate, platelet-activating factor, or thrombin. This interaction has not been reported in humans.
Cns Depressants
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
In vitro and animal research shows that constituents extracted from magnolia bark, especially honokiol and magnolol, have sedative effects. These effects may be due to the inhibition of catecholamine release and modulation of gamma-aminobutyric acid-A (GABA-A) receptors.
Angelica dahurica Root Extract
Cytochrome P450 1A2 (Cyp1A2) Substrates
In vitro research shows that ashitaba extract inhibits cytochrome P450 (CYP) 1A2. Theoretically, concomitant use of ashitaba with CYP1A2 substrates might decrease the clearance of these substrates and increase the risk for adverse effects. However, this interaction has yet to be reported in humans. Until more is known, use with caution.
Coix lacryma jobi Seed Extract
Antidiabetes Drugs
Preliminary evidence shows that constituents of Job's tears might have hypoglycemic effects. Theoretically, concomitant use with drugs that decrease blood glucose levels might increase the risk of hypoglycemia. Some antidiabetes drugs include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.
Chlorzoxazone (Parafon Forte, Paraflex)
Animal research suggests that Job's tears might enhance absorption of chlorzoxazone in the small intestine. Single dose and short-term oral administration of Job's tears bran ethanolic extract along with oral administration of a five-drug cocktail containing chlorzoxazone increases chlorzoxazone peak plasma concentration and area under the plasma concentration-time curve (AUC) without altering major cytochrome P450 activities in the liver. This effect has not been reported in humans.
Dextromethorphan (Robitussin Dm, Others)
Animal research suggests that Job's tears might enhance absorption of dextromethorphan in the small intestine. Single dose oral administration of Job's tears bran ethanolic extract along with oral administration of a five-drug cocktail containing dextromethorphan increases dextromethorphan area under the plasma concentration-time curve (AUC) without altering major cytochrome P450 activities in the liver. This effect has not been reported in humans.
Diltiazem (Cardizem, Others)
Animal research suggests that Job's tears might enhance absorption of diltiazem in the small intestine. Single dose oral administration of Job's tears bran ethanolic extract along with oral administration of a five-drug cocktail containing diltiazem increases diltiazem peak plasma concentration and area under the plasma concentration-time curve (AUC) without altering major cytochrome P450 activities in the liver. This effect has not been reported in humans.
Theophylline
Animal research suggests that Job's tears might enhance absorption of theophylline in the small intestine. Single dose and short-term oral administration of Job's tears bran ethanolic extract along with oral administration of a five-drug cocktail containing theophylline increases theophylline peak plasma concentration and area under the plasma concentration-time curve (AUC) without altering major cytochrome P450 activities in the liver. This effect has not been reported in humans.
Trichosanthes kirilowii Root Extract
Antidiabetes Drugs
Theoretically, concomitant use of Chinese cucumber with antidiabetic drugs may have additive effects and adverse effects. Monitor blood glucose levels closely, dose adjustment may be needed.
Brand information
Manufacturer and brand details for Curing Pills, from the product label.
Plum Flower
- Name
- Mayway Herbs
- City
- Oakland
- State
- CA
- Web Address
- plumflowerherbs.com
Curing Pills by Plum Flower: Common Questions
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The Full Monographs Behind Curing Pills’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Magnolia
Interacts with 351 drugsMagnolia bark and flower buds have a long history in traditional Chinese and Japanese medicine, often for stress, sleep, and digestion. Modern human research is still limited, so we can't be...
Read the full Magnolia monograph → Herb & supplement monographTangerine
Interacts with 643 drugsTangerine is a sweet citrus fruit that is a good source of vitamin C and other nutrients, and is widely enjoyed as food. While the peel and essential oil are used in traditional medicine and...
Read the full Tangerine monograph → Herb & supplement monographPoria Mushroom
Interacts with 417 drugsPoria mushroom (Fu Ling) is a fungus long used in Traditional Chinese Medicine, mainly as a mild diuretic and digestive and calming aid. Modern scientific evidence in humans is very limited,...
Read the full Poria Mushroom monograph → Herb & supplement monographCostus
Costus (Saussurea costus) is a root used in Ayurvedic, Unani, and traditional Chinese medicine, mostly for digestive and respiratory complaints. High-quality human evidence is very limited,...
Read the full Costus monograph → Herb & supplement monographJob's Tears
Interacts with 128 drugsJob's Tears is a grain-like seed long used as a food and in traditional medicine, especially in East Asia. While it is generally safe as a food and is being studied for possible effects on m...
Read the full Job's Tears monograph → Herb & supplement monographAshitaba
Interacts with 186 drugsAshitaba is a leafy plant from Japan that is eaten as a vegetable and taken as a supplement for general health, antioxidant, and heart benefits. Most of the supporting research comes from la...
Read the full Ashitaba monograph → Herb & supplement monographKudzu
Interacts with 584 drugsKudzu is a fast-growing vine whose root has long been used in traditional Chinese medicine and is now studied mostly for reducing alcohol intake. Early research is promising for cutting back...
Read the full Kudzu monograph → Herb & supplement monographChinese Cucumber
Interacts with 86 drugsChinese cucumber (Trichosanthes kirilowii) is a plant used in traditional Chinese medicine, and a protein from its root called trichosanthin (Compound Q) has been studied as an injectable dr...
Read the full Chinese Cucumber monograph → Herb & supplement monographChrysanthemum
Chrysanthemum flowers are most often used as a soothing tea in traditional Chinese medicine and as a folk remedy for eye irritation, colds, and minor inflammation. Solid human evidence for t...
Read the full Chrysanthemum monograph → Herb & supplement monographJapanese Mint
Japanese mint is a menthol-rich plant used mainly for its essential oil in topical rubs, inhalants, and digestive remedies. There is some support for menthol's soothing and cooling effects,...
Read the full Japanese Mint monograph → Herb & supplement monographAtractylodes
Interacts with 801 drugsAtractylodes is a root used for centuries in traditional Chinese, Japanese, and Thai medicine, mostly for digestive complaints and fatigue, often as part of multi-herb formulas. Modern resea...
Read the full Atractylodes monograph →Sources & How We Checked
Curing Pills's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 84 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Magnolia 9 references
- Kuribara H, Kishi E, Hattori N, et al. The anxiolytic effect of two oriental herbal drugs in Japan attributed to honokiol from magnolia bark. J Pharm Pharmacol 2000;52:1425-9. PubMed
- Tachikawa E, Takahashi M, Kashimoto T. Effects of extract and ingredients isolated from Magnolia obovata thunberg on catecholamine secretion from bovine adrenal chromaffin cells. Biochem Pharmacol 2000;60:433-40. PubMed
- Jung KY, Kim DS, Oh SR, et al. Magnone A and B, novel anti-PAF tetrahydrofuran lignans from the flower buds of Magnolia fargesii. J Nat Prod 1998;61:808-11.
- Garrison R, Chambliss WG. Effect of a proprietary Magnolia and Phellodendron extract on weight management: a pilot, double-blind, placebo-controlled clinical trial. Altern Ther Health Med 2006;12:50-4.
- Teng CM, Chen CC, Ko FN, et al. Two antiplatelet agents from Magnolia officinalis. Thromb Res 1988;50:757-65. PubMed
- Ghys K, De Palma A, Vandevenne A, Werbrouck J, Goossens A. Magnolia officinalis bark extract, a recently identified contact allergen in 'anti-ageing' cosmetics. Contact Dermatitis. 2015 Aug;73(2):130-2.
- Raison-Peyron N, Césaire A, Du-Thanh A, Dereure O. Allergic contact dermatitis caused by Magnolia officinalis bark extract in a facial anti-ageing cream. Contact Dermatitis. 2015 Jun;72(6):416-7.
- Nilausen TD, Johansen JD, Thyssen JP. Allergic contact dermatitis of the face caused by Magnolia officinalis bark extract. Contact Dermatitis. 2016;75(6):385-87.
- Amat-Samaranch V, López-Sánchez C, Tubau C, Puig L, Serra-Baldrich E. Vulvar allergic contact dermatitis caused by Magnolia officinalis bark extract. Contact Dermatitis 2022;87(1):96-97.
Tangerine 3 references
- Yuan, J. M., Wang, X. L., Xiang, Y. B., Gao, Y. T., Ross, R. K., and Yu, M. C. Preserved foods in relation to risk of nasopharyngeal carcinoma in Shanghai, China. Int J Cancer 2000;85(3):358-363. DOI
- Backman, J. T., Maenpaa, J., Belle, D. J., Wrighton, S. A., Kivisto, K. T., and Neuvonen, P. J. Lack of correlation between in vitro and in vivo studies on the effects of tangeretin and tangerine juice on midazolam hydroxylation. Clin Pharmacol Ther 2000; PubMed
- Vilaplana, J. and Romaguera, C. Contact dermatitis from the essential oil of tangerine in fragrance. Contact Dermatitis 2002;46(2):108. PubMed
Poria Mushroom 3 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Kim H, Park I, Park K, Park S, Kim YI, Park BG. The positive effects of Poria cocos extract on quality of sleep in insomnia rat models. Int J Environ Res Public Health 2022;19(11):6629. PubMed
- Lv Q, Di X, Bian B, Li K, Guo J. Neuroprotective effects of Poria cocos (Agaricomycetes) essential oil on Aß1-40-induced learning and memory deficit in rats. Int J Med Mushrooms 2022;24(10):73-82.
Costus 6 references
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
- Marzulli, F. N. and Maibach, H. I. Effects of vehicles and elicitation concentration in contact dermatitis testing. I. Experimental contact sensitization in humans. Contact Dermatitis 1976;2(6):325-329. PubMed
- Mitchell, J. C. Contact hypersensitivity to some perfume materials. Contact Dermatitis 1975;1(4):196-199. PubMed
- Benezra, C. and Epstein, W. L. Molecular recognition patterns of sesquiterpene lactones in costus-sensitive patients. Contact Dermatitis 1986;15(4):223-230. PubMed
- Mitchell, J. C. and Epstein, W. L. Contact hypersensitivity to a perfume material, Costus Absolute. The role of sesquiterpene lactones. Arch.Dermatol 1974;110(6):871-873. DOI
- Cheminat, A., Stampf, J. L., Benezra, C., Farrall, M. J., and Frechet, J. M. Allergic contact dermatitis to costus: removal of haptens with polymers. Acta Derm.Venereol. 1981;61(6):525-529. DOI
Job's Tears 3 references
- Chiang W, Cheng C, Chiang M, Chung KT. Effects of dehulled adlay on the culture count of some microbiota and their metabolism in the gastrointestinal tract of rats. J Agric Food Chem 2000;48:829-32. PubMed
- Yu YM, Chang WC, Liu CS, Tsai CM. Effect of young barley leaf extract and adlay on plasma lipids and LDL oxidation in hyperlipidemic smokers. Biol Pharm Bull 2004;27:802-5. PubMed
- Yao HT, Lin JH, Liu YT, Li ML, Chiang W. Food-Drug Interaction between the Adlay Bran Oil and Drugs in Rats. Nutrients 2019;11(10):2473. PubMed
Ashitaba 2 references
- Kwon D, Yoon S, Carter O, Bailey GS, Dashwood RH. Antioxidant and antigenotoxic activities of Angelica keiskei, Oenanthe javanica and Brassica oleracea in the Salmonella mutagenicity assay and in HCT116 human colon cancer cells. Biofactors. 2006;26(4):231
- Noh HM, Ahn EM, Yun JM, Cho BL, Paek YJ. Angelica keiskei Koidzumi extracts improve some markers of liver function in habitual alcohol drinkers: a randomized double-blind clinical trial. J Med Food. 2015;18(2):166-72.
Kudzu 21 references
- Woo J, Lau E, Ho SC, et al. Comparison of Pueraria lobata with hormone replacement therapy in treating the adverse health consequences of menopause. Menopause 2003;10:352-61. PubMed
- Akita H, Sowa J, Makiura M, et al. Maculopapular drug eruption due to the Japanese herbal medicine Kakkonto (kudzu or arrowroot decoction). Contact Dermatitis 2003;48:348-9. PubMed
- Luo ZR, Zheng B. [Effect of Puerarin on platelet activating factors CD63 and CD62P, plasminogen activator inhibitor and C-reactive protein in patients with unstable angia pectoris]. Zhongguo Zhong Xi Yi Jie He Za Zhi 2001;21:31-3 .
- Lee KT, Sohn IC, Kim DH, et al. Hypoglycemic and hypolipidemic effects of tectorigenin and kaikasaponin III in the streptozotocin-lnduced diabetic rat and their antioxidant activity in vitro. Arch Pharm Res 2000;23:461-6.
- Yu Z, Zhang G, Zhao H. [Effects of Puerariae isoflavone on blood viscosity, thrombosis and platelet function]. Zhong Yao Cai 1997;20:468-9.
- Hsu FL, Liu IM, Kuo DH, et al. Antihyperglycemic effect of puerarin in streptozotocin-induced diabetic rats. J Nat Prod 2003;66:788-92. PubMed
- Chiang HM, Fang SH, Wen KC, et al. Life-threatening interaction between the root extract of Pueraria lobata and methotrexate in rats. Toxicol Appl Pharmacol 2005;209:263-8.
- Zheng, J., Chen, B., Jiang, B., Zeng, L., Tang, Z. R., Fan, L., and Zhou, H. H. The effects of puerarin on CYP2D6 and CYP1A2 activities in vivo. Arch Pharm Res 2010;33(2):243-246. PubMed
- Hsu, H. H., Chang, C. K., Su, H. C., Liu, I. M., and Cheng, J. T. Stimulatory effect of puerarin on alpha1A-adrenoceptor to increase glucose uptake into cultured C2C12 cells of mice. Planta Med 2002;68(11):999-1003.
- Zheng, G., Zhang, X., Zheng, J., Meng, Q., and Zheng, D. [Estrogen-like effects of puerarin and total isoflavones from Pueraria lobata]. Zhong.Yao Cai. 2002;25(8):566-568.
- Qi, B. L. and Qi, B. M. [Effect of the purariae-isofiavones on estrogen level in normal and ovariectomized rats]. Zhongguo Zhong.Yao Za Zhi. 2002;27(11):850-852.
- Akita, H., Sowa, J., Makiura, M., Akamatsu, H., and Matsunaga, K. Maculopapular drug eruption due to the Japanese herbal medicine Kakkonto (kudzu or arrowroot decoction). Contact Dermatitis 2003;48(6):348-349. PubMed
- Manonai, J., Chittacharoen, A., Theppisai, U., and Theppisai, H. Effect of Pueraria mirifica on vaginal health. Menopause. 2007;14(5):919-924. PubMed
- Chandeying, V. and Sangthawan, M. Efficacy comparison of Pueraria mirifica (PM) against conjugated equine estrogen (CEE) with/without medroxyprogesterone acetate (MPA) in the treatment of climacteric symptoms in perimenopausal women: phase III study. J M
- Virojchaiwong, P., Suvithayasiri, V., and Itharat, A. Comparison of Pueraria mirifica 25 and 50 mg for menopausal symptoms. Arch.Gynecol.Obstet. 2011;284(2):411-419. PubMed
- Hou, Q., Ao, X., Li, G., and Zhang, Y. [Puerarin combined with avandia for diabetic nephropathy]. Zhong.Nan.Da.Xue Xue Bao Yi Xue Ban. 2012;37(1):73-77.
- Kim HJ, Kim H, Ahn JH, Suk JH. Liver injury induced by herbal extracts containing mistletoe and kudzu. J Altern Complement Med 2015;21(3):180-5. PubMed
- Santosh N, Mohan K, Royana S, Yamini TB. Hepatotoxicity of tubers of Indian Kudzu (Pueraria tuberosa) in rats. Food Chem Toxicol. 2010 Apr;48(4):1066-71. PubMed
- Teschke R, Zhang L, Long H, Schwarzenboeck A, Schmidt-Taenzer W, Genthner A, Wolff A, Frenzel C, Schulze J, Eickhoff A. Traditional Chinese Medicine and herbal hepatotoxicity: a tabular compilation of reported cases. Ann Hepatol. 2015 Jan-Feb;14(1):7-19. DOI
- Wang D, Qiu L, Wu X, Wei H, Xu F. Evaluation of kudzu root extract-induced hepatotoxicity. J Ethnopharmacol. 2015 Dec 24;176:321-6. PubMed
- Warinsiriruk P, Tantitham C, Cherdshewasart W, Shobeiri SA, Manonai J. Effects of Pueraria mirifica on vaginal artery vascularization in postmenopausal women with genitourinary syndrome of menopause. Maturitas 2022;160:4-10. PubMed
Chinese Cucumber 4 references
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Hikino H, Yoshizawa M, Suzuki Y, et al. Isolation and hypoglycemic activity of trichosans A, B, C, D, and E: glycans of Trichosanthes kirilowii roots. Planta Med 1989;55:349-50.
- Jung YB, Roh KJ, Jung JA, et al. Effect of SKI 306X, a new herbal anti-arthritic agent, in patients with osteoarthritis of the knee: a double-blind placebo controlled study. Am J Chin Med. 2001;29(3-4):485-91. PubMed
Chrysanthemum 25 references
- Kuno Y, Kawabe Y, Sakakibara S. Allergic contact dermatitis associated with photosensitivity, from alantolactone in a chrysanthemum farmer. Contact Dermatitis 1999;40:224-5. PubMed
- deJong NW, Vermeulen AM, van Wijik RG, deGroot H. Occupational allergy caused by flowers. Allergy 1998;53:204-9. PubMed
- Camplimi P, Sertoli A, Fabbri P, Panconesi E. Alantolactone sensitivity in chrysanthemum contact dermatitis. Contact Dermatitis 1978;4:93-102. PubMed
- Bleumink E, Mitchell JC, Geismann TA, Towers GH. Contact hypersensitivity to sesquiterpene lactones in Chrysanthemum dermatitis. Contact Dermatitis 1976;2:81-8.
- Lamminpaa A, Estlander T, Jolanki R, Kanerva L. Occupational allergic contact dermatitis caused by decorative plants. Contact Dermatitis 1996;34:330-5. PubMed
- Hausen BM. The sensitizing capacity of Compositae plants. III. Test results and cross-reactions in Compositae-sensitive patients. Dermatologica 1979;159:1-11. DOI
- Kuno, Y., Kawabe, Y., and Sakakibara, S. Allergic contact dermatitis associated with photosensitivity, from alantolactone in a chrysanthemum farmer. Contact Dermatitis 1999;40(4):224-225. PubMed
- Schulz, K. H., Hausen, B. M., Wallhofer, L., and Schmidt-Loffler, P. Chrysanthemum allergy. Pt. II: Experimental studies on the causative agents. Arch.Dermatol.Forsch. 1975;251(3):235-244.
- Singhal, V. and Reddy, B. S. Common contact sensitizers in Delhi. J Dermatol 2000;27(7):440-445. PubMed
- Kuroume, T., Todokoro, M., Tomidokoro, H., Kanbe, Y., and Matsumura, T. Chrysanthemum pollinosis in Japan. Int.Arch.Allergy Appl.Immunol. 1975;48(6):800-811.
- Groenewoud, G. C., de Jong, N. W., Burdorf, A., de Groot, H., and van Wyk, R. G. Prevalence of occupational allergy to Chrysanthemum pollen in greenhouses in the Netherlands. Allergy 2002;57(9):835-840.
- Jovanovic, M. and Poljacki, M. [Compositae dermatitis]. Med Pregl. 2003;56(1-2):43-49. PubMed
- Hashimoto, Y., Kawada, A., Aragane, Y., and Tezuka, T. Occupational contact dermatitis from chrysanthemum in a mortician. Contact Dermatitis 2003;49(2):106-107. PubMed
- Groenewoud, G. C., de Groot, H., and van Wijk, R. G. Impact of occupational and inhalant allergy on rhinitis-specific quality of life in employees of bell pepper greenhouses in the Netherlands. Ann Allergy Asthma Immunol 2006;96(1):92-97. PubMed
- Sharma, S. C. and Kaur, S. Airborne contact dermatitis from Compositae plants in northern India. Contact Dermatitis 1989;21(1):1-5. PubMed
- Sharma, S. C., Tanwar, R. C., and Kaur, S. Contact dermatitis from chrysanthemums in India. Contact Dermatitis 1989;21(2):69-71. PubMed
- Tanaka, T., Moriwaki, S. I., and Horio, T. Occupational dermatitis with simultaneous immediate and delayed allergy to chrysanthemum. Contact Dermatitis 1987;16(3):152-154. PubMed
- Frain-Bell, W., Hetherington, A., and Johnson, B. E. Contact allergic sensitivity to chrysanthemum and the photosensitivity dermatitis and actinic reticuloid syndrome. Br.J.Dermatol. 1979;101(5):491-501. PubMed
- Diener, C., Schlenvoigt, G., Jager, L., Prater, E., and Schubert, H. Allergens of chrysanthemum pollen. Allergol.Immunopathol.(Madr.) 1986;14(1):49-53.
- Zeller, W., de Gols, M., and Hausen, B. M. The sensitizing capacity of Compositae plants. VI. Guinea pig sensitization experiments with ornamental plants and weeds using different methods. Arch Dermatol.Res 1985;277(1):28-35. PubMed
- Schmidt, R. J. When is a chrysanthemum dermatitis not a chrysanthemum dermatitis? The case for describing florists' chrysanthemums as Dendranthema cultivars. Contact Dermatitis 1985;13(2):115-119.
- Schmidt, R. J. and Kingston, T. Chrysanthemum dermatitis in South Wales; diagnosis by patch testing with feverfew (Tanacetum parthenium) extract. Contact Dermatitis 1985;13(2):120-121.
- Mitchell, J. C., Geissman, T. A., Dupuis, G., and Towers, G. H. Allergic contact dermatitis caused by Artemisia and Chrysanthemum species. The role of sesquiterpene lactones. J.Invest Dermatol. 1971;56(2):98-101. PubMed
- Sugai, T., Takahashi, Y., and Okuno, F. Chrysanthemum dermatitis in Japan. Contact Dermatitis 1980;6(2):155. PubMed
- Wakelin, S. H., Marren, P., Young, E., and Shaw, S. Compositae sensitivity and chronic hand dermatitis in a seven-year-old boy. Br J Dermatol 1997;137(2):289-291. PubMed
Japanese Mint 2 references
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
Atractylodes 6 references
- Liu Y, Jia Z, Dong L, et al. A randomized pilot study of atractylenolide I on gastric cancer cachexia patients. Evid Based Complement Alternat Med 2008;5:337-44. PubMed
- Chen Y, Yang W, Guo L, Wu X, Zhang T, Liu J, Zhang J. Atractylodes lactone compounds inhibit platelet activation. Platelets. 2017 Mar;28(2):194-202. PubMed
- Jiang H, Shi J, Li Y. Screening for compounds with aromatase inhibiting activities from Atractylodes macrocephala Koidz. Molecules. 2011 Apr 14;16(4):3146-51. PubMed
- Koonrungsesomboon N, Na-Bangchang K, Karbwang J. Therapeutic potential and pharmacological activities of Atractylodes lancea (Thunb.) DC. Asian Pac J Trop Med. 2014 Jun;7(6):421-8. PubMed
- Li L, Tang LY, Man GC, Yeung BH, Lau CB, Leung PC, Wang CC. Potential reproductive toxicity of Largehead Atractylodes Rhizome, the most commonly used Chinese medicine for threatened miscarriage. Hum Reprod. 2011 Dec;26(12):3280-8. PubMed
- Muhamad N, Plengsuriyakarn T, Na-Bangchang K. Atractylodes lancea for cholangiocarcinoma: Modulatory effects on CYP1A2 and CYP3A1 and pharmacokinetics in rats and biodistribution in mice. PLoS One 2022;17(11):e0277614. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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