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Dietary supplement

Damiana Ingredients & Drug Interactions

by Hawaii Pharm

Damiana label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Damiana against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Damiana is a dietary supplement by Hawaii Pharm with 1 active ingredient. Its ingredients are commonly taken for low libido / aphrodisiac, anxiety and stress, mood and mild low energy.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Damiana Leaf Extract, Dry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Damiana by Hawaii Pharm

Ask about any prescription or over-the-counter medication and we check it for interactions with Damiana by Hawaii Pharm — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Damiana by Hawaii Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 23, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Hawaii Pharm Damiana contains one active ingredient: damiana leaf extract in dried form. The liquid formula also includes alcohol, water, and glycerin as inactive ingredients that make up the base of the product.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: sexual function and mood support.
  • We looked for evidence on: Erectile dysfunction (ED), Sexual dysfunction, Depression, Anxiety, Stress, Libido.
  • The closest evidence on file: Damiana is rated "Insufficient Reliable Evidence To Rate" for Sexual dysfunction (Natural Medicines).
  • Also on file: Damiana is rated "Insufficient Reliable Evidence To Rate" for Depression, Erectile dysfunction (ED).

The evidence we hold for damiana doesn't establish it as effective for any of the conditions studied — sexual dysfunction, asthma, headache, cognitive function, constipation, and depression all have insufficient reliable evidence to rate. That doesn't mean it doesn't work; it means the data we have isn't strong enough to say one way or the other.

The evidence, ingredient by ingredient Damiana

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Damiana is likely well tolerated in food or tea amounts for most adults, but human safety data are limited overall. At very high doses — 200 grams of extract — it's been associated with serious effects including tetanus-like convulsions and symptoms resembling rabies or strychnine poisoning.

The safety data advises against use during pregnancy and while breastfeeding because there isn't enough information to know it's safe in those situations.

Side effects, ingredient by ingredient Damiana

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Damiana.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check before combining damiana with antidiabetes drugs (the medications you take for blood sugar control) — there's a Moderate risk that it could lower your blood sugar too much. No other medication interactions are documented for the ingredient we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you take antidiabetes drugs, damiana isn't off the table, but it does need a closer look with your doctor or pharmacist beforehand — they can help you weigh the risk of low blood sugar against any benefit you might see. For other uses, the evidence isn't there yet.

Talk it over with your own healthcare provider before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Damiana, straight from the product label.

Brand Hawaii Pharm
Barcode (UPC) 840253617538
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Nov 22, 2023
DSLD ID 301512
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Damiana by Hawaii Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.7 mL
Maximum serving Sizes:
1 mL
Servings per container
120
UPC/BARCODE
840253617538
IngredientAmount% DV
Damiana Leaf Extract, Dry983 mg--

Other ingredients: Alcohol, Water, Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Hawaii Pharm Herbal Extract Highest quality since 2008

Suggested/Recommended/Usage/Directions

Suggested use: Shake well before using. For adults add about 20-30 drops (0.7-1 mL, one full squeeze of the dropper bulb) to some juice or water, up to 4 times a day.

Precautions

Warning: We recommend to seek expert medical advice before taking.

Do not use if you are allergic to any ingredients.

Consult your physician before giving to children under 18, during pregnancy, if nursing or taking medications.

Consult your physician before giving to children under 18, during pregnancy, if nursing or taking medications.

May affect the ability to drive and operate machinery. May have contraindications, can cause side effects and adverse reactions. Do not use if seal is broken or missing.

Keep out of the reach of children!

Storage

Store in a cool dry place.

Seals/Symbols

cGMP Made in compliance with cGMP 21 CFR 111 in an FDA registered and inspected facility.

Organic Alcohol Based USA Made in United States of America

FDA Disclaimer Statement

This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Scan this QR-code to get 15% discount on your next purchase. Limited time deal.

Formula

Turnera diffusa

Organic Alcohol Based

Formulation

Only natural ingredients Purity is laboratory tested and verified

All the raw materials are gluten-free by their nature No artificial colors, flavors, or preservatives

Not tested on animals

Organic Alcohol Based

Made in USA, Hawaii

FDA Statement of Identity

Herbal Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Damiana by Hawaii Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Damiana label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Damiana by Hawaii Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.7 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.

Damiana Leaf Extract, Dry

Interacts with
86 drugs
983 mg per serving

Damiana is a traditional herb most famous as an aphrodisiac and mild mood-lifter, but solid human evidence for any of its uses is very limited. It is...

Damiana Leaf Extract, Dry monograph & interactions

Other (inactive) ingredients: Alcohol, Water, Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Damiana by Hawaii Pharm Drug Interactions

Want to check YOUR meds against Damiana?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Damiana Leaf Extract, Dry 86

Individual Drug Interactions

The ingredients in Damiana interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in Damiana interact with drugs. Each result below shows which ingredient is responsible. Damiana Leaf Extract, Dry

Each ingredient & the kinds of drugs it affects

For each ingredient in Damiana with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Damiana Leaf Extract, Dry1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research shows that taking damiana lowers blood glucose level.

Likelihood Possible Evidence D
Damiana Leaf Extract, Dry full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Damiana, from the product label.

Hawaii Pharm

See all Hawaii Pharm products
Name
Hawaii Pharm LLC
Street Address
510 Sumner St. Ste. 613
City
Honolulu
State
HI
ZipCode
96817
Phone Number
888-854-2924
Web Address
www.hawaiipharm.com
Pharmacist Counseling Corner

Damiana by Hawaii Pharm: Common Questions

Does Damiana by Hawaii Pharm interact with any medications?
Yes. Based on its ingredients, Damiana has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Damiana contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take damiana if I'm pregnant or breastfeeding?
The safety data advises against it. There isn't enough information to know whether damiana is safe during pregnancy or while breastfeeding, so it's best to avoid it in those situations and talk with your doctor or pharmacist for personalized advice.
Does damiana actually work for sexual dysfunction?
The evidence we hold is insufficient to say either way. There's not enough reliable data yet to rate whether it works for sexual dysfunction or the other conditions it's used for — depression, headache, cognitive function, constipation, and asthma.
What are the side effects of damiana?
At normal doses, damiana is likely well tolerated, though human safety data are limited. At very high doses — 200 grams of extract — it's caused serious effects including convulsions and symptoms resembling rabies or strychnine poisoning. Always stick to the dose on the label.
Is this product just damiana, or does it have other active ingredients?
It's one ingredient: damiana leaf extract. The other components — alcohol, water, and glycerin — are inactive ingredients that make up the liquid base.
I take diabetes medication. Is damiana safe for me?
That's a question for your doctor or pharmacist. Damiana may lower blood sugar, so combining it with your diabetes drugs could increase the risk of low blood sugar. They can help you decide whether it's okay for you and keep an eye on your levels if you do take it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Damiana is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Damiana label
Go deeper

The Full Monographs Behind Damiana’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Damiana

Interacts with 86 drugs

Damiana is a traditional herb most famous as an aphrodisiac and mild mood-lifter, but solid human evidence for any of its uses is very limited. It is generally well tolerated in the small am...

Read the full Damiana monograph →
Sources

Sources & How We Checked

Damiana's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Damiana 2 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Alarcon-Aquilar FJ, Roman-Ramos R, Perez-Gutierrez S, et al. Study of the anti-hyperglycemic effect of plants used as antidiabetics. J Ethnopharmacol 1998;61:101-10. PubMed

See these in context on the Damiana monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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