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Dietary supplement

Damiana Leaf Ingredients & Drug Interactions

by Indiana Botanic Gardens

Damiana Leaf label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Damiana Leaf against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Damiana Leaf is a dietary supplement by Indiana Botanic Gardens with 1 active ingredient. Its ingredients are commonly taken for low libido / aphrodisiac, anxiety and stress, mood and mild low energy.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Damiana leaf extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Damiana Leaf by Indiana Botanic Gardens

Ask about any prescription or over-the-counter medication and we check it for interactions with Damiana Leaf by Indiana Botanic Gardens — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Damiana Leaf by Indiana Botanic Gardens

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 23, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: damiana leaf extract. It's prepared as a liquid in vegetable glycerin and purified water.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Damiana product and its label doesn't state a use — see Damiana's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for damiana is limited. We hold insufficient reliable evidence to rate it for sexual dysfunction, asthma, headache, cognitive function, constipation, or depression.

If you're thinking about using it for any of these purposes, the research backing its use isn't established in the data we have.

The evidence, ingredient by ingredient Damiana

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Damiana is likely fine in food or tea amounts for most adults, though human safety data are limited. At very high doses — 200 grams of extract — it has caused serious effects like tetanus-like convulsions and symptoms resembling rabies or strychnine poisoning.

The safety data don't support use during pregnancy or while breastfeeding, so you should avoid it at those times.

Side effects, ingredient by ingredient Damiana

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Damiana.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antidiabetes drugs (like insulin, metformin, or others that lower blood sugar), double-check with your doctor or pharmacist before starting this product — damiana may increase your risk of low blood sugar.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Damiana leaf extract is generally well tolerated in typical amounts, but if you take antidiabetes drugs, you'll want to check this one with your doctor or pharmacist first — it may lower blood sugar further. The evidence for its effectiveness isn't strong enough to rate yet.

Pregnant or breastfeeding? Skip it until you've talked with your healthcare provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Damiana Leaf, straight from the product label.

Brand Indiana Botanic Gardens
Barcode (UPC) 703308200829
Net contents 1 fl. Oz.; 30 mL
Market status On market
Date entered into DSLD Jul 24, 2015
DSLD ID 47414
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Damiana Leaf by Indiana Botanic Gardens, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
2 mL
Servings per container
15
UPC/BARCODE
703308200829
IngredientAmount% DV
Damiana leaf extract2000 mg--

Other ingredients: Vegetable Glycerin, purified Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement take 1-2 mL (approx. 28-56 drops) 3 times a day in a small amount of water.

Shake well.

Precautions

Warning: If you are taking any medications or are pregnant or nursing do not use prior to consulting a physician.

Use only if seal is unbroken

Keep out of reach of children

Storage

Store in a dry, cool place.

Formulation

Alcohol Free Liquid Extract

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

IBG INDIANA BOTANICAL GARDENS(R)

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Damiana Leaf by Indiana Botanic Gardens label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Damiana Leaf label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Damiana Leaf by Indiana Botanic Gardens

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container15 Amounts shown are per serving.

Damiana leaf extract

Interacts with
86 drugs
2000 mg per serving

Damiana is a traditional herb most famous as an aphrodisiac and mild mood-lifter, but solid human evidence for any of its uses is very limited. It is...

Damiana leaf extract monograph & interactions

Other (inactive) ingredients: Vegetable Glycerin, Purified Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Damiana Leaf by Indiana Botanic Gardens Drug Interactions

Want to check YOUR meds against Damiana Leaf?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Damiana leaf extract 86

Individual Drug Interactions

The ingredients in Damiana Leaf interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in Damiana Leaf interact with drugs. Each result below shows which ingredient is responsible. Damiana leaf extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Damiana Leaf with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Damiana leaf extract1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research shows that taking damiana lowers blood glucose level.

Likelihood Possible Evidence D
Damiana leaf extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Damiana Leaf, from the product label.

Indiana Botanic Gardens

See all Indiana Botanic Gardens products
Phone Number
1-800-644-8327
Web Address
www.botanicchoice.com
Pharmacist Counseling Corner

Damiana Leaf by Indiana Botanic Gardens: Common Questions

Does Damiana Leaf by Indiana Botanic Gardens interact with any medications?
Yes. Based on its ingredients, Damiana Leaf has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Damiana Leaf contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take damiana if I'm pregnant or breastfeeding?
No. There isn't enough safety data to know either way, so the advice is to avoid it during pregnancy and while breastfeeding. Talk with your doctor or pharmacist if you have questions about whether it's right for you.
Does damiana work for sexual dysfunction?
We don't have reliable evidence to say whether it does or doesn't. The research backing damiana for sexual dysfunction isn't established enough for us to rate it.
What are the side effects?
At normal doses, damiana is generally well tolerated, though human safety data are limited. At very high doses — 200 grams of extract — it has caused serious effects like convulsions and tremors.
Is this safe if I'm on diabetes medication?
Not without checking first. Damiana can lower blood sugar, and when combined with diabetes drugs, it may cause your blood sugar to drop too far. Talk with your doctor or pharmacist before taking it alongside any antidiabetes medication.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Damiana Leaf is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Damiana Leaf label
Go deeper

The Full Monographs Behind Damiana Leaf’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Damiana

Interacts with 86 drugs

Damiana is a traditional herb most famous as an aphrodisiac and mild mood-lifter, but solid human evidence for any of its uses is very limited. It is generally well tolerated in the small am...

Read the full Damiana monograph →
Sources

Sources & How We Checked

Damiana Leaf's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Damiana 2 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Alarcon-Aquilar FJ, Roman-Ramos R, Perez-Gutierrez S, et al. Study of the anti-hyperglycemic effect of plants used as antidiabetics. J Ethnopharmacol 1998;61:101-10. PubMed

See these in context on the Damiana monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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