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Dietary supplement

Damiana Leaves 450 mg Ingredients & Drug Interactions

by Vitamin World

Damiana Leaves 450 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Damiana Leaves 450 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Damiana Leaves 450 mg is a dietary supplement by Vitamin World with 1 active ingredient. Its ingredients are commonly taken for low libido / aphrodisiac, anxiety and stress, mood and mild low energy.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Damiana. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Damiana Leaves 450 mg by Vitamin World

Ask about any prescription or over-the-counter medication and we check it for interactions with Damiana Leaves 450 mg by Vitamin World — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Damiana Leaves 450 mg by Vitamin World

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 23, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: damiana leaf extract, 450 mg per capsule. Damiana is a plant used traditionally in herbal medicine.

The capsule itself is made from gelatin and a small amount of other inactive ingredients that serve as binders and fillers.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: traditional herbal supplement.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The effectiveness of damiana for its commonly claimed uses—sexual dysfunction, asthma, headache, cognitive function, constipation, and depression—has not been established in reliable scientific studies. The evidence we hold on file rates all of these as insufficient to make a clear recommendation either way.

The evidence, ingredient by ingredient Damiana

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Human safety data for damiana are limited. In normal food or tea amounts it's generally well tolerated by most adults, but we don't have enough long-term study data to know the full safety profile.

At very high doses (200 grams of extract), damiana has caused serious nervous-system symptoms resembling tetanus or poisoning in rare cases—though this is far above the 450 mg dose in this product. Damiana is not recommended during pregnancy or while breastfeeding because there isn't enough safety data to know whether it's safe for your baby.

Talk with your doctor or pharmacist about your individual situation if you're pregnant, planning to become pregnant, or nursing.

Side effects, ingredient by ingredient Damiana

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Damiana.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take any antidiabetes drugs (like insulin, metformin, glipizide, or other blood-sugar-lowering medications), check with your doctor or pharmacist before starting damiana. The supplement can lower blood glucose, and combining it with your medication could drop your blood sugar too far.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Damiana Leaves 450 mg may be worth considering if you're interested in traditional herbal support, but the evidence that it works for any specific condition isn't solid yet. If you take antidiabetes medications, you'll want to check with your doctor or pharmacist first—the blood-sugar-lowering effect could add up with your drugs.

Pregnant or nursing? Skip it unless your doctor says otherwise.

Run your full medication list through the checker on this page before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Damiana Leaves 450 mg, straight from the product label.

Brand Vitamin World
Barcode (UPC) 074312751219
Net contents 100 Rapid Release Capsule(s)
Market status On market
Date entered into DSLD Apr 25, 2013
DSLD ID 20607
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Damiana Leaves 450 mg by Vitamin World, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
UPC/BARCODE
074312751219
IngredientAmount% DV
Damiana450 mg--

Other ingredients: Gelatin, Contains <2% of

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Vitamin World products are subject to critically stringent quality assurance analysis. Our state-of-the-art laboratory, manufacturing and packaging facilities insure the highest quality nutritional supplements money can buy. Your health & safety are our first priority!

NATURAL WHOLE HERB

Vitamin World's Guarantee: We use only the finest quality herbs and spices. Each is screened and finely milled for quick release.

Vitamin World's Natural Whole Herb products utilize ground plant parts to provide the natural components found in nature. Indigenous to Central America, the small leaves of the Damiana plant have been used by the native people for centuries.

Seals/Symbols

QA QUALITY ASSURED

FDA Statement of Identity

Herbal Supplement

Suggested/Recommended/Usage/Directions

DIRECTIONS: For adults, take one (1) to two (2) capsules one to two times daily, preferably with meals. Capsules may be opened and prepared as a tea.

Formulation

Vitamin World's preservative-free gelatin capsules contain pure milled herb powder.

No Artificial Color, Flavor or Sweetener, No Preservatives, No Sugar, No Starch, No Milk, No Lactose, No Soy, No Gluten, No Wheat, No Yeast, No Fish. Sodium Free.

Precautions

WARNING: Not intended for use by pregnant or nursing women. If you are taking any medications, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Not intended for use by persons under the age of 18. Keep out of reach of children.

Do not use if seal under cap is broken or missing.

Storage

Store at room temperature.

General

PROD. #5121 B5121 09C

Brand IP Statement(s)

Get healthy.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Damiana Leaves 450 mg by Vitamin World label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Damiana Leaves 450 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Damiana Leaves 450 mg by Vitamin World

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Damiana

Interacts with
86 drugs
450 mg per serving

Damiana is a traditional herb most famous as an aphrodisiac and mild mood-lifter, but solid human evidence for any of its uses is very limited. It is...

Damiana monograph & interactions

Other (inactive) ingredients: Gelatin, Contains <2% of. These complete the product’s ingredient list but are not active constituents.

Interaction report

Damiana Leaves 450 mg by Vitamin World Drug Interactions

Want to check YOUR meds against Damiana Leaves 450 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Damiana 86

Individual Drug Interactions

The ingredients in Damiana Leaves 450 mg interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in Damiana Leaves 450 mg interact with drugs. Each result below shows which ingredient is responsible. Damiana

Each ingredient & the kinds of drugs it affects

For each ingredient in Damiana Leaves 450 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Damiana1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research shows that taking damiana lowers blood glucose level.

Likelihood Possible Evidence D
Damiana full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Damiana Leaves 450 mg, from the product label.

Vitamin World

See all Vitamin World products
Name
Vitamin World, Inc.
City
Ronkonkoma
State
NY
ZipCode
11779
Pharmacist Counseling Corner

Damiana Leaves 450 mg by Vitamin World: Common Questions

Does Damiana Leaves 450 mg by Vitamin World interact with any medications?
Yes. Based on its ingredients, Damiana Leaves 450 mg has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Damiana Leaves 450 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is damiana safe if I'm pregnant or breastfeeding?
No. There isn't enough safety data to know whether damiana is safe for your baby during pregnancy or while you're nursing. The facts advise against it in both cases. Talk with your doctor or pharmacist if you have questions about what's safe for you right now.
What is damiana supposed to do?
Damiana is traditionally used for sexual dysfunction, asthma, headache, mood, digestion, and focus—but reliable scientific evidence for any of these uses hasn't been established yet. The evidence we hold rates all of them as insufficient to support a clear claim.
What are the side effects?
Human safety data are limited, so we don't have a clear list of common side effects. At very high doses (much more than this 450 mg capsule), damiana extract has caused serious nerve symptoms in rare cases. At normal supplement doses, it's generally well tolerated, but long-term safety data are sparse.
Can I take damiana if I have diabetes?
Not without checking first. Damiana can lower blood sugar, so combining it with antidiabetes medications might drop your blood sugar too low. Talk with your doctor or pharmacist—they can help you decide whether it's safe for you and whether you need to adjust your medication.
How much damiana is in each capsule?
Each capsule contains 450 mg of damiana leaf extract.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Damiana Leaves 450 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Damiana Leaves 450 mg label
Go deeper

The Full Monographs Behind Damiana Leaves 450 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Damiana

Interacts with 86 drugs

Damiana is a traditional herb most famous as an aphrodisiac and mild mood-lifter, but solid human evidence for any of its uses is very limited. It is generally well tolerated in the small am...

Read the full Damiana monograph →
Sources

Sources & How We Checked

Damiana Leaves 450 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Damiana 2 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Alarcon-Aquilar FJ, Roman-Ramos R, Perez-Gutierrez S, et al. Study of the anti-hyperglycemic effect of plants used as antidiabetics. J Ethnopharmacol 1998;61:101-10. PubMed

See these in context on the Damiana monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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