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Dietary supplement

Damiana Leaves 450 mg Ingredients & Drug Interactions

by Botanic Choice

Damiana Leaves 450 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Damiana Leaves 450 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Damiana Leaves 450 mg is a dietary supplement by Botanic Choice with 1 active ingredient. Its ingredients are commonly taken for low libido / aphrodisiac, anxiety and stress, mood and mild low energy.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Damiana. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Damiana Leaves 450 mg by Botanic Choice

Ask about any prescription or over-the-counter medication and we check it for interactions with Damiana Leaves 450 mg by Botanic Choice — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Damiana Leaves 450 mg by Botanic Choice

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 23, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: damiana leaf at 450 mg per capsule. Damiana is a plant traditionally used in herbal medicine, though evidence for its effectiveness in humans is limited.

The capsule itself is made from gelatin and rice flour, which are inactive ingredients that help hold the product together.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Sexual health.
  • We looked for evidence on: Erectile dysfunction (ED), Sexual dysfunction, Libido, Sexual performance.
  • The closest evidence on file: Damiana is rated "Insufficient Reliable Evidence To Rate" for Sexual dysfunction (Natural Medicines).
  • Also on file: Damiana is rated "Insufficient Reliable Evidence To Rate" for Erectile dysfunction (ED).

The evidence for damiana isn't established in our data. Traditionally, it's been used for sexual dysfunction, asthma, headache, mood, cognitive function, and constipation, but we hold insufficient reliable evidence to rate how well it actually works for any of these purposes.

If you're considering it for a specific concern, talk it over with your doctor or pharmacist about what the research actually supports.

The evidence, ingredient by ingredient Damiana

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Damiana is likely well tolerated in the small amounts you'd find in food or tea, though human safety data are limited. The one serious adverse effect on record is that very high doses (200 grams of extract) have caused tetanus-like convulsions and severe neurological symptoms.

At the 450 mg dose in this product, that extreme reaction is unlikely — but it's a reminder that more isn't always better. The safety data don't support use during pregnancy or while breastfeeding, so if you're pregnant, planning pregnancy, or nursing, this isn't the supplement for you.

Side effects, ingredient by ingredient Damiana

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Damiana.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antidiabetes drugs — including insulin, metformin, sulfonylureas, or any other medication that lowers blood sugar — check with your doctor or pharmacist before using this product. Damiana may increase the risk of low blood sugar (hypoglycemia).

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This is a single-ingredient damiana supplement. It may appeal to someone interested in traditional herbal use, but the evidence for its effectiveness isn't established.

The main caution is if you take antidiabetes medications — you'll want to run this by your doctor or pharmacist first, because it could lower your blood sugar further. For pregnancy, breastfeeding, or any health condition, talk it over with your healthcare provider before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 22, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Damiana Leaves 450 mg, straight from the product label.

Brand Botanic Choice
Barcode (UPC) 703308030044
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Dec 22, 2017
DSLD ID 77442
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Damiana Leaves 450 mg by Botanic Choice, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
703308030044
IngredientAmount% DV
Damiana450 mg--

Other ingredients: Gelatin Capsule, Rice Flour

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Herbal Supplement

General Statements

Trusted since 1910 Essentials

Sexual health

Actual pill size

Formulation

Gluten free

Suggested/Recommended/Usage/Directions

Suggested Use: Take 1 capsule 3 times daily, as a dietary supplement, or as directed by a physician.

Best if used by date on bottle.

Precautions

Warning: If you are taking any medications or are pregnant or nursing, do not use prior to consulting a physician.

For your protection, this container has an outer safety seal. (Do not accept if missing or broken.)

Keep out of reach of children.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Storage

Store in a dry, cool place.

Brand IP Statement(s)

IBG Indiana Botanic Gardens

General

C-105501

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Damiana Leaves 450 mg by Botanic Choice label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Damiana Leaves 450 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Damiana Leaves 450 mg by Botanic Choice

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Damiana

Interacts with
86 drugs
450 mg per serving

Damiana is a traditional herb most famous as an aphrodisiac and mild mood-lifter, but solid human evidence for any of its uses is very limited. It is...

Damiana monograph & interactions

Other (inactive) ingredients: Gelatin Capsule, Rice Flour. These complete the product’s ingredient list but are not active constituents.

Interaction report

Damiana Leaves 450 mg by Botanic Choice Drug Interactions

Want to check YOUR meds against Damiana Leaves 450 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Damiana 86

Individual Drug Interactions

The ingredients in Damiana Leaves 450 mg interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in Damiana Leaves 450 mg interact with drugs. Each result below shows which ingredient is responsible. Damiana

Each ingredient & the kinds of drugs it affects

For each ingredient in Damiana Leaves 450 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Damiana1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research shows that taking damiana lowers blood glucose level.

Likelihood Possible Evidence D
Damiana full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Damiana Leaves 450 mg, from the product label.

Botanic Choice

See all Botanic Choice products
Name
Indiana Botanic Gardens, Inc.
Street Address
3401 W. 37th Ave.
City
Hobart
State
IN
ZipCode
46342
Phone Number
1-800-644-8327
Web Address
www.botanicchoice.com
Pharmacist Counseling Corner

Damiana Leaves 450 mg by Botanic Choice: Common Questions

Does Damiana Leaves 450 mg by Botanic Choice interact with any medications?
Yes. Based on its ingredients, Damiana Leaves 450 mg has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Damiana Leaves 450 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I use damiana if I'm pregnant or breastfeeding?
No. The safety data advise against damiana during pregnancy and while breastfeeding because there isn't enough data to know it's safe. Talk with your doctor or pharmacist for personalized guidance.
What is damiana used for?
Traditionally, damiana has been used for sexual dysfunction, asthma, headache, mood, memory, and constipation — but we don't have reliable evidence that it works for any of these. If you're considering it for a specific reason, ask your doctor or pharmacist what research actually supports.
Are there any serious side effects?
At very high doses (200 grams of extract), damiana has caused convulsions and severe neurological symptoms. At the 450 mg dose in this capsule, that extreme reaction isn't expected, but it shows high doses aren't safe.
Is damiana safe for most adults?
In food and tea amounts, damiana is likely well tolerated for most adults, but human safety data are limited. If you have a health condition, take medications, or are pregnant or breastfeeding, check with your doctor or pharmacist first.
What's in the capsule besides damiana?
The capsule contains gelatin and rice flour — these are inactive fillers that help hold the product together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Damiana Leaves 450 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Damiana Leaves 450 mg label
Go deeper

The Full Monographs Behind Damiana Leaves 450 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Damiana

Interacts with 86 drugs

Damiana is a traditional herb most famous as an aphrodisiac and mild mood-lifter, but solid human evidence for any of its uses is very limited. It is generally well tolerated in the small am...

Read the full Damiana monograph →
Sources

Sources & How We Checked

Damiana Leaves 450 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Damiana 2 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Alarcon-Aquilar FJ, Roman-Ramos R, Perez-Gutierrez S, et al. Study of the anti-hyperglycemic effect of plants used as antidiabetics. J Ethnopharmacol 1998;61:101-10. PubMed

See these in context on the Damiana monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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