Interactions on record — worth a quick check against your medications. Based on 5 of 10 ingredients. Check your meds →
Dietary supplement

Dry Cough Ingredients & Drug Interactions

by Pacific BioLogic

Dry Cough label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Dry Cough against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Dry Cough is a dietary supplement by Pacific BioLogic with 10 active ingredients. Its ingredients are commonly taken for sore throat and cough, heartburn and stomach upset, mouth ulcers and digestive complaints.Based on those ingredients, 1,242 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Licorice, Tangerine, Andrographis. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Dry Cough by Pacific BioLogic

Ask about any prescription or over-the-counter medication and we check it for interactions with Dry Cough by Pacific BioLogic — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Dry Cough by Pacific BioLogic

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 23, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 10 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label doesn't break down how much of each component you get.

Dry Cough contains 10 ingredients, including licorice (used traditionally for respiratory comfort), andrographis (studied for throat and digestive support), isatis (a traditional respiratory herb), white mulberry leaf (traditionally used for blood sugar and lung health), and tangerine (a citrus extract). The formula also includes platycodon, zhejiang fritillary, trichosanthis, and peucedanum — four ingredients commonly used in traditional respiratory blends — though detailed human safety and effectiveness data for some of these are limited.

The capsules themselves are made from plant origin material.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Dry cough relief.
  • We looked for evidence on: Common cold, Influenza, Upper respiratory tract infection (URTI), Respiratory tract infections, Acute bronchitis, Tonsillopharyngitis — and 3 related terms.
  • The strongest evidence on file: Andrographis is rated "Possibly Effective" for Tonsillopharyngitis (Natural Medicines).
  • Also on file: Isatis is rated "Insufficient Reliable Evidence To Rate" for Respiratory tract infections.
  • Also on file: Andrographis is rated "Insufficient Reliable Evidence To Rate" for Acute bronchitis, Upper respiratory tract infection (URTI), Influenza.

The evidence base for this product's ingredients is mixed. Licorice shows possibly effective evidence for canker sores and eczema, but has insufficient evidence for asthma and Addison disease.

Andrographis is possibly effective for throat inflammation (tonsillopharyngitis), ulcerative colitis, and osteoarthritis, though insufficient evidence exists for familial Mediterranean fever. White mulberry shows insufficient evidence for diabetes, high cholesterol, osteoporosis, the common cold, and hair loss.

Isatis is possibly effective for psoriasis but has insufficient evidence for respiratory infections, prostate cancer, ulcerative colitis, hepatitis, and aging skin. Tangerine has insufficient evidence for cancer.

For the remaining ingredients — platycodon, zhejiang fritillary, trichosanthis, and peucedanum — effectiveness data is not on file.

The evidence, ingredient by ingredient Licorice Andrographis Isatis White Mulberry Tangerine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Licorice is generally well tolerated in food amounts, but supplements carry risks: high doses or long-term use of the active compound glycyrrhizin can cause serious problems. Orally, the most common side effects are headache, nausea, and vomiting; topical use may cause contact dermatitis.

Avoid licorice in pregnancy due to links to harmful effects, and avoid it while breastfeeding due to insufficient safety data. Andrographis is generally well tolerated short-term, though higher doses (5–10 mg/kg of its active ingredient) and use beyond 14 days increase the risk of nausea, vomiting, diarrhea, headache, fatigue, dizziness, rash, and itching; rare severe allergic reactions including anaphylaxis have been reported.

Avoid andrographis in pregnancy and while breastfeeding. Isatis has limited human safety data and should be avoided in pregnancy and while breastfeeding.

White mulberry leaf is likely safe as food but concentrated supplements may lower blood sugar; avoid medicinal amounts in pregnancy and while breastfeeding. Tangerine fruit is safe as food, though concentrated extracts and essential oils require caution; topical contact with tangerine essential oil may cause dermatitis.

Side effects, ingredient by ingredient Licorice Andrographis Isatis White Mulberry Tangerine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 4 of the 5 matched ingredients can interact with medications — Licorice, Andrographis, White Mulberry, Tangerine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications; heart-rhythm medications.
  • For scale: 1,243 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, have your doctor or pharmacist check if you take digoxin or other heart medications (licorice), blood thinners like warfarin, clopidogrel, or aspirin (licorice and andrographis), blood pressure drugs (andrographis), diabetes medications or metformin (white mulberry and andrographis), immunosuppressants (andrographis), or sedatives like midazolam (licorice and tangerine). These are the medication types with moderate to minor documented interactions; there may be others as well.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Dry Cough's licorice, andrographis, white mulberry, and tangerine ingredients interact with over 1,200 medications, including heart drugs, blood thinners, blood pressure medications, diabetes drugs, and sedatives. If you take any prescription medication, check your exact drugs against the interaction tool on this page before starting.

Both licorice and andrographis should be avoided in pregnancy and while breastfeeding. Talk with your doctor or pharmacist before adding this product to your routine.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 10 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Dry Cough, straight from the product label.

Brand Pacific BioLogic
Barcode (UPC) 065367400900
Net contents 90 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Jan 22, 2021
DSLD ID 241796
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Dry Cough by Pacific BioLogic, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
4 Capsule(s)
Servings per container
22
UPC/BARCODE
065367400900
IngredientAmount% DV
Proprietary Blend0 NP--
Licorice0 NP--
Andrographis0 NP--
Isatis0 NP--
Platycodon0 NP--
Zhejiang Fritillary0 NP--
Trichosanthis0 NP--
Peucedanum0 NP--
White Mulberry0 NP--
Trichosanthis0 NP--
Tangerine0 NP--

Other ingredients: Capsules of plant origin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Dosage: 2-4 capsules 1-4 times daily between meals. Take one of the doses at bedtime and another during the night or as directed by your healthcare practitioner.

Precautions

Caution: If pregnant or nursing, consult your healthcare provider before using this, or any other product. do not take with other cough formulas.

To report a serious adverse event or obtain product information, contact (800) 869-8783

Formulation

Dry Cough is manufactured in an FDA compliant facility in the United States of America from imported and domestic ingredients

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

Powerful tools for gentle healing

525 mg

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

Product of USA

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Dry Cough by Pacific BioLogic label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Dry Cough label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Dry Cough by Pacific BioLogic

These are the 10 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container22 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

0 NP per serving

Other (inactive) ingredients: Capsules of plant origin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Dry Cough by Pacific BioLogic Drug Interactions

Want to check YOUR meds against Dry Cough?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,242Drugs
1,182 Moderate 60 Minor

Ingredients driving the most interactions

Licorice 1,040
Tangerine 643
Andrographis 413
White Mulberry 87

Individual Drug Interactions

The ingredients in Dry Cough interact with 1,242 drugs. Click any drug to see the details.

4 of the 10 ingredients in Dry Cough interact with drugs. Each result below shows which ingredient is responsible. Licorice Tangerine Andrographis White Mulberry

Each ingredient & the kinds of drugs it affects

For each ingredient in Dry Cough with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Licorice18 drug types · 1,040 drugs

Antihypertensive Drugs

Theoretically, licorice might reduce the effects of antihypertensive drugs.
In human research, licorice increases blood pressure in a dose-dependent manner.

Likelihood Possible Evidence B
Cisplatin (Platinol-Aq)

Theoretically, licorice might reduce the effects of cisplatin.
In animal research, licorice diminished the therapeutic efficacy of cisplatin.

Likelihood Possible Evidence D
Corticosteroids

Theoretically, concomitant use of licorice and corticosteroids might increase the side effects of corticosteroids.
Case reports suggest that concomitant use of licorice and oral corticosteroids, such as hydrocortisone, can potentiate the duration of activity and increase blood levels of corticosteroids. Additionally, in one case report, a patient with neurogenic orthostatic hypertension stabilized on fludrocortisone 0.1 mg twice daily developed pseudohyperaldosteronism after recent consumption of large amounts of black licorice.

Likelihood Possible Evidence D
Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, licorice might increase levels of drugs metabolized by CYP2B6.
In vitro research shows that licorice extract and glabridin, a licorice constituent, inhibit CYP2B6 isoenzymes. Licorice extract from the species G. uralensis seems to inhibit CYP2B6 isoenzymes to a greater degree than G. glabra extract in vitro. Theoretically, these species of licorice might increase levels of drugs metabolized by CYP2B6; however, these interactions have not yet been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, licorice might increase levels of drugs metabolized by CYP2C19.
In vitro, licorice extracts from the species G. glabra and G. uralensis inhibit CYP2C19 isoenzymes in vitro. Theoretically, these species of licorice might increase levels of drugs metabolized by CYP2C19; however, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C8 (Cyp2C8) Substrates

Theoretically, licorice might increase levels of drugs metabolized by CYP2C8.
In vitro, licorice extract from the species G. glabra and G. uralensis inhibits CYP2C8 isoenzymes. Theoretically, these species of licorice might increase levels of drugs metabolized by CYP2C8; however, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP2C9.
There is conflicting evidence about the effect of licorice on CYP2C9 enzyme activity. In vitro research shows that extracts from the licorice species G. glabra and G. uralensis moderately inhibit CYP2C9 isoenzymes. However, evidence from an animal model shows that licorice extract from the species G. uralensis can induce hepatic CYP2C9 activity. Until more is known, licorice should be used cautiously in people taking CYP2C9 substrates.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP3A4.
Pharmacokinetic research shows that the licorice constituent glycyrrhizin, taken in a dosage of 150 mg orally twice daily for 14 days, modestly decreases the area under the concentration-time curve of midazolam by about 20%. Midazolam is a substrate of CYP3A4, suggesting that glycyrrhizin modestly induces CYP3A4 activity. Animal research also shows that licorice extract from the species G. uralensis induces CYP3A4 activity. However, licorice extract from G. glabra species appear to inhibit CYP3A4-induced metabolism of testosterone in vitro. It is thought that the G. glabra inhibits CYP3A4 due to its constituent glabridin, which is a moderate CYP3A4 inhibitor in vitro and not present in other licorice species. Until more is known, licorice should be used cautiously in people taking CYP3A4 substrates.

Likelihood Possible Evidence B
Digoxin (Lanoxin)

Theoretically, concomitant use of licorice with digoxin might increase the risk of cardiac toxicity.
Overuse or misuse of licorice with cardiac glycoside therapy might increase the risk of cardiac toxicity due to potassium loss.

Likelihood Possible Evidence D
Diuretic Drugs

Theoretically, concomitant use of licorice with diuretic drugs might increase the risk of hypokalemia.
Overuse of licorice might compound diuretic-induced potassium loss. In one case report, a 72-year-old male with a past medical history of hypertension, type 2 diabetes, hyperlipidemia, arrhythmia, stroke, and hepatic dysfunction was hospitalized with severe hypokalemia and uncontrolled hypertension due to pseudohyperaldosteronism. This was thought to be provoked by concomitant daily consumption of a product containing 225 mg of glycyrrhizin, a constituent of licorice, and hydrochlorothiazide 12.5 mg for 1 month.

Likelihood Possible Evidence D
Estrogens

Theoretically, licorice might increase or decrease the effects of estrogen therapy.
Theoretically, licorice might interfere with estrogen therapy due to estrogenic and anti-estrogenic effects.

Likelihood Possible Evidence D
Loop Diuretics

Theoretically, loop diuretics might increase the mineralocorticoid effects of licorice.
Theoretically, loop diuretics might enhance the mineralocorticoid effects of licorice by inhibiting the enzyme that converts cortisol to cortisone; however, bumetanide (Bumex) does not appear to have this effect.

Likelihood Possible Evidence D
Midazolam (Versed)

Theoretically, licorice might decrease levels of midazolam.
In humans, the licorice constituent glycyrrhizin appears to moderately induce the metabolism of midazolam. This is likely due to induction of cytochrome P450 3A4 by licorice. Until more is known, licorice should be used cautiously in people taking midazolam.

Likelihood Possible Evidence B
P-Glycoprotein Substrates

Theoretically, licorice might decrease the absorption of P-glycoprotein substrates.
In vitro research shows that licorice can increase P-glycoprotein activity.

Likelihood Possible Evidence D
Paclitaxel (Abraxane, Onxol)

Theoretically, licorice might decrease plasma levels and clinical effects of paclitaxel.
Multiple doses of licorice taken concomitantly with paclitaxel might reduce the effectiveness of paclitaxel. Animal research shows that licorice 3 grams/kg given orally for 14 days before intravenous administration of paclitaxel decreases the exposure to paclitaxel and increases its clearance. Theoretically, this occurs because licorice induces cytochrome P450 3A4 enzymes, which metabolize paclitaxel. Notably, a single dose of licorice did not affect exposure or clearance of paclitaxel.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, licorice might decrease plasma levels and clinical effects of warfarin.
Licorice seems to increase metabolism and decrease levels of warfarin in animal models. This is likely due to induction of cytochrome P450 2C9 (CYP2C9) metabolism by licorice. Advise patients taking warfarin to avoid taking licorice.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that licorice induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Methotrexate (Trexall, Others)

Theoretically, licorice might increase levels of methotrexate.
Animal research suggests that intravenous administration of glycyrrhizin, a licorice constituent, and high-dose methotrexate may delay methotrexate excretion and increase systemic exposure, leading to transient elevations in liver enzymes and total bilirubin. This interaction has not yet been reported in humans.

Likelihood Unlikely Evidence D
Licorice full monograph & interactions

Tangerine2 drug types · 643 drugs

Cytochrome P450 3A4 (Cyp3A4) Substrates

In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4). This suggests that tangeretin may stimulate CYP3A4 activity. However, in humans, drinking tangerine juice 200 mL slightly delayed the absorption, but did not affect the metabolism, of midazolam, a CYP3A4 substrate. Theoretically, tangerine juice might increase CYP3A4 activity and decrease levels of drugs metabolized by this enzyme. However, this effect is unlikely.
Some drugs metabolized by CYP3A4 include amitriptyline (Elavil), amiodarone (Cordarone), citalopram (Celexa), felodipine (Plendil), lansoprazole (Prevacid), ondansetron (Zofran), prednisone (Deltasone, Orasone), sertraline (Zoloft), sibutramine (Meridia), and many others.

Likelihood Unlikely Evidence B
Midazolam (Versed)

In vitro, tangeretin, a constituent of tangerine, appears to increase the metabolism of midazolam in human liver microsomes by up to 52%. However, in humans, drinking tangerine juice 200 mL slightly delayed the absorption, but did not affect the metabolism, of midazolam. Theoretically, tangerine juice might increase the metabolism and reduce the effects of midazolam. However, this effect is unlikely.

Likelihood Unlikely Evidence B
Tangerine full monograph & interactions

Andrographis6 drug types · 413 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, andrographis might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Animal and laboratory studies suggest that andrographis has antiplatelet effects.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, andrographis might increase the risk of hypotension when used with antihypertensive drugs.
Animal research suggests that andrographis has hypotensive effects.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.
Laboratory research suggests that andrographolide has immunostimulant activity.

Likelihood Possible Evidence D
Celecoxib (Celebrex)

Theoretically, andrographis extract might increase the maximum concentration and time to peak concentration of celecoxib. The clinical significance of these changes is unclear.
Animal research suggests that andrographis extract taken orally increases the maximum concentration and time to peak concentration of celecoxib but does not appear to impact the area under the curve.

Likelihood Possible Evidence D
Etoricoxib (Arcoxia)

Theoretically, andrographis might decrease the absorption of etoricoxib, although the clinical significance is unclear.
Animal research shows that andrographis extract, or the constituent andrographolide, taken orally with etoricoxib decreases the bioavailability of etoricoxib. However, this reduced bioavailability is not correlated with a reduction in the anti-inflammatory effects of etoricoxib in arthritic mice models. The clinical significance of this interaction is unclear.

Likelihood Possible Evidence D
Glipizide (Glucotrol)

Theoretically, andrographis extract might increase the maximum concentration and area under the curve of glipizide; however, opposite effects are seen with the constituent, andrographolide. The clinical significance of this interaction is unclear.
Animal research suggests that andrographis extract taken orally with glipizide in diabetes-induced rats increases the maximum concentration and area under the curve of glipizide. However, the opposite effect is seen with the constituent, andrographolide, in which the maximum concentration and area under the curve are decreased when taken with glipizide.

Likelihood Possible Evidence D
Andrographis full monograph & interactions

White Mulberry2 drug types · 87 drugs

Antidiabetes Drugs

Theoretically, white mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Clinical research shows that white mulberry leaf can lower blood glucose levels. Advise patients to monitor glucose levels closely.

Likelihood Possible Evidence D
Organic Cation Transporter 2 (Oct2) Substrates

Theoretically, white mulberry leaf might slow the elimination and increase the adverse effects of drugs which are OCT2 substrates.
Animal research shows that coadministration of white mulberry leaf extract with metformin, an OCT2 substrate, slows the renal elimination of metformin via inhibition of OCT2 activity. OCT2 is expressed in the kidneys and is responsible for transporting cationic drugs into tubular epithelial cells in order to be excreted in the urine.

Likelihood Possible Evidence D
White Mulberry full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Dry Cough, from the product label.

Pacific BioLogic

See all Pacific BioLogic products
Name
Pacific BioLogic Co.
City
Concord
State
CA
ZipCode
94521
Phone Number
800 869-8783
Web Address
www.pacificbiologic.com
Pharmacist Counseling Corner

Dry Cough by Pacific BioLogic: Common Questions

Does Dry Cough by Pacific BioLogic interact with any medications?
Yes. Based on its ingredients, Dry Cough has a known interaction with 1,242 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Dry Cough contains 10 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
Licorice and andrographis should both be avoided in pregnancy due to safety concerns. Isatis and white mulberry also lack enough safety data in pregnancy, so medicinal amounts should not be used. For breastfeeding, there isn't enough reliable safety information for licorice, andrographis, isatis, or white mulberry supplements. Talk with your doctor or pharmacist about whether this product is right for you.
What are the most common side effects?
From licorice, expect headache, nausea, or vomiting with oral use, or contact dermatitis if applied to skin. Andrographis may cause abdominal discomfort, altered taste, diarrhea, dizziness, fatigue, headache, nausea, vomiting, rash, or itching — especially at higher doses. White mulberry can cause bloating, flatulence, loose stools, or constipation, though these often improve over time.
Is this supposed to help with colds?
The product name suggests dry cough relief, and several ingredients — licorice, andrographis, isatis, platycodon, zhejiang fritillary, and trichosanthis — are used traditionally for respiratory symptoms. However, the evidence showing this blend actually works for colds or cough is not on file in our data.
What is licorice in this for?
Licorice is included for its traditional use in respiratory support and throat comfort. It has possibly effective evidence for canker sores and eczema, though the evidence for cough or asthma is insufficient.
Are there any fillers or other junk in the capsules?
The capsules themselves are made from plant origin material. The formula lists 10 active ingredients and no other inactive ingredients beyond the capsule material, so there are no added fillers listed.
How long can I safely take this?
Licorice is fine in short-term use at food levels, but long-term or high-dose use carries serious risks. Andrographis safety beyond 14 days or at high doses is less established. For the other ingredients, long-term safety data are limited or not on file, so discuss the right duration with your doctor or pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Dry Cough label
Go deeper

The Full Monographs Behind Dry Cough’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Licorice

Interacts with 1,040 drugs

Licorice root is a traditional remedy used for sore throats, coughs, and digestive complaints, but solid human evidence is limited for most uses. Regular licorice contains glycyrrhizin, whic...

Read the full Licorice monograph → Herb & supplement monograph

Andrographis

Interacts with 413 drugs

Andrographis is a bitter Asian herb traditionally used for colds, flu, and infections, and some studies suggest it may ease cold symptoms and shorten how long they last. The evidence is limi...

Read the full Andrographis monograph → Herb & supplement monograph

Isatis

Isatis is a plant long used in traditional Chinese medicine, mainly for sore throats, fevers, and colds. Modern evidence in people is very limited, so its benefits are not well proven. Talk...

Read the full Isatis monograph → Herb & supplement monograph

White Mulberry

Interacts with 87 drugs

White mulberry leaf is most studied for helping blunt the rise in blood sugar after meals, but the human evidence is limited and not strong. It is generally well tolerated as a food and tea,...

Read the full White Mulberry monograph → Herb & supplement monograph

Tangerine

Interacts with 643 drugs

Tangerine is a sweet citrus fruit that is a good source of vitamin C and other nutrients, and is widely enjoyed as food. While the peel and essential oil are used in traditional medicine and...

Read the full Tangerine monograph →
Sources

Sources & How We Checked

Dry Cough's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 130 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Licorice 92 references
  1. Farese RV Jr, Biglieri EG, Shackleton CH, et al. Licorice-induced hypermineralocorticoidism. N Engl J Med 1991;325:1223-7. PubMed
  2. Sigurjonsdottir HA, Ragnarsson J, Franzson L, Sigurdsson G. Is blood pressure commonly raised by moderate consumption of liquorice? J Hum Hypertens 1995;9:345-8.
  3. Armanini D, Lewicka S, Pratesi C, et al. Further studies on the mechanism of the mineralocorticoid action of licorice in humans. J Endocrinol Invest 1996;19:624-9. PubMed
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Andrographis 26 references
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Isatis 3 references
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White Mulberry 6 references
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Tangerine 3 references
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Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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