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Dietary supplement

DualBio Ingredients & Drug Interactions

by Cellucor

DualBio label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking DualBio against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

DualBio is a dietary supplement by Cellucor with 2 active ingredients. Its ingredients are commonly taken for digestive and gut health, prebiotic to support good bacteria, constipation relief.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lactobacillus acidophilus La-14. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against DualBio by Cellucor

Ask about any prescription or over-the-counter medication and we check it for interactions with DualBio by Cellucor — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of DualBio by Cellucor

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 23, 2026

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 1 of its 2 active ingredients.

DualBio contains two active ingredients. Lactobacillus acidophilus La-14 is a live probiotic — a beneficial bacterium meant to support your gut health.

Fructooligosaccharide is a type of prebiotic fiber that may help feed the good bacteria already in your system. The capsule itself is vegetarian, and the product includes inactive ingredients like glycerin, microcrystalline cellulose, magnesium stearate, and silicon dioxide as binders and fillers.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Moderate

Some clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Antibiotic-associated diarrhea — rated "Possibly Effective" (Lactobacillus Acidophilus) (Natural Medicines).
  • On file: Bacterial vaginosis — rated "Possibly Effective" (Lactobacillus Acidophilus) (Natural Medicines).
  • On file: Helicobacter pylori — rated "Possibly Effective" (Lactobacillus Acidophilus) (Natural Medicines).
  • On file: Irritable bowel syndrome (IBS) — rated "Possibly Effective" (Lactobacillus Acidophilus) (Natural Medicines).

Evidence for both ingredients is still developing. Lactobacillus acidophilus is possibly effective for irritable bowel syndrome (IBS), antibiotic-associated diarrhea, Helicobacter pylori infection, and bacterial vaginosis, but the strength of that evidence varies.

For fructooligosaccharide, we don't yet have enough reliable data to rate whether it helps with osteoporosis, constipation, diabetes, travelers' diarrhea, or high cholesterol. If you're taking this for a specific condition, talk it over with your doctor to see if the evidence supports it for your situation.

The evidence, ingredient by ingredient Fructo-oligosaccharides (fos) Lactobacillus Acidophilus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactobacillus acidophilus is generally well tolerated in healthy adults and children. Fructooligosaccharide is generally well tolerated at food amounts but can cause gas, bloating, flatulence, and abdominal pain — especially at higher doses.

The good news from research is that doses under 10 grams daily of FOS don't seem to increase these symptoms more than placebo in clinical trials, though some people do notice them at first. Since supplement-level doses of FOS haven't been heavily studied long-term, check with your doctor before starting.

With L. acidophilus, live organisms do carry a small theoretical risk of infection in certain immunocompromised patients, though this is uncommon — ask your healthcare provider if you have any concerns about your immune status.

Side effects, ingredient by ingredient Fructo-oligosaccharides (fos) Lactobacillus Acidophilus

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Lactobacillus Acidophilus.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antibiotics, check the timing with your pharmacist — you'll want to separate when you take them from when you take DualBio, since antibiotics can reduce how well the probiotic works. No other medication interactions are documented in our data for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glancePartially disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

DualBio could be worth considering if you're looking to support digestive health, especially if you have IBS or are dealing with antibiotic-associated diarrhea. If you take antibiotics, space them apart from this product and check with your pharmacist on timing.

A small number of people notice gas or bloating when they first start, and the long-term safety data on this combination in supplement form is limited. Talk it over with your doctor or pharmacist before you start, especially if you have any immune concerns.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about DualBio, straight from the product label.

Brand Cellucor
Barcode (UPC) 842595100259
Net contents 56 Capsule(s)
Market status On market
Date entered into DSLD Feb 23, 2018
DSLD ID 82972
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for DualBio by Cellucor, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
28
UPC/BARCODE
842595100259
IngredientAmount% DV
Fructooligosaccharide130 mg--
Lactobacillus acidophilus La-140 NP--

Other ingredients: Glycerin, Vegetarian outer capsule, Microcrystalline Cellulose, Vegetarian inner capsule, Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Take one serving (2 capsules) once daily.

General Statements

Made in the U.S.A. using U.S. and imported ingredients and components.

Probiotics are beneficial microorganisms commonly known for their ability to support digestive health. They work by supporting the proper balance of good bacteria to balance your body's flora - helpful in maintaining healthy bacterial harmony for digestive health. However, probiotic supplements alone can be limited.

Prebiotics act as energy sources for probiotics, helping them to multiply and spread. This patented delivery system allows for the release of prebiotic fiber along with probiotic organisms. Once in the digestive tract, the probiotics utilize the prebiotics to further enhance their benefit.

2-in-1 probiotic & prebiotic solution 10 billion active cultures Patented capsule-in-capsule delivery system 4 week supply

Precautions

Warning: This product is only intended to be consumed by healthy adults, 18 years of age or older.

Before using this product, consult with a licensed, qualified, health care professional, including but not limited to; if you are pregnant or nursing, if you are taking any prescription drug or over-the-counter medication, or have any existing medical condition.

Discontinue use 2 weeks prior to surgery. Immediately discontinue use and contact a medical doctor if you experience any adverse reaction to this product. Do not use if safety seal is broken or missing.

Keep out of reach of children.

Storage

Store in a cool dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Brand IP Statement(s)

Cellucor, DualBio and the logo are trademarks of and distributed by: Nutrabolt

That's why DualBio provides a potent 2-in-1 combination of 10 billion live active probiotic fiber in a patented capsule-in-capsule delivery system.

General

104293

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

DualBio by Cellucor label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

DualBio label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in DualBio by Cellucor

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container28 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Fructooligosaccharide

No known
interactions
130 mg per serving

Fructo-oligosaccharides (FOS) are a type of soluble fiber that acts as a prebiotic, meaning they feed the helpful bacteria in your gut. They are gener...

Fructooligosaccharide monograph & interactions

Lactobacillus acidophilus La-14

Interacts with
182 drugs
0 NP per serving

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy p...

Lactobacillus acidophilus La-14 monograph & interactions

Other (inactive) ingredients: Glycerin, Vegetarian outer capsule, Microcrystalline Cellulose, Vegetarian inner capsule, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

DualBio by Cellucor Drug Interactions

Want to check YOUR meds against DualBio?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Lactobacillus acidophilus La-14 182

Individual Drug Interactions

The ingredients in DualBio interact with 182 drugs. Click any drug to see the details.

1 of the 2 ingredients in DualBio interact with drugs. Each result below shows which ingredient is responsible. Lactobacillus acidophilus La-14

Each ingredient & the kinds of drugs it affects

For each ingredient in DualBio with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Lactobacillus acidophilus La-141 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D
Lactobacillus acidophilus La-14 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for DualBio, from the product label.

Cellucor

See all Cellucor products
Name
Nutrabolt
Street Address
3891 S. Traditions Dr.
City
Bryan
State
TX
ZipCode
77807
Phone Number
1.866.927.9686
Web Address
www.cellucor.com
Pharmacist Counseling Corner

DualBio by Cellucor: Common Questions

Does DualBio by Cellucor interact with any medications?
Yes. Based on its ingredients, DualBio has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
DualBio contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will DualBio help my IBS?
Lactobacillus acidophilus is possibly effective for IBS, but the evidence isn't definitive yet. Whether it'll help you specifically is something to discuss with your doctor — they know your situation best.
What if I'm on antibiotics right now?
Don't take DualBio at the same time as your antibiotic — the antibiotic will kill off the live probiotic bacteria. Ask your pharmacist how long to wait between doses; spacing them a few hours apart is typical, but it depends on your specific antibiotic.
Can I take this if I'm pregnant?
Lactobacillus acidophilus is rated possibly safe in pregnancy, but we don't have enough data on fructooligosaccharide for pregnancy to say one way or the other. Talk with your doctor or midwife before starting — they can give you personalized advice.
Will I get gas and bloating?
Fructooligosaccharide can cause gas, bloating, and abdominal pain, especially when you first start or at higher doses. Research shows that at under 10 grams a day, these symptoms don't happen more than with placebo in studies, but some people do notice them anyway.
Is this safe for kids?
Lactobacillus acidophilus is generally well tolerated in healthy children, but we don't have safety data for fructooligosaccharide in kids at supplement doses. Check with your pediatrician before giving it to your child.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if DualBio is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

DualBio label
Go deeper

The Full Monographs Behind DualBio’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Fructo-oligosaccharides (fos)

Fructo-oligosaccharides (FOS) are a type of soluble fiber that acts as a prebiotic, meaning they feed the helpful bacteria in your gut. They are generally considered safe for most people in...

Read the full Fructo-oligosaccharides (fos) monograph → Herb & supplement monograph

Lactobacillus Acidophilus

Interacts with 182 drugs

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...

Read the full Lactobacillus Acidophilus monograph →
Sources

Sources & How We Checked

DualBio's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 21 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Fructo-oligosaccharides (fos) 6 references
  1. Briet F, et al. Symptomatic response to varying levels of fructo-oligosaccharides consumed occasionally or regularly. Eur J Clin Nutr 1995;49:501-7.
  2. Bouhnik Y, Vahedi K, Achour L, et al. Short-chain fructo-oligosaccharide administration dose-dependently increases fecal bifidobacteria in healthy humans. J Nutr 1999;129:113-6. PubMed
  3. Cummings JH, Macfarlane GT, Englyst HN. Prebiotic digestion and fermentation. Am J Clin Nutr 2001;73:415S-420S. PubMed
  4. Souza DDS, Tahan S, Weber TK, Araujo-Filho HB, de Morais MB. Randomized, double-blind, placebo-controlled parallel clinical trial assessing the effect of fructooligosaccharides in infants with constipation. Nutrients. 2018;10(11). pii: E1602. PubMed
  5. Andermann TM, Fouladi F, Tamburini FB, et al. A Fructo-Oligosaccharide Prebiotic Is Well Tolerated in Adults Undergoing Allogeneic Hematopoietic Stem Cell Transplantation: A Phase I Dose-Escalation Trial. Transplant Cell Ther 2021;27(11):932. PubMed
  6. Dou Y, Yu X, Luo Y, Chen B, Ma D, Zhu J. Effect of Fructooligosaccharides Supplementation on the Gut Microbiota in Human: A Systematic Review and Meta-Analysis. Nutrients 2022;14(16):3298. PubMed

See these in context on the Fructo-oligosaccharides (fos) monograph →

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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