Elderberry Ingredients & Drug Interactions
by GNC Herbal Plus Standardized
What is this page for?
First and foremost: checking Elderberry against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Elderberry is a dietary supplement by GNC Herbal Plus Standardized with 2 active ingredients. Its ingredients are commonly taken for colds, flu (influenza), other respiratory infections.Based on those ingredients, 121 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Elderberry Fruit Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Elderberry by GNC Herbal Plus Standardized
Ask about any prescription or over-the-counter medication and we check it for interactions with Elderberry by GNC Herbal Plus Standardized — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Elderberry by GNC Herbal Plus Standardized
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Every active ingredient lists its own amount on the label.
Why this rating?
- The label discloses an exact amount for 2 of its 2 active ingredients.
- No proprietary blends here — you can verify the dose of every single component.
The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.
Why this rating?
- 1 of the 1 matched ingredient can interact with medications — Elderberry.
- The most serious interaction on file is rated Moderate.
- Some involve high-stakes drug classes: immunosuppressants / transplant drugs.
- For scale: 121 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
- Pregnancy & breastfeeding safety ratings cover 1 of 1.
- General safety write-ups exist for 1 of 1.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 26, 2011.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Elderberry, straight from the product label.
| Brand | GNC Herbal Plus Standardized |
|---|---|
| Barcode (UPC) | 048107070038 |
| Net contents | 100 Vegetarian Capsules |
| Market status | On market |
| Date entered into DSLD | Oct 26, 2011 |
| DSLD ID | 702 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegetarian, Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Elderberry by GNC Herbal Plus Standardized, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Elderberry Fruit Powder | 250 mg | -- |
| Elderberry Fruit Extract | 300 mg | -- |
Other ingredients: Vegetable Cellulose Capsule, Dicalcium Phosphate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement
* This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
FDA Statement of Identity
HERBAL SUPPLEMENT
Formulation
No Sugar, No Artficial Colors, No Artifical Flavors, Sodium Free, No Wheat, No Gluten, No Soy, No Dairy, Yeast Free.
Precautions
KEEP OUT OF REACH OF CHILDREN
WARNING: Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition. Discontinue use two weeks prior to surgery.
Storage
Store in a cool, dry place.
General Statements
550 mg 15% Polyphenols
Made in the USA
Seasonal Antioxidant Defense*
Visit us at www.gnc.com
General
CODE 194912 DGG
Suggested/Recommended/Usage/Directions
Directions: As a dietary supplement, take one capsule two times daily.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Elderberry by GNC Herbal Plus Standardized label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Elderberry by GNC Herbal Plus Standardized
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Elderberry Fruit Powder
Interacts with121 drugs
Elderberry is a popular herbal supplement, mainly taken to help with colds and flu. Some small studies suggest it may modestly shorten cold or flu sym...
Elderberry Fruit Powder monograph & interactionsElderberry Fruit Extract
Interacts with121 drugs
Elderberry is a popular herbal supplement, mainly taken to help with colds and flu. Some small studies suggest it may modestly shorten cold or flu sym...
Elderberry Fruit Extract monograph & interactionsOther (inactive) ingredients: Vegetable Cellulose Capsule, Dicalcium Phosphate. These complete the product’s ingredient list but are not active constituents.
Elderberry by GNC Herbal Plus Standardized Drug Interactions
Elderberry contains 2 ingredients, and 1 of them has known drug interactions. Altogether it interacts with 121 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Elderberry?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Elderberry interact with 121 drugs. Click any drug to see the details.
1 of the 2 ingredients in Elderberry interact with drugs. Each result below shows which ingredient is responsible. Elderberry Fruit Powder
CyclophosphamideCytoxan, Neosar
How Cyclophosphamide interacts with Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract + Cyclophosphamide interactionCyclosporineCequa, Ciclosporine, Gengraf, Neoral, Sandimmune, Verkazia +1 more
How Cyclosporine interacts with Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract + Cyclosporine interactionDaclizumabZenapax, Zinbryta
How Daclizumab interacts with Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract + Daclizumab interactionDeflazacortEmflaza
How Deflazacort interacts with Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract + Deflazacort interactionDenosumabProlia, XGEVA
How Denosumab interacts with Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract + Denosumab interactionDeucravacitinibSotyktu
How Deucravacitinib interacts with Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract + Deucravacitinib interactionDexamethasoneDecadron, Dexone, Dextenza, Dexycu, Hemady, Hexadrol +1 more
How Dexamethasone interacts with Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract + Dexamethasone interactionDiroximel FumarateVumerity
How Diroximel Fumarate interacts with Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract + Diroximel Fumarate interactionDurvalumabImfinzi
How Durvalumab interacts with Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract + Durvalumab interactionEculizumabSoliris
How Eculizumab interacts with Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract + Eculizumab interactionEfalizumabRaptiva
How Efalizumab interacts with Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract + Efalizumab interactionEfgartigimod Alfa-fcabVyvgart
How Efgartigimod Alfa-fcab interacts with Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract + Efgartigimod Alfa-fcab interactionElranatamabElrexfio
How Elranatamab interacts with Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract + Elranatamab interactionEmapalumab-lzsgGamifant
How Emapalumab-lzsg interacts with Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract + Emapalumab-lzsg interactionEpcoritamab-byspEpkinly
How Epcoritamab-bysp interacts with Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract + Epcoritamab-bysp interactionEtanercept-szzsErelzi
How Etanercept-szzs interacts with Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract + Etanercept-szzs interactionEtanercept-ykroEticovo
How Etanercept-ykro interacts with Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract + Etanercept-ykro interactionEtrasimodVelsipity
How Etrasimod interacts with Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract + Etrasimod interactionFingolimodGilenya, Tascenso ODT
How Fingolimod interacts with Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract + Fingolimod interactionFludrocortisoneFlorinef Acetate
How Fludrocortisone interacts with Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract + Fludrocortisone interactionFluorouracil (iv)Fluorouracil
How Fluorouracil (iv) interacts with Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract + Fluorouracil (iv) interactionFlupenthixolFluanxol
How Flupenthixol interacts with Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract + Flupenthixol interactionFostamatinibTavalisse
How Fostamatinib interacts with Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract + Fostamatinib interactionGlatiramer AcetateCopaxone
How Glatiramer Acetate interacts with Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract + Glatiramer Acetate interactionGlofitamab-gxbmColumvi
How Glofitamab-gxbm interacts with Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract + Glofitamab-gxbm interactionGolimumabSimponi Aria
How Golimumab interacts with Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract + Golimumab interactionGuselkumabTremfya
How Guselkumab interacts with Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract + Guselkumab interactionHyaluronidase, RituximabRituxan Hycela
How Hyaluronidase, Rituximab interacts with Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract + Hyaluronidase, Rituximab interactionHydrocortisoneAlkindi Sprinkle, Alphaderm, Calmurid HC, Carmol HC cream, Cortef, Dioderm +8 more
How Hydrocortisone interacts with Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract + Hydrocortisone interactionInebilizumab-cdonUplizna
How Inebilizumab-cdon interacts with Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract + Inebilizumab-cdon interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Elderberry with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Elderberry Fruit Powder
Immunosuppressants
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Elderberry has immunostimulant activity, increasing the production of cytokines, including interleukin and tumor necrosis factor.
Pazopanib (Votrient)
Theoretically, elderberry might interact with pazopanib, potentially increasing the risk of adverse effects.
Brand information
Manufacturer and brand details for Elderberry, from the product label.
GNC Herbal Plus Standardized
See all GNC Herbal Plus Standardized products- Phone Number
- 1-888-462-2548
Elderberry by GNC Herbal Plus Standardized: Common Questions
Does Elderberry by GNC Herbal Plus Standardized interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Elderberry is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Elderberry’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Elderberry's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 6 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Elderberry 6 references
- Barak V, Halperin T, Kalickman I. The effect of Sambucol, a black elderberry-based, natural product, on the production of human cytokines: I. Inflammatory cytokines. Eur Cytokine Netw 2001;12:290-6..
- Elderberry (Sambucus species). The Poison Plant Patch, Novia Scotia Museum, 2007. Available at: http://museum.gov.ns.ca/poison/?section=species&id=117 (Accessed 16 October 2009).
- European elder. Canadian Poisonous Plants Information System. Available at: http://www.cbif.gc.ca/pls/pp/ppack.jump?p_null=all&p_psn=121&p_type=all&p_sci=comm&p_x=px (Accessed 16 October 2009).
- Raus K, Pleschka S, Klein P, Schoop R, Fisher P. Effect of an echinacea-based hot drink versus oseltamivir in Influenza treatment: a randomized, double-blind, double-dummy, multicenter, noninferiority clinical trial. . Curr Ther Res Clin Exp. 2015;20;77:6 PubMed
- Ramachandran A, Antala D, Pudasainee P, Panginikkod S, Gupta H. A Plausible Association Between the Use of Elderberry and Autoimmune Hepatitis. Cureus 2022;14(4):e24250. PubMed
- Agarwal N, Mangla A. Elderberry interaction with pazopanib in a patient with soft-tissue sarcoma: A case report and literature review. Mol Clin Oncol 2024;20(5):36. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC