Elderberry + Probiotics Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Elderberry + Probiotics against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Elderberry + Probiotics is a dietary supplement by Ancient Nutrition with 4 active ingredients. Its ingredients are commonly taken for blood sugar support, weight management, digestive upset.Based on those ingredients, 464 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bacillus subtilis, Apple Cider Vinegar, Elderberry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Elderberry + Probiotics by Ancient Nutrition
Ask about any prescription or over-the-counter medication and we check it for interactions with Elderberry + Probiotics by Ancient Nutrition — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Elderberry + Probiotics by Ancient Nutrition
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This formula contains 4 active ingredients: apple cider vinegar, two forms of elderberry (one fermented), and Bacillus subtilis (a beneficial bacteria). Apple cider vinegar is a sour liquid made from apples.
Elderberry comes from the elder plant's ripe fruit and is fermented in one of the forms here. Bacillus subtilis is a live probiotic organism that's meant to support gut health.
The capsule also holds rice fiber and hypromellose (a plant-based coating material) as inactive ingredients.
Does it work?
Moderate evidence
For most of the conditions these ingredients are marketed for — hay fever, cold and flu, heart health, focus, and general energy — the evidence we hold rates them as having insufficient reliable evidence. The one exception is Bacillus subtilis for antibiotic-associated diarrhea, which is rated possibly effective, meaning some evidence exists but it's not conclusive.
If you're considering this product for a specific health goal, your doctor or pharmacist can discuss what the current research shows.
How safe is it?
Well-documented data
Elderberry extract from ripe, properly cooked fruit is generally well tolerated. Apple cider vinegar in small amounts (like in food) is also usually fine, but large doses taken long-term can cause serious issues — one documented case involved low potassium, bone loss, and kidney effects after someone drank 250 mL daily for 6 years.
Bacillus subtilis is generally well tolerated in healthy people, though quality and safety can vary by product. For pregnancy, elderberry supplements are not recommended because there isn't enough safety data; the same goes for breastfeeding.
Bacillus subtilis also lacks enough pregnancy and breastfeeding data, so it's wise to check with your doctor or pharmacist before using this product if you're pregnant or nursing.
Meds to double-check
Moderate interaction found
Before taking this product, check with your doctor or pharmacist if you take digoxin (Lanoxin) or any heart medication, diuretic drugs (water pills), insulin, diabetes medications, antibiotic drugs, immunosuppressants, or pazopanib (Votrient). The severity ranges from Moderate to Minor, with the most serious being the interaction with digoxin and diuretics.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This combination may be useful if you're looking to support gut health with probiotics and want the benefits of elderberry, but the apple cider vinegar content creates several medication interactions you'll want to rule out first — especially if you take a heart medication, blood pressure pill, diabetes drug, or immune-suppressing medication. Talk with your doctor or pharmacist about your medications before you start.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 4 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 24, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Elderberry + Probiotics, straight from the product label.
| Brand | Ancient Nutrition |
|---|---|
| Barcode (UPC) | 816401025234 |
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jan 24, 2024 |
| DSLD ID | 305765 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Elderberry + Probiotics by Ancient Nutrition, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Apple Cider Vinegar | 0 NP | -- |
| Elderberry | 0 NP | -- |
| fermented Elderberry blend | 730 mg | -- |
| Bacillus subtilis | 20 mg | -- |
| Elderberry, Fermented | 0 NP | -- |
Other ingredients: Rice Fiber, Hypromellose
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Formulated for maximum absorption Immune system & digestive support
Color and odor may vary from lot to lot.
FDA Statement of Identity
Whole Food Dietary Supplement
Suggested/Recommended/Usage/Directions
Suggested use: adults take 2 capsules per day.
Precautions
Warning: if you are pregnant, nursing, allergic, have a medical condition, or taking any medications, consult a doctor before using this or any other dietary supplement.
Do not use if inner safety seal is broken or missing.
Keep out of reach of children.
Notice: use this product as a food supplement only. Do not use for weight reduction.
Storage
Store in a cool, dry place.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Elderberry + Probiotics by Ancient Nutrition label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Elderberry + Probiotics by Ancient Nutrition
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Fermented Elderberry blend
Bacillus subtilis
Interacts with182 drugs
Bacillus subtilis is a spore-forming probiotic bacterium found in soil and some fermented foods, and it is used mainly to support gut health and diges...
Bacillus subtilis monograph & interactionsOther (inactive) ingredients: Rice Fiber, Hypromellose. These complete the product’s ingredient list but are not active constituents.
Elderberry + Probiotics by Ancient Nutrition Drug Interactions
HelloPharmacist Interaction Report
Elderberry + Probiotics by Ancient Nutrition does interact with several medication types, primarily through its apple cider vinegar and elderberry content.
The most serious documented concern is a Moderate-severity interaction between apple cider vinegar and digoxin (Lanoxin, a heart rhythm medication) — apple cider vinegar may lower potassium levels, which can increase the risk of toxicity with digoxin.
Read the full breakdown — every affected drug type, severity by severity
Apple cider vinegar also carries Moderate-severity interactions with diuretic drugs (water pills) and insulin, both related to the risk of low potassium (hypokalemia), and a Minor interaction with other diabetes medications, where it might lower blood sugar further. Elderberry has Moderate-severity interactions with immunosuppressant drugs (medications that quiet the immune system after transplant or for autoimmune conditions) and with pazopanib (Votrient), a cancer drug.
Bacillus subtilis, the probiotic strain in this formula, has a Moderate interaction with antibiotic drugs — taking them at the same time may reduce the probiotic's effectiveness.
Altogether, these interactions span 464 individual medications. The remedy is straightforward: use the medication checker on this page to search your exact medications before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Elderberry + Probiotics?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Elderberry + Probiotics interact with 464 drugs. Click any drug to see the details.
3 of the 4 ingredients in Elderberry + Probiotics interact with drugs. Each result below shows which ingredient is responsible. Bacillus subtilis Apple Cider Vinegar Elderberry
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Elderberry + Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Elderberry, FermentedImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry, Fermented + 6-mercaptopurine interactionAbrocitinibCibinqo
How Abrocitinib interacts with Elderberry + Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Elderberry, FermentedImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry, Fermented + Abrocitinib interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Elderberry + Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Apple Cider VinegarDiuretic Drugs Moderate
Interaction Summary
Theoretically, concomitant use of apple cider vinegar with diuretic drugs might increase the risk of hypokalemia.
Read the full Apple Cider Vinegar + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Pamabrom, PyrilamineMidol Max Strength PMS, Pamprin, Pamprin ES
How Acetaminophen, Pamabrom, Pyrilamine interacts with Elderberry + Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Apple Cider VinegarDiuretic Drugs Moderate
Interaction Summary
Theoretically, concomitant use of apple cider vinegar with diuretic drugs might increase the risk of hypokalemia.
Read the full Apple Cider Vinegar + Acetaminophen, Pamabrom, Pyrilamine interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Elderberry + Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Apple Cider VinegarDiuretic Drugs Moderate
Interaction Summary
Theoretically, concomitant use of apple cider vinegar with diuretic drugs might increase the risk of hypokalemia.
Read the full Apple Cider Vinegar + Acetazolamide interactionAdalimumabHumira
How Adalimumab interacts with Elderberry + Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Elderberry, FermentedImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry, Fermented + Adalimumab interactionAdalimumab-adazHyrimoz
How Adalimumab-adaz interacts with Elderberry + Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Elderberry, FermentedImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry, Fermented + Adalimumab-adaz interactionAdalimumab-adbmCyltezo
How Adalimumab-adbm interacts with Elderberry + Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Elderberry, FermentedImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry, Fermented + Adalimumab-adbm interactionAdalimumab-afzbAbrilada
How Adalimumab-afzb interacts with Elderberry + Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Elderberry, FermentedImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry, Fermented + Adalimumab-afzb interactionAdalimumab-attoAmjevita
How Adalimumab-atto interacts with Elderberry + Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Elderberry, FermentedImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry, Fermented + Adalimumab-atto interactionAdalimumab-bwwdHadlima
How Adalimumab-bwwd interacts with Elderberry + Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Elderberry, FermentedImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry, Fermented + Adalimumab-bwwd interactionAdalimumab-fkjpHulio
How Adalimumab-fkjp interacts with Elderberry + Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Elderberry, FermentedImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry, Fermented + Adalimumab-fkjp interactionAlefaceptAmevive
How Alefacept interacts with Elderberry + Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Elderberry, FermentedImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry, Fermented + Alefacept interactionAlemtuzumabCampath
How Alemtuzumab interacts with Elderberry + Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Elderberry, FermentedImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry, Fermented + Alemtuzumab interactionAmikacinAmikin, Arikayce
How Amikacin interacts with Elderberry + Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Bacillus SubtilisAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis + Amikacin interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Elderberry + Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Apple Cider VinegarDiuretic Drugs Moderate
Interaction Summary
Theoretically, concomitant use of apple cider vinegar with diuretic drugs might increase the risk of hypokalemia.
Read the full Apple Cider Vinegar + Amiloride, Hydrochlorothiazide interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Elderberry + Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Apple Cider VinegarDiuretic Drugs Moderate
Interaction Summary
Theoretically, concomitant use of apple cider vinegar with diuretic drugs might increase the risk of hypokalemia.
Read the full Apple Cider Vinegar + Ammonium Chloride interactionAmoxicillinAmix, Amoram, Amoxident, Amoxil Capsules, Amoxil Injection, Galenamox +3 more
How Amoxicillin interacts with Elderberry + Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Bacillus SubtilisAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis + Amoxicillin interactionAmoxicillin VeterinaryBiomox
How Amoxicillin Veterinary interacts with Elderberry + Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Bacillus SubtilisAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis + Amoxicillin Veterinary interactionAmoxicillin, Clavulanate PotassiumAugmentin, Augmentin '125/31 SF', Augmentin '250/62 SF', Augmentin XR, Augmentin-Duo 400/57, Clavulin
How Amoxicillin, Clavulanate Potassium interacts with Elderberry + Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Bacillus SubtilisAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis + Amoxicillin, Clavulanate Potassium interactionAmoxicillin, Omeprazole Magnesium, RifabutinTalicia
How Amoxicillin, Omeprazole Magnesium, Rifabutin interacts with Elderberry + Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Bacillus SubtilisAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionAmphotericin, TetracyclineMysteclin-F
How Amphotericin, Tetracycline interacts with Elderberry + Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Bacillus SubtilisAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis + Amphotericin, Tetracycline interactionAmpicillinOmnipen, Omnipen-N, Penbritin, Principen, Rimacillin
How Ampicillin interacts with Elderberry + Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Bacillus SubtilisAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis + Ampicillin interactionAmpicillin, SulbactamUnasyn
How Ampicillin, Sulbactam interacts with Elderberry + Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Bacillus SubtilisAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis + Ampicillin, Sulbactam interactionAnifrolumab-fniaSaphnelo
How Anifrolumab-fnia interacts with Elderberry + Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Elderberry, FermentedImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry, Fermented + Anifrolumab-fnia interactionAntithymocyte GlobulinThymoglobulin
How Antithymocyte Globulin interacts with Elderberry + Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Elderberry, FermentedImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry, Fermented + Antithymocyte Globulin interactionAtenolol, ChlortalidoneAtenixCo, Tenoret 50, Totaretic
How Atenolol, Chlortalidone interacts with Elderberry + Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Apple Cider VinegarDiuretic Drugs Moderate
Interaction Summary
Theoretically, concomitant use of apple cider vinegar with diuretic drugs might increase the risk of hypokalemia.
Read the full Apple Cider Vinegar + Atenolol, Chlortalidone interactionAtenolol, ChlorthalidoneTenoretic
How Atenolol, Chlorthalidone interacts with Elderberry + Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Apple Cider VinegarDiuretic Drugs Moderate
Interaction Summary
Theoretically, concomitant use of apple cider vinegar with diuretic drugs might increase the risk of hypokalemia.
Read the full Apple Cider Vinegar + Atenolol, Chlorthalidone interactionAtezolizumabTecentriq
How Atezolizumab interacts with Elderberry + Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Elderberry, FermentedImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry, Fermented + Atezolizumab interactionAvibactam Sodium, CeftazidimeAvycaz
How Avibactam Sodium, Ceftazidime interacts with Elderberry + Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Bacillus SubtilisAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis + Avibactam Sodium, Ceftazidime interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Elderberry + Probiotics with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Bacillus subtilis
Antibiotic Drugs
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B. subtilis.
Since B. subtilis preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. subtilis preparations by at least 2 hours.
Apple Cider Vinegar
Digoxin (Lanoxin)
Theoretically, concomitant use of apple cider vinegar with digoxin might increase the risk of cardiac toxicity.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. Theoretically, overuse of apple cider vinegar could decrease potassium levels, increasing the risk of toxicity with digoxin.
Diuretic Drugs
Theoretically, concomitant use of apple cider vinegar with diuretic drugs might increase the risk of hypokalemia.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. There is some concern that people taking apple cider vinegar along with potassium depleting diuretics might have an increased risk for hypokalemia.
Insulin
Theoretically, concomitant use of apple cider vinegar with insulin might increase the risk of hypokalemia.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. Theoretically, overuse of apple cider vinegar concomitantly with insulin might increase the risk of hypokalemia.
Antidiabetes Drugs
Theoretically, taking apple cider vinegar with antidiabetes drugs might increase the risk of hypoglycemia.
Apple cider vinegar might reduce fasting and postprandial blood glucose levels and decrease gastric emptying in people with diabetes. However, not all research agrees. Theoretically, it might have additive effects on glucose levels when used with antidiabetes drugs.
Elderberry
Immunosuppressants
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Elderberry has immunostimulant activity, increasing the production of cytokines, including interleukin and tumor necrosis factor.
Pazopanib (Votrient)
Theoretically, elderberry might interact with pazopanib, potentially increasing the risk of adverse effects.
Brand information
Manufacturer and brand details for Elderberry + Probiotics, from the product label.
Ancient Nutrition
See all Ancient Nutrition products- Name
- Ancient Nutrition, LLC
- Street Address
- 3480 Summertown Hwy
- City
- Summertown
- State
- TN
- ZipCode
- 38483
- Web Address
- www.AncientNutrition.com
Elderberry + Probiotics by Ancient Nutrition: Common Questions
Does Elderberry + Probiotics by Ancient Nutrition interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this while I'm pregnant?
What's the apple cider vinegar in here doing?
Does Bacillus subtilis actually work?
What if I'm taking antibiotics at the same time?
Is this safe to use long-term?
Can I breastfeed while taking this?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Elderberry + Probiotics is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Elderberry + Probiotics’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Apple Cider Vinegar
Interacts with 162 drugsApple cider vinegar is a fermented apple product that many people use hoping to help with blood sugar, weight, or digestion. The evidence for most of these uses is limited and mixed, and the...
Read the full Apple Cider Vinegar monograph → Herb & supplement monographElderberry
Interacts with 121 drugsElderberry is a popular herbal supplement, mainly taken to help with colds and flu. Some small studies suggest it may modestly shorten cold or flu symptoms, but the evidence is limited and n...
Read the full Elderberry monograph → Herb & supplement monographBacillus Subtilis
Interacts with 182 drugsBacillus subtilis is a spore-forming probiotic bacterium found in soil and some fermented foods, and it is used mainly to support gut health and digestion. Early research is promising for ce...
Read the full Bacillus Subtilis monograph →Sources & How We Checked
Elderberry + Probiotics's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 27 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Apple Cider Vinegar 11 references
- Lhotta K, Hofle G, Gasser R, Finkenstedt G. Hypokalemia, hyperreninemia, and osteoporosis in a patient ingesting large amounts of cider vinegar. Nephron 1998;80:242-3. PubMed
- Hill LL, Woodruff LH, Foote JC, Barreto-Alcoba M. Esophageal injury by apple cider vinegar tablets and subsequent evaluation of products. J Am Diet Assoc 2005;105:1141-4. PubMed
- Hlebowicz J, Darwiche G, Björgell O, Almér LO. Effect of apple cider vinegar on delayed gastric emptying in patients with type 1 diabetes mellitus: a pilot study. BMC Gastroenterol 2007;7:46. PubMed
- Johnston CS, Kim CM, Buller AJ. Vinegar improves insulin sensitivity to a high-carbohydrate meal in subjects with insulin resistance or type 2 diabetes. Diabetes Care 2004;27:281-2. PubMed
- Lhotta, K., Hofle, G., Gasser, R., and Finkenstedt, G. Hypokalemia, hyperreninemia and osteoporosis in a patient ingesting large amounts of cider vinegar. Nephron 1998;80(2):242-243. PubMed
- Bunick CG, Lott JP, Warren CB, et al. Chemical burn from topical apple cider vinegar. J Am Acad Dermatol 2012;67(4):e143-4. PubMed
- Feldstein S, Afshar M, Krakowski AC. Chemical Burn from Vinegar Following an Internet-based Protocol for Self-removal of Nevi. J Clin Aesthet Dermatol. 2015 Jun;8(6):50.
- Luu LA, Flowers RH, Kellams AL, et al. Apple cider vinegar soaks [0.5%] as a treatment for atopic dermatitis do not improve skin barrier integrity. Pediatr Dermatol. 2019;36(5):634-639. PubMed
- Hadi A, Pourmasoumi M, Najafgholizadeh A, Clark CCT, Esmaillzadeh A. The effect of apple cider vinegar on lipid profiles and glycemic parameters: a systematic review and meta-analysis of randomized clinical trials. BMC Complement Med Ther 2021;21(1):179. PubMed
- Feise NK, Johnston CS. Commercial vinegar tablets do not display the same physiological benefits for managing postprandial glucose concentrations as liquid vinegar. J Nutr Metab 2020;2020:9098739. PubMed
- Gheflati A, Bashiri R, Ghadiri-Anari A, Reza JZ, Kord MT, Nadjarzadeh A. The effect of apple vinegar consumption on glycemic indices, blood pressure, oxidative stress, and homocysteine in patients with type 2 diabetes and dyslipidemia: A randomized contro
Elderberry 6 references
- Barak V, Halperin T, Kalickman I. The effect of Sambucol, a black elderberry-based, natural product, on the production of human cytokines: I. Inflammatory cytokines. Eur Cytokine Netw 2001;12:290-6..
- Elderberry (Sambucus species). The Poison Plant Patch, Novia Scotia Museum, 2007. Available at: http://museum.gov.ns.ca/poison/?section=species&id=117 (Accessed 16 October 2009).
- European elder. Canadian Poisonous Plants Information System. Available at: http://www.cbif.gc.ca/pls/pp/ppack.jump?p_null=all&p_psn=121&p_type=all&p_sci=comm&p_x=px (Accessed 16 October 2009).
- Raus K, Pleschka S, Klein P, Schoop R, Fisher P. Effect of an echinacea-based hot drink versus oseltamivir in Influenza treatment: a randomized, double-blind, double-dummy, multicenter, noninferiority clinical trial. . Curr Ther Res Clin Exp. 2015;20;77:6 PubMed
- Ramachandran A, Antala D, Pudasainee P, Panginikkod S, Gupta H. A Plausible Association Between the Use of Elderberry and Autoimmune Hepatitis. Cureus 2022;14(4):e24250. PubMed
- Agarwal N, Mangla A. Elderberry interaction with pazopanib in a patient with soft-tissue sarcoma: A case report and literature review. Mol Clin Oncol 2024;20(5):36. PubMed
Bacillus Subtilis 10 references
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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