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Dietary supplement

Eye Nourish Plus Ingredients & Drug Interactions

by Carotec

Softgel Capsule Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Eye Nourish Plus is a dietary supplement by Carotec with 3 active ingredients. Its ingredients are commonly taken for eye health, age-related macular degeneration, cataract prevention.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are MaquiBright, Zeaxanthin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Eye Nourish Plus by Carotec

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Eye Nourish Plus contains 3 active ingredients: lutein, zeaxanthin, and maqui berry extract (MaquiBright). Lutein and zeaxanthin are yellow pigments that accumulate in the retina and may support eye health as you age.

Maqui is a fruit extract included for additional antioxidant support. The softgels also contain inactive ingredients including gelatin, coconut oil, medium-chain triglycerides, and several other excipients that help deliver and stabilize the active components.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: eye health and vision support.
  • We looked for evidence on: Age-related macular degeneration (AMD), Asthenopia (eye strain), Cataracts, Dry eye, Diabetic retinopathy, Glaucoma — and 4 related terms.
  • The strongest evidence on file: Lutein is rated "Possibly Effective" for Age-related macular degeneration (AMD) (Natural Medicines).
  • Also on file: Lutein is rated "Possibly Effective" for Cataracts.
  • Also on file: Zeaxanthin is rated "Possibly Effective" for Age-related macular degeneration (AMD).

Lutein is possibly effective for age-related macular degeneration (AMD) and cataracts, according to the evidence we hold, though it hasn't shown benefit for retinitis pigmentosa or other retinal conditions in preterm infants. Zeaxanthin is also possibly effective for AMD.

Maqui berry extract has insufficient evidence to establish whether it helps with dry eye, blood sugar control, or overall psychological well-being. The data on these ingredients for other eye conditions remains limited.

The evidence, ingredient by ingredient Lutein Maqui Zeaxanthin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lutein from food and at typical supplement doses is generally well tolerated, with research showing doses up to 20 mg daily have not caused adverse effects. However, the safety data on high-dose lutein supplements during pregnancy and breastfeeding isn't complete — if you're pregnant or nursing, discuss supplement use with your doctor.

Zeaxanthin is also generally well tolerated at standard doses, though safety in concentrated supplement form during pregnancy and breastfeeding hasn't been fully studied. Maqui berry extract's safety as a supplement hasn't been well established, so use caution — especially in pregnancy and breastfeeding — and check with your doctor before taking it.

Side effects, ingredient by ingredient Lutein Maqui Zeaxanthin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 3 matched ingredients can interact with medications — Maqui, Zeaxanthin.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take any antidiabetes drug (including insulin or oral diabetes medications), check it with the interaction tool on this page — zeaxanthin and maqui may theoretically raise the risk of low blood sugar when combined with these medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Eye Nourish Plus may be worth considering if you're concerned about age-related macular degeneration or cataracts. If you take any diabetes medication, check your exact drug with our interaction tool before starting.

Pregnancy and breastfeeding call for a conversation with your own doctor or pharmacist, since long-term safety data on these concentrated supplements is still incomplete.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Eye Nourish Plus, straight from the product label.

Brand Carotec
Net contents 60 Softgel(s)
Market status On market
Date entered into DSLD Jan 23, 2023
DSLD ID 282132
Product type Other Combinations
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Eye Nourish Plus by Carotec, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Softgel(s)
Maximum serving Sizes:
2 Softgel(s)
Servings per container
30
IngredientAmount% DV
Calories5 Calorie(s)--
Total Fat0.5 Gram(s)1%
Lutein20 mg--
MaquiBright60 mg--
Zeaxanthin10 mg--

Other ingredients: Gelatin, Coconut Oil, Medium Chain Triglycerides, Glycerin, Water, Purified, Sunflower Oil, Riboflavin, Sunflower Lecithin, yellow Beeswax, natural Tocopherols

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: Take two (2) softgels daily, preferably with a meal.

Precautions

Warning: Keep out of reach of children.

If you are pregnant, nursing or taking medication, consult your doctor before use.

Discontinue use and consult your doctor if adverse reactions occur.

Contains: Tree nut (coconut)

Brand IP Statement(s)

Lutemax 2020 and OmniXan RS are registered trademarks of OmniActive Health Technologies, Ltd. MaquiBright is a registered trademark of Maqui New Life S.A., Chile and Oryza Oil & Fat Chemical Co., LTD., Japan

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

See for yourself

Eye Nourish Plus by Carotec label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Eye Nourish Plus by Carotec

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Lutein

No known
interactions
20 mg per serving Form: Lutemax 2020 Marigold flower extract

Lutein is a plant-based antioxidant pigment that concentrates in the eye, and the best evidence suggests it (often combined with zeaxanthin) may help...

Lutein monograph & interactions

MaquiBright

Interacts with
86 drugs
60 mg per serving Form: Aristotelia chilensis Berry Extract

Maqui is a dark purple berry from Chile that is very rich in antioxidant plant pigments called anthocyanins. Early research suggests it may help with...

MaquiBright monograph & interactions

Zeaxanthin

Interacts with
86 drugs
10 mg per serving Form: Lutemax 2020 Marigold flower extract, OmniXan RS

Zeaxanthin is a carotenoid pigment that, along with lutein, concentrates in the macula of the eye and may help support long-term eye health. The stron...

Zeaxanthin monograph & interactions

Other (inactive) ingredients: Gelatin, Coconut Oil, Medium Chain Triglycerides, Glycerin, Water, Purified, Sunflower Oil, Riboflavin, Sunflower Lecithin, Yellow Beeswax, Natural Tocopherols. These complete the product’s ingredient list but are not active constituents.

Interaction report

Eye Nourish Plus by Carotec Drug Interactions

Want to check YOUR meds against Eye Nourish Plus?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Eye Nourish Plus with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

MaquiBright1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, maqui fruit extract may increase the risk of hypoglycemia when used with antidiabetes drugs.
Animal research shows that maqui berry reduces fasting blood glucose. However, maqui berry extract taken orally, either as a single dose or daily for 3 months, does not decrease fasting blood glucose in prediabetic patients. It is unknown whether it might reduce blood glucose levels in patients with diabetes.

Likelihood Possible Evidence B

Zeaxanthin1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking zeaxanthin with antidiabetes drugs might increase the risk of hypoglycemia.
In an animal diabetic model, zeaxanthin has hypoglycemic effects. However, population research has found that increasing intake of dietary zeaxanthin plus lutein does not decrease the risk of developing type 2 diabetes.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Eye Nourish Plus, from the product label.

Carotec

See all Carotec products
Name
Carotec, Inc.
Street Address
P.O. Box 9919
City
Naples
State
FL
ZipCode
34101
Phone Number
1-800-522-4279
Web Address
www.carotec.com
Pharmacist Counseling Corner

Eye Nourish Plus by Carotec: Common Questions

Does Eye Nourish Plus by Carotec interact with any medications?
Yes. Based on its ingredients, Eye Nourish Plus has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Eye Nourish Plus contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does lutein really help with cataracts and age-related macular degeneration?
Both lutein and zeaxanthin in this product are possibly effective for AMD and cataracts based on the evidence we hold. That means there's reasonable support, but it's not ironclad — talk to your eye doctor about whether this fits your situation.
What's maqui berry extract, and does it actually work for dry eye?
Maqui is a South American fruit extract with antioxidant properties. For dry eye, however, we don't have enough reliable evidence to say whether it works. It's included here for general antioxidant support, but don't count on it as a dry-eye treatment.
Can I take this if I'm pregnant or breastfeeding?
Lutein and zeaxanthin are rated likely safe in pregnancy and lactation, but high-dose supplement safety hasn't been fully studied. Maqui's safety in pregnancy and breastfeeding is unclear. Talk it over with your doctor or pharmacist before starting — they know your situation best.
Are there any fillers in these softgels?
The softgels contain inactive ingredients like gelatin, coconut oil, medium-chain triglycerides, glycerin, sunflower oil, and a few others that stabilize and deliver the active ingredients. These are standard excipients in softgel formulations.
What dose of lutein is in here, and is it safe?
The product facts don't specify the dose per softgel. Research shows doses up to 20 mg daily of lutein haven't caused adverse effects, but check the label for the exact amount in each capsule, and ask your pharmacist if you have questions about the dose for your needs.
I take a diabetes medication — is this safe for me?
Both the maqui and zeaxanthin in this product may theoretically increase the risk of low blood sugar when combined with diabetes drugs. Check your specific medication with the interaction tool on this page, and confirm with your doctor or pharmacist before you start.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Eye Nourish Plus is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Eye Nourish Plus label
Sources

Sources & How We Checked

Eye Nourish Plus's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 9 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lutein 2 references
  1. Brown L, Rimm EB, Seddon JM, et al. A prospective study of carotenoid intake and risk of cataract extraction in US men. Am J Clin Nutr 1999;70:517-24. PubMed
  2. Chasan-Taber L, Willett WC, Seddon JM, et al. A prospective study of carotenoid and vitamin A intakes and risk of cataract extraction in US women. Am J Clin Nutr 1999;70:509-16. PubMed

See these in context on the Lutein monograph →

Maqui 3 references
  1. Alvarado JL, Leschot A, Olivera-Nappa Á, et al. Delphinidin-rich maqui berry extract (Delphinol®) lowers fasting and postprandial glycemia and insulinemia in prediabetic individuals during oral glucose tolerance tests. Biomed Res Int. 2016;2016:9070537. PubMed
  2. Alvarado J, Schoenlau F, Leschot A, Salgad AM, Vigil Portales P. Delphinol® standardized maqui berry extract significantly lowers blood glucose and improves blood lipid profile in prediabetic individuals in three-month clinical trial. Panminerva Med. 2016
  3. Hidalgo J, Flores C, Hidalgo MA, et al. Delphinol® standardized maqui berry extract reduces postprandial blood glucose increase in individuals with impaired glucose regulation by novel mechanism of sodium glucose cotransporter inhibition. Panminerva Med.

See these in context on the Maqui monograph →

Zeaxanthin 4 references
  1. Montonen J, Knekt P, Jarvinen R, Reunanen A. Dietary antioxidant intake and risk of type 2 diabetes. Diabetes Care 2004;27:362-6. PubMed
  2. Leermakers ET, Darweesh SK, Baena CP, et al. The effects of lutein on cardiometabolic health across the life course: a systematic review and meta-analysis. Am J Clin Nutr 2016;103(2):481-94. PubMed
  3. Kou L, Du M, Zhang C, Dai Z, Li X, Zhang B. The Hypoglycemic, Hypolipidemic, and Anti-Diabetic Nephritic Activities of Zeaxanthin in Diet-Streptozotocin-Induced Diabetic Sprague Dawley Rats. Appl Biochem Biotechnol 2017;182(3):944-955. PubMed
  4. Xu X, Zhao X, Berde Y, Low YL, Kuchan MJ. Milk and Plasma Lutein and Zeaxanthin Concentrations in Chinese Breast-Feeding Mother-Infant Dyads With Healthy Maternal Fruit and Vegetable Intake. J Am Coll Nutr 2019;38(2):179-184. PubMed

See these in context on the Zeaxanthin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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