Fenugreek Ingredients & Drug Interactions
by Herb Pharm
What is this page for?
First and foremost: checking Fenugreek against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Fenugreek is a dietary supplement by Herb Pharm with 1 active ingredient. Its ingredients are commonly taken for blood sugar control, boosting breast milk supply, high cholesterol.Based on those ingredients, 389 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Fenugreek Seed Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Fenugreek by Herb Pharm
Ask about any prescription or over-the-counter medication and we check it for interactions with Fenugreek by Herb Pharm — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Fenugreek by Herb Pharm
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains 1 active ingredient: fenugreek seed extract, the concentrated form of fenugreek seeds. It's prepared in a liquid form with cane alcohol and distilled water as inactive ingredients.
Does it work?
Moderate evidence
Fenugreek is rated Possibly Effective for sexual dysfunction and dysmenorrhea (painful periods), and Possibly Effective for diabetes support. That means there's some clinical evidence backing these uses, but the research isn't conclusive yet.
If you're considering it for one of these purposes, it's worth a conversation with your doctor about whether the evidence fits your situation.
How safe is it?
Well-documented data
Fenugreek seed is generally well tolerated in food amounts, but supplement doses may cause side effects. The most common ones are abdominal pain, bloating, diarrhea, indigestion, gas, low blood sugar, and nausea.
Rare but serious allergic reactions—including severe swelling (angioedema), breathing problems (bronchospasm), and shock—have been reported. If you're allergic to peanuts or chickpeas, you may react to fenugreek too.
During pregnancy, fenugreek is rated Likely Unsafe because it may affect the uterus and medicinal doses should be avoided. If you take it near delivery, your newborn may have an unusual body odor.
During breastfeeding, the evidence is limited—it's often used to boost milk supply, but you'll want to discuss it with your provider first before starting.
Meds to double-check
Moderate interaction found
Check with your doctor or pharmacist before using this product if you take blood thinners (warfarin or other anticoagulants), antiplatelet drugs, diabetes medications, theophylline, metoprolol, phenytoin, or sildenafil. All of these interactions are Moderate in severity.
Your provider can help you decide if it's right for you and whether your dose or timing needs adjusting.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Fenugreek may help with sexual dysfunction, painful periods, or blood sugar management, but it interacts with blood thinners and several other medications. If you take warfarin, diabetes drugs, or theophylline, talk with your own doctor or pharmacist before starting.
Avoid it in pregnancy and discuss it with your provider if you're breastfeeding.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 24, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Fenugreek, straight from the product label.
| Brand | Herb Pharm |
|---|---|
| Barcode (UPC) | 090700001513 |
| Net contents | 4 Fluid Ounce(s); 120 mL |
| Market status | On market |
| Date entered into DSLD | Jan 24, 2024 |
| DSLD ID | 307506 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Organic, Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Fenugreek by Herb Pharm, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Fenugreek Seed Extract | 614 mg | -- |
Other ingredients: Cane Alcohol, Water, Distilled
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested use Shake well before using Adults: Add 1 squeeze of the dropper bulb to 2 oz. of water or juice, 2 to 5 times per day. Best taken between meals.
Precautions
Caution: Seek expert medical advice before taking during pregnancy.
Keep out of the reach of children
Storage
Store away from heat & light
Formula
Trigonella foenum-graecum
Fenugreek liquid extract
We prepare our Fenugreek Extract from the seed of certified organically grown Trigonella foenum-graecum plants.
Formulation
System restoration Reproductive
USDA Organic
Gluten-free
We prepare our Fenugreek Extract from the seed of certified organically grown Trigonella foenum-graecum plants. Certified organic by Organic Certifiers
Seals/Symbols
USDA Organic
FDA Statement of Identity
Herbal Supplement
FDA Disclaimer Statement
This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Fenugreek by Herb Pharm label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Fenugreek by Herb Pharm
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size0.7 mL Dosage formLiquid Servings per container168 Amounts shown are per serving.
Fenugreek Seed Extract
Interacts with389 drugs
Fenugreek is a common kitchen spice that is also taken as a supplement, mainly for blood sugar, cholesterol, and to support breast milk production. So...
Fenugreek Seed Extract monograph & interactionsOther (inactive) ingredients: Cane Alcohol, Water, Distilled. These complete the product’s ingredient list but are not active constituents.
Fenugreek by Herb Pharm Drug Interactions
HelloPharmacist Interaction Report
Herb Pharm's fenugreek liquid does interact with medications, and the concerns span several important drug types.
The most serious interaction is with blood thinners (anticoagulants) like warfarin—fenugreek's constituents may have blood-thinning effects themselves, which could add up and raise your bleeding risk.
Read the full breakdown — every affected drug type, severity by severity
Beyond that, fenugreek can lower blood sugar (hypoglycemia) if you're already taking diabetes medications, and it may reduce how well certain other drugs work: theophylline (a breathing medication), clopidogrel (an antiplatelet drug), metoprolol (a blood pressure medication), phenytoin (an anti-seizure drug), and sildenafil (Viagra). It could also theoretically boost the blood-thinning effect of antiplatelet drugs more broadly.
All of these interactions are rated Moderate in severity.
Additionally, we could not check fenugreek itself beyond what the seed extract tells us. Altogether, these interactions span 389 individual medications.
If you take any of these drug types—or any prescription medication at all—run it through the checker below before you start this product. Your own doctor or pharmacist can review your exact medications against these findings.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Fenugreek?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Fenugreek interact with 389 drugs. Click any drug to see the details.
1 of the 1 ingredient in Fenugreek interact with drugs. Each result below shows which ingredient is responsible. Fenugreek Seed Extract
Linagliptin, Metformin HydrochlorideJentadueto XR
How Linagliptin, Metformin Hydrochloride interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek Seed Extract + Linagliptin, Metformin Hydrochloride interactionLiraglutideVictoza
How Liraglutide interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek Seed Extract + Liraglutide interactionLiraglutide RecombinantSaxenda
How Liraglutide Recombinant interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek Seed Extract + Liraglutide Recombinant interactionLixisenatideAdlyxin
How Lixisenatide interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek Seed Extract + Lixisenatide interactionMephenytoinMesantoin
How Mephenytoin interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractPhenytoin (dilantin) Moderate
Interaction Summary
Theoretically, fenugreek might decrease plasma levels of phenytoin.
Read the full Fenugreek Seed Extract + Mephenytoin interactionMetforminGlucophage, Metformin
How Metformin interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek Seed Extract + Metformin interactionMetformin HydrochlorideRiomet ER
How Metformin Hydrochloride interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek Seed Extract + Metformin Hydrochloride interactionMetformin XrGlucophage XR
How Metformin Xr interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek Seed Extract + Metformin Xr interactionMetformin, LinagliptinJentadueto
How Metformin, Linagliptin interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek Seed Extract + Metformin, Linagliptin interactionMetformin, RosiglitazoneAvandamet
How Metformin, Rosiglitazone interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek Seed Extract + Metformin, Rosiglitazone interactionMetformin, SitagliptinJanumet, Janumet XR
How Metformin, Sitagliptin interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek Seed Extract + Metformin, Sitagliptin interactionMetoprololLopressor, Toprol XL
How Metoprolol interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAntihypertensive Drugs, Metoprolol (toprol) Moderate
Interaction Summary
Fenugreek may also have an additive effect on blood pressure-lowering medications.
Read the full Fenugreek Seed Extract + Metoprolol interactionMiglitolGlyset
How Miglitol interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek Seed Extract + Miglitol interactionMinocyclineAcnamino MR, Aknemin, Amzeeq, Arestin Miscrosperes, Dynacin, Minocin +6 more
How Minocycline interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Minocycline interactionMuraglitazarPargluva
How Muraglitazar interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek Seed Extract + Muraglitazar interactionNadroparinFraxiparine
How Nadroparin interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Nadroparin interactionNaproxenAleve, Anaprox, Anaprox DS, Arthroxen, EC-Naprosyn, Naprelan +7 more
How Naproxen interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Naproxen interactionNaproxen SodiumMidol Extended Relief
How Naproxen Sodium interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Naproxen Sodium interactionNaproxen, PseudoephedrineAleve Cold and Sinus
How Naproxen, Pseudoephedrine interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Naproxen, Pseudoephedrine interactionNaproxen, SumatriptanTreximet
How Naproxen, Sumatriptan interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Naproxen, Sumatriptan interactionNateglinideStarlix
How Nateglinide interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek Seed Extract + Nateglinide interactionNintedanib EsylateOfev
How Nintedanib Esylate interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Nintedanib Esylate interactionNusinersen SodiumSpinraza
How Nusinersen Sodium interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Nusinersen Sodium interactionOmega-3 Fatty Acids (prescription Drug)Lovaza
How Omega-3 Fatty Acids (prescription Drug) interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Omega-3 Fatty Acids (prescription Drug) interactionPazopanibVotrient
How Pazopanib interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Pazopanib interactionPentoxifyllineTrental
How Pentoxifylline interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Pentoxifylline interactionPhenobarbital, PhenytoinDilantin with PB
How Phenobarbital, Phenytoin interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractPhenytoin (dilantin) Moderate
Interaction Summary
Theoretically, fenugreek might decrease plasma levels of phenytoin.
Read the full Fenugreek Seed Extract + Phenobarbital, Phenytoin interactionPhenprocoumonLiquamar
How Phenprocoumon interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Extract + Phenprocoumon interactionPhenytoinDi-Phen, Dilantin, Dilantin Infatabs, Dilantin injection, Dilantin Kapseals, Phenytek
How Phenytoin interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractPhenytoin (dilantin) Moderate
Interaction Summary
Theoretically, fenugreek might decrease plasma levels of phenytoin.
Read the full Fenugreek Seed Extract + Phenytoin interactionPioglitazoneActos
How Pioglitazone interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek Seed Extract + Pioglitazone interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Fenugreek with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Fenugreek Seed Extract
Anticoagulant/Antiplatelet Drugs
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Some of the constituents in fenugreek have antiplatelet effects in animal and in vitro research. However, common fenugreek products might not contain sufficient concentrations of these constituents for clinical effects. A clinical study in patients with coronary artery disease or diabetes shows that taking fenugreek seed powder 2.5 grams twice daily for 3 months does not affect platelet aggregation, fibrinolytic activity, or fibrinogen levels .
Antidiabetes Drugs
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Clinical research shows that fenugreek seed can reduce fasting blood glucose and 2-hour postprandial glucose levels in adults with type 2 diabetes.
Clopidogrel (Plavix)
Theoretically, fenugreek seed might alter the clinical effects of clopidogrel by inhibiting its conversion to the active form.
Animal research shows that fenugreek seed 200 mg/kg daily for 14 days increases the maximum serum concentration of clopidogrel by 21%. It is unclear how this affects the pharmacokinetics of the active metabolite of clopidogrel; however, this study found that concomitant use of fenugreek seed and clopidogrel prolonged bleeding time by an additional 11%.
Metoprolol (Toprol)
Theoretically, fenugreek seed might have additive hypotensive effects when used with metoprolol.
Animal research shows that fenugreek seed 300 mg/kg daily for 2 weeks decreases systolic and diastolic blood pressure by 9% and 11%, respectively, when administered alone, and by 15% and 22%, respectively, when given with metoprolol 10 mg/kg.
Phenytoin (Dilantin)
Theoretically, fenugreek might decrease plasma levels of phenytoin.
Animal research shows that taking fenugreek seeds for 1 week decreases maximum concentrations and the area under the curve of a single dose of phenytoin by 44% and 72%, respectively. This seems to be related to increased clearance. So far, this interaction has not been reported in humans.
Sildenafil (Viagra)
Theoretically, concurrent use of sildenafil and fenugreek might reduce levels and therapeutic effects of sildenafil.
Animal research shows that taking fenugreek seeds for 1 week reduces maximum concentrations and the area under the curve of a single dose of sildenafil by 27% and 48%, respectively. So far, this interaction has not been reported in humans.
Theophylline
Theoretically, fenugreek may reduce the levels and clinical effects of theophylline.
Animal research shows that fenugreek 50 grams daily for 7 days reduces the maximum serum concentration (Cmax) of theophylline by 28% and the area under the plasma drug concentration-time curve (AUC) by 22%.
Warfarin (Coumadin)
Theoretically, fenugreek might have additive effects with warfarin and increase the international normalized ratio (INR).
Some fenugreek constituents have antiplatelet effects, although these might not be present in concentrations that are clinically significant. In one case report, a patient taking warfarin experienced an increased INR when starting to take fenugreek in combination with boldo.
Antihypertensive Drugs
Fenugreek may also have an additive effect on blood pressure-lowering medications. Studies on animals have shown that fenugreek seed can decrease both systolic and diastolic blood pressure by up to 22% when combined with metoprolol. Therefore, it is essential to monitor your blood pressure regularly if you are taking fenugreek and metoprolol together or any other antihypertensive drugs.
Brand information
Manufacturer and brand details for Fenugreek, from the product label.
Herb Pharm
See all Herb Pharm products- Name
- Herb Pharm
- City
- Williams
- State
- OR
- ZipCode
- 97544
- Phone Number
- 800-348-4372
- Web Address
- www.herb-pharm.com
Fenugreek by Herb Pharm: Common Questions
Does Fenugreek by Herb Pharm interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
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What if I'm taking diabetes medication?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Fenugreek is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Fenugreek’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Fenugreek's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 30 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Fenugreek 30 references
- Madar Z, Thorne R. Dietary fiber. Prog Food Nutr Sci 1987;11:153-74.
- Sharma RD, Raghuram TC, Rao NS. Effect of fenugreek seeds on blood glucose and serum lipids in type I diabetes. Eur J Clin Nutr 1990;44:301-6.
- Patil SP, Niphadkar PV, Bapat MM. Allergy to fenugreek (Trigonella foenum graecum). Ann Allergy Asthma Immunol 1997;78:297-300. PubMed
- Lambert J, Cormier J. Potential interaction between warfarin and boldo-fenugreek. Pharmacotherapy 2001;21:509-12. PubMed
- Bordia A, Verma SK, Srivastava KC. Effect of ginger (Zingiber officinale Rosc.) and fenugreek (Trigonella foenumgraecum L.) on blood lipids, blood sugar and platelet aggregation in patients with coronary artery disease. Prostaglandins Leukot Essent Fatty PubMed
- Yalcin SS, Tekinalp G, Ozalp I. Peculiar odor of traditional food and maple syrup urine disease. Pediatr Int 1999;41:108-9. PubMed
- Sewell AC, Mosandl A, Bohles H. False diagnosis of maple syrup urine disease owing to ingestion of herbal tea. N Engl J Med 1999;341:769.. PubMed
- Abdo MS, al-Kafawi AA. Experimental studies on the effect of Trigonella foenum-graecum (abstract). Planta Med 1969;17:14-8.
- Gupta A, Gupta R, Lal B. Effect of Trigonella foenum-graecum (fenugreek) seeds on glycaemic control and insulin resistance in type 2 diabetes mellitus: a double blind placebo controlled study. J Assoc Physicians India 2001;49:1057-61.
- Gabay MP. Galactogogues: medications that induce lactation. J Hum Lact 2002;18:274-9. PubMed
- Chevassus H, Gaillard JB, Farret A, et al. A fenugreek seed extract selectively reduces spontaneous fat intake in overweight subjects. Eur J Clin Pharmacol 2010;66(5):449-55. PubMed
- Turkyilmaz C, Onal E, Hirfanoglu IM, et al. The effect of galactagogue herbal tea on breast milk production and short-term catch-up of birth weight in the first week of life. J Altern Complement Med 2011;17(2):139-42. PubMed
- Swafford S, Berens P. Effect of fenugreek on breast milk volume. Abstract presented at: 5th International Meeting of the Academy of Breastfeeding Medicine; September 11-13,2000, Tucson, Arizona.
- Abdel-Barry, J. A., Abdel-Hassan, I. A., Jawad, A. M., and al Hakiem, M. H. Hypoglycaemic effect of aqueous extract of the leaves of Trigonella foenum-graecum in healthy volunteers. East Mediterr.Health J 2000;6(1):83-88. DOI
- Parvizpur, A., Ahmadiani, A., and Kamalinejad, M. Probable role of spinal purinoceptors in the analgesic effect of Trigonella foenum (TFG) leaves extract. J Ethnopharmacol 3-8-2006;104(1-2):108-112. PubMed
- Mora, A., Herrrera, A., Lopez, C., Dahbi, G., Mamani, R., Pita, J. M., Alonso, M. P., Llovo, J., Bernardez, M. I., Blanco, J. E., Blanco, M., and Blanco, J. Characteristics of the Shiga-toxin-producing enteroaggregative Escherichia coli O104:H4 German ou
- Blanco, J. [Stx2a-producing enteroaggregative Escherichia coli O104:H4-ST678. Microbiological diagnostic already, for this and other STEC/VTEC serotypes!]. Enferm.Infecc.Microbiol.Clin. 2012;30(2):84-89.
- Beutin, L. and Martin, A. Outbreak of Shiga toxin-producing Escherichia coli (STEC) O104:H4 infection in Germany causes a paradigm shift with regard to human pathogenicity of STEC strains. J Food Prot. 2012;75(2):408-418. PubMed
- King LA, Nogareda F, Weill FX, Mariani-Kurkdjian P, Loukiadis E, Gault G, Jourdan-DaSilva N, Bingen E, Macé M, Thevenot D, Ong N, Castor C, Noël H, Van Cauteren D, Charron M, Vaillant V, Aldabe B, Goulet V, Delmas G, Couturier E, Le Strat Y, Combe C, Delm
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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