Full Spectrum CBD 725 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Full Spectrum CBD 725 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Full Spectrum CBD 725 mg is a dietary supplement by Hemp Essentials with 1 active ingredient. Its ingredients are commonly taken for plant-based protein source, heart health support, skin and hair health.Based on those ingredients, 938 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Hemp extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Full Spectrum CBD 725 mg by Hemp Essentials
Ask about any prescription or over-the-counter medication and we check it for interactions with Full Spectrum CBD 725 mg by Hemp Essentials — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Full Spectrum CBD 725 mg by Hemp Essentials
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: hemp extract at 725 mg per serving. Hemp extract is derived from the cannabis plant and contains compounds including cannabinoids and other plant constituents.
The liquid form also includes organic hemp seed oil as an inactive ingredient for consistency and delivery.
Does it work?
Couldn't assess
The evidence for hemp extract is still being built. We don't have reliable data on how well it works for constipation, eczema (atopic dermatitis), or high cholesterol — the conditions listed here.
That doesn't mean it won't help, just that the studies aren't yet strong enough to make a clear claim. If you're considering this for a specific condition, talk it over with your doctor or pharmacist about what the current research actually shows.
How safe is it?
Well-documented data
Hemp seed foods are generally well tolerated in normal amounts. This product is a concentrated extract, though, and concentrated hemp extracts and supplements are less studied than food sources — so caution is warranted.
Most people taking hemp products experience no problems, but rare cases of serious reactions have been reported, including allergic reactions (hives, swelling, shortness of breath) and very rarely anaphylaxis. There's also one case report of elevated liver enzymes and hepatitis in a young child given high-dose hemp extract.
We don't have enough safety data on this product in pregnancy or breastfeeding to know whether it's appropriate — talk with your doctor or pharmacist for personalized advice.
Meds to double-check
Moderate interaction found
Check before taking if you're on estrogen therapy or hormone-based birth control (hemp may reduce their effect). Also flag any blood thinners or antiplatelet drugs (aspirin, warfarin), ACE inhibitors or other blood pressure medications, and any drug your liver breaks down through CYP1A2 or CYP3A4 — a large group that includes some statins, antihistamines, and cancer medications.
Your pharmacist or doctor can look up your specific drugs.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Hemp Essentials Full Spectrum CBD 725 mg is a concentrated hemp extract — different from foods containing hemp seed — and carries several potential medication interactions you'll want to check before starting. If you take estrogen therapy, blood thinners, blood pressure medications, or drugs metabolized by your liver's CYP enzymes, this one needs a conversation with your own doctor or pharmacist.
They can review your exact medications and help you decide whether it's right for you.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Full Spectrum CBD 725 mg, straight from the product label.
| Brand | Hemp Essentials |
|---|---|
| Net contents | 0.5 fl. Oz.; 15 mL |
| Market status | On market |
| Date entered into DSLD | Jun 24, 2020 |
| DSLD ID | 228514 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Full Spectrum CBD 725 mg by Hemp Essentials, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Hemp extract | 24 mg | -- |
Other ingredients: 100% organic Hemp seed Oil
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement
Disclaimer: These statements have not been evaluated by the food and drug administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Precautions
Caution: Not intended for use under the age of 18.
Do not take if you are pregnant or breastfeeding. Consult your physician before use if you have a medical condition or are taking any medication.
Storage
In order to preserve freshness, store away from heat, light, and humidity.
Suggested/Recommended/Usage/Directions
Suggested Use: 0.5 mL (10 drops) under the tongue for 60 seconds 1-2 times daily.
Formulation
Lab tested.
CO2 extracted. No additives. No pesticides.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Full Spectrum CBD 725 mg by Hemp Essentials label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Full Spectrum CBD 725 mg by Hemp Essentials
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size0.5 mL Dosage formLiquid Servings per container30 Amounts shown are per serving.
Hemp extract
Interacts with938 drugs
Hemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for...
Hemp extract monograph & interactionsOther (inactive) ingredients: 100% organic Hemp seed Oil. These complete the product’s ingredient list but are not active constituents.
Full Spectrum CBD 725 mg by Hemp Essentials Drug Interactions
HelloPharmacist Interaction Report
Hemp Essentials Full Spectrum CBD 725 mg may interact with several medication types through its hemp extract content.
The most serious documented interaction is with estrogen therapy (hormone replacement therapy or birth control pills): hemp may theoretically interfere with how your body processes these hormones, potentially reducing their effectiveness, though the exact mechanism isn't fully understood.
Read the full breakdown — every affected drug type, severity by severity
Hemp also has Minor interactions documented with blood thinners and antiplatelet drugs (like warfarin or aspirin), ACE inhibitors for high blood pressure, and certain other blood pressure medications. The concern with blood thinners is theoretical — animal studies suggest hemp seed might increase bleeding risk, but human studies at typical doses haven't shown this effect.
For blood pressure drugs, hemp seed protein in lab studies showed ACE inhibitor-like activity, meaning it could add to your medication's effect and lower blood pressure too much.
Additionally, hemp may speed up how your liver breaks down certain medications processed through CYP1A2 and CYP3A4 enzymes (a large group that includes some statin cholesterol drugs, certain antihistamines, some cancer drugs, and others), potentially making them less effective. Altogether, these interactions span 939 individual medications.
Before you start this product, run your exact prescriptions through the interaction checker on this page.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Full Spectrum CBD 725 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Full Spectrum CBD 725 mg interact with 938 drugs. Click any drug to see the details.
1 of the 1 ingredient in Full Spectrum CBD 725 mg interact with drugs. Each result below shows which ingredient is responsible. Hemp extract
Ado-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Full Spectrum CBD 725 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Extract + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with Full Spectrum CBD 725 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Hemp Extract + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Full Spectrum CBD 725 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Extract + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Full Spectrum CBD 725 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Extract + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Full Spectrum CBD 725 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Extract + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Full Spectrum CBD 725 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Hemp Extract + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Full Spectrum CBD 725 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Extract + Acalabrutinib interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Full Spectrum CBD 725 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractAntihypertensive Drugs Minor
Interaction Summary
Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
Read the full Hemp Extract + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Full Spectrum CBD 725 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Hemp Extract + Acenocoumarol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Full Spectrum CBD 725 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Extract + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Full Spectrum CBD 725 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Full Spectrum CBD 725 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Hemp Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Full Spectrum CBD 725 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Full Spectrum CBD 725 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Extract + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Full Spectrum CBD 725 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Full Spectrum CBD 725 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Full Spectrum CBD 725 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Full Spectrum CBD 725 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Full Spectrum CBD 725 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Full Spectrum CBD 725 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Full Spectrum CBD 725 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Full Spectrum CBD 725 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Full Spectrum CBD 725 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Extract + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Full Spectrum CBD 725 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Full Spectrum CBD 725 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Full Spectrum CBD 725 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Full Spectrum CBD 725 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Full Spectrum CBD 725 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Full Spectrum CBD 725 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Full Spectrum CBD 725 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Full Spectrum CBD 725 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Hemp extract
Estrogens
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
In an ovariectomized animal model, a diet containing hemp seed 1%, 2%, or 10% resulted in normalized plasma levels of 17-beta-estradiol. The mechanism of action for this effect is unclear.
Ace Inhibitors (Aceis)
Theoretically, consuming hemp seed protein isolate with ACE inhibitors might have additive effects and increase the risk of hypotension.
Hemp seed protein hydrolysate has shown ACE inhibitor-like effects in a hypertensive animal model. However, hempseed oil consumption does not seem to reduce blood pressure in humans. Until more is known, monitor blood pressure and potassium levels.
Anticoagulant/Antiplatelet Drugs
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
In animal research, hemp seed at 5% of the diet inhibits platelet aggregation in vitro. However, in human research, taking hemp seed oil 2 grams daily for 12 weeks does not inhibit the aggregation of platelets in vitro.
Antihypertensive Drugs
Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
In a hypertensive animal model, hemp seed protein hydrolysate reduced systolic blood pressure by a mechanism possibly involving the inhibition of renin and angiotensin converting enzyme (ACE) activities. However, there was no effect of hemp seed protein on blood pressure in normotensive animals. Furthermore, hempseed oil consumption does not seem to reduce blood pressure in humans.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that hemp induces CYP1A2 enzymes.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that hemp induces CYP3A4 enzymes.
Brand information
Manufacturer and brand details for Full Spectrum CBD 725 mg, from the product label.
Hemp Essentials
See all Hemp Essentials products- Name
- O Essentials
- City
- Crestwood
- State
- KY
- ZipCode
- 40014
- Web Address
- HempEssentials.com
Full Spectrum CBD 725 mg by Hemp Essentials: Common Questions
Does Full Spectrum CBD 725 mg by Hemp Essentials interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does hemp extract contain THC or get me high?
What should I do if I'm on birth control?
Are there any allergic reactions I should watch for?
Is this safe in pregnancy?
Can I take this if I'm on blood pressure medicine?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Full Spectrum CBD 725 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Full Spectrum CBD 725 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Full Spectrum CBD 725 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 12 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Hemp 12 references
- Kaul N, Kreml R, Austria JA, et al. A comparison of fish oil, flaxseed oil and hempseed oil supplementation on selected parameters of cardiovascular health in healthy volunteers. J Am Coll Nutr 2008;27:51-8. PubMed
- Saberivand A, Karimi I, Becker LA, et al. The effects of Cannabis sativa L. seed (hempseed) in the ovariectomized rat model of menopause. Methods Find Exp Clin Pharmacol. 2010;32(7):467-73. PubMed
- Girgih AT, Alashi A, He R, Malomo S, Aluko RE. Preventive and treatment effects of a hemp seed (Cannabis sativa L.) meal protein hydrolysate against high blood pressure in spontaneously hypertensive rats. Eur J Nutr. 2014;53(5):1237-46. PubMed
- Richard MN, Ganguly R, Steigerwald SN, Al-Khalifa A, Pierce GN. Dietary hempseed reduces platelet aggregation. J Thromb Haemost. 2007;5(2):424-5. PubMed
- Stadtmauer G, Beyer K, Bardina L, Sicherer SH. Anaphylaxis to ingestion of hempseed (Cannabis sativa). J Allergy Clin Immunol. 2003;112(1):216-7. PubMed
- Del Bo' C, Deon V, Abello F, et al. Eight-week hempseed oil intervention improves the fatty acid composition of erythrocyte phospholipids and the omega-3 index, but does not affect the lipid profile in children and adolescents with primary hyperlipidemia. PubMed
- Alkhammash S, Tsui H, Thomson DMP. Cannabis and hemp seed allergy. J Allergy Clin Immunol Pract. 2019;7(7):2429-2430.e1. PubMed
- Stokes JR, Hartel R, Ford LB, Casale TB. Cannabis (hemp) positive skin tests and respiratory symptoms. Ann Allergy Asthma Immunol. 2000;85(3):238-40. PubMed
- Déléaval M, Burri H, Bakelants E. Harmless herbs? A case report of acquired long QT syndrome and torsades de pointes in a patient taking herbal supplements. HeartRhythm Case Rep 2022;8(5):309-12. PubMed
- Singh M, Sehgal M, Yacoub M, et al. Severe liver dysfunction in a toddler receiving nonprescription phytocannabinoid. J Am Pharm Assoc (2003) 2022;62(4):1438-1440. PubMed
- Clark E, Nilsson U, Samaran Q, Raison-Peyron N. Allergic contact dermatitis from Cannabis sativa (hemp) seed oil. Contact Dermatitis 2022;87(3):292-293.
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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