Hemp Softgels 300 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Hemp Softgels 300 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Hemp Softgels 300 mg is a dietary supplement by Tommy Chong's Hemp with 2 active ingredients. Its ingredients are commonly taken for plant-based protein source, heart health support, skin and hair health.Based on those ingredients, 938 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Hemp extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Hemp Softgels 300 mg by Tommy Chong's Hemp
Ask about any prescription or over-the-counter medication and we check it for interactions with Hemp Softgels 300 mg by Tommy Chong's Hemp — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Hemp Softgels 300 mg by Tommy Chong's Hemp
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This softgel contains 2 active ingredients: hemp extract (the herbal ingredient) and medium chain triglyceride oil (a carrier oil that helps deliver it). The softgel capsule itself is made from gelatin, glycerin, and purified water.
Does it work?
Couldn't assess
The evidence we hold for hemp extract doesn't establish that it works for the uses listed — constipation, eczema, and familial high cholesterol (a genetic condition affecting cholesterol levels) are all rated as having insufficient reliable evidence. That doesn't mean it doesn't help; it means the research isn't there yet to say one way or another.
How safe is it?
Well-documented data
Hemp seed foods are generally well tolerated at normal amounts, but concentrated extracts like this supplement are less studied, so caution is advised. In larger doses or extract form, rare serious effects have been reported: allergic reactions (hives, facial swelling, trouble breathing, anaphylaxis), heart rhythm problems, and in one case, liver inflammation in a young child given very high doses.
Allergy to hemp seed is uncommon but does occur. Because concentrated extracts are not well studied, talk with your doctor or pharmacist about whether this is right for you.
Meds to double-check
Moderate interaction found
Before you start, check with your pharmacist if you take estrogen or hormone therapy (Moderate severity), blood thinners or antiplatelet drugs, blood pressure medications (especially ACE inhibitors), or any drugs metabolized by your liver's CYP1A2 or CYP3A4 enzymes. These are the main medication types documented to interact with hemp extract.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product might appeal to someone looking for hemp in softgel form, but the evidence for what it treats isn't solid yet. If you take estrogen therapy, blood thinners, blood pressure medication, or drugs your liver breaks down, you need to check with your pharmacist first — hemp can interfere with all of these.
The fact that concentrated hemp extracts are less studied than whole hemp foods is worth keeping in mind.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Hemp Softgels 300 mg, straight from the product label.
| Brand | Tommy Chong's Hemp |
|---|---|
| Barcode (UPC) | 686091747620 |
| Net contents | 30 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Aug 22, 2024 |
| DSLD ID | 315805 |
| Product type | Botanical With Nutrients |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Hemp Softgels 300 mg by Tommy Chong's Hemp, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Medium Chain Triglyceride Oil | 490 mg | -- |
| Hemp extract | 25 mg | -- |
Other ingredients: purified Water, Gelatin, Glycerin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Directions: Take one (1) softgel daily, or as instructed by a healthcare provider.
Precautions
Warning: Seek the advice of a healthcare provider before using this product.
Keep out of reach of children.
FDA Disclaimer Statement
This product has not been evaluated by the Food and Drug Administration. It is not intended to cure, treat, diagnose, or prevent any disease.
The FDA does not recognize Hemp as a dietary supplement.
Seals/Symbols
GMP Good Manufacturing Practice Made in the USA Vegan Friendly
Formulation
Vegan Friendly
100% natural GMO free
100% natural GMO free
Full Spectrum Fast Acting
Formula
Hemp 10mg per serving
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Hemp Softgels 300 mg by Tommy Chong's Hemp label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Hemp Softgels 300 mg by Tommy Chong's Hemp
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Medium Chain Triglyceride Oil
Hemp extract
Interacts with938 drugs
Hemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for...
Hemp extract monograph & interactionsOther (inactive) ingredients: Purified Water, Gelatin, Glycerin. These complete the product’s ingredient list but are not active constituents.
Hemp Softgels 300 mg by Tommy Chong's Hemp Drug Interactions
HelloPharmacist Interaction Report
Tommy Chong's Hemp Softgels 300 mg contains hemp extract, which interacts with several medication types.
The most serious documented interaction is with estrogens (hormone therapy). Hemp may interfere with how your body handles estrogen due to its own estrogenic effects — animal research shows it can normalize estrogen levels, though we don't yet know exactly how this works in people taking hormone medications.
Read the full breakdown — every affected drug type, severity by severity
Minor interactions are documented with blood thinners and antiplatelet drugs (like warfarin or aspirin), blood pressure medications including ACE inhibitors, and two groups of drugs your liver breaks down: CYP1A2 and CYP3A4 substrates. For blood thinners, human data didn't show an effect on platelet clotting when people took hemp seed oil, but animal work suggests a theoretical risk — worth checking with your pharmacist.
For blood pressure drugs and liver-metabolized medications, hemp may reduce how well they work by speeding up their breakdown in your body.
We could not check Medium Chain Triglyceride Oil — no interaction data is on file for it. Altogether, these interactions span 927 individual medications.
Use the medication checker on this page to look up your exact prescriptions before starting.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Hemp Softgels 300 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Hemp Softgels 300 mg interact with 938 drugs. Click any drug to see the details.
1 of the 2 ingredients in Hemp Softgels 300 mg interact with drugs. Each result below shows which ingredient is responsible. Hemp extract
Bazedoxifene Acetate, Conjugated EstrogensDuavee
How Bazedoxifene Acetate, Conjugated Estrogens interacts with Hemp Softgels 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Hemp Extract + Bazedoxifene Acetate, Conjugated Estrogens interactionConjugated EstrogensCenestin, Enjuvia, Premarin, Premarin Vaginal Cream
How Conjugated Estrogens interacts with Hemp Softgels 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Extract + Conjugated Estrogens interactionConjugated Estrogens, Medroxyprogesterone AcetatePremplus, Prempro
How Conjugated Estrogens, Medroxyprogesterone Acetate interacts with Hemp Softgels 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Hemp Extract + Conjugated Estrogens, Medroxyprogesterone Acetate interactionConjugated Estrogens, MeprobamatePMB 200, PMB 400
How Conjugated Estrogens, Meprobamate interacts with Hemp Softgels 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Hemp Extract + Conjugated Estrogens, Meprobamate interactionConjugated Estrogens, MethyltestosteronePremarin with Methyltestosterone
How Conjugated Estrogens, Methyltestosterone interacts with Hemp Softgels 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Extract + Conjugated Estrogens, Methyltestosterone interactionCyproterone Acetate, Ethinyl EstradiolDiane-35, Dianette
How Cyproterone Acetate, Ethinyl Estradiol interacts with Hemp Softgels 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractEstrogens, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Hemp Extract + Cyproterone Acetate, Ethinyl Estradiol interactionDesogestrel, Ethinyl EstradiolDesogen, Marvelon, Marvelon 21, Marvelon 28, Mircette, Ortho-Cept +2 more
How Desogestrel, Ethinyl Estradiol interacts with Hemp Softgels 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Extract + Desogestrel, Ethinyl Estradiol interactionDrospirenone, EstetrolNextstellis
How Drospirenone, Estetrol interacts with Hemp Softgels 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Extract + Drospirenone, Estetrol interactionDrospirenone, Ethinyl EstradiolAngeliq, Gianvi, Yasmin
How Drospirenone, Ethinyl Estradiol interacts with Hemp Softgels 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Extract + Drospirenone, Ethinyl Estradiol interactionEsterified EstrogensEstratab, Menest
How Esterified Estrogens interacts with Hemp Softgels 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Hemp Extract + Esterified Estrogens interactionEsterified Estrogens, MethyltestosteroneEstratest
How Esterified Estrogens, Methyltestosterone interacts with Hemp Softgels 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Extract + Esterified Estrogens, Methyltestosterone interactionEstradiolDivigel, Elestrin, Estrace, Estraderm, Estring, Evamist +6 more
How Estradiol interacts with Hemp Softgels 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractEstrogens, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Hemp Extract + Estradiol interactionEstradiol, MedroxyprogesteroneDivitren
How Estradiol, Medroxyprogesterone interacts with Hemp Softgels 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Extract + Estradiol, Medroxyprogesterone interactionEstradiol, Norethindrone AcetateActivella
How Estradiol, Norethindrone Acetate interacts with Hemp Softgels 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Extract + Estradiol, Norethindrone Acetate interactionEstradiol, NorgestimateOrtho-Prefest
How Estradiol, Norgestimate interacts with Hemp Softgels 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractEstrogens, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Hemp Extract + Estradiol, Norgestimate interactionEstradiol, ProgesteroneBijuvanda
How Estradiol, Progesterone interacts with Hemp Softgels 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Extract + Estradiol, Progesterone interactionEstrogenEstrogen
How Estrogen interacts with Hemp Softgels 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Hemp Extract + Estrogen interactionEstroneOrtho-Est
How Estrone interacts with Hemp Softgels 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractEstrogens Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Hemp Extract + Estrone interactionEstropipateOgen, Ortho EST
How Estropipate interacts with Hemp Softgels 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractEstrogens Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Hemp Extract + Estropipate interactionEthiny Estradiol, LevonorgestrelLogynon, Microgynon 30 ED
How Ethiny Estradiol, Levonorgestrel interacts with Hemp Softgels 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Hemp Extract + Ethiny Estradiol, Levonorgestrel interactionEthinyl EstradiolEstinyl
How Ethinyl Estradiol interacts with Hemp Softgels 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Extract + Ethinyl Estradiol interactionEthinyl Estradiol, DesogestrelApri, Cesia, Cyclessa, Gedarel, Kariva, Linessa +4 more
How Ethinyl Estradiol, Desogestrel interacts with Hemp Softgels 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Extract + Ethinyl Estradiol, Desogestrel interactionEthinyl Estradiol, DrospirenoneYaz
How Ethinyl Estradiol, Drospirenone interacts with Hemp Softgels 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractEstrogens, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Hemp Extract + Ethinyl Estradiol, Drospirenone interactionEthinyl Estradiol, Ethynodiol DiacetateDemulen 1/35, Demulen 1/50, Demulen Compack, Kelnor 1/35, Zovia, Zovia 1/35 +1 more
How Ethinyl Estradiol, Ethynodiol Diacetate interacts with Hemp Softgels 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Extract + Ethinyl Estradiol, Ethynodiol Diacetate interactionEthinyl Estradiol, LevonorgestrelAlesse, Alesse 21, Alesse 28, Aviane, Enpresse, Jolessa +18 more
How Ethinyl Estradiol, Levonorgestrel interacts with Hemp Softgels 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Extract + Ethinyl Estradiol, Levonorgestrel interactionEthinyl Estradiol, NorethindroneAranelle, Brevicon, Brevicon .5/35 21 day, Brevicon .5/35 28 day, Brevicon 1/35 21 day, Brevicon 1/35 28 day +50 more
How Ethinyl Estradiol, Norethindrone interacts with Hemp Softgels 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Extract + Ethinyl Estradiol, Norethindrone interactionEthinyl Estradiol, Norethindrone, Ferrous FumarateEstrostep Fe, Femcon FE, Junel Fe 1.5/30, Loestrin Fe, Loestrin Fe 1.5/30, Loestrin Fe 1/20 +3 more
How Ethinyl Estradiol, Norethindrone, Ferrous Fumarate interacts with Hemp Softgels 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Extract + Ethinyl Estradiol, Norethindrone, Ferrous Fumarate interactionEthinyl Estradiol, NorgestimateCilest, Mononessa, Ortho Tri-Cyclen 28, Ortho Tri-Cyclen Lo, Ortho Tri-Cylcen, Ortho-Cyclen +5 more
How Ethinyl Estradiol, Norgestimate interacts with Hemp Softgels 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Extract + Ethinyl Estradiol, Norgestimate interactionEthinyl Estradiol, NorgestrelCryselle, Lo/Ovral, Low-Ogestrel, Ogestrel 0.5/50, Ovral
How Ethinyl Estradiol, Norgestrel interacts with Hemp Softgels 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Extract + Ethinyl Estradiol, Norgestrel interactionEthinyl Estradiol, LevonogestrelLybrel
How Ethinyl Estradiol, Levonogestrel interacts with Hemp Softgels 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Hemp Extract + Ethinyl Estradiol, Levonogestrel interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Hemp Softgels 300 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Hemp extract
Estrogens
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
In an ovariectomized animal model, a diet containing hemp seed 1%, 2%, or 10% resulted in normalized plasma levels of 17-beta-estradiol. The mechanism of action for this effect is unclear.
Ace Inhibitors (Aceis)
Theoretically, consuming hemp seed protein isolate with ACE inhibitors might have additive effects and increase the risk of hypotension.
Hemp seed protein hydrolysate has shown ACE inhibitor-like effects in a hypertensive animal model. However, hempseed oil consumption does not seem to reduce blood pressure in humans. Until more is known, monitor blood pressure and potassium levels.
Anticoagulant/Antiplatelet Drugs
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
In animal research, hemp seed at 5% of the diet inhibits platelet aggregation in vitro. However, in human research, taking hemp seed oil 2 grams daily for 12 weeks does not inhibit the aggregation of platelets in vitro.
Antihypertensive Drugs
Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
In a hypertensive animal model, hemp seed protein hydrolysate reduced systolic blood pressure by a mechanism possibly involving the inhibition of renin and angiotensin converting enzyme (ACE) activities. However, there was no effect of hemp seed protein on blood pressure in normotensive animals. Furthermore, hempseed oil consumption does not seem to reduce blood pressure in humans.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that hemp induces CYP1A2 enzymes.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that hemp induces CYP3A4 enzymes.
Brand information
Manufacturer and brand details for Hemp Softgels 300 mg, from the product label.
Tommy Chong's Hemp
See all Tommy Chong's Hemp products- Name
- Tommy Chong's Hemp
- Street Address
- 2180 E 4500 S #180
- City
- Holladay
- State
- UT
- ZipCode
- 84117
- Phone Number
- 833-667-3223
Hemp Softgels 300 mg by Tommy Chong's Hemp: Common Questions
Does Hemp Softgels 300 mg by Tommy Chong's Hemp interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is hemp extract the same as CBD or marijuana?
Can I take this if I'm pregnant or breastfeeding?
What are the side effects I might notice?
Will this help my constipation or eczema?
Why does this product interact with so many medications?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Hemp Softgels 300 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Hemp Softgels 300 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Hemp Softgels 300 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 12 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Hemp 12 references
- Kaul N, Kreml R, Austria JA, et al. A comparison of fish oil, flaxseed oil and hempseed oil supplementation on selected parameters of cardiovascular health in healthy volunteers. J Am Coll Nutr 2008;27:51-8. PubMed
- Saberivand A, Karimi I, Becker LA, et al. The effects of Cannabis sativa L. seed (hempseed) in the ovariectomized rat model of menopause. Methods Find Exp Clin Pharmacol. 2010;32(7):467-73. PubMed
- Girgih AT, Alashi A, He R, Malomo S, Aluko RE. Preventive and treatment effects of a hemp seed (Cannabis sativa L.) meal protein hydrolysate against high blood pressure in spontaneously hypertensive rats. Eur J Nutr. 2014;53(5):1237-46. PubMed
- Richard MN, Ganguly R, Steigerwald SN, Al-Khalifa A, Pierce GN. Dietary hempseed reduces platelet aggregation. J Thromb Haemost. 2007;5(2):424-5. PubMed
- Stadtmauer G, Beyer K, Bardina L, Sicherer SH. Anaphylaxis to ingestion of hempseed (Cannabis sativa). J Allergy Clin Immunol. 2003;112(1):216-7. PubMed
- Del Bo' C, Deon V, Abello F, et al. Eight-week hempseed oil intervention improves the fatty acid composition of erythrocyte phospholipids and the omega-3 index, but does not affect the lipid profile in children and adolescents with primary hyperlipidemia. PubMed
- Alkhammash S, Tsui H, Thomson DMP. Cannabis and hemp seed allergy. J Allergy Clin Immunol Pract. 2019;7(7):2429-2430.e1. PubMed
- Stokes JR, Hartel R, Ford LB, Casale TB. Cannabis (hemp) positive skin tests and respiratory symptoms. Ann Allergy Asthma Immunol. 2000;85(3):238-40. PubMed
- Déléaval M, Burri H, Bakelants E. Harmless herbs? A case report of acquired long QT syndrome and torsades de pointes in a patient taking herbal supplements. HeartRhythm Case Rep 2022;8(5):309-12. PubMed
- Singh M, Sehgal M, Yacoub M, et al. Severe liver dysfunction in a toddler receiving nonprescription phytocannabinoid. J Am Pharm Assoc (2003) 2022;62(4):1438-1440. PubMed
- Clark E, Nilsson U, Samaran Q, Raison-Peyron N. Allergic contact dermatitis from Cannabis sativa (hemp) seed oil. Contact Dermatitis 2022;87(3):292-293.
- Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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