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Dietary supplement

Glutamine Alkaline Ingredients & Drug Interactions

by BPI Sports

Glutamine Alkaline label
See full label image
Powder Category: Amino Acid/protein
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Glutamine Alkaline against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Glutamine Alkaline is a dietary supplement by BPI Sports with 1 active ingredient. Its ingredients are commonly taken for muscle recovery and sports performance, gut health and 'leaky gut', recovery from severe illness or injury.Based on those ingredients, 50 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Glutamine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Glutamine Alkaline by BPI Sports

Ask about any prescription or over-the-counter medication and we check it for interactions with Glutamine Alkaline by BPI Sports — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Glutamine Alkaline by BPI Sports

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: glutamine, an amino acid your body uses for immune function, gut health, and muscle recovery after stress or illness. The remaining ingredients — pH-Sorb buffering technology, taurine, silica, Resolver, acesulfame-K, and sucralose — are inactive excipients (fillers and flavorings that stabilize and sweeten the powder).

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: muscle recovery and anabolic support.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Postoperative recovery, Wound healing, muscle protein synthesis, lean mass gain.
  • The strongest evidence on file: Glutamine is rated "Possibly Effective" for Postoperative recovery (Natural Medicines).
  • Also on file: Glutamine is rated "Possibly Ineffective" for Athletic performance.
  • Also on file: Glutamine is rated "Insufficient Reliable Evidence To Rate" for Wound healing, Exercise-induced muscle damage.

Glutamine is rated Effective for sickle cell disease. It's rated Possibly Effective for HIV/AIDS-related wasting, postoperative recovery, and critical illness from trauma.

The evidence supporting those uses exists but isn't as robust as the sickle cell data.

The evidence, ingredient by ingredient Glutamine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Glutamine is generally well tolerated when taken by mouth. The most common side effects in studies were belching, bloating, constipation, diarrhea, flatulence, nausea, vomiting, headache, and gastrointestinal pain — most mild and dose-dependent.

High doses (10–30 grams daily) used in clinical trials for sickle cell disease produced more GI upset. Dizziness and headache have been reported, and there are two cases of mania or hypomania in people with bipolar disorder taking up to 4 grams daily, though glutamine is not established as a cause.

If you have kidney or liver disease, use only under a doctor's supervision. The safety data in pregnancy is limited but rated Likely Safe; however, there isn't enough reliable safety information during breastfeeding, so check with your doctor or pharmacist before taking a supplement dose while nursing.

Side effects, ingredient by ingredient Glutamine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Glutamine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: seizure medications.
  • For scale: 50 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Anticonvulsant medications (seizure drugs) are the main concern with glutamine — there's a theoretical Moderate-severity interaction. Glutamine is metabolized to glutamate, which might reduce how well seizure medications work, although this hasn't been observed in patients yet.

Check your exact anticonvulsant with your doctor or pharmacist before taking this product.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Glutamine Alkaline may help if you have sickle cell disease or need support after surgery or critical illness, though the evidence for those last two is still developing. If you take an anticonvulsant (seizure medication), check with your doctor or pharmacist first — there's a theoretical interaction we need to rule out for your specific drug.

Anyone with kidney or liver problems should also get clearance from their own healthcare provider before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Glutamine Alkaline, straight from the product label.

Brand BPI Sports
Barcode (UPC) 851780005965
Net contents 3.53 oz.; 100 Gram(s)
Market status On market
Date entered into DSLD Mar 25, 2015
DSLD ID 43264
Product type Amino Acid/protein
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Glutamine Alkaline by BPI Sports, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Scoop(s)
Maximum serving Sizes:
1 Scoop(s)
Servings per container
40
UPC/BARCODE
851780005965
IngredientAmount% DV
Glutamine1.5 Gram(s)--

Other ingredients: pH-Sorb(TM) Buffering Technology, Taurine, Silica, Resolver, Acesulfame-K, Sucralose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

40 SERVINGS

Warnings: Not intended for use by persons under age 18.

Do not exceed recommended dose.

Get the consent of a licensed physician before using this product, especially if you are taking medication, have a medical condition, you are pregnant, nursing or thinking about becoming pregnant.

KEEP THIS PRODUCT AND ALL SUPPLEMENTS OUT OF THE REACH OF CHILDREN.

General Statements

Please read entire label before use.

{chart} These POWERFUL Stacks when used together are designed to help promote the ultimate Anabolic physique.* WORKOUT DAYS NON-WORKOUT DAYS STACKING PROTOCOL PRE-WORKOUT POST-WORKOUT MORNING AFTERNOON BETA-ALKALINE(TM) {scoop}x1 20-30 MIN PRIOR {scoop}x1 CREATINE-ALKALINE(TM) {capsule}x2 PRIOR {scoop}x2 IMMEDIATELY AFTER {capsule}x2 GLUTA-ALKALINE(TM) {scoop}x1 {scoop}x1 {scoop}x1 LEUCINE AGMA (TM) {scoop}x1 {scoop}x1 {scoop}x1

Studies show that L-Glutamine plays a role in protein synthesis, and at the same time helps to promote an anabolic state by down-regulating catabolic activity. In fact, some important researchers are now suggesting that Glutamine might be the most important of all amino acids – as it provides a component in muscle metabolism and cellular support not shared by any other single amino acid.

References select isolated constituent parts, as it relates to analytical characterization of the same. When combined with a proper exercise and nutrition regimen. Statements based on early-stage independent 3rd party in vivo and / or in vitro model scientific research data findings for individual ingredients.

pH BALANCED MUSCLE RECOVERY

MAY EXPERIENCE: Increased Muscle* Increased Recovery* Increased Endurance*

Natural & Artificial Flavors

-RECOVERY* - ENDURANCE* - MUSCLE*

Suggested/Recommended/Usage/Directions

Suggested Use: Take one (1) serving (1 scoop) with approximately 6 ounces of water or juice, or as directed by a qualified healthcare practitioner. Can be taken pre/intra/or post workout. On non-training days, take one (1) serving (1 scoop) first thing in the morning on an empty stomach

General

Rev. 01-004-GPS003 03/14

Formula

Glutamine Alkaline(TM) is L-Glutamine and Trans-Alanyl-Glutamine.

In addition to L-Glutamine, CPS incorporates Trans-Alanyl-Glutamine, which may be more optimally taken up into the blood stream providing for greater muscle tissue levels of L-Glutamine. For enhanced nutrient uptake, the patent-pending pH Balanced Alkaline Buffering System pH-Sorb(TM) has been added, which is designed to directly influence the acidity level during metabolization, for optimal uptake and utilization.*

PRO LEVEL L-GLUTAMINE & TRANS-ALANYL-GLUTAMINE

FDA Disclaimer Statement

*THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT, CURE, OR PREVENT ANY DISEASE.

Seals/Symbols

LABORATORY CERTIFIED Independent Third-Party

pH SORB(TM) BUFFERING TECHNOLOGY PATENT PENDING

FDA Statement of Identity

DIETARY SUPPLEMENT

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Glutamine Alkaline by BPI Sports label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Glutamine Alkaline label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Glutamine Alkaline by BPI Sports

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Scoop(s) Dosage formPowder Servings per container40 Amounts shown are per serving.

Glutamine

Interacts with
50 drugs
1.5 Gram(s) per serving Form: L-Glutamine, Trans-Alanyl-Glutamine

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...

Glutamine monograph & interactions

Other (inactive) ingredients: PH-Sorb(TM) Buffering Technology, Taurine, Silica, Resolver, Acesulfame-K, Sucralose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Glutamine Alkaline by BPI Sports Drug Interactions

Want to check YOUR meds against Glutamine Alkaline?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
50Drugs
50 Moderate

Ingredients driving the most interactions

Glutamine 50

Individual Drug Interactions

The ingredients in Glutamine Alkaline interact with 50 drugs. Click any drug to see the details.

1 of the 1 ingredient in Glutamine Alkaline interact with drugs. Each result below shows which ingredient is responsible. Glutamine

Each ingredient & the kinds of drugs it affects

For each ingredient in Glutamine Alkaline with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Glutamine1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
Glutamine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Glutamine Alkaline, from the product label.

BPI Sports

See all BPI Sports products
Web Address
www.bpisports.net
Pharmacist Counseling Corner

Glutamine Alkaline by BPI Sports: Common Questions

Does Glutamine Alkaline by BPI Sports interact with any medications?
Yes. Based on its ingredients, Glutamine Alkaline has a known interaction with 50 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Glutamine Alkaline contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is glutamine safe to take while pregnant?
Yes — glutamine is rated Likely Safe in pregnancy based on available data. If you have any concerns about your specific situation, talk with your doctor.
Can I take this while breastfeeding?
There isn't enough reliable safety information to know either way. Check with your doctor or pharmacist for personalized advice before taking a supplement dose while nursing.
What's the most common side effect?
Gastrointestinal symptoms — bloating, constipation, diarrhea, nausea, and belching — are the most frequently reported, especially at higher doses. These tend to be mild and improve with dose reduction.
What is glutamine used for in this product?
Glutamine is an amino acid that supports immune function, gut health, and muscle recovery after stress, surgery, or critical illness. It's rated Effective for sickle cell disease and Possibly Effective for HIV/AIDS-related wasting and postoperative recovery.
Does this product contain any fillers?
Yes — the inactive ingredients include pH-Sorb buffering technology, taurine, silica, Resolver, acesulfame-K, and sucralose, which stabilize the powder and improve taste. The only active ingredient is glutamine.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Glutamine Alkaline is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Glutamine Alkaline label
Go deeper

The Full Monographs Behind Glutamine Alkaline’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glutamine

Interacts with 50 drugs

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle cell disease complications, but for most...

Read the full Glutamine monograph →
Sources

Sources & How We Checked

Glutamine Alkaline's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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