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Dietary supplement

Glutamine Micronized Watermelon Ingredients & Drug Interactions

by Dymatize Nutrition

Powder Category: Amino Acid/protein
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Glutamine Micronized Watermelon is a dietary supplement by Dymatize Nutrition with 1 active ingredient. Its ingredients are commonly taken for muscle recovery and sports performance, gut health and 'leaky gut', recovery from severe illness or injury.Based on those ingredients, 50 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Glutamine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Glutamine Micronized Watermelon by Dymatize Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: L-glutamine, an amino acid (a building block of protein) that your body uses for immune function, muscle repair, and intestinal health. The watermelon flavor comes from natural and artificial flavoring, erythritol (a sugar alcohol), citric acid, malic acid, beet root powder, sucralose, and acesulfame potassium, which are inactive ingredients.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: muscle protein synthesis and recovery support.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Postoperative recovery, Wound healing, Critical illness (trauma), Sports nutrition — and 1 related terms.
  • The strongest evidence on file: Glutamine is rated "Possibly Effective" for Critical illness (trauma) (Natural Medicines).
  • Also on file: Glutamine is rated "Possibly Effective" for Postoperative recovery.
  • Also on file: Glutamine is rated "Possibly Ineffective" for Athletic performance.

L-glutamine is rated Effective for sickle cell disease. It's rated Possibly Effective for HIV/AIDS-related wasting, postoperative recovery, and critical illness from trauma.

The evidence behind those "possibly effective" ratings hasn't been fully established in the data we hold, so talk with your doctor about whether this product might help your specific situation.

The evidence, ingredient by ingredient Glutamine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Glutamine is generally well tolerated in healthy adults, but people with kidney or liver disease should take it only under medical supervision. The most common side effects are gastrointestinal — belching, bloating, constipation, diarrhea, flatulence, nausea, and vomiting.

Headache and musculoskeletal pain have also been reported. Dizziness occurred in one person at a high dose but resolved when the dose was lowered.

There isn't enough safety data to recommend supplemental glutamine during pregnancy or breastfeeding unless your doctor advises it. If you're pregnant or breastfeeding and considering this product, check with your doctor or pharmacist first.

Side effects, ingredient by ingredient Glutamine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Glutamine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: seizure medications.
  • For scale: 50 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start, check with your doctor or pharmacist if you take any anticonvulsant (seizure) medications — glutamine theoretically could interfere with how they work. The interaction hasn't been observed in people yet, but it's worth confirming your specific drugs are okay with this product.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Glutamine is a solid choice if you have sickle cell disease, or if your doctor recommends it for postoperative recovery or muscle wasting. If you take seizure medication, you'll need to clear this with your doctor or pharmacist first because of the potential for an interaction.

Either way, start a conversation with your own healthcare provider about whether it fits your needs.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Glutamine Micronized Watermelon, straight from the product label.

Brand Dymatize Nutrition
Barcode (UPC) 705016175031
Net contents 17.6 oz.; 1.1 lbs; 500 Gram(s)
Market status On market
Date entered into DSLD Jul 24, 2015
DSLD ID 47169
Product type Amino Acid/protein
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Glutamine Micronized Watermelon by Dymatize Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
9 Gram(s)
Maximum serving Sizes:
9 Gram(s)
Servings per container
56
UPC/BARCODE
705016175031
IngredientAmount% DV
L-Glutamine5 Gram(s)--

Other ingredients: Erythritol, Citric Acid, Natural and Artificial flavors, Mailc Acid, Beet root powder, Sucralose, Acesulfame Potassium

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

DIRECTIONS: As a dietary supplement, mix 2 scoops with 12 fl. oz. of water until dissolved.

Precautions

WARNING: Consult a physician before using this or any other product, if you are pregnant, lactating, or have any medical condition.

KEEP OUT OF REACH OF CHILDREN.

DYMATIZE(R) L-Glutamine, the free amino acid, is the single most abundant amino acid in skeletal muscle. L-Glutamine supports muscle protein synthesis in response to a strenuous workout as well as recovery processes. L-Glutamine is available in a variety of delicious flavors for a refreshing taste.

Seals/Symbols

Informed-Choice {check}.org Trusted by sport

General

REV001

Brand IP Statement(s)

YOUR AMBITION. OUR NUTRITION.(TM) DYMATIZE NUTRITION(R)

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

New Flavor

Supports Muscle Recovery Fast Absorption

NATURALLY & ARTIFICIALLY FLAVORED

FDA Statement of Identity

DIETARY SUPPLEMENT

See for yourself

Glutamine Micronized Watermelon by Dymatize Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Glutamine Micronized Watermelon by Dymatize Nutrition

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size9 Gram(s) Dosage formPowder Servings per container56 Amounts shown are per serving.

L-Glutamine

Interacts with
50 drugs
5 Gram(s) per serving

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...

L-Glutamine monograph & interactions

Other (inactive) ingredients: Erythritol, Citric Acid, Natural and Artificial flavors, Mailc Acid, Beet root powder, Sucralose, Acesulfame Potassium. These complete the product’s ingredient list but are not active constituents.

Interaction report

Glutamine Micronized Watermelon by Dymatize Nutrition Drug Interactions

Want to check YOUR meds against Glutamine Micronized Watermelon?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
50Drugs
50 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Glutamine Micronized Watermelon with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Glutamine1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Glutamine Micronized Watermelon, from the product label.

Dymatize Nutrition

See all Dymatize Nutrition products
Name
Dymatize Enterprises, LLC
City
Dallas
State
TX
ZipCode
75234
Phone Number
888-334-5326
Web Address
DYMATIZE.COM
Pharmacist Counseling Corner

Glutamine Micronized Watermelon by Dymatize Nutrition: Common Questions

Does Glutamine Micronized Watermelon by Dymatize Nutrition interact with any medications?
Yes. Based on its ingredients, Glutamine Micronized Watermelon has a known interaction with 50 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Glutamine Micronized Watermelon contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help me build muscle or recover from surgery?
Glutamine is rated Possibly Effective for postoperative recovery. The evidence isn't yet established in our data, so talk with your doctor about whether it's right for your situation and what dose would actually help.
What side effects should I watch for?
Most are digestive — bloating, gas, constipation, nausea, or diarrhea. Headache and dizziness have been reported, though dizziness usually goes away if you lower the dose. Stop and check with your pharmacist if anything feels off.
Is it safe if I have kidney or liver problems?
No — you'd need medical supervision to use it. Talk with your doctor or pharmacist before taking this product if you have either condition.
Can I take this while pregnant or breastfeeding?
There isn't enough data to know either way. If you're pregnant or breastfeeding and want to try glutamine, check with your doctor or pharmacist first — they can advise you based on your specific situation.
Does glutamine actually work for sickle cell disease?
Yes — it's rated Effective for sickle cell disease. For other uses like HIV-related wasting or postoperative recovery, the evidence is still developing. Your doctor can tell you if it's appropriate for what you need.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Glutamine Micronized Watermelon is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Glutamine Micronized Watermelon label
Go deeper

The Full Monographs Behind Glutamine Micronized Watermelon’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Glutamine Micronized Watermelon's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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