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Dietary supplement

Glutamine Powder Unflavored Ingredients & Drug Interactions

by MusclePharm MP Essentials

Glutamine Powder Unflavored label
See full label image
Powder Category: Amino Acid/protein
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Glutamine Powder Unflavored against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Glutamine Powder Unflavored is a dietary supplement by MusclePharm MP Essentials with 1 active ingredient. Its ingredients are commonly taken for muscle recovery and sports performance, gut health and 'leaky gut', recovery from severe illness or injury.Based on those ingredients, 50 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Glutamine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Glutamine Powder Unflavored by MusclePharm MP Essentials

Ask about any prescription or over-the-counter medication and we check it for interactions with Glutamine Powder Unflavored by MusclePharm MP Essentials — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Glutamine Powder Unflavored by MusclePharm MP Essentials

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This is a single-ingredient product: L-glutamine, a naturally occurring amino acid your body uses for muscle recovery, immune support, and gut health. There are no inactive ingredients or fillers — you're getting glutamine and nothing else in the powder.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Glutamine's overall clinical evidence instead.

Strong

Strong clinical evidence supports Glutamine for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Sickle cell disease — rated "Effective" (Natural Medicines).
  • On file: HIV/AIDS-related wasting — rated "Possibly Effective" (Natural Medicines).
  • On file: Critical illness (trauma) — rated "Possibly Effective" (Natural Medicines).
  • On file: Postoperative recovery — rated "Possibly Effective" (Natural Medicines).
  • On file: Pancreatitis — rated "Possibly Effective" (Natural Medicines).

The evidence we hold shows L-glutamine is effective for sickle cell disease. For HIV/AIDS-related wasting, postoperative recovery, and trauma-related critical illness, glutamine is rated possibly effective — meaning there's some promising research, but the case isn't completely settled yet.

The evidence, ingredient by ingredient Glutamine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Glutamine is generally well tolerated in healthy adults. The most common side effects from oral glutamine are mild and gastrointestinal: belching, bloating, constipation, flatulence, diarrhea, nausea, and vomiting — especially at higher doses (10–30 grams daily).

Dizziness and headache have also been reported. A few cases of mood changes (mania or hypomania) have appeared in people with bipolar disorder taking glutamine, so use caution if that applies to you.

If you have kidney or liver disease, use this only under medical supervision. The safety data in pregnancy is adequate — it's rated likely safe — but in lactation (breastfeeding), there isn't enough information, so talk with your clinician before taking supplement doses while nursing.

Side effects, ingredient by ingredient Glutamine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Glutamine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: seizure medications.
  • For scale: 50 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start, double-check anticonvulsant medications (seizure drugs) with your doctor or pharmacist. The interaction is theoretical but documented as Moderate severity.

Most other medication types show no documented interactions with the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Glutamine powder is worth considering if you're recovering from surgery or illness, or if you're managing sickle cell disease — evidence supports it for those uses. If you take anticonvulsant medications, check with your doctor or pharmacist first.

Otherwise, it's generally well tolerated, though GI side effects can happen at higher doses.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 16, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Glutamine Powder Unflavored, straight from the product label.

Brand MusclePharm MP Essentials
Net contents 600 Gram(s); 1.32 lb(s)
Market status On market
Date entered into DSLD Jun 16, 2022
DSLD ID 267285
Product type Amino Acid/protein
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Glutamine Powder Unflavored by MusclePharm MP Essentials, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
5 Gram(s)
Maximum serving Sizes:
5 Gram(s)
Servings per container
120
IngredientAmount% DV
L-Glutamine5 Gram(s)--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Storage

Storage: Store at room temperature. Exposure to heat, light or air can have negative effects related to product quality. Therefore keep out of direct light or heat. Keep sealed when not in use.

Precautions

Warning: This product is only intended for use by healthy adults over 18 years of age.

Consult your physician before using this product if you are taking any prescription or over the counter medications or supplements. Do not use this product if you are pregnant, expect to become pregnant or are nursing. Do not use this product if you are at risk or are being treated for any medical condition or if you are taking a MAO inhibitor.

Do not exceed recommended serving size or suggested use.

Keep out of reach of children.

Allergen Warning: This product was produced in facility that may also process ingredients containing milk, eggs, fish, shellfish, tree nuts, peanuts, wheat and soybeans.

Formula

5 grams of L-Glutamine per serving

Glutamine is important for your success MusclePharm Glutamine helps you rebuild and recover from even the toughest of workouts. Intense activity will deplete glutamine, an amino acid necessary for protein and muscle synthesis. Whether you follow an advanced training routine or are just starting one, MusclePharm Glutamine delivers a substantial, 5 gram serving of pure L-Glutamine to help support your goals.

Pure L-Glutamine powder

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

Made in a cGMP Registered Facility

Key features Helps build, repair and protect muscles Promotes recovery after intense exercise Supports gut and immune function

General Statements

Your personal best awaits.

Seals/Symbols

Banned substance tested Informed-Choice.org Trusted by sport

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: MusclePharm Glutamine has no taste or odor and can easily be mixed into water or your favorite beverage. For best results, consume one serving (one scoop) before or after training. Use as part of healthy diet and exercise program.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Glutamine Powder Unflavored by MusclePharm MP Essentials label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Glutamine Powder Unflavored label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Glutamine Powder Unflavored by MusclePharm MP Essentials

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size5 Gram(s) Dosage formPowder Servings per container120 Amounts shown are per serving.

L-Glutamine

Interacts with
50 drugs
5 Gram(s) per serving

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...

L-Glutamine monograph & interactions
Interaction report

Glutamine Powder Unflavored by MusclePharm MP Essentials Drug Interactions

Want to check YOUR meds against Glutamine Powder Unflavored?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
50Drugs
50 Moderate

Ingredients driving the most interactions

L-Glutamine 50

Individual Drug Interactions

The ingredients in Glutamine Powder Unflavored interact with 50 drugs. Click any drug to see the details.

1 of the 1 ingredient in Glutamine Powder Unflavored interact with drugs. Each result below shows which ingredient is responsible. L-Glutamine

Each ingredient & the kinds of drugs it affects

For each ingredient in Glutamine Powder Unflavored with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Glutamine1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
L-Glutamine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Glutamine Powder Unflavored, from the product label.

MusclePharm MP Essentials

See all MusclePharm MP Essentials products
Name
MusclePharm Corp.
Street Address
4400 Vanowen Street
City
Burbank
State
CA
ZipCode
91505
Pharmacist Counseling Corner

Glutamine Powder Unflavored by MusclePharm MP Essentials: Common Questions

Does Glutamine Powder Unflavored by MusclePharm MP Essentials interact with any medications?
Yes. Based on its ingredients, Glutamine Powder Unflavored has a known interaction with 50 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Glutamine Powder Unflavored contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is glutamine safe to take while pregnant?
Yes — the safety data rates glutamine as likely safe in pregnancy. But if you're breastfeeding, there isn't enough information yet, so talk with your doctor or pharmacist before taking supplement doses.
What are the most common side effects?
Gastrointestinal effects are most common: bloating, flatulence, diarrhea, constipation, nausea, and vomiting. These tend to happen at higher doses and are usually mild. Dizziness and headache have been reported too.
Does this powder have any fillers or ingredients besides glutamine?
No — it's unflavored glutamine powder with no inactive ingredients added. You're getting pure L-glutamine.
Will this help me recover from surgery?
The evidence rates glutamine as possibly effective for postoperative recovery, meaning research is promising but not definitive yet. Talk with your surgeon or doctor about whether it fits your recovery plan.
Can I take this if I have kidney or liver disease?
Only under medical supervision. Check with your doctor or pharmacist first, since your kidneys and liver are involved in processing glutamine.
I have bipolar disorder — is glutamine safe for me?
A small number of people with bipolar disorder taking glutamine have reported mood changes like mania or hypomania. Talk with your doctor or psychiatrist before starting, especially at higher doses.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Glutamine Powder Unflavored is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Glutamine Powder Unflavored label
Go deeper

The Full Monographs Behind Glutamine Powder Unflavored’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glutamine

Interacts with 50 drugs

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle cell disease complications, but for most...

Read the full Glutamine monograph →
Sources

Sources & How We Checked

Glutamine Powder Unflavored's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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