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Dietary supplement

Glutamine5000 Unflavored Ingredients & Drug Interactions

by Evlution Nutrition

Glutamine5000 Unflavored label
See full label image
Powder Category: Amino Acid/protein
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Glutamine5000 Unflavored against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Glutamine5000 Unflavored is a dietary supplement by Evlution Nutrition with 1 active ingredient. Its ingredients are commonly taken for muscle recovery and sports performance, gut health and 'leaky gut', recovery from severe illness or injury.Based on those ingredients, 50 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Glutamine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Glutamine5000 Unflavored by Evlution Nutrition

Ask about any prescription or over-the-counter medication and we check it for interactions with Glutamine5000 Unflavored by Evlution Nutrition — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Glutamine5000 Unflavored by Evlution Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 30, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Glutamine5000 Unflavored is a single-ingredient supplement: L-glutamine, an amino acid your body naturally produces. There are no other active ingredients or fillers in this product.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: support glutamine levels during and after exercise.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Postoperative recovery, muscle protein synthesis, nitrogen balance, post-exercise recovery.
  • The strongest evidence on file: Glutamine is rated "Possibly Effective" for Postoperative recovery (Natural Medicines).
  • Also on file: Glutamine is rated "Possibly Ineffective" for Athletic performance.
  • Also on file: Glutamine is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced muscle damage.

The data shows L-glutamine is effective for sickle cell disease. It's possibly effective for HIV/AIDS-related wasting, postoperative recovery, and critical illness from trauma.

For other uses not listed here, the evidence isn't established in the data we hold.

The evidence, ingredient by ingredient Glutamine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-glutamine is generally well tolerated when taken by mouth in most healthy adults. The most common side effects are gastrointestinal: belching, bloating, constipation, diarrhea, flatulence, gas, nausea, vomiting, and stomach pain.

Headache and musculoskeletal pain have also been reported. Dizziness has occurred in rare cases and resolved when the dose was lowered.

There are two reported cases of mania or hypomania in people with bipolar disorder taking glutamine; if you have bipolar disorder, talk with your doctor before starting. If you have kidney or liver disease, you should take this only under medical supervision.

The safety data for pregnancy is rated Likely Safe, but for breastfeeding there isn't enough reliable information — talk with your doctor or pharmacist before taking it while nursing.

Side effects, ingredient by ingredient Glutamine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Glutamine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: seizure medications.
  • For scale: 50 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take anticonvulsant (seizure) medications, talk with your doctor or pharmacist before starting this supplement — glutamine may theoretically reduce how well your drug works. That's the only drug interaction documented in the data we hold for this ingredient.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Glutamine5000 is useful if you have sickle cell disease or are recovering from surgery, trauma, or HIV-related wasting and your doctor has recommended it. If you take anticonvulsant (seizure) medications, check with your doctor or pharmacist before starting — that's the main interaction to watch.

It's generally well tolerated but can cause stomach upset, especially at higher doses.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 24, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Glutamine5000 Unflavored, straight from the product label.

Brand Evlution Nutrition
Barcode (UPC) 818901020313
Net contents 10.58 Ounce(s); 300 Gram(s)
Market status On market
Date entered into DSLD Jan 24, 2024
DSLD ID 302113
Product type Amino Acid/protein
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Glutamine5000 Unflavored by Evlution Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
5 Gram(s)
Maximum serving Sizes:
5 Gram(s)
Servings per container
60
UPC/BARCODE
818901020313
IngredientAmount% DV
L-Glutamine5000 mg--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Glutamine5000, when combined with proper exercise, is designed to support: Glutamine levels during prolonged exercise Post workout glutamine levels Nitrogen shuttling throughout the body

This product is made in the USA, has been distributed and manufactured by a (GMP) registered facility and contains ingredients of domestic and international origin.

Gluten free

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, mix 1 scoop of Glutamine5000 with your protein drink or 8oz of your beverage of choice post training.

Use anytime

Precautions

Warning: Not for use by those with pre-existing medical conditions; those taking any medications; those under the age of 18 or women who are contemplating pregnancy, pregnant or nursing.

Warning: Not for use by those with pre-existing medical conditions; those taking any medications; those under the age of 18 or women who are contemplating pregnancy, pregnant or nursing. Keep out of reach of children and pets.

Keep out of reach of children and pets.

Storage

Store in a dry place away from direct sunlight.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Instagram Facebook Twitter @EVLSports #EVL

Formula

Ultra pure L-glutamine 5g 5000 mg pure L-glutamine Plant based L-glutamine

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Made in the USA

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Glutamine5000 Unflavored by Evlution Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Glutamine5000 Unflavored label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Glutamine5000 Unflavored by Evlution Nutrition

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size5 Gram(s) Dosage formPowder Servings per container60 Amounts shown are per serving.

L-Glutamine

Interacts with
50 drugs
5000 mg per serving

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...

L-Glutamine monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

Glutamine5000 Unflavored by Evlution Nutrition Drug Interactions

Want to check YOUR meds against Glutamine5000 Unflavored?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
50Drugs
50 Moderate

Ingredients driving the most interactions

L-Glutamine 50

Individual Drug Interactions

The ingredients in Glutamine5000 Unflavored interact with 50 drugs. Click any drug to see the details.

1 of the 1 ingredient in Glutamine5000 Unflavored interact with drugs. Each result below shows which ingredient is responsible. L-Glutamine

Each ingredient & the kinds of drugs it affects

For each ingredient in Glutamine5000 Unflavored with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Glutamine1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
L-Glutamine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Glutamine5000 Unflavored, from the product label.

Evlution Nutrition

See all Evlution Nutrition products
Name
Evlution Nutrition
Street Address
1560 Sawgrass Corporate Parkway, 4th Floor
City
Sunrise
State
Florida
ZipCode
33323
Phone Number
1(855)385-2300
Web Address
Evlnutrition.com
Pharmacist Counseling Corner

Glutamine5000 Unflavored by Evlution Nutrition: Common Questions

Does Glutamine5000 Unflavored by Evlution Nutrition interact with any medications?
Yes. Based on its ingredients, Glutamine5000 Unflavored has a known interaction with 50 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Glutamine5000 Unflavored contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is L-glutamine and what does it do?
L-glutamine is an amino acid — a building block your body already makes. It plays roles in immune function, gut health, and muscle recovery. This supplement provides extra glutamine, which may be helpful if you're recovering from surgery, critical illness, or HIV-related wasting, or if you have sickle cell disease.
What are the most common side effects?
Stomach upset is the main one: belching, bloating, constipation, diarrhea, gas, nausea, vomiting, or stomach pain. Headache and muscle pain have also been reported. Most side effects tend to be mild, but high doses (10-30 grams daily) are more likely to cause GI trouble.
Is it safe to take while pregnant?
The safety data for pregnancy is rated Likely Safe. That said, if you're pregnant, talk with your doctor or pharmacist before starting any supplement to make sure it's right for your situation.
Can I take this if I'm breastfeeding?
There isn't enough reliable safety data on glutamine while breastfeeding. Talk with your doctor or pharmacist before taking supplement doses — they can advise you based on your own health and needs.
Is this product effective for muscle building or fitness?
The effectiveness data we hold covers sickle cell disease, HIV/AIDS wasting, postoperative recovery, and critical illness from trauma. We don't have evidence on file for muscle building or general fitness use.
What if I have kidney or liver disease?
If you have kidney or liver disease, you should use this supplement only under medical supervision. Talk with your doctor or pharmacist before starting to make sure it's safe for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Glutamine5000 Unflavored is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Glutamine5000 Unflavored label
Go deeper

The Full Monographs Behind Glutamine5000 Unflavored’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glutamine

Interacts with 50 drugs

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle cell disease complications, but for most...

Read the full Glutamine monograph →
Sources

Sources & How We Checked

Glutamine5000 Unflavored's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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