Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Glycation Protection Formula Ingredients & Drug Interactions

by Life Extension

Glycation Protection Formula label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Glycation Protection Formula against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Glycation Protection Formula is a dietary supplement by Life Extension with 3 active ingredients. Its ingredients are commonly taken for anti-aging and general wellness, exercise performance and muscle support, brain and cognitive health.Based on those ingredients, 296 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vitamin B6, L-Carnosine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Glycation Protection Formula by Life Extension

Ask about any prescription or over-the-counter medication and we check it for interactions with Glycation Protection Formula by Life Extension — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Glycation Protection Formula by Life Extension

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This formula contains 3 active ingredients. L-carnosine is a compound your body makes naturally; it's thought to protect cells from damage linked to aging and high blood sugar.

Benfotiamine is a fat-soluble form of B1 (thiamine) designed for better absorption. Vitamin B6 (pyridoxine) is an essential B vitamin involved in nerve function, immune health, and how your body uses amino acids.

The capsules also contain inactive ingredients—vegetable cellulose, microcrystalline cellulose, stearic acid, and silica—which serve as the capsule shell and binders.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: healthy support for body proteins.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The evidence for this formula's ingredients is mixed. Vitamin B6 is effective for treating sideroblastic anemia (a blood disorder), vitamin B6 deficiency itself, and a rare inherited seizure condition; it's also likely effective for lowering homocysteine (an amino acid linked to heart disease) and possibly effective for pregnancy-related nausea.

Benfotiamine is possibly effective for diabetic nerve pain (neuropathy) but possibly ineffective for kidney damage in diabetes. For L-carnosine, the data we hold shows it's possibly ineffective for autism spectrum disorder and insufficient evidence exists to rate it for age-related mental decline, Alzheimer's disease, athletic performance, cataracts, or cognitive impairment in general.

The evidence, ingredient by ingredient Carnosine Benfotiamine Vitamin B6

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vitamin B6 is well tolerated at doses under 100 mg daily, but high doses taken long-term can cause nerve damage (sensory neuropathy); the risk increases with daily doses over 1,000 mg or total lifetime doses of 1 gram or more, though it can occur at lower doses too. Common side effects at any dose include headache, heartburn, nausea, and loss of appetite.

L-carnosine is generally well tolerated in short-term studies, but long-term safety data are limited; reported side effects include decreased appetite, dry mouth, foot and joint pain, and pneumonia. Benfotiamine is generally well tolerated; a small number of trial participants reported allergic skin reactions or mild stomach discomfort, at rates similar to placebo.

For pregnancy: vitamin B6 is likely safe at normal levels but possibly unsafe at high doses; L-carnosine and benfotiamine lack enough safety data—talk with your doctor before use. For breastfeeding: vitamin B6 is likely safe; L-carnosine safety hasn't been studied, and benfotiamine carries caution.

Side effects, ingredient by ingredient Carnosine Benfotiamine Vitamin B6

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 3 matched ingredients can interact with medications — Vitamin B6, Carnosine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; Parkinson's medications.
  • For scale: 296 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you're on seizure medications (phenytoin, phenobarbital), blood pressure medications, amiodarone for heart rhythm, diabetes medications, or levodopa for Parkinson's. Vitamin B6 at high doses may interfere with seizure control and reduce drug levels, add to blood-pressure-lowering effects, and worsen sun sensitivity with amiodarone; L-carnosine may lower blood sugar further.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This formula may appeal to people concerned with blood sugar control and aging-related cell damage, but it's not right for everyone. If you take seizure medications, blood pressure drugs, diabetes treatments, heart rhythm medication, or levodopa, talk with your doctor or pharmacist before starting it.

Also discuss it if you're pregnant, breastfeeding, or taking high-dose B6 for any reason.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Glycation Protection Formula, straight from the product label.

Brand Life Extension
Barcode (UPC) 737870198765
Net contents 60 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Jun 24, 2016
DSLD ID 60746
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Glycation Protection Formula by Life Extension, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Vegetarian Capsule(s)
Maximum serving Sizes:
1 Vegetarian Capsule(s)
UPC/BARCODE
737870198765
IngredientAmount% DV
L-Carnosine500 mg--
Benfotiamine100 mg--
Vitamin B650 mg2500%

Other ingredients: Vegetable Cellulose, Microcrystalline Cellulose, Stearic Acid, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Read the entire label and follow the directions carefully prior to use. DIRECTIONS: Take one (1) capsule twice daily with or without food, or as directed by a healthcare practitioner.

Storage

Store tightly closed in a cool, dry place.

Precautions

WARNINGS: -Keep out of reach of children.

-Do not exceed recommended dose. -Do not purchase if outer seal is broken or damaged.

-When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

General

Q01987A

General Statements

Healthy Support for the Body's Proteins*

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

Scan for product info

FDA Statement of Identity

Dietary Supplement

Formulation

Non-GMO

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Glycation Protection Formula by Life Extension label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Glycation Protection Formula label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Glycation Protection Formula by Life Extension

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Vegetarian Capsule(s) Dosage formCapsule Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

L-Carnosine

Interacts with
86 drugs
500 mg per serving

Carnosine is a naturally occurring dipeptide (made of beta-alanine and histidine) that acts as an antioxidant and buffer in muscle and brain. It is so...

L-Carnosine monograph & interactions

Benfotiamine

No known
interactions
100 mg per serving

Benfotiamine is a man-made, fat-soluble form of vitamin B1 (thiamine) that the body may absorb more easily than regular thiamine. It is mostly studied...

Benfotiamine monograph & interactions

Vitamin B6

Interacts with
210 drugs
50 mg per serving Form: Pyridoxal 5-Phosphate

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is b...

Vitamin B6 monograph & interactions

Other (inactive) ingredients: Vegetable Cellulose, Microcrystalline Cellulose, Stearic Acid, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Glycation Protection Formula by Life Extension Drug Interactions

Want to check YOUR meds against Glycation Protection Formula?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
296Drugs
291 Moderate 5 Minor

Ingredients driving the most interactions

Vitamin B6 210
L-Carnosine 86

Individual Drug Interactions

The ingredients in Glycation Protection Formula interact with 296 drugs. Click any drug to see the details.

2 of the 3 ingredients in Glycation Protection Formula interact with drugs. Each result below shows which ingredient is responsible. Vitamin B6 L-Carnosine

Each ingredient & the kinds of drugs it affects

For each ingredient in Glycation Protection Formula with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin B65 drug types · 210 drugs

Amiodarone (Cordarone)

Theoretically, vitamin B6 might increase the photosensitivity caused by amiodarone.
Despite initial case reports suggesting that pyridoxine may have a protective effect against amiodarone-induced photosensitivity, preliminary clinical research suggests that pyridoxine may actually exacerbate this adverse effect.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Research in hypertensive rats shows that vitamin B6 can decrease systolic blood pressure. Similarly, clinical research in patients with hypertension shows that taking high doses of vitamin B6 may reduce systolic and diastolic blood pressure, possibly by reducing plasma levels of epinephrine and norepinephrine.

Likelihood Possible Evidence B
Phenobarbital (Luminal)

High doses of vitamin B6 may reduce the levels and clinical effects of phenobarbital.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenobarbital, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenobarbital to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Phenytoin (Dilantin)

High doses of vitamin B6 may reduce the levels and clinical effects of phenytoin.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenytoin, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenytoin to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Levodopa

Vitamin B6 may increase the metabolism of levodopa when taken alone, but not when taken in conjunction with carbidopa.
Vitamin B6 (pyridoxine) enhances the metabolism of levodopa, reducing its clinical effects. However, this interaction does not occur when carbidopa is used concurrently with levodopa (Sinemet). Therefore, it is not likely to be a problem in most people.

Likelihood Unlikely Evidence D
Vitamin B6 full monograph & interactions

L-Carnosine1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking carnosine with antidiabetes drugs might increase the risk of hypoglycemia.
Some, but not all, preliminary clinical research shows that carnosine might reduce fasting blood glucose levels.

Likelihood Possible Evidence D
L-Carnosine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Glycation Protection Formula, from the product label.

Life Extension

See all Life Extension products
Name
Quality Supplements and Vitamins, Inc.
City
Ft. Lauderdale
State
FL
ZipCode
33309
Phone Number
1-866-280-2852
Web Address
LifeExtension.com
Pharmacist Counseling Corner

Glycation Protection Formula by Life Extension: Common Questions

Does Glycation Protection Formula by Life Extension interact with any medications?
Yes. Based on its ingredients, Glycation Protection Formula has a known interaction with 296 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Glycation Protection Formula contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant?
Vitamin B6 in this formula is likely safe at typical dietary levels but possibly unsafe at high doses during pregnancy. L-carnosine and benfotiamine don't have enough safety data available. You and your doctor or pharmacist should discuss whether it's right for you.
Can I take this while breastfeeding?
Vitamin B6 is likely safe while breastfeeding at normal amounts. L-carnosine safety while breastfeeding hasn't been studied, and benfotiamine carries caution. Talk with your doctor or pharmacist before use.
What are the common side effects?
Vitamin B6 may cause headache, heartburn, nausea, or loss of appetite. L-carnosine may cause decreased appetite, dry mouth, foot or joint pain. At the doses in a typical supplement, most people tolerate these ingredients well.
Does L-carnosine actually help with blood sugar?
Some preliminary research suggests L-carnosine might lower fasting blood sugar, which is why people use it for blood sugar control. However, we don't have solid evidence yet that it's effective for this, so it shouldn't replace your doctor's treatment plan.
Is benfotiamine different from regular B1?
Yes. Benfotiamine is a fat-soluble form of vitamin B1 designed to be absorbed more easily by your body than standard B1. It's possibly effective for diabetic nerve pain, though its benefit for other conditions isn't well established.
Can high-dose B6 cause nerve damage?
Yes. Vitamin B6 at very high doses—especially over 1,000 mg daily or with high total lifetime intake—can cause nerve damage (sensory neuropathy), though it can happen even at lower doses. This supplement's B6 content should be safe, but avoid adding extra B6 sources without checking with your doctor.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Glycation Protection Formula is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Glycation Protection Formula label
Go deeper

The Full Monographs Behind Glycation Protection Formula’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Carnosine

Interacts with 86 drugs

Carnosine is a naturally occurring dipeptide (made of beta-alanine and histidine) that acts as an antioxidant and buffer in muscle and brain. It is sold as an anti-aging and performance supp...

Read the full Carnosine monograph → Herb & supplement monograph

Benfotiamine

Benfotiamine is a man-made, fat-soluble form of vitamin B1 (thiamine) that the body may absorb more easily than regular thiamine. It is mostly studied for diabetic nerve problems, but the ev...

Read the full Benfotiamine monograph → Herb & supplement monograph

Vitamin B6

Interacts with 210 drugs

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is best known for helping with pregnancy-rel...

Read the full Vitamin B6 monograph →
Sources

Sources & How We Checked

Glycation Protection Formula's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 38 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Carnosine 5 references
  1. Chengappa KN, Turkin SR, DeSanti S, et al. A preliminary, randomized, double-blind, placebo-controlled trial of L-carnosine to improve cognition in schizophrenia. Schizophr Res 2012;142(1-3):145-52. PubMed
  2. Karkabounas S, Papadopoulos N, Anastasiadou C, et al. Effects of a-lipoic Acid, carnosine, and thiamine supplementation in obese patients with type 2 diabetes mellitus: A randomized, double-blind study. J Med Food. 2018;21(12):1197-1203.
  3. Peng W, Mao P, Liu L, et al. Effect of carnosine supplementation on lipid profile, fasting blood glucose, HbA1C and insulin resistance: a systematic review and meta-analysis of long-term randomized controlled trials. Complement Ther Med 2020;48:102241. PubMed
  4. Siriwattanasit N, Satirapoj B, Supasyndh O. Effect of oral carnosine supplementation on urinary TGF-ß in diabetic nephropathy: a randomized controlled trial. BMC Nephrol 2021;22(1):236. PubMed
  5. Sureshkumar K, Durairaj M, Srinivasan K, et al. Effect of L-Carnosine in Patients with Age-Related Diseases: A Systematic Review and Meta-Analysis. Front Biosci (Landmark Ed) 2023;28(1):18. PubMed

See these in context on the Carnosine monograph →

Benfotiamine 1 reference
  1. Stracke H, Gaus W, Achenbach U, Federlin K, Bretzel RG. Benfotiamine in diabetic polyneuropathy (BENDIP): results of a randomised, double blind, placebo-controlled clinical study. Exp Clin Endocrinol Diabetes 2008;116(10):600-5. PubMed

See these in context on the Benfotiamine monograph →

Vitamin B6 32 references
  1. Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
  2. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  3. Geerling BJ, Dagnelie PC, Badart-Smook A, et al. Diet as a risk factor for the development of ulcerative colitis. Am J Gastroenterol 2000;95:1008-13. PubMed
  4. South M. Neonatal seizures after pyridoxine use -- reply. Lancet 1999;354:2083. PubMed
  5. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  6. Baxter P, Aicardi J. Neonatal seizures after pyridoxine use. Lancet 1999;354:2082-3. PubMed
  7. Bendich A, Cohen M. Vitamin B6 safety issues. Ann N Y Acad Sci 1990;585:321-30.
  8. Schaumburg H, Kaplan J, Windebank A. Sensory neuropathy from pyridoxine abuse. A new megavitamin syndrome. N Engl J Med 1983;309:445-8. PubMed
  9. Gordon N. Pyridoxine dependency: an update. Dev Med Child Neurol 1997;39:63-5. PubMed
  10. Lewis PJ. Pain in the hand and wrist. Pyridoxine supplements may help patients with carpal tunnel syndrome. BMJ 1995;310:1534. PubMed
  11. Kaufman G. Pyridoxine against amiodarone-induced photosensitivity (letter). Lancet 1984;1:51-2. PubMed
  12. Mulrow JP, Mulrow CD, McKenna WJ. Pyridoxine and amiodarone-induced photosensitivity. Ann Intern Med 1985;103:68-9. PubMed
  13. Kawada A, Kashima A, Shiraishi H, et al. Pyridoxine-induced photosensitivity and hypophosphatasia. Dermatology 2000;201:356-60.. PubMed
  14. Vasile A, Goldberg R, Kornberg B. Pyridoxine toxicity: report of a case. J Am Osteopath Assoc 1984;83:790-1. DOI
  15. Hansson O, Sillanpaa M. Pyridoxine and serum concentration of phenytoin and phenobarbitone. Lancet 1976;1:256. DOI
  16. Jansen T, Romiti R, Kreuter A, Altmeyer P. Rosacea fulminans triggered by high-dose vitamins B6 and B12. J Eur Acad Dermatol Venereol 2001;15:484-5..
  17. Chittumma P, Kaewkiattikun K, Wiriyasiriwach B. Comparison of the effectiveness of ginger and vitamin B6 for treatment of nausea and vomiting in early pregnancy: a randomized double-blind controlled trial. J Med Assoc Thai 2007;90:15-20.
  18. Hatzitolios, A., Iliadis, F., Katsiki, N., and Baltatzi, M. Is the anti-hypertensive effect of dietary supplements via aldehydes reduction evidence based? A systematic review. Clin Exp.Hypertens. 2008;30(7):628-639. PubMed
  19. Vasdev, S., Ford, C. A., Parai, S., Longerich, L., and Gadag, V. Dietary vitamin B6 supplementation attenuates hypertension in spontaneously hypertensive rats. Mol.Cell Biochem. 1999;200(1-2):155-162.
  20. de, Vogel S., Dindore, V., van, Engeland M., Goldbohm, R. A., van den Brandt, P. A., and Weijenberg, M. P. Dietary folate, methionine, riboflavin, and vitamin B-6 and risk of sporadic colorectal cancer. J Nutr 2008;138(12):2372-2378. PubMed
  21. Hagen, I., Nesheim, B. I., and Tuntland, T. No effect of vitamin B-6 against premenstrual tension. A controlled clinical study. Acta Obstet.Gynecol.Scand. 1985;64(8):667-670. PubMed
  22. Aybak, M., Sermet, A., Ayyildiz, M. O., and Karakilcik, A. Z. Effect of oral pyridoxine hydrochloride supplementation on arterial blood pressure in patients with essential hypertension. Arzneimittelforschung. 1995;45(12):1271-1273.
  23. Lal, K. J., Dakshinamurti, K., and Thliveris, J. The effect of vitamin B6 on the systolic blood pressure of rats in various animal models of hypertension. J Hypertens. 1996;14(3):355-363. PubMed
  24. Lauritzen CH, Reuter HD, Repges R, Bohnert K, and Schmidt U. Treatment of premenstrual tension syndrome with Vitex agnus castus. Controlled, double-blind study versus pyridoxine. Phytomed 1997;4(3):183-189. PubMed
  25. Fonseca VA, Lavery LA, Thethi TK, et al. Metanx in type 2 diabetes with peripheral neuropathy: A randomized trial. Am J Med 2013;126(2):141-9. PubMed
  26. Hankey GJ, Eikelboom JW, Yi Q, et al. Treatment with B vitamins and incidence of cancer in patients with previous stroke or transient ischemic attack: Results of a randomized placebo-controlled trial. Stroke 2012;43(6):1572-7. PubMed
  27. Hoyer-Kuhn H, Kohbrok S, Volland R, Franklin J, Hero B, Beck BB, Hoppe B. Vitamin B6 in primary hyperoxaluria I: first prospective trial after 40 years of practice. Clin J Am Soc Nephrol. 2014 Mar;9(3):468-77. PubMed
  28. Mahmoud A, Tabassum S, Al Enazi S, et al. Amelioration of levetiracetam-induced behavioral side effects by pyridoxine. A randomized double blind controlled study. Pediatr Neurol 2021;119:15-21. PubMed
  29. Gupta M, Gallante B, Bamberger JN, et al. Prospective randomized evaluation of idiopathic hyperoxaluria treatments. J Endourol 2021;35(12):1844-1851. PubMed
  30. Li H, Chen M, Liang S, et al. Excessive vitamin B6 during treatment is related to poor prognosis of patients with nasopharyngeal carcinoma: A U-shaped distribution suggests low dose supplement. Clin Nutr 2021;40(4):2293-2300. PubMed
  31. Tanigawa J, Nabatame S, Tominaga K, et al. High-dose pyridoxine treatment for inherited glycosylphosphatidylinositol deficiency. Brain Dev 2021;43(6):680-687. PubMed
  32. Committee on Practice Bulletins-Obstetrics. ACOG Practice Bulletin No. 189: Nausea And Vomiting Of Pregnancy. Obstet Gynecol. 2018;131(1):e15-e30. PubMed

See these in context on the Vitamin B6 monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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