Interactions on record — worth a quick check against your medications. Based on 1 of 5 ingredients. Check your meds →
Dietary supplement

Granular Theralac Ingredients & Drug Interactions

by Master Supplements

Granular Theralac label
See full label image
Powder Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Granular Theralac against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Granular Theralac is a dietary supplement by Master Supplements with 5 active ingredients. Its ingredients are commonly taken for digestive health and balance, diarrhea (including antibiotic-related), vaginal yeast and bacterial infections.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lactobacillus acidophilus. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Granular Theralac by Master Supplements

Ask about any prescription or over-the-counter medication and we check it for interactions with Granular Theralac by Master Supplements — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Granular Theralac by Master Supplements

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 5 active ingredients.
  • “Proprietary Probiotic Blend” is a proprietary blend — the label gives one combined amount (108.75 mg) without saying how much of each component you get.

Granular Theralac is a five-ingredient probiotic powder centered on a proprietary blend of live bacterial strains. The active ingredients are Bifidobacterium animalis lactis Bi-07, Lactobacillus acidophilus, Bifidobacterium animalis lactis, Lactobacillus rhamnosus, and Lactobacillus paracasei — all meant to support digestive and gut health.

The inactive ingredients include microcrystalline cellulose, sodium alginate, silicon dioxide, ascorbic acid, LactoStim, and calcium silicate, which are fillers and stabilizers in the powder.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: High potency probiotic digestive health.
  • We looked for evidence on: Antibiotic-associated diarrhea, Bacterial vaginosis, Clostridioides difficile infection, Constipation, Irritable bowel syndrome (IBS), Lactose intolerance — and 4 related terms.
  • The strongest evidence on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Antibiotic-associated diarrhea (Natural Medicines).
  • Also on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Bacterial vaginosis, Irritable bowel syndrome (IBS).
  • Also on file: Lactobacillus Acidophilus is rated "Insufficient Reliable Evidence To Rate" for Constipation, Lactose intolerance, Rotaviral diarrhea, Travelers' diarrhea.

Lactobacillus acidophilus, one of the active ingredients here, is rated possibly effective for irritable bowel syndrome (IBS), Helicobacter pylori infection, antibiotic-associated diarrhea, and bacterial vaginosis. It's rated possibly ineffective for atopic disease, and we don't have enough reliable evidence to rate it for acute respiratory distress syndrome.

The other four probiotic strains in this product don't have effectiveness ratings on file, so we can't speak to what they're shown to do.

The evidence, ingredient by ingredient Lactobacillus Acidophilus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactobacillus acidophilus is generally well tolerated in healthy adults and children. Some people taking it with other probiotics report mild gastrointestinal side effects like stomach discomfort, abdominal pain, gas, bloating, or diarrhea, though these are uncommon.

In rare cases, live L. acidophilus organisms have been linked to serious infections like bacteremia or sepsis, but these events are thought to occur mainly in people whose digestive barriers are already compromised. Check with your doctor before starting, especially if you're immunocompromised or have a serious underlying illness.

We have no pregnancy or breastfeeding data on file for any ingredient in this product — talk with your doctor or pharmacist for personalized advice if you're pregnant or nursing.

Side effects, ingredient by ingredient Lactobacillus Acidophilus

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Lactobacillus Acidophilus.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Antibiotic drugs are the main medication type to check before taking this product — they can reduce how well the Lactobacillus acidophilus in it works. We could not check the other four probiotic strains for interactions, so run your complete medication list through the checker below.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Granular Theralac is a multi-strain probiotic designed for digestive support. If you take antibiotics, space them out from this product so the live organisms aren't killed off.

You should double-check your medications with the tool on this page, and talk with your pharmacist if you're immunocompromised, pregnant, nursing, or have serious digestive or immune issues.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Granular Theralac, straight from the product label.

Brand Master Supplements
Barcode (UPC) 804879230885
Net contents 30 Gram(s)
Market status On market
Date entered into DSLD Jul 24, 2025
DSLD ID 336274
Product type Non-nutrient/non-botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Granular Theralac by Master Supplements, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.75 Gram(s)
Maximum serving Sizes:
0.75 Gram(s)
Servings per container
40
UPC/BARCODE
804879230885
IngredientAmount% DV
Proprietary Probiotic Blend108.75 mg--
Bifidobacterium animalis lactis Bi-070 NP--
Lactobacillus acidophilus0 NP--
Bifidobacterium animalis lactis0 NP--
Lactobacillus rhamnosus0 NP--
Lactobacillus paracasei0 NP--

Other ingredients: Microcrystalline Cellulose, Sodium Alginate, Silicon Dioxide, Ascorbic Acid, LactoStim, Calcium Silicate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Fold or gently stir a 1/4 teaspoon into any soft food or beverage of your choice. When taking with antibiotics allow at least 3 hours of separation.

Formula

Granular Theralac is a high potency probiotic powder protected by 7 U.S. patents covering prebiotic stimulation with LactoStim and acid-proof delivery.

Broad spectrum probiotic Patented prebiotic 5 Probiotics 25 Billion CFU

Formulation

Each batch is laboratory tested to meet strict quality control standards.

100% Money Back Guarantee

Gluten free GMO free

Vegan

Supports regularity Deep delivery

Contains No: Milk, Eggs, Gluten, Wheat, Soy, Casein, Nuts, Seafood, or Beef Products.

Storage

Potency is guaranteed at the time of expiration when kept refrigerated.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

Patented prebiotic

General Statements

CFU = Colony Forming Units

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Granular Theralac by Master Supplements label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Granular Theralac label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Granular Theralac by Master Supplements

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size0.75 Gram(s) Dosage formPowder Servings per container40 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Probiotic Blend

108.75 mg per serving
  • › Bifidobacterium animalis lactis Bi-07
  • › Lactobacillus acidophilus
  • › Bifidobacterium animalis lactis
  • › Lactobacillus rhamnosus
  • › Lactobacillus paracasei

Other (inactive) ingredients: Microcrystalline Cellulose, Sodium Alginate, Silicon Dioxide, Ascorbic Acid, LactoStim, Calcium Silicate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Granular Theralac by Master Supplements Drug Interactions

Want to check YOUR meds against Granular Theralac?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Lactobacillus acidophilus 182

Individual Drug Interactions

The ingredients in Granular Theralac interact with 182 drugs. Click any drug to see the details.

1 of the 5 ingredients in Granular Theralac interact with drugs. Each result below shows which ingredient is responsible. Lactobacillus acidophilus

Each ingredient & the kinds of drugs it affects

For each ingredient in Granular Theralac with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Lactobacillus acidophilus1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D
Lactobacillus acidophilus full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Granular Theralac, from the product label.

Master Supplements

See all Master Supplements products
Name
Master Supplements, Inc.
City
Victoria
State
MN
ZipCode
55386
Phone Number
800 926-2961
Web Address
master-supplements.com
Pharmacist Counseling Corner

Granular Theralac by Master Supplements: Common Questions

Does Granular Theralac by Master Supplements interact with any medications?
Yes. Based on its ingredients, Granular Theralac has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Granular Theralac contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will antibiotics ruin this probiotic?
Antibiotics can kill off a lot of the live Lactobacillus acidophilus organisms in this product, making it less effective. Ask your pharmacist about timing — typically spacing them several hours apart helps preserve the probiotic's benefit.
What is L. acidophilus supposed to do?
Lactobacillus acidophilus is possibly effective for irritable bowel syndrome, antibiotic-associated diarrhea, Helicobacter pylori infection, and bacterial vaginosis. It's a live bacteria meant to support your gut health and digestive balance.
Can this cause side effects?
Most people tolerate it well, but some experience mild stomach discomfort, gas, bloating, or diarrhea when taking it with other probiotics — though these are uncommon. Serious infections from L. acidophilus are very rare and typically occur only in people with severely weakened immunity.
Is it safe if I'm pregnant or breastfeeding?
We don't have pregnancy or breastfeeding safety data on file for any ingredient in this product. Talk with your doctor or pharmacist — they can help you decide based on your individual situation.
Why can't you check all the ingredients for drug interactions?
We hold detailed monograph data on Lactobacillus acidophilus, but the other four probiotic strains in this blend don't have interaction data on file yet. That doesn't mean they're safe or unsafe — just that we haven't mapped their interactions.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Granular Theralac is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Granular Theralac label
Go deeper

The Full Monographs Behind Granular Theralac’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lactobacillus Acidophilus

Interacts with 182 drugs

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...

Read the full Lactobacillus Acidophilus monograph →
Sources

Sources & How We Checked

Granular Theralac's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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