Interactions on record — worth a quick check against your medications. Based on 2 of 5 ingredients. Check your meds →
Dietary supplement

Helladrol Ingredients & Drug Interactions

by Innovative

Helladrol label
See full label image
Tablet Or Pill Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Helladrol against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Helladrol is a dietary supplement by Innovative with 5 active ingredients. Its ingredients are commonly taken for lowering estrogen levels, post-cycle therapy after steroid or prohormone use, reducing gynecomastia ('gyno').Based on those ingredients, 12 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are 4 Androstene-3b-ol, 17-One, Androsta-3,5-Diene-7,17-Dione. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Helladrol by Innovative

Ask about any prescription or over-the-counter medication and we check it for interactions with Helladrol by Innovative — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Helladrol by Innovative

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 5 active ingredients.
  • “Helladrol Proprietary Prohormone Matrix” is a proprietary blend — the label gives one combined amount (150 mg) without saying how much of each component you get.

Helladrol contains 5 active ingredients designed as prohormones—compounds your body may convert into other hormonal substances. The two we can fully identify are Androsta-3,5-Diene-7,17-Dione (also called Arimistane) and 4-Androsterone.

The product also includes three additional prohormone compounds whose exact effects aren't detailed here. Beyond the actives, the tablet contains common inactive ingredients like microcrystalline cellulose (a binder), phosphatidylcholine, and several other fillers and capsule materials.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Ultimate hardcore prohormone for serious athletes.
  • We looked for evidence on: Athletic performance, Muscle strength, bodybuilding, testosterone support, performance enhancement.
  • The closest evidence on file: Arimistane is rated "Insufficient Reliable Evidence To Rate" for Athletic performance (Natural Medicines).
  • Also on file: Arimistane is rated "Insufficient Reliable Evidence To Rate" for Muscle strength.

The data we hold shows insufficient reliable evidence to rate Androsta-3,5-Diene-7,17-Dione for athletic performance, erectile dysfunction, muscle strength, sexual arousal, or obesity. For 4-Androsterone, no effectiveness ratings are on file.

In short, while this product is marketed for performance and body composition, the evidence backing these claims isn't established in our data.

The evidence, ingredient by ingredient Arimistane 4-androsterone

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both main ingredients come with caution flags. Androsta-3,5-Diene-7,17-Dione is a hormone-altering drug with very little safety data, and regulators warn against aromatase inhibitor supplements.

4-Androsterone may theoretically cause serious anabolic steroid–like side effects including stroke, kidney failure, and liver injury, though detailed adverse effect information is sparse. Prohormones in general can disrupt your hormone balance, strain the liver, and affect cholesterol levels—and long-term safety is not well studied.

This product is rated possibly unsafe in pregnancy because lowering estrogen during pregnancy could harm the developing baby. There isn't enough data to know whether it's safe while breastfeeding, so you should avoid use then too.

Side effects, ingredient by ingredient Arimistane 4-androsterone

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — 4-androsterone, Arimistane.
  • The most serious interaction on file is rated Moderate.
  • For scale: 12 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Helladrol, double-check with your doctor or pharmacist if you take aromatase inhibitors (used mainly for hormone-sensitive cancers) or testosterone in any form—including prescription testosterone, other supplements, or any other testosterone product. No other medication interactions are documented for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Helladrol is a prohormone product meant to shift your hormonal environment—it's not a conventional supplement. If you take aromatase inhibitors, testosterone, or any other hormone therapy, you should check with your doctor or pharmacist before starting this.

Even if you don't take those, the overall safety profile is limited and the effectiveness claims aren't well backed by evidence. Talk it over with your own doctor before deciding whether this is right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Helladrol, straight from the product label.

Brand Innovative
Barcode (UPC) 811836020984
Net contents 60 Cylcosome Tablet(s)
Market status On market
Date entered into DSLD Apr 22, 2021
DSLD ID 248856
Product type Non-nutrient/non-botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Helladrol by Innovative, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
60
UPC/BARCODE
811836020984
IngredientAmount% DV
Androsta-3,5-Diene-7,17-Dione0 NP--
Helladrol Proprietary Prohormone Matrix150 mg--
4 Androstene-3b-ol, 17-One0 NP--
3-hydroxy-17-oxo-5-androstane0 NP--
17Beta-(1-ketoethyl)-Delta-1,4-androstadiene0 NP--
1,4 Androstene-3b-ol, 17-one0 NP--

Other ingredients: Microcrystalline Cellulose, Phosphatidylcholine, Hydroxy Propylmethylcellulose, Phytosterols, Stearic Acid, Magnesium Stearate, Silica, FD&C Red #3

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Ultimate hardcore prohormone

Helladrol is the newest prohormone from the innovative line of products.

Precautions

Warning: Warning: Anabolic compounds are for the serious athletes and not intended for anyone under the age 18 or women of any age.

Do not use if you have liver problems, kidney, thyroid, high blood pressure, diabetes, heart disease or if you are taking MAOI's. If you are on medication or medical treatment consult a licensed physician prior to use.

Do not use more than 4-6 weeks w/o a 8 week break between cycles. Tested athletes for performance enhancing substances should consult w/their sanctioning body prior to use as this product may cause a false reactive result. This product consist of Methylated compounds and upon completion the use of a proper Post Cycle Therapy (PCT) protocol is required. No exceptions.

Keep out of the reach of children.

FDA Disclaimer Statement

These statements have not been approved by the FDA. This product is not intended to diagnose, treat, cure or prevent any diseases.

Storage

Store in a cool dry place away from moisture and sunlight.

Formulation

Made in USA

The world's hottest prohormone for strength, size and hardness!

Helladrol is the product of choice for people looking to gain as much strength, power, endurance, hardness, and definition without holding excess water in the process. The strength and muscle gains that come from a short cycle of Helladrol have been known to leave most users nothing short of speechless. Gains with Helladrol are hard and lean because it does not aromatize to any type of estrogen. You can expect lean hard muscle gains as well as strength gains on Helladrol.

Innovative providing the industry with "cutting edge" products to help deliver the maximum levels of physical performance possible. Innovative Labs is fully compliant with all governing regulations enabling safe and effective compounds to be produced to the highest purity & quality levels through certified U.S. analytical labs & GMP approved facilities.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: Take 2-3 tablets daily with food. Do not exceed 4 tablets per day.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Helladrol by Innovative label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Helladrol label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Helladrol by Innovative

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Helladrol Proprietary Prohormone Matrix

150 mg per serving

Other (inactive) ingredients: Microcrystalline Cellulose, Phosphatidylcholine, Hydroxy Propylmethylcellulose, Phytosterols, Stearic Acid, Magnesium Stearate, Silica, FD&C Red #3. These complete the product’s ingredient list but are not active constituents.

Interaction report

Helladrol by Innovative Drug Interactions

Want to check YOUR meds against Helladrol?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
12Drugs
12 Moderate

Ingredients driving the most interactions

4 Androstene-3b-ol, 17-One 8
Androsta-3,5-Diene-7,17-Dione 4

Individual Drug Interactions

The ingredients in Helladrol interact with 12 drugs. Click any drug to see the details.

2 of the 5 ingredients in Helladrol interact with drugs. Each result below shows which ingredient is responsible. 4 Androstene-3b-ol, 17-One Androsta-3,5-Diene-7,17-Dione

Each ingredient & the kinds of drugs it affects

For each ingredient in Helladrol with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

4 Androstene-3b-ol, 17-One1 drug type · 8 drugs

Testosterone

4-Androsterone is purportedly converted to testosterone and other androgens upon ingestion. Theoretically, taking 4-androsterone with testosterone may increase the risk for additive adverse effects such as mood disturbances and cardiovascular, kidney, or liver problems.

Likelihood Possible Evidence D
4 Androstene-3b-ol, 17-One full monograph & interactions

Androsta-3,5-Diene-7,17-Dione1 drug type · 4 drugs

Aromatase Inhibitors

It is believed that Arimistane inhibits the aromatase enzyme, which may interact with other aromatase inhibitors. This interaction could potentially increase the risk of side effects associated with low estrogen levels or from additive side effects, such as an increased risk of liver toxicity. It is recommended to consult with a healthcare provider before combining Arimistane with other aromatase inhibitors to assess the potential risks and benefits.

Likelihood Probable Evidence C
Androsta-3,5-Diene-7,17-Dione full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Helladrol, from the product label.

Innovative

See all Innovative products
Name
Innovative Laboratories
Street Address
6015-B Unity Drive
City
Norcross
State
GA
ZipCode
30071
Phone Number
(800) 981-4783
Web Address
WWW.innovativelaboratories.net
Pharmacist Counseling Corner

Helladrol by Innovative: Common Questions

Does Helladrol by Innovative interact with any medications?
Yes. Based on its ingredients, Helladrol has a known interaction with 12 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Helladrol contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Helladrol if I'm pregnant or breastfeeding?
No. The first ingredient is rated possibly unsafe in pregnancy because lowering estrogen during pregnancy could harm the baby. The second ingredient may pose risks to a nursing infant, and there isn't enough data to know either way. Avoid use in both cases.
Does Helladrol actually work for building muscle or athletic performance?
The data we hold shows insufficient reliable evidence to say whether it works for muscle strength, athletic performance, or the other health claims made for it. The science backing these uses isn't established yet.
What's a prohormone, and why is this product different from a regular supplement?
A prohormone is a compound your body may convert into hormones like testosterone. Unlike most supplements, prohormones directly alter your hormone balance—which is why they carry more serious cautions and are flagged by regulators.
What are the main side effects I should watch for?
The product may theoretically cause serious side effects similar to anabolic steroids, including stroke, kidney failure, and liver injury. Prohormones in general can also disrupt hormone balance, strain the liver, and affect cholesterol. Because safety data are limited, you should discuss any concerns with your doctor.
I'm on a cancer medication (aromatase inhibitor). Can I take this?
No, not without checking with your doctor first. Arimistane in this product may interact with aromatase inhibitor drugs, potentially increasing the risk of side effects tied to low estrogen or liver damage.
What does 'Helladrol Proprietary Prohormone Matrix' mean?
That's the label's way of grouping several prohormone compounds together. Three of them—3-hydroxy-17-oxo-5-androstane, 17Beta-(1-ketoethyl)-Delta-1,4-androstadiene, and 1,4 Androstene-3b-ol, 17-one—we couldn't find detailed safety or interaction data for.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Helladrol label
Go deeper

The Full Monographs Behind Helladrol’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Arimistane

Interacts with 4 drugs

Arimistane (sometimes sold as Estrovade) is a synthetic aromatase inhibitor marketed as a dietary supplement to lower estrogen and raise testosterone, often during or after steroid or prohor...

Read the full Arimistane monograph → Herb & supplement monograph

4-androsterone

Interacts with 8 drugs

4-Androsterone (sometimes called 4-DHEA) is a lab-made prohormone marketed to bodybuilders as a way to raise testosterone and build muscle, but human studies are very limited and it carries...

Read the full 4-androsterone monograph →
Sources

Sources & How We Checked

Helladrol's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Arimistane 1 reference
  1. Joseph JF, Parr MK. Synthetic androgens as designer supplements. Curr Neuropharmacol. 2015;13(1):89-100. PubMed

See these in context on the Arimistane monograph →

4-androsterone 3 references
  1. Anabolic Steroids and Other Appearance and Performance Enhancing Drugs (APEDs) — NIH National Institute on Drug Abuse Source
  2. Dietary Supplements for Exercise and Athletic Performance — NIH Office of Dietary Supplements Source
  3. DHEA — MedlinePlus Source

See these in context on the 4-androsterone monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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