Hemp Seed Oil 1000 mg Ingredients & Drug Interactions
by NusaPure
What is this page for?
First and foremost: checking Hemp Seed Oil 1000 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Hemp Seed Oil 1000 mg is a dietary supplement by NusaPure with 1 active ingredient. Its ingredients are commonly taken for plant-based protein source, heart health support, skin and hair health.Based on those ingredients, 1,018 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Hemp seed Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Hemp Seed Oil 1000 mg by NusaPure
Ask about any prescription or over-the-counter medication and we check it for interactions with Hemp Seed Oil 1000 mg by NusaPure — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Hemp Seed Oil 1000 mg by NusaPure
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This product contains 5 active ingredients, primarily delivered through hemp seed oil and its component fatty acids: stearic acid, linolenic acid, alpha-linolenic acid, palmitic acid, and oleic acid. The capsule also holds inactive ingredients—starch, vegetable glycerin, and purified water—that help form and fill the supplement.
Does it work?
Moderate evidence
Oleic acid, one of the active ingredients here, is rated possibly effective for high cholesterol (hypercholesterolemia) and coronary heart disease prevention based on available evidence. We don't have effectiveness data on file for the other fatty acids in this product, so we can't speak to how well they work for any particular health goal.
How safe is it?
Some data gaps
Oleic acid is generally recognized as safe when you get it from food sources like olive oil in normal amounts. However, concentrated supplement doses—like those in this product—haven't been well studied, especially during pregnancy or while breastfeeding.
There are no reported adverse effects documented for this ingredient in our data.
Meds to double-check
Moderate interaction found
If you take antidiabetes drugs (oral blood sugar medication), double-check this product with your doctor or pharmacist before starting—oleic acid may increase how strongly those drugs work, which could lower your blood sugar more than intended.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and some safety-information gaps remain.
If you're looking to support cholesterol or heart health and don't take antidiabetes drugs, this product is worth discussing with your doctor. If you do take blood sugar medication, check with your pharmacist or doctor first—oleic acid might enhance those drugs' effects.
Either way, talk it over with your own healthcare provider before you start.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Hemp Seed Oil 1000 mg, straight from the product label.
| Brand | NusaPure |
|---|---|
| Barcode (UPC) | X001V62NW1 |
| Net contents | 180 Veg Cap(s) |
| Market status | On market |
| Date entered into DSLD | Oct 24, 2022 |
| DSLD ID | 274981 |
| Product type | Fat/fatty Acid |
| Supplement form | Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Hemp Seed Oil 1000 mg by NusaPure, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Stearic Acid | 0 NP | -- |
| Linolenic Acid | 0 NP | -- |
| Alpha-Linolenic Acid | 0 NP | -- |
| Hemp seed Oil | 1000 mg | -- |
| Palmitic Acid | 0 NP | -- |
| Oleic Acid | 0 NP | -- |
Other ingredients: Starch, Vegetable Glycerin, Water, Purified
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Directions: For adults, take (2) capsules daily, preferably with meals.
Precautions
Warning: If you are pregnant, nursing, or taking any medications, consult your doctor before use.
Discontinue use and consult your doctor if any adverse reactions occur.
Not intended for use by persons under the age of 18. Keep out of reach of children.
Produced in a GMP facility that processes other ingredients containing these allergens.
Storage
Store in cool dry place. Avoid excessive heat or moisture.
Formulation
Natural color variation may occur in this product.
GMO Free Made with non-GMO Ingredients Gluten Free FDA Registered Facility
Assembled in USA Natural Supports healthy skin & nails Supports healthy joints
Supports healthy skin & nails Supports healthy joints Max Strength
Allergen Information: Contains no yeast, wheat, gluten, soy, corn, milk, egg, fish or shellfish ingredients.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Seals/Symbols
Premium Quality Assembled in USA GMO Free Made with non-GMO Ingredients Gluten Free FDA Registered Facility
Manufactured in a cGMP Inspected Facility
Formula
Hemp Seed Oil 1000 mg per serving Contains Omega 3,6,9
Each serving may typically have the following naturally occurring amounts of polyunsaturated fats and monounsaturated fats: Alpha-Linolenic Acid (Omega-3) 21%; Linoleic Acid and Gamma-Linolenic Acid (GLA) (Omega-6) 57%; Oleic Acid (omega-9) 13%; other (saturated) 9%
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Hemp Seed Oil 1000 mg by NusaPure label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Hemp Seed Oil 1000 mg by NusaPure
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size2 Veggie Softgel(s) Dosage formCapsule Servings per container180 Amounts shown are per serving.
Hemp seed Oil
Interacts with938 drugs
Hemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for...
Hemp seed Oil monograph & interactions- › Stearic Acid
- › Linolenic Acid
- › Alpha-Linolenic Acid
- › Palmitic Acid
- › Oleic Acid
Other (inactive) ingredients: Starch, Vegetable Glycerin, Water, Purified. These complete the product’s ingredient list but are not active constituents.
Hemp Seed Oil 1000 mg by NusaPure Drug Interactions
HelloPharmacist Interaction Report
NusaPure Hemp Seed Oil 1000 mg contains oleic acid, which may interact with antidiabetes drugs.
Research suggests that oleic acid could theoretically boost the effects of blood sugar–lowering medications (oral hypoglycemic drugs), which means your blood sugar might drop more than expected. The other active ingredients in this product—stearic acid, linolenic acid, alpha-linolenic acid, and palmitic acid—could not be checked against our interaction database, so we have no documented interaction data for them.
Read the full breakdown — every affected drug type, severity by severity
Additionally, several other ingredients in this blend have not been evaluated for drug interactions in our current data. We can only tell you what we found for oleic acid.
If you take any antidiabetes medication, run your full medication list through the tool below before starting this product, and talk with your doctor or pharmacist about whether added blood sugar monitoring might be needed.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Hemp Seed Oil 1000 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Hemp Seed Oil 1000 mg interact with 1,018 drugs. Click any drug to see the details.
1 of the 1 ingredient in Hemp Seed Oil 1000 mg interact with drugs. Each result below shows which ingredient is responsible. Hemp seed Oil
AcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Hemp Seed Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Oleic AcidAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oleic acid might increase the effects of antidiabetes drugs.
Read the full Oleic Acid + Acarbose interactionAcetohexamideDymelor
How Acetohexamide interacts with Hemp Seed Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Oleic AcidAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oleic acid might increase the effects of antidiabetes drugs.
Read the full Oleic Acid + Acetohexamide interactionAlbiglutideTanzeum
How Albiglutide interacts with Hemp Seed Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Oleic AcidAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oleic acid might increase the effects of antidiabetes drugs.
Read the full Oleic Acid + Albiglutide interactionAlogliptinNesina
How Alogliptin interacts with Hemp Seed Oil 1000 mg — through 2 ingredients. Tap an ingredient for the detail:
Oleic AcidAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oleic acid might increase the effects of antidiabetes drugs.
Read the full Oleic Acid + Alogliptin interactionHemp Seed OilCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Seed Oil + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Hemp Seed Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Oleic AcidAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oleic acid might increase the effects of antidiabetes drugs.
Read the full Oleic Acid + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Hemp Seed Oil 1000 mg — through 2 ingredients. Tap an ingredient for the detail:
Oleic AcidAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oleic acid might increase the effects of antidiabetes drugs.
Read the full Oleic Acid + Alogliptin, Pioglitazone interactionHemp Seed OilCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Seed Oil + Alogliptin, Pioglitazone interactionAntidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
How Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interacts with Hemp Seed Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Oleic AcidAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oleic acid might increase the effects of antidiabetes drugs.
Read the full Oleic Acid + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionBazedoxifene Acetate, Conjugated EstrogensDuavee
How Bazedoxifene Acetate, Conjugated Estrogens interacts with Hemp Seed Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Seed OilEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Hemp Seed Oil + Bazedoxifene Acetate, Conjugated Estrogens interactionCanagliflozinInvokana
How Canagliflozin interacts with Hemp Seed Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Oleic AcidAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oleic acid might increase the effects of antidiabetes drugs.
Read the full Oleic Acid + Canagliflozin interactionCanagliflozin, MetforminInvokamet
How Canagliflozin, Metformin interacts with Hemp Seed Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Oleic AcidAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oleic acid might increase the effects of antidiabetes drugs.
Read the full Oleic Acid + Canagliflozin, Metformin interactionCanagliflozin, Metformin HydrochlorideInvokamet XR
How Canagliflozin, Metformin Hydrochloride interacts with Hemp Seed Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Oleic AcidAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oleic acid might increase the effects of antidiabetes drugs.
Read the full Oleic Acid + Canagliflozin, Metformin Hydrochloride interactionChlorpropamideChlorpropam, Diabinese
How Chlorpropamide interacts with Hemp Seed Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Oleic AcidAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oleic acid might increase the effects of antidiabetes drugs.
Read the full Oleic Acid + Chlorpropamide interactionConjugated EstrogensCenestin, Enjuvia, Premarin, Premarin Vaginal Cream
How Conjugated Estrogens interacts with Hemp Seed Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Seed OilCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Seed Oil + Conjugated Estrogens interactionConjugated Estrogens, Medroxyprogesterone AcetatePremplus, Prempro
How Conjugated Estrogens, Medroxyprogesterone Acetate interacts with Hemp Seed Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Seed OilEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Hemp Seed Oil + Conjugated Estrogens, Medroxyprogesterone Acetate interactionConjugated Estrogens, MeprobamatePMB 200, PMB 400
How Conjugated Estrogens, Meprobamate interacts with Hemp Seed Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Seed OilCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Seed Oil + Conjugated Estrogens, Meprobamate interactionConjugated Estrogens, MethyltestosteronePremarin with Methyltestosterone
How Conjugated Estrogens, Methyltestosterone interacts with Hemp Seed Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Seed OilEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Hemp Seed Oil + Conjugated Estrogens, Methyltestosterone interactionCyproterone Acetate, Ethinyl EstradiolDiane-35, Dianette
How Cyproterone Acetate, Ethinyl Estradiol interacts with Hemp Seed Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Seed OilEstrogens, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Hemp Seed Oil + Cyproterone Acetate, Ethinyl Estradiol interactionDapagliflozinFarxiga
How Dapagliflozin interacts with Hemp Seed Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Oleic AcidAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oleic acid might increase the effects of antidiabetes drugs.
Read the full Oleic Acid + Dapagliflozin interactionDapagliflozin Propanediol, MetforminXigduo XR
How Dapagliflozin Propanediol, Metformin interacts with Hemp Seed Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Oleic AcidAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oleic acid might increase the effects of antidiabetes drugs.
Read the full Oleic Acid + Dapagliflozin Propanediol, Metformin interactionDapagliflozin Propanediol, Saxagliptin HydrochlorideQtern
How Dapagliflozin Propanediol, Saxagliptin Hydrochloride interacts with Hemp Seed Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Oleic AcidAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oleic acid might increase the effects of antidiabetes drugs.
Read the full Oleic Acid + Dapagliflozin Propanediol, Saxagliptin Hydrochloride interactionDapagliflozin, Metformin Hydrochloride, Saxagliptin HydrochlorideQternmet XR
How Dapagliflozin, Metformin Hydrochloride, Saxagliptin Hydrochloride interacts with Hemp Seed Oil 1000 mg — through 2 ingredients. Tap an ingredient for the detail:
Oleic AcidAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oleic acid might increase the effects of antidiabetes drugs.
Read the full Oleic Acid + Dapagliflozin, Metformin Hydrochloride, Saxagliptin Hydrochloride interactionHemp Seed OilCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Seed Oil + Dapagliflozin, Metformin Hydrochloride, Saxagliptin Hydrochloride interactionDasiglucagon HydrochlorideZegalogue
How Dasiglucagon Hydrochloride interacts with Hemp Seed Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Oleic AcidAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oleic acid might increase the effects of antidiabetes drugs.
Read the full Oleic Acid + Dasiglucagon Hydrochloride interactionDesogestrel, Ethinyl EstradiolDesogen, Marvelon, Marvelon 21, Marvelon 28, Mircette, Ortho-Cept +2 more
How Desogestrel, Ethinyl Estradiol interacts with Hemp Seed Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Seed OilCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Seed Oil + Desogestrel, Ethinyl Estradiol interactionDrospirenone, EstetrolNextstellis
How Drospirenone, Estetrol interacts with Hemp Seed Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Seed OilCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Seed Oil + Drospirenone, Estetrol interactionDrospirenone, Ethinyl EstradiolAngeliq, Gianvi, Yasmin
How Drospirenone, Ethinyl Estradiol interacts with Hemp Seed Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Seed OilEstrogens, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Hemp Seed Oil + Drospirenone, Ethinyl Estradiol interactionDulaglutideTrulicity
How Dulaglutide interacts with Hemp Seed Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Oleic AcidAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oleic acid might increase the effects of antidiabetes drugs.
Read the full Oleic Acid + Dulaglutide interactionEmpagliflozinJardiance
How Empagliflozin interacts with Hemp Seed Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Oleic AcidAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oleic acid might increase the effects of antidiabetes drugs.
Read the full Oleic Acid + Empagliflozin interactionEmpagliflozin, Linagliptin, Metformin HydrochlorideTrijardy XR
How Empagliflozin, Linagliptin, Metformin Hydrochloride interacts with Hemp Seed Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Oleic AcidAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oleic acid might increase the effects of antidiabetes drugs.
Read the full Oleic Acid + Empagliflozin, Linagliptin, Metformin Hydrochloride interactionEmpagliflozin, MetforminSynjardy
How Empagliflozin, Metformin interacts with Hemp Seed Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Oleic AcidAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oleic acid might increase the effects of antidiabetes drugs.
Read the full Oleic Acid + Empagliflozin, Metformin interactionEmpagliflozin, Metformin HydrochlorideSynjardy XR
How Empagliflozin, Metformin Hydrochloride interacts with Hemp Seed Oil 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Oleic AcidAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oleic acid might increase the effects of antidiabetes drugs.
Read the full Oleic Acid + Empagliflozin, Metformin Hydrochloride interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Hemp Seed Oil 1000 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Hemp seed Oil
Estrogens
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
In an ovariectomized animal model, a diet containing hemp seed 1%, 2%, or 10% resulted in normalized plasma levels of 17-beta-estradiol. The mechanism of action for this effect is unclear.
Ace Inhibitors (Aceis)
Theoretically, consuming hemp seed protein isolate with ACE inhibitors might have additive effects and increase the risk of hypotension.
Hemp seed protein hydrolysate has shown ACE inhibitor-like effects in a hypertensive animal model. However, hempseed oil consumption does not seem to reduce blood pressure in humans. Until more is known, monitor blood pressure and potassium levels.
Anticoagulant/Antiplatelet Drugs
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
In animal research, hemp seed at 5% of the diet inhibits platelet aggregation in vitro. However, in human research, taking hemp seed oil 2 grams daily for 12 weeks does not inhibit the aggregation of platelets in vitro.
Antihypertensive Drugs
Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
In a hypertensive animal model, hemp seed protein hydrolysate reduced systolic blood pressure by a mechanism possibly involving the inhibition of renin and angiotensin converting enzyme (ACE) activities. However, there was no effect of hemp seed protein on blood pressure in normotensive animals. Furthermore, hempseed oil consumption does not seem to reduce blood pressure in humans.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that hemp induces CYP1A2 enzymes.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that hemp induces CYP3A4 enzymes.
Brand information
Manufacturer and brand details for Hemp Seed Oil 1000 mg, from the product label.
NusaPure
See all NusaPure products- Name
- Gmax Central LLC
- Street Address
- 4700 Millenia Boulevard, Suite 175 PMB 92909
- City
- Orlando
- State
- FL
- ZipCode
- 32839
Hemp Seed Oil 1000 mg by NusaPure: Common Questions
Does Hemp Seed Oil 1000 mg by NusaPure interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will this help my cholesterol or heart health?
Can I take this while I'm pregnant or breastfeeding?
What exactly is in this product?
Are there any side effects I should know about?
Does this product interact with a lot of medications?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Hemp Seed Oil 1000 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Hemp Seed Oil 1000 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Hemp
Interacts with 938 drugsHemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for most people as part of the diet. While...
Read the full Hemp monograph → Herb & supplement monographOleic Acid
Interacts with 86 drugsOleic acid is a heart-healthy monounsaturated fat found mainly in olive oil, canola oil, avocados, and nuts. As part of a Mediterranean-style diet, it is widely viewed as a healthier replace...
Read the full Oleic Acid monograph →Sources & How We Checked
Hemp Seed Oil 1000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 31 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Hemp 12 references
- Kaul N, Kreml R, Austria JA, et al. A comparison of fish oil, flaxseed oil and hempseed oil supplementation on selected parameters of cardiovascular health in healthy volunteers. J Am Coll Nutr 2008;27:51-8. PubMed
- Saberivand A, Karimi I, Becker LA, et al. The effects of Cannabis sativa L. seed (hempseed) in the ovariectomized rat model of menopause. Methods Find Exp Clin Pharmacol. 2010;32(7):467-73. PubMed
- Girgih AT, Alashi A, He R, Malomo S, Aluko RE. Preventive and treatment effects of a hemp seed (Cannabis sativa L.) meal protein hydrolysate against high blood pressure in spontaneously hypertensive rats. Eur J Nutr. 2014;53(5):1237-46. PubMed
- Richard MN, Ganguly R, Steigerwald SN, Al-Khalifa A, Pierce GN. Dietary hempseed reduces platelet aggregation. J Thromb Haemost. 2007;5(2):424-5. PubMed
- Stadtmauer G, Beyer K, Bardina L, Sicherer SH. Anaphylaxis to ingestion of hempseed (Cannabis sativa). J Allergy Clin Immunol. 2003;112(1):216-7. PubMed
- Del Bo' C, Deon V, Abello F, et al. Eight-week hempseed oil intervention improves the fatty acid composition of erythrocyte phospholipids and the omega-3 index, but does not affect the lipid profile in children and adolescents with primary hyperlipidemia. PubMed
- Alkhammash S, Tsui H, Thomson DMP. Cannabis and hemp seed allergy. J Allergy Clin Immunol Pract. 2019;7(7):2429-2430.e1. PubMed
- Stokes JR, Hartel R, Ford LB, Casale TB. Cannabis (hemp) positive skin tests and respiratory symptoms. Ann Allergy Asthma Immunol. 2000;85(3):238-40. PubMed
- Déléaval M, Burri H, Bakelants E. Harmless herbs? A case report of acquired long QT syndrome and torsades de pointes in a patient taking herbal supplements. HeartRhythm Case Rep 2022;8(5):309-12. PubMed
- Singh M, Sehgal M, Yacoub M, et al. Severe liver dysfunction in a toddler receiving nonprescription phytocannabinoid. J Am Pharm Assoc (2003) 2022;62(4):1438-1440. PubMed
- Clark E, Nilsson U, Samaran Q, Raison-Peyron N. Allergic contact dermatitis from Cannabis sativa (hemp) seed oil. Contact Dermatitis 2022;87(3):292-293.
- Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
Oleic Acid 19 references
- Madigan C, Ryan M, Owens D, et al. Dietary unsaturated fatty acids in type 2 diabetes: higher levels of postprandial lipoprotein on a linoleic acid-rich sunflower oil diet compared with an oleic acid-rich olive oil diet. Diabetes Care 2000;23:1472-7. PubMed
- Gillingham, L. G., Gustafson, J. A., Han, S. Y., Jassal, D. S., and Jones, P. J. High-oleic rapeseed (canola) and flaxseed oils modulate serum lipids and inflammatory biomarkers in hypercholesterolaemic subjects. Br J Nutr 2011;105(3):417-427. PubMed
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