Immune Protect with Paractin Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Immune Protect with Paractin against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Immune Protect with Paractin is a dietary supplement by Life Extension with 4 active ingredients. Its ingredients are commonly taken for high cholesterol, heart health, immune support.Based on those ingredients, 578 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Paractin (Bioactive 14-Neo-Andro Compound) Andrographis extract, Wellmune, Vitamin C. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Immune Protect with Paractin by Life Extension
Ask about any prescription or over-the-counter medication and we check it for interactions with Immune Protect with Paractin by Life Extension — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Immune Protect with Paractin by Life Extension
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Immune Protect with Paractin contains four active ingredients. Wellmune is a beta-glucan—a type of fiber from yeast that's thought to support immune function.
Camu-camu extract comes from a South American fruit and is included for its nutrient profile. Vitamin C is a well-known antioxidant involved in immune health and collagen formation.
Paractin is an andrographis extract, a plant used traditionally to support immunity and inflammation response. The capsule also contains inactive ingredients—microcrystalline cellulose, vegetable cellulose, maltodextrin, silica, and stearic acid—which are fillers and binders that hold the formula together.
Does it work?
Moderate evidence
Beta-glucans (Wellmune) are rated likely effective for dyslipidemia (abnormal cholesterol) and coronary heart disease. Vitamin C is rated effective for vitamin C deficiency, and possibly effective for anemia of chronic disease, atrial fibrillation, cataracts, and exercise-induced respiratory infections.
Andrographis (Paractin) is rated possibly effective for tonsillopharyngitis (sore throat), ulcerative colitis, and osteoarthritis. We hold no effectiveness data for camu-camu extract in our monographs.
How safe is it?
Well-documented data
Beta-glucans from food are generally well tolerated, though concentrated supplement doses lack strong long-term safety data—use caution. Vitamin C is generally safe at normal doses but can cause abdominal cramps, heartburn, diarrhea, and nausea at doses above 2 grams daily; it may also increase kidney stone risk in people prone to them.
Andrographis is often well tolerated short-term, but long-term safety is not well established. It's most likely to cause nausea, diarrhea, headache, rash, and altered taste, especially at higher doses or beyond 14 days.
Rare serious effects include severe allergic reactions. For pregnancy: vitamin C in normal amounts is likely safe, but avoid high-dose supplements.
Camu-camu, andrographis, and beta-glucans should be avoided in pregnancy—there isn't enough safety data. For breastfeeding: there's little research on any of these ingredients, so caution is advised or they should be avoided.
Meds to double-check
Moderate interaction found
Check with your pharmacist before using this product if you take blood thinners or antiplatelet drugs (risk of increased bleeding), blood pressure medications (risk of low blood pressure), chemotherapy drugs, immunosuppressants, warfarin, oral contraceptives or hormone replacement therapy, or any pain relievers like celecoxib or etoricoxib. These interactions are rated Moderate to Minor severity.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
If you're looking to support immunity and don't take blood thinners, blood pressure medications, immunosuppressants, chemotherapy, or birth control, this product may be reasonable to consider. However, the ingredients lack strong long-term safety data as concentrated supplements, and andrographis should be avoided in pregnancy and breastfeeding.
Always check your exact medications with your pharmacist before starting, especially if you're on any prescription drugs.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 4 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Immune Protect with Paractin, straight from the product label.
| Brand | Life Extension |
|---|---|
| Barcode (UPC) | 737870955030 |
| Net contents | 30 Vegetarian Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Aug 23, 2020 |
| DSLD ID | 231708 |
| Product type | Botanical With Nutrients |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Immune Protect with Paractin by Life Extension, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Wellmune | 100 mg | -- |
| Camu-Camu extract | 250 mg | -- |
| Vitamin C | 50 mg | 56% |
| Paractin (Bioactive 14-Neo-Andro Compound) Andrographis extract | 25 mg | -- |
Other ingredients: Vegetable Cellulose, Microcrystalline Cellulose, Maltodextrin, Silica, Stearic Acid
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Read the entire label and follow the directions carefully prior to use. Directions: Take one (1) capsule daily on an empty stomach, or as recommended by a healthcare practitioner. Increase dose up to six (6) capsules daily if needed.
Storage
Store tightly closed in a cool, dry place.
Precautions
Warnings: Keep out of reach of children.
Do not exceed recommended dose. Do not purchase if outer seal is broken or damaged.
When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
To report a serious adverse event or obtain product information, contact 1-866-280-2852.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Brand IP Statement(s)
Paractin is a registered trademark of HP Ingredients. Wellmune is a registered trademark of Kerry Group.
Seals/Symbols
Non GMO LE Certified
Formulation
Non GMO LE Certified
Daily immune support
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Immune Protect with Paractin by Life Extension label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Immune Protect with Paractin by Life Extension
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Vegetarian Capsule(s) Dosage formCapsule Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Wellmune
Interacts with293 drugs
Beta-glucans are natural fibers found in oats, barley, mushrooms, and yeast. The strongest evidence supports the oat and barley types for modestly low...
Wellmune monograph & interactionsCamu-Camu extract
No knowninteractions
Camu camu is an Amazonian berry that is very high in vitamin C and plant antioxidants, which is why it is popular as an immune and antioxidant supplem...
Camu-Camu extract monograph & interactionsVitamin C
Interacts with207 drugs
Vitamin C (ascorbic acid) is an essential nutrient your body needs but cannot make, so you must get it from food or supplements. It's important for im...
Vitamin C monograph & interactionsParactin (Bioactive 14-Neo-Andro Compound) Andrographis extract
Interacts with413 drugs
Andrographis is a bitter Asian herb traditionally used for colds, flu, and infections, and some studies suggest it may ease cold symptoms and shorten...
Paractin (Bioactive 14-Neo-Andro Compound) Andrographis extract monograph & interactionsOther (inactive) ingredients: Vegetable Cellulose, Microcrystalline Cellulose, Maltodextrin, Silica, Stearic Acid. These complete the product’s ingredient list but are not active constituents.
Immune Protect with Paractin by Life Extension Drug Interactions
HelloPharmacist Interaction Report
Immune Protect with Paractin by Life Extension does interact with a number of medications.
Altogether, these interactions span 572 individual medications.
Read the full breakdown — every affected drug type, severity by severity
The most serious documented interaction is with beta-glucans (Wellmune) and blood pressure-lowering drugs (antihypertensives). Beta-glucans may lower blood pressure on their own, so combining them with blood pressure medications could theoretically increase your risk of low blood pressure.
The product also contains vitamin C, which at high doses can interfere with warfarin (a blood thinner)—it may reduce how well warfarin works by lowering its absorption.
Vitamin C in this product may also affect estrogen levels if you take oral contraceptives or hormone replacement therapy, and it can increase the absorption of aluminum from aluminum-containing compounds. There's also theoretical concern that vitamin C's antioxidant effects might reduce the activity of certain chemotherapy drugs.
The andrographis extract (Paractin) adds further considerations: it may increase bleeding risk with blood thinners and antiplatelet drugs, and it could theoretically interfere with drugs that suppress your immune system.
Beta-glucans and andrographis both raise theoretical concerns about immunosuppressants—drugs used after organ transplants or for certain autoimmune conditions. Andrographis may also affect blood sugar control with glipizide and interact with certain pain relievers like celecoxib and etoricoxib, though these are rated as minor concerns.
Before you start this product, use the checker below to search your exact medications—especially if you take blood thinners, blood pressure drugs, chemotherapy, birth control, or immunosuppressants.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Immune Protect with Paractin?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Immune Protect with Paractin interact with 578 drugs. Click any drug to see the details.
3 of the 4 ingredients in Immune Protect with Paractin interact with drugs. Each result below shows which ingredient is responsible. Paractin (Bioactive 14-Neo-Andro Compound) Andrographis extract Wellmune Vitamin C
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Immune Protect with Paractin — through 2 ingredients. Tap an ingredient for the detail:
WellmuneImmunosuppressants Moderate
Interaction Summary
Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Read the full Wellmune + 6-mercaptopurine interactionParactin (bioactive 14-neo-andro Compound) Andrographis ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.
Read the full Paractin (bioactive 14-neo-andro Compound) Andrographis Extract + 6-mercaptopurine interactionAbciximabReoPro
How Abciximab interacts with Immune Protect with Paractin — through 1 ingredient. Tap an ingredient for the detail:
Paractin (bioactive 14-neo-andro Compound) Andrographis ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Paractin (bioactive 14-neo-andro Compound) Andrographis Extract + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Immune Protect with Paractin — through 2 ingredients. Tap an ingredient for the detail:
Paractin (bioactive 14-neo-andro Compound) Andrographis ExtractAnticoagulant/antiplatelet Drugs, Immunosuppressants Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Paractin (bioactive 14-neo-andro Compound) Andrographis Extract + Abrocitinib interactionWellmuneImmunosuppressants Moderate
Interaction Summary
Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Read the full Wellmune + Abrocitinib interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Immune Protect with Paractin — through 2 ingredients. Tap an ingredient for the detail:
Paractin (bioactive 14-neo-andro Compound) Andrographis ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of hypotension when used with antihypertensive drugs.
Read the full Paractin (bioactive 14-neo-andro Compound) Andrographis Extract + Acebutolol interactionWellmuneAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Read the full Wellmune + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Immune Protect with Paractin — through 1 ingredient. Tap an ingredient for the detail:
Paractin (bioactive 14-neo-andro Compound) Andrographis ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Paractin (bioactive 14-neo-andro Compound) Andrographis Extract + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Immune Protect with Paractin — through 2 ingredients. Tap an ingredient for the detail:
Paractin (bioactive 14-neo-andro Compound) Andrographis ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Paractin (bioactive 14-neo-andro Compound) Andrographis Extract + Acetaminophen, Aspirin interactionVitamin CAcetaminophen (tylenol, Others), Aspirin Minor
Interaction Summary
High-dose vitamin C might slightly prolong the clearance of acetaminophen.
Read the full Vitamin C + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Immune Protect with Paractin — through 2 ingredients. Tap an ingredient for the detail:
Paractin (bioactive 14-neo-andro Compound) Andrographis ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Paractin (bioactive 14-neo-andro Compound) Andrographis Extract + Acetaminophen, Aspirin, Caffeine interactionVitamin CAcetaminophen (tylenol, Others), Aspirin Minor
Interaction Summary
High-dose vitamin C might slightly prolong the clearance of acetaminophen.
Read the full Vitamin C + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Immune Protect with Paractin — through 2 ingredients. Tap an ingredient for the detail:
Paractin (bioactive 14-neo-andro Compound) Andrographis ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Paractin (bioactive 14-neo-andro Compound) Andrographis Extract + Acetaminophen, Ibuprofen interactionVitamin CAcetaminophen (tylenol, Others) Minor
Interaction Summary
High-dose vitamin C might slightly prolong the clearance of acetaminophen.
Read the full Vitamin C + Acetaminophen, Ibuprofen interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Immune Protect with Paractin — through 2 ingredients. Tap an ingredient for the detail:
WellmuneAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Read the full Wellmune + Acetazolamide interactionParactin (bioactive 14-neo-andro Compound) Andrographis ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of hypotension when used with antihypertensive drugs.
Read the full Paractin (bioactive 14-neo-andro Compound) Andrographis Extract + Acetazolamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Immune Protect with Paractin — through 2 ingredients. Tap an ingredient for the detail:
Paractin (bioactive 14-neo-andro Compound) Andrographis ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Paractin (bioactive 14-neo-andro Compound) Andrographis Extract + Acetylsalicylic Acid interactionVitamin CAspirin Minor
Interaction Summary
Acidification of the urine by vitamin C might increase aspirin levels.
Read the full Vitamin C + Acetylsalicylic Acid interactionAdalimumabHumira
How Adalimumab interacts with Immune Protect with Paractin — through 2 ingredients. Tap an ingredient for the detail:
Paractin (bioactive 14-neo-andro Compound) Andrographis ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.
Read the full Paractin (bioactive 14-neo-andro Compound) Andrographis Extract + Adalimumab interactionWellmuneImmunosuppressants Moderate
Interaction Summary
Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Read the full Wellmune + Adalimumab interactionAdalimumab-adazHyrimoz
How Adalimumab-adaz interacts with Immune Protect with Paractin — through 2 ingredients. Tap an ingredient for the detail:
WellmuneImmunosuppressants Moderate
Interaction Summary
Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Read the full Wellmune + Adalimumab-adaz interactionParactin (bioactive 14-neo-andro Compound) Andrographis ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.
Read the full Paractin (bioactive 14-neo-andro Compound) Andrographis Extract + Adalimumab-adaz interactionAdalimumab-adbmCyltezo
How Adalimumab-adbm interacts with Immune Protect with Paractin — through 2 ingredients. Tap an ingredient for the detail:
Paractin (bioactive 14-neo-andro Compound) Andrographis ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.
Read the full Paractin (bioactive 14-neo-andro Compound) Andrographis Extract + Adalimumab-adbm interactionWellmuneImmunosuppressants Moderate
Interaction Summary
Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Read the full Wellmune + Adalimumab-adbm interactionAdalimumab-afzbAbrilada
How Adalimumab-afzb interacts with Immune Protect with Paractin — through 2 ingredients. Tap an ingredient for the detail:
WellmuneImmunosuppressants Moderate
Interaction Summary
Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Read the full Wellmune + Adalimumab-afzb interactionParactin (bioactive 14-neo-andro Compound) Andrographis ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.
Read the full Paractin (bioactive 14-neo-andro Compound) Andrographis Extract + Adalimumab-afzb interactionAdalimumab-attoAmjevita
How Adalimumab-atto interacts with Immune Protect with Paractin — through 2 ingredients. Tap an ingredient for the detail:
Paractin (bioactive 14-neo-andro Compound) Andrographis ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.
Read the full Paractin (bioactive 14-neo-andro Compound) Andrographis Extract + Adalimumab-atto interactionWellmuneImmunosuppressants Moderate
Interaction Summary
Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Read the full Wellmune + Adalimumab-atto interactionAdalimumab-bwwdHadlima
How Adalimumab-bwwd interacts with Immune Protect with Paractin — through 2 ingredients. Tap an ingredient for the detail:
WellmuneImmunosuppressants Moderate
Interaction Summary
Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Read the full Wellmune + Adalimumab-bwwd interactionParactin (bioactive 14-neo-andro Compound) Andrographis ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.
Read the full Paractin (bioactive 14-neo-andro Compound) Andrographis Extract + Adalimumab-bwwd interactionAdalimumab-fkjpHulio
How Adalimumab-fkjp interacts with Immune Protect with Paractin — through 2 ingredients. Tap an ingredient for the detail:
Paractin (bioactive 14-neo-andro Compound) Andrographis ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.
Read the full Paractin (bioactive 14-neo-andro Compound) Andrographis Extract + Adalimumab-fkjp interactionWellmuneImmunosuppressants Moderate
Interaction Summary
Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Read the full Wellmune + Adalimumab-fkjp interactionAlefaceptAmevive
How Alefacept interacts with Immune Protect with Paractin — through 2 ingredients. Tap an ingredient for the detail:
WellmuneImmunosuppressants Moderate
Interaction Summary
Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Read the full Wellmune + Alefacept interactionParactin (bioactive 14-neo-andro Compound) Andrographis ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.
Read the full Paractin (bioactive 14-neo-andro Compound) Andrographis Extract + Alefacept interactionAlemtuzumabCampath
How Alemtuzumab interacts with Immune Protect with Paractin — through 2 ingredients. Tap an ingredient for the detail:
Paractin (bioactive 14-neo-andro Compound) Andrographis ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.
Read the full Paractin (bioactive 14-neo-andro Compound) Andrographis Extract + Alemtuzumab interactionWellmuneImmunosuppressants Moderate
Interaction Summary
Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Read the full Wellmune + Alemtuzumab interactionAlginic Acid, Aluminum HydroxideRafton
How Alginic Acid, Aluminum Hydroxide interacts with Immune Protect with Paractin — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAluminum Moderate
Interaction Summary
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Read the full Vitamin C + Alginic Acid, Aluminum Hydroxide interactionAliskirenTekturna
How Aliskiren interacts with Immune Protect with Paractin — through 2 ingredients. Tap an ingredient for the detail:
WellmuneAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Read the full Wellmune + Aliskiren interactionParactin (bioactive 14-neo-andro Compound) Andrographis ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of hypotension when used with antihypertensive drugs.
Read the full Paractin (bioactive 14-neo-andro Compound) Andrographis Extract + Aliskiren interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Immune Protect with Paractin — through 1 ingredient. Tap an ingredient for the detail:
Paractin (bioactive 14-neo-andro Compound) Andrographis ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Paractin (bioactive 14-neo-andro Compound) Andrographis Extract + Alteplase, Tpa interactionAltretamineHexalen
How Altretamine interacts with Immune Protect with Paractin — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAlkylating Agents Moderate
Interaction Summary
Theoretically, antioxidant effects of vitamin C might reduce the effectiveness of alkylating agents.
Read the full Vitamin C + Altretamine interactionAluminum Acetate, Benzethonium ChlorideBuro-Sol Otic Solution
How Aluminum Acetate, Benzethonium Chloride interacts with Immune Protect with Paractin — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAluminum Moderate
Interaction Summary
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Read the full Vitamin C + Aluminum Acetate, Benzethonium Chloride interactionAluminum ChlorideAluminum Chloride, Anhydrol Forte, Driclor, Drysol
How Aluminum Chloride interacts with Immune Protect with Paractin — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAluminum Moderate
Interaction Summary
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Read the full Vitamin C + Aluminum Chloride interactionAluminum HydroxideAlu-Cap, Amphojel, Gaviscon
How Aluminum Hydroxide interacts with Immune Protect with Paractin — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAluminum Moderate
Interaction Summary
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Read the full Vitamin C + Aluminum Hydroxide interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Immune Protect with Paractin — through 2 ingredients. Tap an ingredient for the detail:
Vitamin CAspirin, Aluminum Moderate
Interaction Summary
Acidification of the urine by vitamin C might increase aspirin levels.
Read the full Vitamin C + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionParactin (bioactive 14-neo-andro Compound) Andrographis ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Paractin (bioactive 14-neo-andro Compound) Andrographis Extract + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Immune Protect with Paractin — through 2 ingredients. Tap an ingredient for the detail:
Paractin (bioactive 14-neo-andro Compound) Andrographis ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Paractin (bioactive 14-neo-andro Compound) Andrographis Extract + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionVitamin CAspirin, Aluminum Moderate
Interaction Summary
Acidification of the urine by vitamin C might increase aspirin levels.
Read the full Vitamin C + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAluminum Hydroxide, Magnesium Hydroxide (otc Drug)Maalox, Mucogel
How Aluminum Hydroxide, Magnesium Hydroxide (otc Drug) interacts with Immune Protect with Paractin — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAluminum Moderate
Interaction Summary
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Read the full Vitamin C + Aluminum Hydroxide, Magnesium Hydroxide (otc Drug) interactionAluminum Hydroxide, Magnesium Hydroxide, Simethicone (otc Drug)Mylanta
How Aluminum Hydroxide, Magnesium Hydroxide, Simethicone (otc Drug) interacts with Immune Protect with Paractin — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAluminum Moderate
Interaction Summary
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Read the full Vitamin C + Aluminum Hydroxide, Magnesium Hydroxide, Simethicone (otc Drug) interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Immune Protect with Paractin with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Paractin (Bioactive 14-Neo-Andro Compound) Andrographis extract
Anticoagulant/Antiplatelet Drugs
Theoretically, andrographis might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Animal and laboratory studies suggest that andrographis has antiplatelet effects.
Antihypertensive Drugs
Theoretically, andrographis might increase the risk of hypotension when used with antihypertensive drugs.
Animal research suggests that andrographis has hypotensive effects.
Immunosuppressants
Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.
Laboratory research suggests that andrographolide has immunostimulant activity.
Celecoxib (Celebrex)
Theoretically, andrographis extract might increase the maximum concentration and time to peak concentration of celecoxib. The clinical significance of these changes is unclear.
Animal research suggests that andrographis extract taken orally increases the maximum concentration and time to peak concentration of celecoxib but does not appear to impact the area under the curve.
Etoricoxib (Arcoxia)
Theoretically, andrographis might decrease the absorption of etoricoxib, although the clinical significance is unclear.
Animal research shows that andrographis extract, or the constituent andrographolide, taken orally with etoricoxib decreases the bioavailability of etoricoxib. However, this reduced bioavailability is not correlated with a reduction in the anti-inflammatory effects of etoricoxib in arthritic mice models. The clinical significance of this interaction is unclear.
Glipizide (Glucotrol)
Theoretically, andrographis extract might increase the maximum concentration and area under the curve of glipizide; however, opposite effects are seen with the constituent, andrographolide. The clinical significance of this interaction is unclear.
Animal research suggests that andrographis extract taken orally with glipizide in diabetes-induced rats increases the maximum concentration and area under the curve of glipizide. However, the opposite effect is seen with the constituent, andrographolide, in which the maximum concentration and area under the curve are decreased when taken with glipizide.
Wellmune
Antihypertensive Drugs
Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Clinical research shows that taking beta-glucans may reduce systolic and diastolic blood pressure in some hypertensive individuals.
Immunosuppressants
Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Some clinical research shows that beta-glucans have immunostimulant effects.
Vitamin C
Alkylating Agents
Theoretically, antioxidant effects of vitamin C might reduce the effectiveness of alkylating agents.
The use of antioxidants like vitamin C during chemotherapy is controversial. There is concern that antioxidants could reduce the activity of chemotherapy drugs that generate free radicals, such as cyclophosphamide, chlorambucil, carmustine, busulfan, and thiotepa. In contrast, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that could interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effect, if any, antioxidants such as vitamin C have on chemotherapy.
Aluminum
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Research in animals and humans shows that vitamin C increases aluminum absorption, theoretically by chelating aluminum and keeping it in solution where it is available for absorption. In people with normal renal function, urinary excretion of aluminum will likely increase, making aluminum retention and toxicity unlikely. Patients with renal failure who take aluminum-containing compounds such as phosphate binders should avoid vitamin C supplements in doses above the recommended dietary allowances.
Antitumor Antibiotics
Theoretically, the antioxidant effects of vitamin C might reduce the effectiveness of antitumor antibiotics.
The use of antioxidants like vitamin C during chemotherapy is controversial. There is concern that antioxidants could reduce the activity of chemotherapy drugs which generate free radicals, such as doxorubicin. In contrast, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that could interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effects, if any, antioxidants such as vitamin C have on chemotherapy.
Estrogens
Vitamin C might increase blood levels of estrogens.
Increases in plasma estrogen levels of up to 55% occur under some circumstances when vitamin C is taken concurrently with oral contraceptives or hormone replacement therapy, including topical products. It is suggested that vitamin C prevents oxidation of estrogen in the tissues, regenerates oxidized estrogen, and reduces sulfate conjugation of estrogen in the gut wall. When tissue levels of vitamin C are high, these processes are already maximized and supplemental vitamin C does not have any effect on estrogen levels. Increases in plasma estrogen levels may occur when patients who are deficient in vitamin C take supplements. Monitor these patients for estrogen-related side effects.
Fluphenazine (Prolixin)
Theoretically, vitamin C might decrease levels of fluphenazine.
In one patient there was a clinically significant decrease in fluphenazine levels when vitamin C (500 mg twice daily) was started. The mechanism is not known, and there is no further data to confirm this interaction.
Indinavir (Crixivan)
Vitamin C can modestly reduce indinavir levels.
One pharmacokinetic study shows that taking vitamin C 1 gram orally once daily along with indinavir 800 mg orally three times daily reduces the area under the concentration-time curve of indinavir by 14%. The mechanism of this interaction is unknown, but it is unlikely to be clinically significant in most patients. The effect of higher doses of vitamin C on indinavir levels is unknown.
Levothyroxine (Synthroid, Others)
Vitamin C can increase levothyroxine absorption.
Two clinical studies in adults with poorly controlled hypothyroidism show that swallowing levothyroxine with a glass of water containing vitamin C 500-1000 mg in solution reduces thyroid stimulating hormone (TSH) levels and increases thyroxine (T4) levels when compared with taking levothyroxine alone. This suggests that vitamin C increases the oral absorption of levothyroxine, possibly due to a reduction in pH.
Warfarin (Coumadin)
High-dose vitamin C might reduce the levels and effectiveness of warfarin.
Vitamin C in high doses may cause diarrhea and possibly reduce warfarin absorption. There are reports of two people who took up to 16 grams daily of vitamin C and had a reduction in prothrombin time. Lower doses of 5-10 grams daily can also reduce warfarin absorption. In many cases, this does not seem to be clinically significant. However, a case of warfarin resistance has been reported for a patient who took vitamin C 500 mg twice daily. Cessation of vitamin C supplementation resulted in a rapid increase in international normalized ratio (INR). Tell patients taking warfarin to avoid taking vitamin C in excessively high doses (greater than 10 grams daily). Lower doses may be safe, but the anticoagulation activity of warfarin should be monitored. Patients who are stabilized on warfarin while taking vitamin C should avoid adjusting vitamin C dosage to prevent the possibility of warfarin resistance.
Acetaminophen (Tylenol, Others)
High-dose vitamin C might slightly prolong the clearance of acetaminophen.
A small pharmacokinetic study in healthy volunteers shows that taking high-dose vitamin C (3 grams) 1.5 hours after taking acetaminophen 1 gram slightly increases the apparent half-life of acetaminophen from around 2.3 hours to 3.1 hours. Ascorbic acid competitively inhibits sulfate conjugation of acetaminophen. However, to compensate, elimination of acetaminophen glucuronide and unconjugated acetaminophen increases. This effect is not likely to be clinically significant.
Aspirin
Acidification of the urine by vitamin C might increase aspirin levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams daily of vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction is not clinically significant.
Choline Magnesium Trisalicylate (Trilisate)
Acidification of the urine by vitamin C might increase choline magnesium trisalicylate levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams daily of vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction probably is not clinically significant.
Niacin
Vitamin C might decrease the beneficial effects of niacin on high-density lipoprotein (HDL) cholesterol levels.
A combination of niacin and simvastatin (Zocor) effectively raises HDL cholesterol levels in patients with coronary disease and low HDL levels. Clinical research shows that taking a combination of antioxidants (vitamin C, vitamin E, beta-carotene, and selenium) along with niacin and simvastatin (Zocor) attenuates this rise in HDL, specifically the HDL-2 and apolipoprotein A1 fractions, by more than 50% in patients with coronary disease. It is not known whether this adverse effect is due to a single antioxidant such as vitamin C, or to the combination. It also is not known whether it will occur in other patient populations.
Salsalate (Disalcid)
Acidification of the urine by vitamin C might increase salsalate levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams/day vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction probably is not clinically significant.
Brand information
Manufacturer and brand details for Immune Protect with Paractin, from the product label.
Life Extension
See all Life Extension products- Name
- Quality Supplements and Vitamins, Inc.
- City
- Ft. Lauderdale
- State
- FL
- ZipCode
- 33309
- Phone Number
- 1-866-280-2852
- Web Address
- LifeExtension.com
Immune Protect with Paractin by Life Extension: Common Questions
Does Immune Protect with Paractin by Life Extension interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
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Can high-dose vitamin C in this product cause side effects?
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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The Full Monographs Behind Immune Protect with Paractin’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Beta-glucans
Interacts with 293 drugsBeta-glucans are natural fibers found in oats, barley, mushrooms, and yeast. The strongest evidence supports the oat and barley types for modestly lowering cholesterol and blood sugar, while...
Read the full Beta-glucans monograph → Herb & supplement monographCamu Camu
Camu camu is an Amazonian berry that is very high in vitamin C and plant antioxidants, which is why it is popular as an immune and antioxidant supplement. Human research is still limited, so...
Read the full Camu Camu monograph → Herb & supplement monographVitamin C
Interacts with 207 drugsVitamin C (ascorbic acid) is an essential nutrient your body needs but cannot make, so you must get it from food or supplements. It's important for immune function, collagen, and acts as an...
Read the full Vitamin C monograph → Herb & supplement monographAndrographis
Interacts with 413 drugsAndrographis is a bitter Asian herb traditionally used for colds, flu, and infections, and some studies suggest it may ease cold symptoms and shorten how long they last. The evidence is limi...
Read the full Andrographis monograph →Sources & How We Checked
Immune Protect with Paractin's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 90 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Beta-glucans 11 references
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- Keenan, J. M., Pins, J. J., Frazel, C., Moran, A., and Turnquist, L. Oat ingestion reduces systolic and diastolic blood pressure in patients with mild or borderline hypertension: a pilot trial. J.Fam.Pract. 2002;51(4):369.
- Maki, K. C., Galant, R., Samuel, P., Tesser, J., Witchger, M. S., Ribaya-Mercado, J. D., Blumberg, J. B., and Geohas, J. Effects of consuming foods containing oat beta-glucan on blood pressure, carbohydrate metabolism and biomarkers of oxidative stress i
- Bergendiova, K., Tibenska, E., and Majtan, J. Pleuran (beta-glucan from Pleurotus ostreatus) supplementation, cellular immune response and respiratory tract infections in athletes. Eur.J.Appl.Physiol 2011;111(9):2033-2040.
- Talbott S, Talbott J. Effect of beta 1,3/1,6 glucan on respiratory tract infection symptoms and mood state in marathon athletes. J Sports Sci Med 2009;8(4):509-515.
- Feldman S, Schwartz HI Kalman DS Mayers A Kohrman HM Clemens R Krieger DR. Randomized phase II clinical trials of Wellmune WGP® for immune support during cold and flu season. The Journal of Applied Research 2009;9(1-2):30-42.
- McFarlin BK, Carpenter KC, Davidson T, McFarlin MA. Baker's yeast beta glucan supplementation increases salivary IgA and decreases cold/flu symptomatic days after intense exercise. J Diet Suppl. 2013;10(3):171-83. PubMed
- Jesenak M, Urbancek S, Majtan J, Banovcin P, Hercogova J. ß-Glucan-based cream (containing pleuran isolated from pleurotus ostreatus) in supportive treatment of mild-to-moderate atopic dermatitis. J Dermatolog Treat 2016;27(4):351-4.
- Mah E, Kaden VN, Kelley KM, Liska DJ. Beverage containing dispersible yeast ß-glucan decreases cold/flu symptomatic days after intense exercise: a randomized controlled trial. J Diet Suppl 2020;17(2):200-10. PubMed
- Zhong K, Liu Z, Lu Y, Xu X. Effects of yeast ß-glucans for the prevention and treatment of upper respiratory tract infection in healthy subjects: a systematic review and meta-analysis. Eur J Nutr. 2021. PubMed
- Cardenas FI, Mauguen A, Cheung IY, et al. Phase I trial of oral yeast-derived ß-glucan to enhance anti-GD2 immunotherapy of resistant high-risk neuroblastoma. Cancers (Basel) 2021;13(24):6265. PubMed
Camu Camu 2 references
Vitamin C 51 references
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- Domingo JL, Gomez M, Llobet JM, Corbella J. Influence of some dietary constituents on aluminum absorption and retention in rats. Kidney Int 1991;39:598-601. PubMed
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- Vihtamaki T, Parantainen J, Koivisto AM, et al. Oral ascorbic acid increases plasma oestradiol during postmenopausal hormone replacement therapy. Maturitas 2002;42:129-35. PubMed
- Slain D, Amsden JR, Khakoo RA, et al. Effect of high-dose vitamin C on the steady-state pharmacokinetics of the protease inhibitor indinavir in healthy volunteers. Pharmacotherapy 2005;25:165-70. PubMed
- Cheung MC, Zhao XQ, Chait A, et al. Antioxidant supplements block the response of HDL to simvastatin-niacin therapy in patients with coronary artery disease and low HDL. Arterioscler Thromb Vasc Biol 2001;21:1320-6. PubMed
- Feetam CL, Leach RH, Meynell MJ. Lack of a clinically important interaction between warfarin and ascorbic acid. Toxicol Appl Pharmacol 1975;31:544-7. PubMed
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- Ward NC, Hodgson JM, Croft KD, et al. The combination of vitamin C and grape-seed polyphenols increases blood pressure: a randomized, double-blind, placebo-controlled trial. J Hypertens 2005;23:427-34.. PubMed
- Prasad KN. Rationale for using high-dose multiple dietary antioxidants as an adjunct to radiation therapy and chemotherapy. J Nutr 2004;134:3182S-3S. PubMed
- Conklin KA. Cancer chemotherapy and antioxidants. J Nutr 2004;134:3201S-3204S. PubMed
- Fairweather-Tait S, Hickson K, McGaw B, et al. Orange juice enhances aluminium absorption from antacid preparation. Eur J Clin Nutr. 1994;48(1):71-3.
- Gruenwald, J., Graubaum, H. J., Busch, R., and Bentley, C. Safety and tolerance of ester-C compared with regular ascorbic acid. Adv.Ther. 2006;23(1):171-178.
- Rahimi, R., Nikfar, S., Rezaie, A., and Abdollahi, M. A meta-analysis on the efficacy and safety of combined vitamin C and E supplementation in preeclamptic women. Hypertens.Pregnancy. 2009;28(4):417-434. PubMed
- Einerson, B., Nathorn, C., Kitiyakara, C., Sirada, M., and Thamlikitkul, V. The efficacy of ascorbic acid in suboptimal responsive anemic hemodialysis patients receiving erythropoietin: a meta-analysis. J Med.Assoc.Thai. 2011;94 Suppl 1:S134-S146.
- Li, G., Li, L., Yu, C., and Chen, L. Effect of vitamins C and E supplementation on Helicobacter pylori eradication: a meta-analysis. Br.J Nutr 2011;106(11):1632-1637.
- Chen X, Shen L, Gu X, et al. High-dose supplementation with vitamin C--induced pediatric urolithiasis: the first case report in a child and literature review. Urology. 2014;84(4):922-4. PubMed
- Sattar A, Willman JE, Kolluri R. Possible warfarin resistance due to interaction with ascorbic acid: case report and literature review. Am J Health Syst Pharm. 2013;70(9):782-6. PubMed
- Yaich S, Chaabouni Y, Charfeddine K, et al. Secondary oxalosis due to excess vitamin C intake: a cause of graft loss in a renal transplant recipient. Saudi J Kidney Dis Transpl. 2014;25(1):113-6. PubMed
- Jalloh MA, Gregory PJ, Hein D, et al. Dietary supplement interactions with antiretrovirals: a systematic review. Int J STD AIDS. 2017 Jan;28(1):4-15. PubMed
- Rumbold A, Ota E, Nagata C, Shahrook S, Crowther CA. Vitamin C supplementation in pregnancy. Cochrane Database Syst Rev. 2015;(9):CD004072. PubMed
- Seo MS, Kim JK, Shim JY. High-dose vitamin C promotes regression of multiple pulmonary metastases originating from hepatocellular carcinoma. Yonsei Med J. 2015;56(5):1449-52. PubMed
- Skelin M, Lucijanic T, Amidzic Klaric D, et al. Factors Affecting Gastrointestinal Absorption of Levothyroxine: A Review. Clin Ther. 2017 Feb;39(2):378-403. PubMed
- Jiang K, Tang K, Liu H, Xu H, Ye Z, Chen Z. Ascorbic acid supplements and kidney stones incidence among men and women: a systematic review and meta-analysis. Urol J. 2019;16(2):115-120.
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- Maike A, Sturgill D, Gallan A. Oxalate Nephropathy in a Renal Transplant Recipient After Receiving High Dose Ascorbic Acid. Am J Med Sci 2021. PubMed
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Andrographis 26 references
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC