Interactions on record — worth a quick check against your medications. Based on 3 of 4 ingredients. Check your meds →
Dietary supplement

Immuno-DMG Ingredients & Drug Interactions

by DaVinci Laboratories

Tablet Or Pill Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Immuno-DMG is a dietary supplement by DaVinci Laboratories with 4 active ingredients. Its ingredients are commonly taken for immune support, blood sugar support in diabetes, high blood pressure.Based on those ingredients, 381 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Beta-1,3-Glucan, Maitake PD-Fraction powder, Larch tree (Larix laricina) Arabinogalactan powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Immuno-DMG by DaVinci Laboratories

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 4 of its 4 active ingredients.
  • “Maitake PD-Fraction powder” is listed as a grouped ingredient — the label gives one combined amount (17 mg) without saying how much of each component you get.

Immuno-DMG has four active ingredients designed to support immune function. Larch arabinogalactan is a fiber from the larch tree that may help with immune response.

Beta-glucans — a type of polysaccharide — and maitake PD-Fraction powder, derived from mushroom, are both included for their potential immune-supporting properties. N,N-Dimethylglycine HCl and D-Fraction round out the formula.

The tablets also contain inactive ingredients like microcrystalline cellulose, stearic acid, and silica to hold the tablet together.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: support proper immune system function.
  • We looked for evidence on: Allergic rhinitis (hay fever), Atopic dermatitis (eczema), Chemotherapy-induced leukopenia, Common cold, Coronavirus disease 2019 (COVID-19), Critical illness (trauma) — and 4 related terms.
  • The closest evidence on file: Larch Arabinogalactan is rated "Insufficient Reliable Evidence To Rate" for Common cold (Natural Medicines).
  • Also on file: Beta-glucans is rated "Insufficient Reliable Evidence To Rate" for Allergic rhinitis (hay fever), Inflammatory bowel disease (IBD), Atopic dermatitis (eczema), Exercise-induced respiratory infections, and more.

The evidence for this product's ingredients is mixed. Beta-glucans are rated Likely Effective for lowering cholesterol (dyslipidemia) and supporting heart health (coronary heart disease).

However, larch arabinogalactan has Insufficient Reliable Evidence To Rate for the common cold and cholesterol — meaning studies haven't established whether it works for these uses. We hold no effectiveness ratings for D-Fraction, N,N-Dimethylglycine HCl, or the maitake component in our data, so we can't say how they perform.

The evidence, ingredient by ingredient Maitake Mushroom Larch Arabinogalactan Beta-glucans

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Larch arabinogalactan and beta-glucans are generally well tolerated, though long-term safety data are limited for concentrated supplements. The most common side effect from larch arabinogalactan is bloating and flatulence — expected for a fiber.

Beta-glucans in food amounts are considered safe, but the safety profile of supplement doses is not well studied. One trial of children with neuroblastoma reported a single case of mild, temporary liver enzyme elevation after high-dose oral beta-glucans.

Topically applied beta-glucans cream caused mild, self-limiting skin reactions in some trial participants.

Side effects, ingredient by ingredient Maitake Mushroom Larch Arabinogalactan Beta-glucans

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Larch Arabinogalactan, Beta-glucans.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs.
  • For scale: 293 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications before taking this product if you take immunosuppressant drugs (like azathioprine, cyclosporine, mycophenolate, or tacrolimus) — larch arabinogalactan and beta-glucans may interfere with them. Also check if you take blood pressure medications, since beta-glucans might lower your blood pressure further and increase the risk of low blood pressure (hypotension).

We could not check D-Fraction or N,N-Dimethylglycine HCl for interactions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product may be worth considering if you're looking to support general immune health, and beta-glucans have solid evidence for cholesterol and heart health. However, if you take immunosuppressants (for an organ transplant or autoimmune condition) or blood pressure medication, talk to your pharmacist or doctor before starting — the ingredients may interfere with how these drugs work.

Anyone on medication should run their exact prescriptions through our checker first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Immuno-DMG, straight from the product label.

Brand DaVinci Laboratories
Barcode (UPC) 026664241894
Net contents 90 Tablet(s)
Market status On market
Date entered into DSLD Nov 22, 2023
DSLD ID 303880
Product type Other Combinations
Supplement form Tablet Or Pill
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Immuno-DMG by DaVinci Laboratories, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
90
UPC/BARCODE
026664241894
IngredientAmount% DV
D-Fraction5 mg--
N,N-Dimethylglycine HCl300 mg--
Maitake PD-Fraction powder17 mg--
Larch tree (Larix laricina) Arabinogalactan powder227 mg--
Beta-1,3-Glucan100 mg--

Other ingredients: Microcrystalline Cellulose, Stearic Acid, Vegetable Stearate, Croscarmellose Sodium, Silicon Dioxide, Hydroxypropylmethylcellulose, Titanium Dioxide, Polyethylene Glycol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Truth We pledge total truth in labeling. Our family of products contains only the purest and most potent ingredients. Guaranteed.

Formula

Immuno-DMG is an advanced nutritional supplement that combines 3 researched products: Gluconic DMG, Maitake D-Fraction (Maitake mushroom extract), and Larch Tree with Beta 1,3 glucans.

Formulation

The synergistic and powerful blend of well researched nutrients in Immuno-DMG was designed specifically to support proper Immune System Function.

Color of this product may vary due to color variations of the natural ingredients.

A Dietary Supplement to Support Immune System Function

Vegetarian / Gluten free

Vegetarian / Gluten free

Precautions

Warning: If pregnant, nursing or have an auto-immune disorder or are taking immune suppressant or blood thinning medications, do not take this product without first consulting your healthcare practitioner.

Caution: Discontinue use 2 weeks prior to surgery.

Keep out of reach of children.

To obtain product information or report a serious adverse event, call 1-800-325-1776. Not labeled for sale in California

Storage

Store in a cool, dry place.

Brand IP Statement(s)

Maitake PD-Fraction is a registered trademark of Mushroom Wisdom, Inc.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

A Dietary Supplement to Support Immune System Function

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take 1 tablet, 3 times daily, or as directed by your healthcare practitioner.

See for yourself

Immuno-DMG by DaVinci Laboratories label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Immuno-DMG by DaVinci Laboratories

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

N,N-Dimethylglycine HCl

300 mg per serving

Maitake PD-Fraction powder

Interacts with
260 drugs
17 mg per serving

Maitake is an edible mushroom long used as food and in traditional Japanese medicine, and it is being studied for possible immune, blood sugar, and bl...

Maitake PD-Fraction powder monograph & interactions
  • › D-Fraction
227 mg per serving

Larch arabinogalactan is a soluble fiber from larch trees that is mainly used as a prebiotic and for immune support. Early research is interesting but...

Larch tree (Larix laricina) Arabinogalactan powder monograph & interactions

Beta-1,3-Glucan

Interacts with
293 drugs
100 mg per serving Form: Baker's Yeast

Beta-glucans are natural fibers found in oats, barley, mushrooms, and yeast. The strongest evidence supports the oat and barley types for modestly low...

Beta-1,3-Glucan monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Stearic Acid, Vegetable Stearate, Croscarmellose Sodium, Silicon Dioxide, Hydroxypropylmethylcellulose, Titanium Dioxide, Polyethylene Glycol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Immuno-DMG by DaVinci Laboratories Drug Interactions

Want to check YOUR meds against Immuno-DMG?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
381Drugs
381 Moderate

Each ingredient & the kinds of drugs it affects

For each ingredient in Immuno-DMG with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Beta-1,3-Glucan2 drug types · 293 drugs

Antihypertensive Drugs

Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Clinical research shows that taking beta-glucans may reduce systolic and diastolic blood pressure in some hypertensive individuals.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Some clinical research shows that beta-glucans have immunostimulant effects.

Likelihood Possible Evidence D

Maitake PD-Fraction powder3 drug types · 260 drugs

Antidiabetes Drugs

Theoretically, combining maitake mushroom with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that taking maitake mushroom polysaccharide (MMP) can lower blood glucose levels in patients with types 2 diabetes.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, combining maitake mushroom with antihypertensive drugs might increase the risk of hypotension.
Animal research shows that maitake mushroom can lower blood pressure.

Likelihood Possible Evidence D
Warfarin (Coumadin)

There is limited evidence that maitake mushroom may increase the anticoagulant effects of warfarin.
In a case report, a patient previously stabilized on warfarin developed an elevated international normalized ratio (INR) of 5.1 after taking maitake mushroom (Grifron-Pro Maitake D-Fraction) 1 drop/kg daily in three divided doses for one week. The elevated INR resolved after holding warfarin for two days, then reducing the dose by 11%. It is thought that the beta-glucan constituent of maitake mushroom might cause warfarin dissociation from proteins, resulting in increased free warfarin levels and increased warfarin effects.

Likelihood Possible Evidence D

Larch tree (Larix laricina) Arabinogalactan powder1 drug type · 121 drugs

Immunosuppressants

Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects. Immunosuppressant drugs include azathioprine (Imuran), basiliximab (Simulect), cyclosporine (Neoral, Sandimmune), daclizumab (Zenapax), muromonab-CD3 (OKT3, Orthoclone OKT3), mycophenolate (CellCept), tacrolimus (FK506, Prograf), sirolimus (Rapamune), prednisone (Deltasone, Orasone), corticosteroids (glucocorticoids), and other drugs.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Immuno-DMG, from the product label.

DaVinci Laboratories

See all DaVinci Laboratories products
Name
DaVinci Laboratories a division of FoodScience LLC
Street Address
929 Harvest Lane
City
Williston
State
VT
ZipCode
05495
Phone Number
1-800-325-1776
Web Address
www.davincilabs.com
Pharmacist Counseling Corner

Immuno-DMG by DaVinci Laboratories: Common Questions

Does Immuno-DMG by DaVinci Laboratories interact with any medications?
Yes. Based on its ingredients, Immuno-DMG has a known interaction with 381 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Immuno-DMG contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does Immuno-DMG actually work for colds or the flu?
The evidence isn't established for larch arabinogalactan against colds — studies so far are not reliable enough to say it works. We don't have effectiveness ratings for the other immune-supporting ingredients either. If you're considering it for that reason, talk to your pharmacist about what the evidence shows.
What's the most common side effect?
Bloating and flatulence, since larch arabinogalactan is a fiber. Starting with a lower dose and drinking plenty of water may help. These effects are usually mild.
Can I take this if I'm pregnant or breastfeeding?
We don't have enough safety data for either pregnancy or breastfeeding. Talk with your doctor or pharmacist — they can weigh what we know and help you decide what's right for you.
Is this safe to use long-term?
Beta-glucans from food are well tolerated, but long-term safety data for concentrated supplements are limited. If you're planning to take this regularly, mention it to your healthcare provider, especially if you have any existing health conditions.
Will this interfere with my transplant medication?
Possibly — both larch arabinogalactan and beta-glucans may theoretically interfere with immunosuppressant drugs. Do not start this product without checking with your transplant team or pharmacist first.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Immuno-DMG is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Immuno-DMG label
Sources

Sources & How We Checked

Immuno-DMG's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 27 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Maitake Mushroom 8 references
  1. Kabir Y, Kimura S. Dietary mushrooms reduce blood pressure in spontaneously hypertensive rats (SHR). J Nutr Sci Vitaminol (Tokyo) 1989;35:91-4. PubMed
  2. Kabir Y, Yamaguchi M, Kimura S. Effect of shiitake (Lentinus edodes) and maitake (Grifola frondosa) mushrooms on blood pressure and plasma lipids of spontaneously hypertensive rats. J Nutr Sci Vitaminol (Tokyo) 1987;33:341-6. PubMed
  3. Konno S, Tortorelis DG, Fullerton SA, et al. A possible hypoglycaemic effect of maitake mushroom on Type 2 diabetic patients. Diabet Med 2001;18:1010. PubMed
  4. Chen JT, Tominaga K, Sato Y, et al. Maitake mushroom (Grifola frondosa) extract induces ovulation in patients with polycystic ovary syndrome: a possible monotherapy and a combination therapy after failure with first-line clomiphene citrate. J Altern Compl
  5. Hanselin MR, Vande Griend JP, Linnebur SA. INR elevation with maitake extract in combination with warfarin. Ann Pharmacother 2010;44:223-4. PubMed
  6. Talpur, N. A., Echard, B. W., Fan, A. Y., Jaffari, O., Bagchi, D., and Preuss, H. G. Antihypertensive and metabolic effects of whole Maitake mushroom powder and its fractions in two rat strains. Mol.Cell Biochem. 2002;237(1-2):129-136. PubMed
  7. Deng, G., Lin, H., Seidman, A., Fornier, M., D'Andrea, G., Wesa, K., Yeung, S., Cunningham-Rundles, S., Vickers, A. J., and Cassileth, B. A phase I/II trial of a polysaccharide extract from Grifola frondosa (Maitake mushroom) in breast cancer patients: i
  8. Wesa KM, Cunningham-Rundles S, Klimek VM, et al. Maitake mushroom extract in myelodysplastic syndromes (MDS): a phase II study. Cancer Immunol Immunother 2015;64(2):237-47. PubMed

See these in context on the Maitake Mushroom monograph →

Larch Arabinogalactan 8 references
  1. D'Adamo P. Larch arabinogalactan. J Naturopath Med 1996;6:33-7.
  2. Kelly GS. Larch arabinogalactan: Clinical relevance of a novel immune-enhancing polysaccharide. Alt Med Rev 1999;4:96-103.
  3. Marett R, Slavin JL. No long-term benefits of supplementation with arabinogalactan on serum lipids and glucose. J Am Diet Assoc 2004;104:636-9.
  4. Robinson RR, Feirtag J, Slavin JL. Effects of dietary arabinogalactan on gastrointestinal and blood parameters in healthy human subjects. J Am Coll Nutr 2001;20:279-85. PubMed
  5. Udani JK, Singh BB, Barrett ML, Singh VJ. Proprietary arabinogalactan extract increases antibody response to the pneumonia vaccine: a randomized, double-blind, placebo-controlled, pilot study in healthy volunteers. Nutr J 2010;9:32. PubMed
  6. Grube B, Stier H, Riede L, Gruenwald J. Tolerability of a proprietary larch arabinogalactan extract: a randomized, double-blind, placebo-controlled clinical trial in healthy subjects. Food Nutr Sci 2012;3:1533-8. DOI
  7. Dion C, Chappuis E, Ripoll C. Does larch arabinogalactan enhance immune function? A review of mechanistic and clinical trials. Nutr Metab (Lond) 2016;13:28. PubMed
  8. Riede L, Grube B, Gruenwald J. Larch arabinogalactan effects on reducing incidence of upper respiratory tract infections. Curr Med Res Opin 2013;29(3):251-8.

See these in context on the Larch Arabinogalactan monograph →

Beta-glucans 11 references
  1. Katz, D. L., Nawaz, H., Boukhalil, J., Giannamore, V., Chan, W., Ahmadi, R., and Sarrel, P. M. Acute effects of oats and vitamin E on endothelial responses to ingested fat. Am.J.Prev.Med. 2001;20(2):124-129. PubMed
  2. Keenan, J. M., Pins, J. J., Frazel, C., Moran, A., and Turnquist, L. Oat ingestion reduces systolic and diastolic blood pressure in patients with mild or borderline hypertension: a pilot trial. J.Fam.Pract. 2002;51(4):369.
  3. Maki, K. C., Galant, R., Samuel, P., Tesser, J., Witchger, M. S., Ribaya-Mercado, J. D., Blumberg, J. B., and Geohas, J. Effects of consuming foods containing oat beta-glucan on blood pressure, carbohydrate metabolism and biomarkers of oxidative stress i
  4. Bergendiova, K., Tibenska, E., and Majtan, J. Pleuran (beta-glucan from Pleurotus ostreatus) supplementation, cellular immune response and respiratory tract infections in athletes. Eur.J.Appl.Physiol 2011;111(9):2033-2040.
  5. Talbott S, Talbott J. Effect of beta 1,3/1,6 glucan on respiratory tract infection symptoms and mood state in marathon athletes. J Sports Sci Med 2009;8(4):509-515.
  6. Feldman S, Schwartz HI Kalman DS Mayers A Kohrman HM Clemens R Krieger DR. Randomized phase II clinical trials of Wellmune WGP® for immune support during cold and flu season. The Journal of Applied Research 2009;9(1-2):30-42.
  7. McFarlin BK, Carpenter KC, Davidson T, McFarlin MA. Baker's yeast beta glucan supplementation increases salivary IgA and decreases cold/flu symptomatic days after intense exercise. J Diet Suppl. 2013;10(3):171-83. PubMed
  8. Jesenak M, Urbancek S, Majtan J, Banovcin P, Hercogova J. ß-Glucan-based cream (containing pleuran isolated from pleurotus ostreatus) in supportive treatment of mild-to-moderate atopic dermatitis. J Dermatolog Treat 2016;27(4):351-4.
  9. Mah E, Kaden VN, Kelley KM, Liska DJ. Beverage containing dispersible yeast ß-glucan decreases cold/flu symptomatic days after intense exercise: a randomized controlled trial. J Diet Suppl 2020;17(2):200-10. PubMed
  10. Zhong K, Liu Z, Lu Y, Xu X. Effects of yeast ß-glucans for the prevention and treatment of upper respiratory tract infection in healthy subjects: a systematic review and meta-analysis. Eur J Nutr. 2021. PubMed
  11. Cardenas FI, Mauguen A, Cheung IY, et al. Phase I trial of oral yeast-derived ß-glucan to enhance anti-GD2 immunotherapy of resistant high-risk neuroblastoma. Cancers (Basel) 2021;13(24):6265. PubMed

See these in context on the Beta-glucans monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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