Interactions on record — worth a quick check against your medications. Based on 1 of 3 ingredients. Check your meds →
Dietary supplement

Intestinal Care Ingredients & Drug Interactions

by Ethical Nutrients

Intestinal Care label
See full label image
Powder Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Intestinal Care against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Intestinal Care is a dietary supplement by Ethical Nutrients with 3 active ingredients. Its ingredients are commonly taken for digestive health and balance, diarrhea (including antibiotic-related), vaginal yeast and bacterial infections.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lactobacillus acidophilus. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Intestinal Care by Ethical Nutrients

Ask about any prescription or over-the-counter medication and we check it for interactions with Intestinal Care by Ethical Nutrients — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Intestinal Care by Ethical Nutrients

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 3 active ingredients.

Ethical Nutrients Intestinal Care is a powder with 3 active ingredients: Lactobacillus acidophilus and Bifidobacterium infantis — both are beneficial bacteria (probiotics) that live in your gut — plus Globulin Protein Concentrate. The powder also contains fructooligosaccharides as an inactive ingredient (a type of fiber that can help feed beneficial bacteria).

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: intestinal health support.
  • We looked for evidence on: Antibiotic-associated diarrhea, Bacterial vaginosis, Clostridioides difficile infection, Colic, Constipation, Inflammatory bowel disease (IBD) — and 4 related terms.
  • The strongest evidence on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Antibiotic-associated diarrhea (Natural Medicines).
  • Also on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Bacterial vaginosis, Irritable bowel syndrome (IBS).
  • Also on file: Lactobacillus Acidophilus is rated "Insufficient Reliable Evidence To Rate" for Constipation, Inflammatory bowel disease (IBD), Lactose intolerance, Necrotizing enterocolitis (NEC).

Lactobacillus acidophilus is possibly effective for irritable bowel syndrome, antibiotic-associated diarrhea, Helicobacter pylori infection, and bacterial vaginosis. It's rated possibly ineffective for atopic disease, and we don't have enough reliable evidence to rate it for acute respiratory distress syndrome.

The effectiveness data we hold doesn't cover Bifidobacterium infantis or Globulin Protein Concentrate.

The evidence, ingredient by ingredient Lactobacillus Acidophilus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactobacillus acidophilus is generally well tolerated in healthy adults and children. Gastrointestinal side effects like bloating, flatulence, abdominal discomfort, and diarrhea can occur when combined with other probiotics, but these are uncommon.

In rare cases, L. acidophilus has been linked to serious infections in people with compromised immune systems or certain underlying conditions — most often through translocation (bacteria moving from their normal location in the body). A small number of trial participants using a probiotic blend that included L. acidophilus reported rash or itching, though it's unclear whether L. acidophilus alone was responsible.

For pregnancy, L. acidophilus is rated possibly safe. There's no lactation data on file for this ingredient.

Since safety data are limited, check with your doctor or pharmacist before use.

Side effects, ingredient by ingredient Lactobacillus Acidophilus

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Lactobacillus Acidophilus.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Antibiotic drugs are the main medication type to watch: taking them at the same time as this product may reduce how well the probiotics work. Space your doses apart and confirm the right timing with your doctor or pharmacist.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you have IBS, antibiotic-associated diarrhea, or bacterial vaginosis and want to try probiotics, this product may be worth considering — but timing matters if you're on antibiotics. Check your exact medications with your doctor or pharmacist before starting, especially if you're taking antibiotics, have a weakened immune system, or are pregnant or nursing.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 23, 2011.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Intestinal Care, straight from the product label.

Brand Ethical Nutrients
Barcode (UPC) 98129061057
Net contents 4 oz.; 113 Gram(s)
Market status On market
Date entered into DSLD Dec 23, 2011
DSLD ID 2939
Product type Other Combinations
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Intestinal Care by Ethical Nutrients, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.25 tsp
Maximum serving Sizes:
0.5 tsp
Servings per container
75
UPC/BARCODE
98129061057
IngredientAmount% DV
Calories5 {Calories}--
Total Carbohydrates1 g--
Lactobacillus acidophilus0 NP--
Bifidobacterium infantis0 NP--
Globulin Protein Concentrate560 mg--

Other ingredients: Fructooligosaccharides

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Intestinal Care is a truly exceptional probiotic supplement that supports intestinal health in three ways: 1. Highly viable strains of L. acidophilus and B. infantis. 2. FOS to feed and promote the growth of the friendly bacteria. 3. Immunoglobulin protein concentrate to promote the activity level of the intestinal immune system.

Patented Intestinal Care NCFM Acidophilus & Bifidobacteria Plus FOS & Immunoglobulins

FDA Disclaimer Statement

These statements have not been evalutaed by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Suggested/Recommended/Usage/Directions

Directions: Take 1/4 to 1/2 teaspoon mixed with four to six ounces of unchilled water two times daily with or without meals.

Storage

Notice: For maximum stability and viability, keep refrigerated. However, product may be stored at room temperature for up to a week or more without adversely affecting potency. This makes Intestinal Care an excellent choice for travelers.

Brand IP Statement(s)

Ethical Nutrients The Mark of Excellence

U.S. Patent Nos. 5,744,134; 6,241,983; 5,531,989; and 5,531,988

NCFM is a trademark of the North Carolina Dairy Foundation.

General Statements

4.5 billion organisms per serving guaranteed at date of expiration

Powder

FDA Statement of Identity

Dietary Supplement

General

PROD. # NT006 LNT006D

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Intestinal Care by Ethical Nutrients label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Intestinal Care label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Intestinal Care by Ethical Nutrients

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size0.25 tsp Dosage formPowder Servings per container75 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Lactobacillus acidophilus

Interacts with
182 drugs
0 NP per serving

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy p...

Lactobacillus acidophilus monograph & interactions

Bifidobacterium infantis

0 NP per serving

Globulin Protein Concentrate

560 mg per serving

Other (inactive) ingredients: Fructooligosaccharides. These complete the product’s ingredient list but are not active constituents.

Interaction report

Intestinal Care by Ethical Nutrients Drug Interactions

Want to check YOUR meds against Intestinal Care?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Lactobacillus acidophilus 182

Individual Drug Interactions

The ingredients in Intestinal Care interact with 182 drugs. Click any drug to see the details.

1 of the 3 ingredients in Intestinal Care interact with drugs. Each result below shows which ingredient is responsible. Lactobacillus acidophilus

Each ingredient & the kinds of drugs it affects

For each ingredient in Intestinal Care with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Lactobacillus acidophilus1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D
Lactobacillus acidophilus full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Intestinal Care, from the product label.

Ethical Nutrients

See all Ethical Nutrients products
Name
Ethical Nutrients, A Division of Metagenics, Inc.
City
San Clemente
State
CA
ZipCode
92673
Phone Number
1-800-877-1704
Pharmacist Counseling Corner

Intestinal Care by Ethical Nutrients: Common Questions

Does Intestinal Care by Ethical Nutrients interact with any medications?
Yes. Based on its ingredients, Intestinal Care has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Intestinal Care contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this work if I'm taking antibiotics?
The L. acidophilus in this product may not work as well if you take it at the same time as antibiotics — the antibiotics can kill the beneficial bacteria. You'll need to separate them by a few hours; your doctor or pharmacist can tell you the best timing for your specific antibiotic.
Can I take this while pregnant?
Lactobacillus acidophilus is rated possibly safe in pregnancy, but the data are limited. Talk with your doctor or pharmacist about whether it's right for you before starting.
What are the side effects?
Most people tolerate this product well. Gastrointestinal side effects like bloating, gas, abdominal pain, or diarrhea can happen when probiotics are combined, but they're uncommon. In rare cases, L. acidophilus has been linked to serious infections in people with very weak immune systems.
Is this powder safe for kids?
Lactobacillus acidophilus is generally well tolerated in healthy children. Still, check with your child's doctor or pharmacist before starting.
What does this product actually do?
The main active ingredient, L. acidophilus, is possibly effective for irritable bowel syndrome, antibiotic-associated diarrhea, Helicobacter pylori, and bacterial vaginosis. The other probiotic, Bifidobacterium infantis, may also support gut health, though we don't have specific effectiveness data on file for it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Intestinal Care is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Intestinal Care label
Go deeper

The Full Monographs Behind Intestinal Care’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lactobacillus Acidophilus

Interacts with 182 drugs

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...

Read the full Lactobacillus Acidophilus monograph →
Sources

Sources & How We Checked

Intestinal Care's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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