Interactions on record — worth a quick check against your medications. Based on 6 of 14 ingredients. Check your meds →
Dietary supplement

MegaFlora Kids Probiotic Ingredients & Drug Interactions

by MegaFood

MegaFlora Kids Probiotic label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking MegaFlora Kids Probiotic against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

MegaFlora Kids Probiotic is a dietary supplement by MegaFood with 14 active ingredients. Its ingredients are commonly taken for digestive health and balance, diarrhea (including antibiotic-related), vaginal yeast and bacterial infections.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lactobacillus acidophilus (SD-5212), Lactobacillus bulgaricus (SD-6833), Lactobacillus gasseri (SD-5585). Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against MegaFlora Kids Probiotic by MegaFood

Ask about any prescription or over-the-counter medication and we check it for interactions with MegaFlora Kids Probiotic by MegaFood — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of MegaFlora Kids Probiotic by MegaFood

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 14 active ingredients.
  • “Proprietary MegaFlora Blend:” is a proprietary blend — the label doesn't break down how much of each component you get.

MegaFood's MegaFlora Kids Probiotic contains 14 active ingredients — a blend of beneficial bacteria strains commonly used in kids' digestive health. The main players are Lactobacillus species (acidophilus, casei, plantarum, rhamnosus, salivarius, brevis, and gasseri) and Bifidobacterium species (lactis, longum, bifidum, and infantis), plus Lactococcus lactis and Streptococcus thermophilus.

These are all probiotics — live microorganisms meant to support digestive and immune function. The capsule also contains inactive ingredients including microcrystalline cellulose (a binding agent), hypromellose (for the capsule), L-leucine, and silicon dioxide.

These are excipients that help deliver the active bacteria.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: Promotes healthy immune and respiratory functions.
  • We looked for evidence on: Common cold, Exercise-induced respiratory infections, Asthma, Allergic rhinitis (hay fever), Upper respiratory tract infection, Respiratory health — and 2 related terms.
  • The closest evidence on file: Lactobacillus Acidophilus is rated "Insufficient Reliable Evidence To Rate" for Allergic rhinitis (hay fever) (Natural Medicines).
  • Also on file: Lactobacillus Acidophilus is rated "Insufficient Reliable Evidence To Rate" for Asthma.
  • Also on file: Bifidobacterium Bifidum is rated "Insufficient Reliable Evidence To Rate" for Allergic rhinitis (hay fever), Common cold, Exercise-induced respiratory infections.

The evidence for most of these probiotics is still emerging. Lactobacillus acidophilus is possibly effective for irritable bowel syndrome, Helicobacter pylori infection, antibiotic-associated diarrhea, and bacterial vaginosis.

Bifidobacterium bifidum is possibly effective for irritable bowel syndrome and respiratory tract infections. For most other conditions — allergies, asthma, anxiety, cognitive decline, and several others — the data we hold shows insufficient reliable evidence to rate effectiveness.

Talk with your child's doctor about what results you're hoping for and whether this product makes sense for your situation.

The evidence, ingredient by ingredient Lactobacillus Acidophilus Lactobacillus Delbrueckii Lactobacillus Gasseri Bifidobacterium Longum Bifidobacterium Bifidum Streptococcus Thermophilus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 6 of the 6 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 6 of 6.
  • General safety write-ups exist for 6 of 6.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactobacillus acidophilus and the Bifidobacterium species are generally well tolerated in healthy children and adults. However, the safety data are limited, and these products contain live bacteria, which carries a theoretical concern: in rare cases, especially in very ill, premature, or immune-compromised patients, these organisms have been reported to cause serious infections like bacteremia or sepsis.

Gastrointestinal side effects — bloating, flatulence, abdominal discomfort, diarrhea — are uncommon but can occur when you first start a probiotic. One ingredient, Lactobacillus bulgaricus, was associated with rash and itching in a clinical trial, though it's unclear whether the probiotic itself was responsible.

For pregnancy and lactation, Lactobacillus acidophilus, Bifidobacterium longum, Bifidobacterium bifidum, and Streptococcus thermophilus are rated possibly safe, but the data are limited. Talk with your doctor or pharmacist before using this product during pregnancy or while breastfeeding, especially since your child's own pregnancy or breastfeeding decisions may be far off.

Side effects, ingredient by ingredient Lactobacillus Acidophilus Lactobacillus Delbrueckii Lactobacillus Gasseri Bifidobacterium Longum Bifidobacterium Bifidum Streptococcus Thermophilus

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 5 of the 6 matched ingredients can interact with medications — Lactobacillus Acidophilus, Bifidobacterium Bifidum, Bifidobacterium Longum, Lactobacillus Delbrueckii, Lactobacillus Gasseri.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If your child takes antibiotic drugs, do not give this product at the same time — antibiotics will kill the live bacteria in it. Separate them by a few hours and confirm the timing with your child's doctor or pharmacist.

We could not check the interaction data for several of the bacterial strains in this blend, so mention all ingredients when you review it with your healthcare provider.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

MegaFlora Kids is a multi-strain probiotic that may help with certain digestive and immune concerns in healthy kids, though the evidence is mixed and still developing. If your child is on antibiotics, you'll need to space them apart from this product.

If your child is seriously ill, premature, or has a weakened immune system, check with their doctor first. Before starting, run your child's medications through the checker below and discuss the product with your pediatrician or pharmacist.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 6 of 14 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 19, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about MegaFlora Kids Probiotic, straight from the product label.

Brand MegaFood
Barcode (UPC) 051494102145
Net contents 30 Capsule(s)
Market status On market
Date entered into DSLD Nov 19, 2021
DSLD ID 256995
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for MegaFlora Kids Probiotic by MegaFood, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
30
UPC/BARCODE
051494102145
IngredientAmount% DV
Bifidobacterium lactis (SD-5219)0 NP--
Lactobacillus acidophilus (SD-5212)0 NP--
Lactobacillus casei (SD-5213)0 NP--
Lactobacillus plantarum (SD-5209)0 NP--
Lactobacillus rhamnosus (SD-5217)0 NP--
Lactobacillus salivarius (SD-5208)0 NP--
Lactobacillus brevis (SD-5214)0 NP--
Lactobacillus bulgaricus (SD-6833)0 NP--
Lactobacillus gasseri (SD-5585)0 NP--
Lactococcus lactis (SD-5584)0 NP--
Bifidobacterium longum (SD-5588)0 NP--
Bifidobacterium bifidum (SD-6575)0 NP--
Bifidobacterium infantis (SD-6720)0 NP--
Streptococcus thermophilus (SD-5207)0 NP--
Proprietary MegaFlora Blend:0 NP--

Other ingredients: Microcrystalline Cellulose, Hypromellose, L-Leucine, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols

To learn about our seals, please visit megafood.com/standards. Non GMO Project Verified nongmoproject.org V Certified Vegan Vegan.org NSF Certified Gluten-free Tested 125+ pesticides & herbicides Glyphosate Residue free detoxproject.org Certified B Corporation

Formulation

Non GMO project verified nongmoproject.org NSF Certified Gluten-free Tested free Pesticides & herbicides Soy free Dairy free

V Certified Vegan Vegan.org

Promotes healthy immune & respiratory functions

Potency guaranteed until expiration, when stored as recommended.

Formula

5 Billion live cultures 14 strains

MegaFood MegaFlora Kids Probiotic contains 5 billion active bacteria across 14 unique probiotic strains to help maintain the balance of healthy gut flora. This MegaFood product is made with a broad spectrum of health-supporting probiotic. Satisfaction guaranteed or your money back.

General Statements

30 servings

FDA Statement of Identity

Probiotic Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: 1 capsule per day with a meal and a beverage.

Once open, consume within three months.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Keep out of reach of children.

Storage

Keep refrigerated or frozen to maintain potency.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

MegaFlora Kids Probiotic by MegaFood label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

MegaFlora Kids Probiotic label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in MegaFlora Kids Probiotic by MegaFood

These are the 14 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary MegaFlora Blend:

0 NP per serving

Other (inactive) ingredients: Microcrystalline Cellulose, Hypromellose, L-Leucine, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

MegaFlora Kids Probiotic by MegaFood Drug Interactions

Want to check YOUR meds against MegaFlora Kids Probiotic?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Lactobacillus acidophilus (SD-5212) 182
Lactobacillus bulgaricus (SD-6833) 182
Lactobacillus gasseri (SD-5585) 182
Bifidobacterium longum (SD-5588) 182
Bifidobacterium bifidum (SD-6575) 182

Individual Drug Interactions

The ingredients in MegaFlora Kids Probiotic interact with 182 drugs. Click any drug to see the details.

5 of the 14 ingredients in MegaFlora Kids Probiotic interact with drugs. Each result below shows which ingredient is responsible. Lactobacillus acidophilus (SD-5212) Lactobacillus bulgaricus (SD-6833) Lactobacillus gasseri (SD-5585) Bifidobacterium longum (SD-5588) Bifidobacterium bifidum (SD-6575)

Each ingredient & the kinds of drugs it affects

For each ingredient in MegaFlora Kids Probiotic with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Lactobacillus acidophilus (SD-5212)1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D
Lactobacillus acidophilus (SD-5212) full monograph & interactions

Lactobacillus bulgaricus (SD-6833)1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L. delbrueckii.
Lactobacillus delbrueckii preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. delbrueckii preparations by at least two hours.

Likelihood Probable Evidence D
Lactobacillus bulgaricus (SD-6833) full monograph & interactions

Lactobacillus gasseri (SD-5585)1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus gasseri with antibiotic drugs might decrease the effectiveness of L. gasseri.
Lactobacillus gasseri preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. gasseri preparations by at least two hours.

Likelihood Probable Evidence D
Lactobacillus gasseri (SD-5585) full monograph & interactions

Bifidobacterium longum (SD-5588)1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B. longum.
Since B. longum preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. longum preparations by at least 2 hours.

Likelihood Probable Evidence D
Bifidobacterium longum (SD-5588) full monograph & interactions

Bifidobacterium bifidum (SD-6575)1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Bifidobacterium. bifidum with antibiotic drugs might decrease the effectiveness of B. bifidum.
Since B. bifidum preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. bifidum preparations by at least 2 hours.

Likelihood Probable Evidence D
Bifidobacterium bifidum (SD-6575) full monograph & interactions
The maker

Brand information

Manufacturer and brand details for MegaFlora Kids Probiotic, from the product label.

MegaFood

See all MegaFood products
Name
MegaFood
Street Address
PO Box 5244
City
Manchester
State
NH
ZipCode
03108
Phone Number
800.848.2542
Web Address
megafood.com
Pharmacist Counseling Corner

MegaFlora Kids Probiotic by MegaFood: Common Questions

Does MegaFlora Kids Probiotic by MegaFood interact with any medications?
Yes. Based on its ingredients, MegaFlora Kids Probiotic has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
MegaFlora Kids Probiotic contains 14 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this probiotic work if my child is on antibiotics?
No — antibiotics kill the live bacteria in probiotics, so they won't work well together. Space them apart by a few hours, with your doctor's or pharmacist's guidance on the best timing. Once the antibiotic course is done, the probiotic can resume.
Is it safe for a young child?
MegaFlora Kids is generally well tolerated in healthy children. However, the safety data are limited, and there's a rare theoretical risk of serious infection in very ill, premature, or immune-compromised kids. If your child has any of those conditions, check with their doctor first.
What side effects might happen?
Bloating, flatulence, abdominal pain, and diarrhea are uncommon but can occur, especially when starting. One trial reported rash and itching, though it's unclear if the probiotic caused it. Most kids tolerate it without problems.
Does this actually help with digestive issues?
Lactobacillus acidophilus in this product is possibly effective for irritable bowel syndrome, antibiotic-associated diarrhea, and a few other conditions. Bifidobacterium bifidum is possibly effective for irritable bowel syndrome and respiratory infections. For most other uses, the evidence is still insufficient to know either way.
Can I give it during pregnancy or breastfeeding?
The ingredients rated here — Lactobacillus acidophilus, Bifidobacterium longum, Bifidobacterium bifidum, and Streptococcus thermophilus — are possibly safe during pregnancy and lactation, but the data are limited. Talk with your doctor or midwife before using it in pregnancy or while breastfeeding.
What are these bacteria actually for?
They're probiotics — live beneficial microorganisms meant to support your child's digestive health and immune function. Different strains may have different roles, though for most conditions the evidence is still developing.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if MegaFlora Kids Probiotic is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

MegaFlora Kids Probiotic label
Go deeper

The Full Monographs Behind MegaFlora Kids Probiotic’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lactobacillus Acidophilus

Interacts with 182 drugs

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...

Read the full Lactobacillus Acidophilus monograph → Herb & supplement monograph

Lactobacillus Delbrueckii

Interacts with 182 drugs

Lactobacillus delbrueckii is a 'friendly' bacterium used in food fermentation and sold as a probiotic, often as part of multi-strain products. It is generally considered safe for healthy peo...

Read the full Lactobacillus Delbrueckii monograph → Herb & supplement monograph

Lactobacillus Gasseri

Interacts with 182 drugs

Lactobacillus gasseri is a 'friendly' probiotic bacterium found naturally in the human gut, mouth, and vaginal tract, and in some fermented foods. Early research suggests it may help with di...

Read the full Lactobacillus Gasseri monograph → Herb & supplement monograph

Bifidobacterium Longum

Interacts with 182 drugs

Bifidobacterium longum is a 'friendly' bacterium found naturally in the human gut and used as a probiotic. It is generally well tolerated and is most studied for digestive issues, though evi...

Read the full Bifidobacterium Longum monograph → Herb & supplement monograph

Bifidobacterium Bifidum

Interacts with 182 drugs

Bifidobacterium bifidum is a 'friendly' bacteria (probiotic) that naturally lives in the human gut and is taken to support digestion and gut balance. Some evidence suggests probiotics may he...

Read the full Bifidobacterium Bifidum monograph → Herb & supplement monograph

Streptococcus Thermophilus

Streptococcus thermophilus is a friendly bacterium used as a probiotic, often combined with other strains in yogurt and supplements. It is generally well tolerated in healthy people and may...

Read the full Streptococcus Thermophilus monograph →
Sources

Sources & How We Checked

MegaFlora Kids Probiotic's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 85 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Lactobacillus Delbrueckii 9 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  3. Ranchal P, Gupta R, Goldberg R, A Lobo S, Pascual A, El Khoury MY. Penicillin-sensitive Lactobacillus jensenii bacteremia. Am J Ther 2021;28(2):e250-e252. PubMed
  4. Grazioli-Gauthier L, Rigamonti E, Leo LA, Martinetti Lucchini G, Lo Priore E, Bernasconi E. Lactobacillus jensenii mitral valve endocarditis: Case report, literature review and new perspectives. IDCases 2022;27:e01401. PubMed
  5. Toprak NU, Bozan T, Yilmaz S, Buyukbayrak EE, Tigen ET. Polymicrobial bacteremia due to Lactobacillus jensenii and Veillonella montpellierensis in a pregnant patient; case report and review of literature. Anaerobe 2022;75:102576. PubMed
  6. Chazan B, Raz R, Shental Y, Sprecher H, Colodner R. Bacteremia and pyelonephritis caused by Lactobacillus jensenii in a patient with urolithiasis. Isr Med Assoc J 2008;10(2):164-5.
  7. Neonakis IK, Skamagkas I, Stafylaki D, Maraki S. Lactobacillus delbrueckii urinary tract infection in a male patient: a case report. Germs 2022;12(2):304-307. PubMed
  8. Maillet F, Passeron A, Podglajen I, Ranque B, Pouchot J. Lactobacillus delbrueckii urinary tract infection in a male patient. Med Mal Infect 2019;49(3):226-228. PubMed
  9. Darbro BW, Petroelje BK, Doern GV. Lactobacillus delbrueckii as the cause of urinary tract infection. J Clin Microbiol 2009;47(1):275-7.

See these in context on the Lactobacillus Delbrueckii monograph →

Lactobacillus Gasseri 12 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Ramachandran L, Dontaraju VS, Patel K. Lactobacillus-associated spontaneous bacterial peritonitis in a liver cirrhosis patient on probiotics. Cureus. 2020;12(12):e11896. PubMed
  3. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  4. Ranchal P, Gupta R, Goldberg R, A Lobo S, Pascual A, El Khoury MY. Penicillin-sensitive Lactobacillus jensenii bacteremia. Am J Ther 2021;28(2):e250-e252. PubMed
  5. Grazioli-Gauthier L, Rigamonti E, Leo LA, Martinetti Lucchini G, Lo Priore E, Bernasconi E. Lactobacillus jensenii mitral valve endocarditis: Case report, literature review and new perspectives. IDCases 2022;27:e01401. PubMed
  6. Toprak NU, Bozan T, Yilmaz S, Buyukbayrak EE, Tigen ET. Polymicrobial bacteremia due to Lactobacillus jensenii and Veillonella montpellierensis in a pregnant patient; case report and review of literature. Anaerobe 2022;75:102576. PubMed
  7. Chazan B, Raz R, Shental Y, Sprecher H, Colodner R. Bacteremia and pyelonephritis caused by Lactobacillus jensenii in a patient with urolithiasis. Isr Med Assoc J 2008;10(2):164-5.
  8. Ramos-Coria D, Canto-Losa J, Carrillo-Vázquez D, Carbajal-Morelos L, Estrada-León R, Corona-Rodarte E. Lactobacillus gasseri liver abscess and bacteremia: a case report. BMC Infect Dis 2021;21(1):518. PubMed
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Bifidobacterium Longum 21 references
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Bifidobacterium Bifidum 7 references
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  2. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
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  6. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  7. Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed

See these in context on the Bifidobacterium Bifidum monograph →

Streptococcus Thermophilus 21 references
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See these in context on the Streptococcus Thermophilus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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