Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Klean Glutamine Ingredients & Drug Interactions

by Klean Athlete

Klean Glutamine label
See full label image
Powder Category: Amino Acid/protein
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Klean Glutamine against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Klean Glutamine is a dietary supplement by Klean Athlete with 1 active ingredient. Its ingredients are commonly taken for muscle recovery and sports performance, gut health and 'leaky gut', recovery from severe illness or injury.Based on those ingredients, 50 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Glutamine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Klean Glutamine by Klean Athlete

Ask about any prescription or over-the-counter medication and we check it for interactions with Klean Glutamine by Klean Athlete — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Klean Glutamine by Klean Athlete

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Klean Glutamine is a straightforward single-ingredient supplement. It contains glutamine, an amino acid your body makes and uses for gut health, immune function, and muscle recovery.

This product has no inactive fillers or other added ingredients.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Muscle recovery and sports performance support.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Postoperative recovery, Wound healing, Critical illness (trauma), Muscle protein synthesis — and 2 related terms.
  • The strongest evidence on file: Glutamine is rated "Possibly Effective" for Critical illness (trauma) (Natural Medicines).
  • Also on file: Glutamine is rated "Possibly Effective" for Postoperative recovery.
  • Also on file: Glutamine is rated "Possibly Ineffective" for Athletic performance.

The evidence behind glutamine is strongest for sickle cell disease, where it's considered effective. For other uses — HIV/AIDS-related wasting, recovery from surgery, and trauma or critical illness — the data shows it's possibly effective, meaning there's some promise but the evidence isn't as solid yet.

The evidence, ingredient by ingredient Glutamine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Glutamine is generally well tolerated in healthy adults. The most common side effects from oral use are digestive: belching, bloating, constipation, diarrhea, flatulence, nausea, vomiting, and stomach pain.

Headache and musculoskeletal pain have also been reported. A couple of isolated cases of dizziness, mania, or hypomania have been noted, usually at very high doses or in people with bipolar disorder.

If you have kidney or liver disease, use glutamine only under your doctor's supervision. There isn't enough safety data to recommend it during pregnancy as a supplement dose, though the evidence suggests it's likely safe — talk to your pharmacist or doctor about your specific situation.

The same goes for breastfeeding: there's little safety information available, so check with your clinician before taking supplement doses.

Side effects, ingredient by ingredient Glutamine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Glutamine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: seizure medications.
  • For scale: 50 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, double-check any anticonvulsant medications (seizure drugs) you're on. These are Moderate-severity interactions.

Altogether, these interactions span 50 individual medications, so run your exact medication names through the checker on this page.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Klean Glutamine is a single-ingredient powder that may help with sickle cell disease and possibly with post-surgery recovery or muscle wasting. If you take an anticonvulsant (seizure medication), you'll want to check your exact drug name with the tool below before starting.

Anyone with kidney or liver disease should talk to their doctor first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Klean Glutamine, straight from the product label.

Brand Klean Athlete
Barcode (UPC) 310539980699
Net contents 17.3 Ounce(s); 491 Gram(s)
Market status On market
Date entered into DSLD Nov 22, 2024
DSLD ID 321195
Product type Amino Acid/protein
Supplement form Powder
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Klean Glutamine by Klean Athlete, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
5.46 Gram(s)
Maximum serving Sizes:
5.46 Gram(s)
Servings per container
90
UPC/BARCODE
310539980699
IngredientAmount% DV
Glutamine5000 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Nutritional Supplements

Gluten-free, Non-GMO

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested usage: As a dietary supplement, adults take 1 scoop dissolved in 8-10 oz of liquid, or as directed by a coach, trainer, or health professional.

Precautions

Warning: If you are pregnant, nursing, have any health condition or taking any medication, consult your health care professional before using this product.

Keep out of the reach of children.

Use only if safety seal is intact.

Storage

Store in a cool, dry place.

General Statements

Packaged by weight not volume. Settling may occur. Scan to learn about our Klean manufacturing and certifications

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Klean Glutamine by Klean Athlete label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Klean Glutamine label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Klean Glutamine by Klean Athlete

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size5.46 Gram(s) Dosage formPowder Servings per container90 Amounts shown are per serving.

Glutamine

Interacts with
50 drugs
5000 mg per serving

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...

Glutamine monograph & interactions
Interaction report

Klean Glutamine by Klean Athlete Drug Interactions

Want to check YOUR meds against Klean Glutamine?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
50Drugs
50 Moderate

Ingredients driving the most interactions

Glutamine 50

Individual Drug Interactions

The ingredients in Klean Glutamine interact with 50 drugs. Click any drug to see the details.

1 of the 1 ingredient in Klean Glutamine interact with drugs. Each result below shows which ingredient is responsible. Glutamine

Each ingredient & the kinds of drugs it affects

For each ingredient in Klean Glutamine with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Glutamine1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
Glutamine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Klean Glutamine, from the product label.

Klean Athlete

See all Klean Athlete products
Name
Klean Athlete
Street Address
600 Boyce Road
City
Pittsburgh
State
PA
ZipCode
15205
Phone Number
1.855.255.5326
Web Address
www.kleanathlete.com
Pharmacist Counseling Corner

Klean Glutamine by Klean Athlete: Common Questions

Does Klean Glutamine by Klean Athlete interact with any medications?
Yes. Based on its ingredients, Klean Glutamine has a known interaction with 50 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Klean Glutamine contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is glutamine, and why is it in this product?
Glutamine is an amino acid your body makes naturally and uses for gut health, immunity, and muscle repair. People take it as a supplement to support recovery from illness, surgery, or intense physical stress.
Will this help me recover from surgery?
Glutamine is possibly effective for postoperative recovery based on current evidence — there's some research support, but it's not as proven as it is for sickle cell disease. Talk to your surgeon or doctor about whether it's worth trying for your situation.
What are the most common side effects?
Most people taking glutamine orally experience digestive symptoms: bloating, gas, diarrhea, constipation, nausea, or stomach pain. Headache is also possible. These tend to be mild and often go away, especially if you reduce your dose.
Is it safe if I'm pregnant or breastfeeding?
Glutamine is likely safe during pregnancy, but there isn't enough data on supplement doses while breastfeeding. Talk with your doctor or pharmacist about your individual situation before starting, especially if you're breastfeeding.
Can I take this if I have kidney or liver problems?
If you have kidney or liver disease, you should only take glutamine under your doctor's supervision. Your doctor will know whether it's safe for your specific condition.
Does this product have fillers or other ingredients?
No — Klean Glutamine is pure glutamine powder with no inactive ingredients, binders, or fillers added.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Klean Glutamine is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Klean Glutamine label
Go deeper

The Full Monographs Behind Klean Glutamine’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glutamine

Interacts with 50 drugs

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle cell disease complications, but for most...

Read the full Glutamine monograph →
Sources

Sources & How We Checked

Klean Glutamine's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team