Interactions on record — worth a quick check against your medications. Based on 4 of 6 ingredients. Check your meds →
Dietary supplement

Kyo-Green Powdered Drink Mix Ingredients & Drug Interactions

by Kyo-Green

Kyo-Green Powdered Drink Mix label
See full label image
Powder Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Kyo-Green Powdered Drink Mix against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Kyo-Green Powdered Drink Mix is a dietary supplement by Kyo-Green with 6 active ingredients. Its ingredients are commonly taken for thyroid support, iodine source, weight management.Based on those ingredients, 1,069 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Kelp, Chlorella, Barley. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Kyo-Green Powdered Drink Mix by Kyo-Green

Ask about any prescription or over-the-counter medication and we check it for interactions with Kyo-Green Powdered Drink Mix by Kyo-Green — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Kyo-Green Powdered Drink Mix by Kyo-Green

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 13, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 6 active ingredients.
  • “Kyo-Green Powder Proprietary Blend” is a proprietary blend — the label gives one combined amount (2.50 Gram(s)) without saying how much of each component you get.

Kyo-Green contains six active ingredients: kelp (a seaweed rich in iodine), chlorella (a single-celled algae), barley, wheat grass, fructooligosaccharides (FOS, a type of prebiotic fiber), and brown rice. The proprietary blend formula combines several of these components in amounts the manufacturer doesn't disclose individually.

The powder also contains inactive ingredients — potato starch, vitamin C, beta-carotene, licorice extract, and guar gum — which serve as fillers and binders.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: immune support and cardiovascular health.
  • We looked for evidence on: Cardiovascular disease (CVD), Coronary heart disease (CHD), Hypercholesterolemia, Hyperlipidemia, Hypertension, Digestive health — and 2 related terms.
  • The strongest evidence on file: Barley is rated "Likely Effective" for Coronary heart disease (CHD) (Natural Medicines).
  • Also on file: Barley is rated "Likely Effective" for Hypercholesterolemia.
  • Also on file: Fucus Vesiculosus is rated "Insufficient Reliable Evidence To Rate" for Cardiovascular disease (CVD), Hypercholesterolemia.

Evidence for Kyo-Green's uses is mixed and incomplete. Barley shows solid support for lowering cholesterol and reducing heart disease risk.

Chlorella may help with pregnancy-related iron deficiency, though the evidence is not conclusive. For the other claimed uses — aging skin, cardiovascular health, constipation, diarrhea, indigestion, fatigue, brain tumors, and fatty liver — the evidence we hold is insufficient to rate whether the product actually works.

You'd want to talk with your doctor about whether Kyo-Green makes sense for your specific reason for considering it.

The evidence, ingredient by ingredient Fucus Vesiculosus Chlorella Barley Couch Grass

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Kelp is the safety wild card here because of its variable and sometimes high iodine content, which can disrupt your thyroid and the plant may concentrate heavy metals from seawater. Chlorella is generally well tolerated short term, but product purity and quality vary widely, and safety data long term remain limited.

Barley is safe as a food — most people eat it without trouble — but it contains gluten. Wheat grass has limited human safety data.

Most common side effects from chlorella are mild — cramping, nausea, diarrhea, bloating, or discolored stool, often in the first two weeks. Barley may cause bloating, gas, and unpleasant taste; allergic reactions are rare but possible.

Kelp's main risks are thyroid problems — goiter, overactive thyroid, or underactive thyroid — and a very rare risk of thyroid cancer. One case report linked a kelp-containing product to heart rhythm problems.

Side effects, ingredient by ingredient Fucus Vesiculosus Chlorella Barley Couch Grass

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 4 matched ingredients can interact with medications — Fucus Vesiculosus, Barley, Chlorella.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; lithium.
  • For scale: 1,070 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Double-check this product with your doctor or pharmacist if you take lithium (risk of thyroid problems), antithyroid drugs, thyroid hormone, or amiodarone — kelp's iodine can disrupt thyroid function across all these. Warfarin or other blood thinners (chlorella may reduce effectiveness and kelp may theoretically increase bleeding risk).

Any medication processed by your liver's CYP2D6, CYP2C9, or CYP3A4 enzymes (kelp may theoretically alter their levels). Triclabendazole for certain worm infections (barley may theoretically reduce its effect, though this hasn't been proven in humans).

Photosensitizing drugs if you're taking them (chlorella may increase sun sensitivity). If none of these apply, no interactions are documented for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Kyo-Green is best suited for people without thyroid conditions or medications that interact with iodine, blood thinners, or photosensitizing drugs. Barley's cholesterol and heart benefits have real evidence, but the other ingredients lack clear proof of effectiveness for their marketed uses.

If you take lithium, any thyroid medication, warfarin, amiodarone, or medications metabolized by your liver, check with your doctor or pharmacist before adding this product — the iodine content and other potential interactions could alter how your medicines work. The same goes if you're pregnant, breastfeeding, or allergic to any seaweed, algae, or grain products.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Kyo-Green Powdered Drink Mix, straight from the product label.

Brand Kyo-Green
Barcode (UPC) 023542700559
Net contents 2.8 Oz(s); 80 Gram(s)
Market status On market
Date entered into DSLD Feb 25, 2015
DSLD ID 42450
Product type Other Combinations
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Kyo-Green Powdered Drink Mix by Kyo-Green, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 tsp
Maximum serving Sizes:
1 tsp
UPC/BARCODE
023542700559
IngredientAmount% DV
Kelp0 NP--
Chlorella0 NP--
Barley0 NP--
Wheat Grass0 NP--
FOS0 NP--
Kyo-Green Powder Proprietary Blend2.5 Gram(s)--
cooked Brown Rice0 NP--

Other ingredients: Potato Starch, Vitamin C, Beta-Carotene, Licorice extract, Guar Gum

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

KYO-GREEN powdered drink mix is the best combination of nutrients from the Land and Sea.

KYO-GREEN gives you a gentle, long-lasting boost. Taken daily, it promotes healthy intestinal conditions and regularity by supporting beneficial bacteria.

Product of Japan

ENERGY

Go for the Green with KYO-GREEN, America's favorite green drink mix!

Formula

Immune supporting Barley and Wheat grasses grown in the pristine highlands of Japan are blended with protein-rich, readily-absorbable Chlorella and Kelp to support cardiovascular health.

Young Barley Grass Young Wheat Grass Brown Rice Chlorella Kelp FOS

Suggested/Recommended/Usage/Directions

Mix KYO-GREEN in water or your favorite juice to make a refreshing and tasty drink.

Suggested Use: Mix one teaspoon of powder with six to eight ounces (one cup) of juice or water.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

SAFETY SEALED: Do not use if inner seal is broken or missing.

California Proposition 65 Statement WARNING: This product contains lead, a chemical known to the state of California to cause cancer, birth defects or other reproductive harm.

Keep out of reach of children.

FDA Statement of Identity

Nutritional Supplement

Formulation

FREE OF: preservatives, yeast, gluten, milk, artificial colors and flavors.

Suitable for vegetarians.

Storage

Store in a cool, dry place with cap tightly closed and keep away from direct light.

Brand IP Statement(s)

"The KYOLIC(R) People"

General

L700A55Q

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Kyo-Green Powdered Drink Mix by Kyo-Green label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Kyo-Green Powdered Drink Mix label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Kyo-Green Powdered Drink Mix by Kyo-Green

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 tsp Dosage formPowder Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Kyo-Green Powder Proprietary Blend

2.5 Gram(s) per serving

Other (inactive) ingredients: Potato Starch, Vitamin C, Beta-Carotene, Licorice extract, Guar Gum. These complete the product’s ingredient list but are not active constituents.

Interaction report

Kyo-Green Powdered Drink Mix by Kyo-Green Drug Interactions

Want to check YOUR meds against Kyo-Green Powdered Drink Mix?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,069Drugs
360 Moderate 709 Minor

Ingredients driving the most interactions

Kelp 891
Chlorella 337
Barley 1

Individual Drug Interactions

The ingredients in Kyo-Green Powdered Drink Mix interact with 1,069 drugs. Click any drug to see the details.

3 of the 6 ingredients in Kyo-Green Powdered Drink Mix interact with drugs. Each result below shows which ingredient is responsible. Kelp Chlorella Barley

Each ingredient & the kinds of drugs it affects

For each ingredient in Kyo-Green Powdered Drink Mix with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Kelp9 drug types · 891 drugs

Amiodarone (Cordarone)

Theoretically, combining Fucus vesiculosus with amiodarone might cause excessively high iodine levels.
Fucus vesiculosus contains high concentrations of iodine. Amiodarone contains 37.3% iodine and can increase iodine levels. Concomitant use might increase the risk of having excessive iodine levels and adversely affecting thyroid function. Monitor thyroid function.

Likelihood Probable Evidence D
Antithyroid Drugs

Due to its iodine content, Fucus vesiculosus might alter the effects of antithyroid drugs.
Fucus vesiculosus contains high concentrations of iodine. Iodine in high doses has been reported to cause both hyperthyroidism and hypothyroidism, depending on the individual's past medical history. Taking Fucus vesiculosus while using antithyroid drugs could alter the effects of the antithyroid drugs.

Likelihood Possible Evidence D
Lithium

Concomitant use of Fucus vesiculosus and lithium has resulted in hyperthyroidism.
There is a case of hyperthyroidism occurring in a patient taking Fucus vesiculosus and lithium. Monitor thyroid hormones closely in patients taking lithium and Fucus vesiculosus concomitantly.

Likelihood Possible Evidence D
Thyroid Hormone

Due to its iodine content, Fucus vesiculosus might alter the effects of thyroid hormone.
Fucus vesiculosus contains high concentrations of iodine. Iodine in high doses has been reported to cause both hyperthyroidism and hypothyroidism, depending on the individual's past medical history. Taking Fucus vesiculosus while using thyroid hormone could alter the effects of thyroid hormone.

Likelihood Possible Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, taking Fucus vesiculosus with antiplatelet or anticoagulant drugs might increase the risk of bruising and bleeding.
In vitro evidence suggests that a constituent of Fucus vesiculosus, known as fucoidan, has anticoagulant effects. However, in clinical research, fucoidan does not seem to have significant anticoagulant activity when taken orally, possibly due to poor absorption.

Likelihood Unlikely Evidence D
Cytochrome P450 2C8 (Cyp2C8) Substrates

Theoretically, concomitant use of Fucus vesiculosus with CYP2C8 substrates might increase the risk for adverse effects.
In vitro research shows that fucoidan, a constituent of Fucus vesiculosus, inhibits CYP2C8. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, concomitant use of Fucus vesiculosus with CYP2C9 substrates might increase the risk for adverse effects.
In vitro research shows that fucoidan, a constituent of Fucus vesiculosus, inhibits CYP2C9. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, concomitant use of Fucus vesiculosus with CYP2D6 substrates might alter the effects of these substrates.
In vitro research shows that fucoidan, a constituent of Fucus vesiculosus, both inhibits and induces CYP2D6. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
In vitro research shows that fucoidan, a constituent of Fucus vesiculosus, inhibits CYP3A4. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Kelp full monograph & interactions

Chlorella2 drug types · 337 drugs

Photosensitizing Drugs

Theoretically, chlorella might have additive effects with photosensitizing drugs.
Chlorella has been reported to cause photosensitization. In five case reports, patients who had ingested chlorella exhibited swelling followed by erythematopurpuric lesions on sun-exposed areas of the body. Theoretically, concomitant use with photosensitizing drugs may exacerbate effects.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, chlorella might reduce the clinical effects of warfarin.
Chlorella contains significant amounts of vitamin K. There is at least one case report of warfarin therapy becoming sub-therapeutic after initiation of chlorella supplements.

Likelihood Possible Evidence D
Chlorella full monograph & interactions

Barley1 drug type · 1 drug

Triclabendazole (Egaten)

Theoretically, barley might decrease the clinical effects of triclabendazole.
Animal research suggests that a diet supplemented with barley can reduce the bioavailability of triclabendazole when taken concomitantly. This effect has not been shown in humans.

Likelihood Possible Evidence D
Barley full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Kyo-Green Powdered Drink Mix, from the product label.

Kyo-Green

See all Kyo-Green products
Name
Wakunaga of America Co., Ltd.
Street Address
23501 Madero
City
Mission Viejo
State
CA
ZipCode
92691
Web Address
www.kyolic.com
Pharmacist Counseling Corner

Kyo-Green Powdered Drink Mix by Kyo-Green: Common Questions

Does Kyo-Green Powdered Drink Mix by Kyo-Green interact with any medications?
Yes. Based on its ingredients, Kyo-Green Powdered Drink Mix has a known interaction with 1,069 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Kyo-Green Powdered Drink Mix contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Kyo-Green if I'm pregnant or breastfeeding?
The safety data advise against it. Kelp's iodine and possible heavy metals make it unsafe during pregnancy, and iodine passes into breast milk and could affect your baby's thyroid. Talk with your doctor before considering it.
What's the most common side effect I might notice?
Chlorella, a key ingredient, often causes mild cramping, nausea, diarrhea, or bloating — especially in the first two weeks. Barley may add bloating or gas. These are usually temporary, but if they persist, stop and check with your pharmacist.
Does Kyo-Green actually lower cholesterol?
Barley, one of its ingredients, has solid evidence for lowering cholesterol and reducing heart disease risk. For the other uses Kyo-Green markets — skin, fatigue, digestion — the evidence we hold isn't enough to say whether it works.
Will this interfere with my warfarin?
Possibly, yes. Chlorella contains vitamin K, which can reduce warfarin's blood-thinning effect. There's at least one case report of this happening. Check with your doctor or pharmacist before starting.
Is this product safe for people with thyroid problems?
It's risky because kelp has very high iodine content, which can worsen overactive or underactive thyroid. If you have any thyroid condition or take thyroid medication, talk with your doctor first.
Does Kyo-Green contain gluten?
Barley is a gluten grain, so this product likely contains gluten. If you have celiac disease or gluten sensitivity, avoid it unless the label states it's gluten-free.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Kyo-Green Powdered Drink Mix label
Go deeper

The Full Monographs Behind Kyo-Green Powdered Drink Mix’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Fucus Vesiculosus

Interacts with 891 drugs

Fucus vesiculosus (bladderwrack) is a brown seaweed rich in iodine that has been used traditionally for thyroid concerns, weight, and skin. There is little solid human evidence to support mo...

Read the full Fucus Vesiculosus monograph → Herb & supplement monograph

Chlorella

Interacts with 337 drugs

Chlorella is a nutrient-rich freshwater green algae taken as a supplement for general wellness, immune support, and 'detox.' Some small studies suggest possible benefits for cholesterol, blo...

Read the full Chlorella monograph → Herb & supplement monograph

Barley

Interacts with 1 drug

Barley is a nutritious whole grain that is a good source of soluble fiber called beta-glucan, which has solid evidence for modestly lowering LDL ('bad') cholesterol when eaten regularly. It...

Read the full Barley monograph → Herb & supplement monograph

Couch Grass

Couch grass is a common lawn weed whose rhizome has long been used in traditional European herbal medicine, mainly for urinary and bladder complaints. High-quality human studies are lacking,...

Read the full Couch Grass monograph →
Sources

Sources & How We Checked

Kyo-Green Powdered Drink Mix's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 43 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Fucus Vesiculosus 15 references
  1. Goodman GA, Rall TW, Nies AS, Taylor P. The Pharmacological Basis of Therapeutics, 9th ed.
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  3. Phaneuf D, Cote I, Dumas P, et al. Evaluation of the contamination of marine algae (Seaweed) from the St. Lawrence River and likely to be consumed by humans. Environ Res 1999;80:S175-S182. PubMed
  4. Durig J, Bruhn T, Zurborn KH, et al. Anticoagulant fucoidan fractions from Fucus vesiculosus induce platelet activation in vitro. Thromb Res 1997;85:479-91. PubMed
  5. Conz PA, La Greca G, Benedetti P, et al. Fucus vesiculosus: a nephrotoxic alga? Nephrol Dial Transplant 1998;13:526-7.
  6. Ohye H, Fukata S, Kanoh M, et al. Thyrotoxicosis caused by weight-reducing herbal medicines. Arch Intern Med 2005;165:831-4. PubMed
  7. Okamura K, Inoue K, Omae T. A case of Hashimoto's thyroiditis with thyroid immunological abnormality manifested after habitual ingestion of seaweed. Acta Endocrinol (Copenh) 1978;88:703-12. PubMed
  8. Agarwal SC, Crook JR, Pepper CB. Herbal remedies -- how safe are they? A case report of polymorphic ventricular tachycardia/ventricular fibrillation induced by herbal medication used for obesity. Int J Cardiol 2006;106:260-1. PubMed
  9. Sterling JB, Heymann WR. Potassium iodide in dermatology: a 19th century drug for the 21st century-uses, pharmacology, adverse effects, and contraindications. J Am Acad Dermatol 2000;43:691-7. PubMed
  10. Catania, M. A., Oteri, A., Caiello, P., Russo, A., Salvo, F., Giustini, E. S., Caputi, A. P., and Polimeni, G. Hemorrhagic cystitis induced by an herbal mixture. South.Med.J. 2010;103(1):90-92. PubMed
  11. Cumashi, A., Ushakova, N. A., Preobrazhenskaya, M. E., D'Incecco, A., Piccoli, A., Totani, L., Tinari, N., Morozevich, G. E., Berman, A. E., Bilan, M. I., Usov, A. I., Ustyuzhanina, N. E., Grachev, A. A., Sanderson, C. J., Kelly, M., Rabinovich, G. A., I
  12. Irhimeh, M. R., Fitton, J. H., and Lowenthal, R. M. Pilot clinical study to evaluate the anticoagulant activity of fucoidan. Blood Coagul.Fibrinolysis 2009;20(7):607-610. PubMed
  13. Arbaizar, B. and Llorca, J. [Fucus vesiculosus induced hyperthyroidism in a patient undergoing concomitant treatment with lithium]. Actas Esp.Psiquiatr. 2011;39(6):401-403.
  14. Church FC, Meade JB, Treanor RE, and et al. Antithrombin activity of fucoidan. The interaction of fucoidan with heparin cofactor II, antithrombin III, and thrombin. J Biol Chem 2-25-1989;264(6):3618-3623. DOI
  15. Mathew L, Burney M, Gaikwad A, et al. Preclinical evaluation of safety of fucoidan extracts from Undaria pinnatifida and Fucus vesiculosus for use in cancer treatment. Integr Cancer Ther 2017;16(4):572-84.

See these in context on the Fucus Vesiculosus monograph →

Chlorella 13 references
  1. Peirce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York, NY: William Morrow and Co., 1999.
  2. Ng TP, Tan WC, Lee YK. Occupational asthma in a pharmacist induced by chlorella, a unicellular algae preparation. Resp Med 1994;88:555-7. PubMed
  3. Jitsukawa K, Suizu R, Hidano A. Chlorella photosensitization. New phytophotodermatosis. Int J Dermatol 1984;23:263-8. PubMed
  4. Merchant RE, Carmack CA, Wise CM. Nutritional supplementation with Chlorella pyrenoidosa for patients with fibromyalgia syndrome: a pilot study. Phytother Res 2000;14:167-73.
  5. Merchant RE, Rice CD, Young HF. Dietary Chlorella pyrenoidosa for patients with malignant glioma: effects on immunocompetence, quality of life, and survival. Phytother Res 1990;4:220-31.
  6. Halperin SA, Smith B, Nolan C, et al. Safety and immunoenhancing effect of a Chlorella-derived dietary supplement in healthy adults undergoing influenza vaccination: randomized, double-blind, placebo-controlled trial. CMAJ 2003;169:111-7..
  7. Ohtake, T., Negishi, K., Okamoto, K., Oka, M., Maesato, K., Moriya, H., and Kobayashi, S. Manganese-induced Parkinsonism in a patient undergoing maintenance hemodialysis. Am J Kidney Dis 2005;46(4):749-753. PubMed
  8. Ng, T. P., Tan, W. C., and Lee, Y. K. Occupational asthma in a pharmacist induced by Chlorella, a unicellular algae preparation. Respir.Med. 1994;88(7):555-557. PubMed
  9. Ohkawa, S., Yoneda, Y., Ohsumi, Y., and Tabuchi, M. [Warfarin therapy and chlorella]. Rinsho Shinkeigaku 1995;35(7):806-807.
  10. Azocar J, Diaz A. Efficacy and safety of chlorella supplementation in adults with chronic hepatitis C virus infection. World J Gastroenterol 2013;19(7):1085-90. PubMed
  11. Panahi Y, Badeli R, Karami GR, Badeli Z, Sahebkar A. A randomized controlled trial of 6-week Chlorella vulgaris supplementation in patients with major depressive disorder. Complement Ther Med 2015;23(4):598-602. PubMed
  12. Nakano S, Takekoshi H, Nakano M. Chlorella pyrenoidosa supplementation reduces the risk of anemia, proteinuria and edema in pregnant women. Plant Foods Hum Nutr 2010;65(1):25-30. PubMed
  13. Yavasoglu I, Turgutkaya A, Bolaman Z. Chlorella-induced thrombocytopenia. Sao Paulo Med J 2018;136(6):602-3. PubMed

See these in context on the Chlorella monograph →

Barley 15 references
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Fernandez-Anaya S, Crespo JF, Rodriguez JR, et al. Beer anaphylaxis. J Allergy Clin Immunol 1999;103:959-60.
  3. Lembo A, Camilleri M. Chronic constipation. N Engl J Med 2003;349:1360-8. . PubMed
  4. Ferre, I., Giraldez, F. J., Alvarez-Bujidos, M. L., and Mantecon, A. R. Influence of barley supplement on plasma concentration of triclabendazole metabolites in sheep. Vet.Rec. 11-22-1997;141(21):549-551. PubMed
  5. Curioni, A., Santucci, B., Cristaudo, A., Canistraci, C., Pietravalle, M., Simonato, B., and Giannattasio, M. Urticaria from beer: an immediate hypersensitivity reaction due to a 10- kDa protein derived from barley. Clin Exp Allergy 1999;29(3):407-413. PubMed
  6. Fernandez-Anaya, S., Crespo, J. F., Rodriguez, J. R., Daroca, P., Carmona, E., Herraez, L., and Lopez-Rubio, A. Beer anaphylaxis. J Allergy Clin Immunol. 1999;103(5 Pt 1):959-960.
  7. Cronin, E. Contact dermatitis from barley dust. Contact Dermatitis 1979;5(3):196. PubMed
  8. Block, G., Tse, K. S., Kijek, K., Chan, H., and Chan-Yeung, M. Baker's asthma. Studies of the cross-antigenicity between different cereal grains. Clin Allergy 1984;14(2):177-185.
  9. van Ketel, W. G. Immediate type allergy to malt in beer. Contact Dermatitis 1980;6(4):297-298. PubMed
  10. Ellis, H. J., Doyle, A. P., Day, P., Wieser, H., and Ciclitira, P. J. Demonstration of the presence of coeliac-activating gliadin-like epitopes in malted barley. Int Arch Allergy Immunol. 1994;104(3):308-310. PubMed
  11. Vidal, C. and Gonzalez-Quintela, A. Food-induced and occupational asthma due to barley flour. Ann Allergy Asthma Immunol. 1995;75(2):121-124.
  12. Gutgesell, C. and Fuchs, T. Contact urticaria from beer. Contact Dermatitis 1995;33(6):436-437. PubMed
  13. Baker, P. G. and Read, A. E. Oats and barley toxicity in coeliac patients. Postgrad.Med J 1976;52(607):264-268. PubMed
  14. Nakase, M., Usui, Y., Alvarez-Nakase, A. M., Adachi, T., Urisu, A., Nakamura, R., Aoki, N., Kitajima, K., and Matsuda, T. Cereal allergens: rice-seed allergens with structural similarity to wheat and barley allergens. Allergy 1998;53(46 Suppl):55-57. PubMed
  15. Pereira, F., Rafael, M., and Lacerda, M. H. Contact dermatitis from barley. Contact Dermatitis 1998;39(5):261-262. PubMed

See these in context on the Barley monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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