Kyo-Green Powdered Drink Mix Ingredients & Drug Interactions
by Kyo-Green
What is this page for?
First and foremost: checking Kyo-Green Powdered Drink Mix against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Kyo-Green Powdered Drink Mix is a dietary supplement by Kyo-Green with 6 active ingredients. Its ingredients are commonly taken for thyroid support, iodine source, weight management.Based on those ingredients, 1,069 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Kelp, Chlorella, Barley Grass. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Kyo-Green Powdered Drink Mix by Kyo-Green
Ask about any prescription or over-the-counter medication and we check it for interactions with Kyo-Green Powdered Drink Mix by Kyo-Green — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Kyo-Green Powdered Drink Mix by Kyo-Green
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Kyo-Green contains 6 active ingredients: kelp, FOS, chlorella, barley grass, wheat grass, and cooked brown rice. Kelp and chlorella are nutrient-dense algae; barley grass and wheat grass are concentrated plant juices from young grains; FOS is a fiber that may support digestion; and brown rice rounds out the base.
The product also includes inactive ingredients—potato starch, vitamin C, beta-carotene, licorice extract, and guar gum—which serve as fillers, binders, and flavor.
Does it work?
Not established
The evidence for most uses is weak. Barley grass stands out as likely effective for high cholesterol and heart disease.
Chlorella is possibly effective for pregnancy-related iron deficiency. For the other claimed uses—constipation, diarrhea, aging skin, cardiovascular health, and digestive comfort—the evidence isn't established in the data we hold.
Wheat grass, FOS, and brown rice have no effectiveness ratings on file.
How safe is it?
Well-documented data
Orally, this product is generally well tolerated short term, but kelp's high iodine content is a major concern. The most common side effects are digestive—bloating, gas, abdominal cramping, and loose stools—especially when you first start.
Chlorella can cause allergic reactions including asthma and rarely anaphylaxis; kelp can trigger thyroid problems like goiter or overactive thyroid. Barley grass contains gluten.
The safety facts advise against use in pregnancy due to excess iodine and heavy metal risk, and against breastfeeding because iodine passes into milk and may affect the baby's thyroid.
Meds to double-check
Moderate interaction found
Before taking Kyo-Green, check with your own doctor or pharmacist if you take lithium, antithyroid drugs, thyroid hormone, amiodarone, warfarin, photosensitizing drugs, or blood thinners. Kelp's iodine can disrupt thyroid function and interfere with lithium therapy, and chlorella may weaken warfarin's effect.
Minor interactions with certain liver-metabolized drugs (CYP2D6, CYP2C9, and CYP3A4 substrates) and anticoagulants are also listed.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
If you have heart disease or high cholesterol and don't take lithium, thyroid medication, amiodarone, or blood thinners, this product may be worth discussing with your doctor. Anyone on those medications or with thyroid disease should steer clear.
If you're pregnant or breastfeeding, the safety data advises against it. Talk it over with your own doctor or pharmacist before you start.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 4 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 24, 2019.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Kyo-Green Powdered Drink Mix, straight from the product label.
| Brand | Kyo-Green |
|---|---|
| Barcode (UPC) | 023542700511 |
| Net contents | 10 oz.; 283 Gram(s) |
| Market status | On market |
| Date entered into DSLD | Sep 24, 2019 |
| DSLD ID | 205199 |
| Product type | Other Combinations |
| Supplement form | Powder |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Kyo-Green Powdered Drink Mix by Kyo-Green, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Kelp | 0 NP | -- |
| FOS | 0 NP | -- |
| Chlorella | 0 NP | -- |
| Barley Grass | 0 NP | -- |
| Wheat Grass | 0 NP | -- |
| cooked Brown Rice | 0 NP | -- |
| Kyo-Green Powder Proprietary Blend | 2.5 Gram(s) | -- |
Other ingredients: Potato Starch, Vitamin C, Beta-Carotene, Licorice extract, Guar Gum
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Kyo-Green powdered drink mix is the best combination of nutrients from the land and sea. Immune supporting Barley and Wheat grasses grown in the pristine highlands of Japan are blended with protein-rich, readily-absorbable Chlorella and Kelp to support cardiovascular health.
California Proposition 65 Statement Warning: This product contains lead, a chemical known to the state of California to cause birth defects or other reproductive harm.
Young Barley Grass Young Wheat Grass Brown Rice Chlorella Kelp Fos
General Statements
Kyo-Green gives gentle, long-lasting boost. Taken daily, it promotes healthy intestinal conditions and regularity by supporting beneficial bacteria.
Go for the green with Kyo-Green, America's favorite green drink mix!
Product of Japan
Energy
Suggested/Recommended/Usage/Directions
Mix Kyo-Green in water or your favorite juice to make a refreshing and tasty drink.
Suggested Use: Mix one teaspoon of powder with six to eight ounces (one cup) of juice water.
FDA Disclaimer Statement
Theses statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Precautions
Safety sealed: Do not use if inner seal or plastic shrink wrap is broken or missing.
California Proposition 65 Statement Warning: This product contains lead, a chemical known to the state of California to cause birth defects or other reproductive harm.
Keep out of reach of children.
FDA Statement of Identity
Nutritional Supplement
Formulation
Free of: preservatives, milk, yeast, gluten, artificial colors and flavors.
Suitable for vegetarians.
Storage
Store in a cool, dry place with cap tightly closed and keep away from direct light.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Kyo-Green Powdered Drink Mix by Kyo-Green label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Kyo-Green Powdered Drink Mix by Kyo-Green
These are the 6 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 tsp Dosage formPowder Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Kyo-Green Powder Proprietary Blend
- › Kelp
- › FOS
- › Chlorella
- › Barley Grass
- › Wheat Grass
- › Cooked Brown Rice
Other (inactive) ingredients: Potato Starch, Vitamin C, Beta-Carotene, Licorice extract, Guar Gum. These complete the product’s ingredient list but are not active constituents.
Kyo-Green Powdered Drink Mix by Kyo-Green Drug Interactions
HelloPharmacist Interaction Report
Kyo-Green Powdered Drink Mix has documented interactions through its kelp and chlorella content.
The most serious concern is with lithium — kelp's high iodine can trigger overactive thyroid (hyperthyroidism) in people taking lithium for bipolar disorder, and there's a documented case of this happening. Kelp also interacts with antithyroid drugs, thyroid hormone replacement, and amiodarone (a heart rhythm medication), all at Moderate severity, because its iodine content can disrupt how your thyroid works and increase iodine to unsafe levels.
Read the full breakdown — every affected drug type, severity by severity
Chlorella adds two Moderate interactions: it may reduce how well warfarin (a blood thinner) works because of its vitamin K content, and it can make your skin extra sensitive to sun (photosensitization) if you're also on photosensitizing drugs. Kelp also carries theoretical Minor interactions affecting how your liver breaks down certain drug classes (CYP2D6, CYP2C9, and CYP3A4 substrates), and it may theoretically increase bleeding risk with blood thinners (anticoagulants) or antiplatelet drugs, though these haven't been confirmed in people.
We could not check FOS or cooked brown rice — no data are on file for those ingredients. Barley grass and wheat grass were checked; barley has one Moderate interaction with triclabendazole (an antiparasitic), and wheat grass showed no documented interactions.
Additionally, use the medication search tool on this page to check your exact prescriptions before starting. Altogether, these interactions span 1,070 individual medications.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Kyo-Green Powdered Drink Mix?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Kyo-Green Powdered Drink Mix interact with 1,069 drugs. Click any drug to see the details.
3 of the 6 ingredients in Kyo-Green Powdered Drink Mix interact with drugs. Each result below shows which ingredient is responsible. Kelp Chlorella Barley Grass
AcepromazineAtravet
How Acepromazine interacts with Kyo-Green Powdered Drink Mix — through 1 ingredient. Tap an ingredient for the detail:
ChlorellaPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Chlorella + Acepromazine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Kyo-Green Powdered Drink Mix — through 1 ingredient. Tap an ingredient for the detail:
ChlorellaPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Chlorella + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Kyo-Green Powdered Drink Mix — through 2 ingredients. Tap an ingredient for the detail:
ChlorellaPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Chlorella + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionKelpCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP2D6 substrates might alter the effects of these substrates.
Read the full Kelp + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Kyo-Green Powdered Drink Mix — through 2 ingredients. Tap an ingredient for the detail:
ChlorellaPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Chlorella + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionKelpCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP2D6 substrates might alter the effects of these substrates.
Read the full Kelp + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Kyo-Green Powdered Drink Mix — through 2 ingredients. Tap an ingredient for the detail:
ChlorellaPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Chlorella + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionKelpCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Kelp + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Kyo-Green Powdered Drink Mix — through 2 ingredients. Tap an ingredient for the detail:
ChlorellaPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Chlorella + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionKelpCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP2D6 substrates might alter the effects of these substrates.
Read the full Kelp + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Kyo-Green Powdered Drink Mix — through 2 ingredients. Tap an ingredient for the detail:
ChlorellaPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Chlorella + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionKelpCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Kelp + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Kyo-Green Powdered Drink Mix — through 2 ingredients. Tap an ingredient for the detail:
ChlorellaPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Chlorella + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionKelpCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP2D6 substrates might alter the effects of these substrates.
Read the full Kelp + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Kyo-Green Powdered Drink Mix — through 2 ingredients. Tap an ingredient for the detail:
ChlorellaPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Chlorella + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionKelpCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Kelp + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Kyo-Green Powdered Drink Mix — through 2 ingredients. Tap an ingredient for the detail:
ChlorellaPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Chlorella + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionKelpCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Kelp + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Kyo-Green Powdered Drink Mix — through 2 ingredients. Tap an ingredient for the detail:
ChlorellaPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Chlorella + Acetaminophen, Chlorpheniramine, Phenylephrine interactionKelpCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Kelp + Acetaminophen, Chlorpheniramine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylephrine, SalicylamideRhinogesic, Rhinogesic JR
How Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interacts with Kyo-Green Powdered Drink Mix — through 2 ingredients. Tap an ingredient for the detail:
ChlorellaPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Chlorella + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionKelpCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Kelp + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylpropanolamineAlumadrine, Conex, Sinadrin Max Strength, Sinulin
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine interacts with Kyo-Green Powdered Drink Mix — through 2 ingredients. Tap an ingredient for the detail:
ChlorellaPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Chlorella + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionKelpCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Kelp + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with Kyo-Green Powdered Drink Mix — through 2 ingredients. Tap an ingredient for the detail:
ChlorellaPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Chlorella + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionKelpCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Kelp + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, PhenyltoloxamineNorel Plus
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interacts with Kyo-Green Powdered Drink Mix — through 2 ingredients. Tap an ingredient for the detail:
ChlorellaPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Chlorella + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionKelpCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Kelp + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionAcetaminophen, Chlorpheniramine, PseudoephedrineAlka-Seltzer PLUS Liquid Gels, Children's Tylenol Cold, Codimal, Comtrex, Extra Strength Tylenol Allergy Sinus, Lorsin +3 more
How Acetaminophen, Chlorpheniramine, Pseudoephedrine interacts with Kyo-Green Powdered Drink Mix — through 2 ingredients. Tap an ingredient for the detail:
ChlorellaPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Chlorella + Acetaminophen, Chlorpheniramine, Pseudoephedrine interactionKelpCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Kelp + Acetaminophen, Chlorpheniramine, Pseudoephedrine interactionAcetaminophen, Dexbrompheniramine, PseudoephedrineSinadrin Plus
How Acetaminophen, Dexbrompheniramine, Pseudoephedrine interacts with Kyo-Green Powdered Drink Mix — through 1 ingredient. Tap an ingredient for the detail:
ChlorellaPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Chlorella + Acetaminophen, Dexbrompheniramine, Pseudoephedrine interactionAcetaminophen, DiphenhydramineTylenol PM, Tylenol PM Ex Strength
How Acetaminophen, Diphenhydramine interacts with Kyo-Green Powdered Drink Mix — through 1 ingredient. Tap an ingredient for the detail:
ChlorellaPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Chlorella + Acetaminophen, Diphenhydramine interactionAcetaminophen, Diphenhydramine, PseudoephedrineChildren's Tylenol Allergy, Cold Control, Contac Night Allergy Relief
How Acetaminophen, Diphenhydramine, Pseudoephedrine interacts with Kyo-Green Powdered Drink Mix — through 1 ingredient. Tap an ingredient for the detail:
ChlorellaPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Chlorella + Acetaminophen, Diphenhydramine, Pseudoephedrine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Kyo-Green Powdered Drink Mix — through 2 ingredients. Tap an ingredient for the detail:
ChlorellaPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Chlorella + Acetaminophen, Ibuprofen interactionKelpCytochrome P450 2c9 (cyp2c9) Substrates, Anticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP2C9 substrates might increase the risk for adverse effects.
Read the full Kelp + Acetaminophen, Ibuprofen interactionAcetaminophen, Phenylephrine, ChlorpheniramineSuper Cold Tabs
How Acetaminophen, Phenylephrine, Chlorpheniramine interacts with Kyo-Green Powdered Drink Mix — through 2 ingredients. Tap an ingredient for the detail:
ChlorellaPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Chlorella + Acetaminophen, Phenylephrine, Chlorpheniramine interactionKelpCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Kelp + Acetaminophen, Phenylephrine, Chlorpheniramine interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Kyo-Green Powdered Drink Mix — through 1 ingredient. Tap an ingredient for the detail:
ChlorellaPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Chlorella + Acetazolamide interactionAcetohexamideDymelor
How Acetohexamide interacts with Kyo-Green Powdered Drink Mix — through 1 ingredient. Tap an ingredient for the detail:
ChlorellaPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Chlorella + Acetohexamide interactionAcitretinSoriatane
How Acitretin interacts with Kyo-Green Powdered Drink Mix — through 1 ingredient. Tap an ingredient for the detail:
ChlorellaPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Chlorella + Acitretin interactionAlectinib HydrochlorideAlecensa
How Alectinib Hydrochloride interacts with Kyo-Green Powdered Drink Mix — through 1 ingredient. Tap an ingredient for the detail:
ChlorellaPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Chlorella + Alectinib Hydrochloride interactionAlitretinoinPanretin
How Alitretinoin interacts with Kyo-Green Powdered Drink Mix — through 1 ingredient. Tap an ingredient for the detail:
ChlorellaPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Chlorella + Alitretinoin interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Kyo-Green Powdered Drink Mix — through 1 ingredient. Tap an ingredient for the detail:
ChlorellaPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Chlorella + Amiloride, Hydrochlorothiazide interactionAminolevulinic Acid HydrochlorideAmeluz, Gleolan
How Aminolevulinic Acid Hydrochloride interacts with Kyo-Green Powdered Drink Mix — through 1 ingredient. Tap an ingredient for the detail:
ChlorellaPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Chlorella + Aminolevulinic Acid Hydrochloride interactionAmiodaroneCordarone, Pacerone
How Amiodarone interacts with Kyo-Green Powdered Drink Mix — through 2 ingredients. Tap an ingredient for the detail:
KelpCytochrome P450 3a4 (cyp3a4) Substrates, Amiodarone (cordarone) +1 Moderate
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Kelp + Amiodarone interactionChlorellaPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Chlorella + Amiodarone interactionAmitriptylineElavil
How Amitriptyline interacts with Kyo-Green Powdered Drink Mix — through 2 ingredients. Tap an ingredient for the detail:
ChlorellaPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Chlorella + Amitriptyline interactionKelpCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 2c9 (cyp2c9) Substrates +1 Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP2D6 substrates might alter the effects of these substrates.
Read the full Kelp + Amitriptyline interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Kyo-Green Powdered Drink Mix with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Kelp
Amiodarone (Cordarone)
Theoretically, combining Fucus vesiculosus with amiodarone might cause excessively high iodine levels.
Fucus vesiculosus contains high concentrations of iodine. Amiodarone contains 37.3% iodine and can increase iodine levels. Concomitant use might increase the risk of having excessive iodine levels and adversely affecting thyroid function. Monitor thyroid function.
Antithyroid Drugs
Due to its iodine content, Fucus vesiculosus might alter the effects of antithyroid drugs.
Fucus vesiculosus contains high concentrations of iodine. Iodine in high doses has been reported to cause both hyperthyroidism and hypothyroidism, depending on the individual's past medical history. Taking Fucus vesiculosus while using antithyroid drugs could alter the effects of the antithyroid drugs.
Lithium
Concomitant use of Fucus vesiculosus and lithium has resulted in hyperthyroidism.
There is a case of hyperthyroidism occurring in a patient taking Fucus vesiculosus and lithium. Monitor thyroid hormones closely in patients taking lithium and Fucus vesiculosus concomitantly.
Thyroid Hormone
Due to its iodine content, Fucus vesiculosus might alter the effects of thyroid hormone.
Fucus vesiculosus contains high concentrations of iodine. Iodine in high doses has been reported to cause both hyperthyroidism and hypothyroidism, depending on the individual's past medical history. Taking Fucus vesiculosus while using thyroid hormone could alter the effects of thyroid hormone.
Anticoagulant/Antiplatelet Drugs
Theoretically, taking Fucus vesiculosus with antiplatelet or anticoagulant drugs might increase the risk of bruising and bleeding.
In vitro evidence suggests that a constituent of Fucus vesiculosus, known as fucoidan, has anticoagulant effects. However, in clinical research, fucoidan does not seem to have significant anticoagulant activity when taken orally, possibly due to poor absorption.
Cytochrome P450 2C8 (Cyp2C8) Substrates
Theoretically, concomitant use of Fucus vesiculosus with CYP2C8 substrates might increase the risk for adverse effects.
In vitro research shows that fucoidan, a constituent of Fucus vesiculosus, inhibits CYP2C8. This interaction has not been reported in humans.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, concomitant use of Fucus vesiculosus with CYP2C9 substrates might increase the risk for adverse effects.
In vitro research shows that fucoidan, a constituent of Fucus vesiculosus, inhibits CYP2C9. This interaction has not been reported in humans.
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, concomitant use of Fucus vesiculosus with CYP2D6 substrates might alter the effects of these substrates.
In vitro research shows that fucoidan, a constituent of Fucus vesiculosus, both inhibits and induces CYP2D6. This interaction has not been reported in humans.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
In vitro research shows that fucoidan, a constituent of Fucus vesiculosus, inhibits CYP3A4. This interaction has not been reported in humans.
Chlorella
Photosensitizing Drugs
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Chlorella has been reported to cause photosensitization. In five case reports, patients who had ingested chlorella exhibited swelling followed by erythematopurpuric lesions on sun-exposed areas of the body. Theoretically, concomitant use with photosensitizing drugs may exacerbate effects.
Warfarin (Coumadin)
Theoretically, chlorella might reduce the clinical effects of warfarin.
Chlorella contains significant amounts of vitamin K. There is at least one case report of warfarin therapy becoming sub-therapeutic after initiation of chlorella supplements.
Barley Grass
Triclabendazole (Egaten)
Theoretically, barley might decrease the clinical effects of triclabendazole.
Animal research suggests that a diet supplemented with barley can reduce the bioavailability of triclabendazole when taken concomitantly. This effect has not been shown in humans.
Brand information
Manufacturer and brand details for Kyo-Green Powdered Drink Mix, from the product label.
Kyo-Green
See all Kyo-Green products- Name
- Wakunaga of America Co., Ltd.
- Street Address
- 23501 Madero
- City
- Mission Viejo
- State
- CA
- ZipCode
- 92691
- Web Address
- www.kyolic.com
Kyo-Green Powdered Drink Mix by Kyo-Green: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Kyo-Green Powdered Drink Mix’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Fucus Vesiculosus
Interacts with 891 drugsFucus vesiculosus (bladderwrack) is a brown seaweed rich in iodine that has been used traditionally for thyroid concerns, weight, and skin. There is little solid human evidence to support mo...
Read the full Fucus Vesiculosus monograph → Herb & supplement monographChlorella
Interacts with 337 drugsChlorella is a nutrient-rich freshwater green algae taken as a supplement for general wellness, immune support, and 'detox.' Some small studies suggest possible benefits for cholesterol, blo...
Read the full Chlorella monograph → Herb & supplement monographBarley
Interacts with 1 drugBarley is a nutritious whole grain that is a good source of soluble fiber called beta-glucan, which has solid evidence for modestly lowering LDL ('bad') cholesterol when eaten regularly. It...
Read the full Barley monograph → Herb & supplement monographCouch Grass
Couch grass is a common lawn weed whose rhizome has long been used in traditional European herbal medicine, mainly for urinary and bladder complaints. High-quality human studies are lacking,...
Read the full Couch Grass monograph →Sources & How We Checked
Kyo-Green Powdered Drink Mix's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 43 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Fucus Vesiculosus 15 references
- Goodman GA, Rall TW, Nies AS, Taylor P. The Pharmacological Basis of Therapeutics, 9th ed.
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
- Phaneuf D, Cote I, Dumas P, et al. Evaluation of the contamination of marine algae (Seaweed) from the St. Lawrence River and likely to be consumed by humans. Environ Res 1999;80:S175-S182. PubMed
- Durig J, Bruhn T, Zurborn KH, et al. Anticoagulant fucoidan fractions from Fucus vesiculosus induce platelet activation in vitro. Thromb Res 1997;85:479-91. PubMed
- Conz PA, La Greca G, Benedetti P, et al. Fucus vesiculosus: a nephrotoxic alga? Nephrol Dial Transplant 1998;13:526-7.
- Ohye H, Fukata S, Kanoh M, et al. Thyrotoxicosis caused by weight-reducing herbal medicines. Arch Intern Med 2005;165:831-4. PubMed
- Okamura K, Inoue K, Omae T. A case of Hashimoto's thyroiditis with thyroid immunological abnormality manifested after habitual ingestion of seaweed. Acta Endocrinol (Copenh) 1978;88:703-12. PubMed
- Agarwal SC, Crook JR, Pepper CB. Herbal remedies -- how safe are they? A case report of polymorphic ventricular tachycardia/ventricular fibrillation induced by herbal medication used for obesity. Int J Cardiol 2006;106:260-1. PubMed
- Sterling JB, Heymann WR. Potassium iodide in dermatology: a 19th century drug for the 21st century-uses, pharmacology, adverse effects, and contraindications. J Am Acad Dermatol 2000;43:691-7. PubMed
- Catania, M. A., Oteri, A., Caiello, P., Russo, A., Salvo, F., Giustini, E. S., Caputi, A. P., and Polimeni, G. Hemorrhagic cystitis induced by an herbal mixture. South.Med.J. 2010;103(1):90-92. PubMed
- Cumashi, A., Ushakova, N. A., Preobrazhenskaya, M. E., D'Incecco, A., Piccoli, A., Totani, L., Tinari, N., Morozevich, G. E., Berman, A. E., Bilan, M. I., Usov, A. I., Ustyuzhanina, N. E., Grachev, A. A., Sanderson, C. J., Kelly, M., Rabinovich, G. A., I
- Irhimeh, M. R., Fitton, J. H., and Lowenthal, R. M. Pilot clinical study to evaluate the anticoagulant activity of fucoidan. Blood Coagul.Fibrinolysis 2009;20(7):607-610. PubMed
- Arbaizar, B. and Llorca, J. [Fucus vesiculosus induced hyperthyroidism in a patient undergoing concomitant treatment with lithium]. Actas Esp.Psiquiatr. 2011;39(6):401-403.
- Church FC, Meade JB, Treanor RE, and et al. Antithrombin activity of fucoidan. The interaction of fucoidan with heparin cofactor II, antithrombin III, and thrombin. J Biol Chem 2-25-1989;264(6):3618-3623. DOI
- Mathew L, Burney M, Gaikwad A, et al. Preclinical evaluation of safety of fucoidan extracts from Undaria pinnatifida and Fucus vesiculosus for use in cancer treatment. Integr Cancer Ther 2017;16(4):572-84.
Chlorella 13 references
- Peirce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York, NY: William Morrow and Co., 1999.
- Ng TP, Tan WC, Lee YK. Occupational asthma in a pharmacist induced by chlorella, a unicellular algae preparation. Resp Med 1994;88:555-7. PubMed
- Jitsukawa K, Suizu R, Hidano A. Chlorella photosensitization. New phytophotodermatosis. Int J Dermatol 1984;23:263-8. PubMed
- Merchant RE, Carmack CA, Wise CM. Nutritional supplementation with Chlorella pyrenoidosa for patients with fibromyalgia syndrome: a pilot study. Phytother Res 2000;14:167-73.
- Merchant RE, Rice CD, Young HF. Dietary Chlorella pyrenoidosa for patients with malignant glioma: effects on immunocompetence, quality of life, and survival. Phytother Res 1990;4:220-31.
- Halperin SA, Smith B, Nolan C, et al. Safety and immunoenhancing effect of a Chlorella-derived dietary supplement in healthy adults undergoing influenza vaccination: randomized, double-blind, placebo-controlled trial. CMAJ 2003;169:111-7..
- Ohtake, T., Negishi, K., Okamoto, K., Oka, M., Maesato, K., Moriya, H., and Kobayashi, S. Manganese-induced Parkinsonism in a patient undergoing maintenance hemodialysis. Am J Kidney Dis 2005;46(4):749-753. PubMed
- Ng, T. P., Tan, W. C., and Lee, Y. K. Occupational asthma in a pharmacist induced by Chlorella, a unicellular algae preparation. Respir.Med. 1994;88(7):555-557. PubMed
- Ohkawa, S., Yoneda, Y., Ohsumi, Y., and Tabuchi, M. [Warfarin therapy and chlorella]. Rinsho Shinkeigaku 1995;35(7):806-807.
- Azocar J, Diaz A. Efficacy and safety of chlorella supplementation in adults with chronic hepatitis C virus infection. World J Gastroenterol 2013;19(7):1085-90. PubMed
- Panahi Y, Badeli R, Karami GR, Badeli Z, Sahebkar A. A randomized controlled trial of 6-week Chlorella vulgaris supplementation in patients with major depressive disorder. Complement Ther Med 2015;23(4):598-602. PubMed
- Nakano S, Takekoshi H, Nakano M. Chlorella pyrenoidosa supplementation reduces the risk of anemia, proteinuria and edema in pregnant women. Plant Foods Hum Nutr 2010;65(1):25-30. PubMed
- Yavasoglu I, Turgutkaya A, Bolaman Z. Chlorella-induced thrombocytopenia. Sao Paulo Med J 2018;136(6):602-3. PubMed
Barley 15 references
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Fernandez-Anaya S, Crespo JF, Rodriguez JR, et al. Beer anaphylaxis. J Allergy Clin Immunol 1999;103:959-60.
- Lembo A, Camilleri M. Chronic constipation. N Engl J Med 2003;349:1360-8. . PubMed
- Ferre, I., Giraldez, F. J., Alvarez-Bujidos, M. L., and Mantecon, A. R. Influence of barley supplement on plasma concentration of triclabendazole metabolites in sheep. Vet.Rec. 11-22-1997;141(21):549-551. PubMed
- Curioni, A., Santucci, B., Cristaudo, A., Canistraci, C., Pietravalle, M., Simonato, B., and Giannattasio, M. Urticaria from beer: an immediate hypersensitivity reaction due to a 10- kDa protein derived from barley. Clin Exp Allergy 1999;29(3):407-413. PubMed
- Fernandez-Anaya, S., Crespo, J. F., Rodriguez, J. R., Daroca, P., Carmona, E., Herraez, L., and Lopez-Rubio, A. Beer anaphylaxis. J Allergy Clin Immunol. 1999;103(5 Pt 1):959-960.
- Cronin, E. Contact dermatitis from barley dust. Contact Dermatitis 1979;5(3):196. PubMed
- Block, G., Tse, K. S., Kijek, K., Chan, H., and Chan-Yeung, M. Baker's asthma. Studies of the cross-antigenicity between different cereal grains. Clin Allergy 1984;14(2):177-185.
- van Ketel, W. G. Immediate type allergy to malt in beer. Contact Dermatitis 1980;6(4):297-298. PubMed
- Ellis, H. J., Doyle, A. P., Day, P., Wieser, H., and Ciclitira, P. J. Demonstration of the presence of coeliac-activating gliadin-like epitopes in malted barley. Int Arch Allergy Immunol. 1994;104(3):308-310. PubMed
- Vidal, C. and Gonzalez-Quintela, A. Food-induced and occupational asthma due to barley flour. Ann Allergy Asthma Immunol. 1995;75(2):121-124.
- Gutgesell, C. and Fuchs, T. Contact urticaria from beer. Contact Dermatitis 1995;33(6):436-437. PubMed
- Baker, P. G. and Read, A. E. Oats and barley toxicity in coeliac patients. Postgrad.Med J 1976;52(607):264-268. PubMed
- Nakase, M., Usui, Y., Alvarez-Nakase, A. M., Adachi, T., Urisu, A., Nakamura, R., Aoki, N., Kitajima, K., and Matsuda, T. Cereal allergens: rice-seed allergens with structural similarity to wheat and barley allergens. Allergy 1998;53(46 Suppl):55-57. PubMed
- Pereira, F., Rafael, M., and Lacerda, M. H. Contact dermatitis from barley. Contact Dermatitis 1998;39(5):261-262. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC