Interactions on record — worth a quick check against your medications. Based on 2 of 6 ingredients. Check your meds →
Dietary supplement

Kyo-Green Greens Blend Powdered Drink Mix Ingredients & Drug Interactions

by Kyo-Green

Kyo-Green Greens Blend Powdered Drink Mix label
See full label image
Powder Category: Botanical With Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Kyo-Green Greens Blend Powdered Drink Mix against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Kyo-Green Greens Blend Powdered Drink Mix is a dietary supplement by Kyo-Green with 6 active ingredients. Its ingredients are commonly taken for high cholesterol, heart health support, blood sugar support.Based on those ingredients, 338 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Chlorella, Powder, Barley, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Kyo-Green Greens Blend Powdered Drink Mix by Kyo-Green

Ask about any prescription or over-the-counter medication and we check it for interactions with Kyo-Green Greens Blend Powdered Drink Mix by Kyo-Green — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Kyo-Green Greens Blend Powdered Drink Mix by Kyo-Green

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 6 active ingredients.
  • “Kyo-Green Powder Proprietary Blend” is a proprietary blend — the label gives one combined amount (2.50 Gram(s)) without saying how much of each component you get.

Kyo-Green contains six active ingredients: barley powder and brown rice powder as grain bases, chlorella and wheatgrass powders as nutrient-dense greens, kelp powder for minerals, and fructooligosaccharides (a prebiotic fiber). The product also contains inactive ingredients including potato starch, vitamin C, beta-carotene, licorice extract, and guar gum as binders and fillers.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Strong

Strong clinical evidence supports its ingredients for:

Why this rating?
  • The label markets general wellness (“Energy support”), not a specific health condition, so there is no single claim to grade against clinical-evidence data.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Coronary heart disease (CHD) — rated "Likely Effective" (Barley) (Natural Medicines).
  • On file: Hypercholesterolemia — rated "Likely Effective" (Barley) (Natural Medicines).
  • On file: Pregnancy-related iron deficiency — rated "Possibly Effective" (Chlorella) (Natural Medicines).

The only ingredient here with solid effectiveness evidence is barley powder, which is likely effective for lowering cholesterol and supporting coronary heart disease. The other ingredients' effectiveness isn't well established in the data we hold — chlorella shows possibly effective evidence for pregnancy-related low iron, but the rest (wheatgrass, kelp, and the others) either have insufficient evidence or we couldn't assess them.

This is a green-food blend, not a targeted treatment for any one condition.

The evidence, ingredient by ingredient Barley Chlorella

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Barley is generally well tolerated as a food, but it contains gluten — so if you're gluten-sensitive or have celiac disease, this product isn't for you. Barley can cause bloating, gas, and an unpleasant taste in some people; allergic reactions are possible in sensitive individuals.

Chlorella is generally well tolerated short-term, but product quality varies widely. It may cause digestive upset (cramping, diarrhea, gas, nausea), especially in the first two weeks, and can cause photosensitivity (sun sensitivity) in some users.

Allergic reactions including asthma and anaphylaxis have been reported, though they're rare. Safety data for pregnancy and breastfeeding hasn't been established for concentrated chlorella supplements — talk with your doctor before using if you're pregnant or nursing.

Side effects, ingredient by ingredient Barley Chlorella

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Barley, Chlorella.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 338 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications against this product if you take warfarin (Coumadin) or other blood thinners — chlorella may make them less effective. Also double-check if you're on photosensitizing drugs (ask your pharmacist if you're unsure) or if you take triclabendazole (Egaten) for a parasite infection.

Use the search tool on this page to run your exact medications through our checker.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

This is a green-food powder with some solid evidence behind barley's effect on cholesterol and heart health. If you take warfarin or a photosensitizing medication, or take triclabendazole for a parasite infection, you'll need to check with your pharmacist before starting.

If you have gluten sensitivity or celiac disease, skip it. Otherwise, most people tolerate it well, though digestive upset is common in the first couple of weeks.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Kyo-Green Greens Blend Powdered Drink Mix, straight from the product label.

Brand Kyo-Green
Barcode (UPC) 023542700504
Net contents 5.3 Ounce(s); 150 Gram(s)
Market status On market
Date entered into DSLD Jan 23, 2025
DSLD ID 326191
Product type Botanical With Nutrients
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Kyo-Green Greens Blend Powdered Drink Mix by Kyo-Green, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2.5 Gram(s)
Maximum serving Sizes:
2.5 Gram(s)
Servings per container
60
UPC/BARCODE
023542700504
IngredientAmount% DV
Brown Rice, Powder0 NP--
Barley, Powder0 NP--
Kelp, Powder0 NP--
Chlorella, Powder0 NP--
Wheatgrass, Powder0 NP--
Kyo-Green Powder Proprietary Blend2.5 Gram(s)--
Fructooligosaccharides0 NP--

Other ingredients: Potato Starch, Vitamin C, Beta-Carotene, Licorice Extract, Guar Gum

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Energy

GMO free Gluten free

Vegan

Free of: GMOs, soy, gluten, dairy, tree nuts, sodium, yeast, artificial colors and flavors.

Suitable for vegans.

Seals/Symbols

Vegan

Formula

Barley grass, wheat grass & chlorella

Kyo-Green Powdered Drink Mix contains a unique blend of superfoods that provide balanced nutritional benefits for the whole body. Barely grass and wheat grass grown in Japan's pristine highlands encourage a strong immune response and sustained energy. Brown rice and FOS (from chicory root) promote healthy digestion. Chlorella and kelp's unique nutrient composition supports heart health.

FDA Statement of Identity

Nutritional Supplement

Suggested/Recommended/Usage/Directions

Suggested use: Mix one teaspoon of powder with six to eight ounces (one cup) of juice or water daily.

Mix one serving of fast dissolving Kyo-Green powder with water or fruit juice, or add to your favorite smoothie. Stir, enjoy and get going!

Storage

Store in a cool, dry place with cap tight. Keep away from direct light.

Precautions

Keep out of reach of children.

Glass bottle inside. Handle with care.

Safety sealed: Do not use if inner seal is broken or missing.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Kyo-Green Greens Blend Powdered Drink Mix by Kyo-Green label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Kyo-Green Greens Blend Powdered Drink Mix label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Kyo-Green Greens Blend Powdered Drink Mix by Kyo-Green

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size2.5 Gram(s) Dosage formPowder Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Kyo-Green Powder Proprietary Blend

2.5 Gram(s) per serving

Other (inactive) ingredients: Potato Starch, Vitamin C, Beta-Carotene, Licorice Extract, Guar Gum. These complete the product’s ingredient list but are not active constituents.

Interaction report

Kyo-Green Greens Blend Powdered Drink Mix by Kyo-Green Drug Interactions

Want to check YOUR meds against Kyo-Green Greens Blend Powdered Drink Mix?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
338Drugs
338 Moderate

Ingredients driving the most interactions

Chlorella, Powder 337
Barley, Powder 1

Individual Drug Interactions

The ingredients in Kyo-Green Greens Blend Powdered Drink Mix interact with 338 drugs. Click any drug to see the details.

2 of the 6 ingredients in Kyo-Green Greens Blend Powdered Drink Mix interact with drugs. Each result below shows which ingredient is responsible. Chlorella, Powder Barley, Powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Kyo-Green Greens Blend Powdered Drink Mix with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Chlorella, Powder2 drug types · 337 drugs

Photosensitizing Drugs

Theoretically, chlorella might have additive effects with photosensitizing drugs.
Chlorella has been reported to cause photosensitization. In five case reports, patients who had ingested chlorella exhibited swelling followed by erythematopurpuric lesions on sun-exposed areas of the body. Theoretically, concomitant use with photosensitizing drugs may exacerbate effects.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, chlorella might reduce the clinical effects of warfarin.
Chlorella contains significant amounts of vitamin K. There is at least one case report of warfarin therapy becoming sub-therapeutic after initiation of chlorella supplements.

Likelihood Possible Evidence D
Chlorella, Powder full monograph & interactions

Barley, Powder1 drug type · 1 drug

Triclabendazole (Egaten)

Theoretically, barley might decrease the clinical effects of triclabendazole.
Animal research suggests that a diet supplemented with barley can reduce the bioavailability of triclabendazole when taken concomitantly. This effect has not been shown in humans.

Likelihood Possible Evidence D
Barley, Powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Kyo-Green Greens Blend Powdered Drink Mix, from the product label.

Kyo-Green

See all Kyo-Green products
Name
Wakunaga of America Co., Ltd.
City
Mission Viejo
State
CA
ZipCode
92691
Phone Number
(800) 421.2998
Web Address
www.kyolic.com
Pharmacist Counseling Corner

Kyo-Green Greens Blend Powdered Drink Mix by Kyo-Green: Common Questions

Does Kyo-Green Greens Blend Powdered Drink Mix by Kyo-Green interact with any medications?
Yes. Based on its ingredients, Kyo-Green Greens Blend Powdered Drink Mix has a known interaction with 338 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Kyo-Green Greens Blend Powdered Drink Mix contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this have gluten in it?
Yes — barley powder is one of the main ingredients, and barley contains gluten. If you're gluten-sensitive or have celiac disease, this product isn't safe for you.
Can I take this while pregnant or breastfeeding?
The safety data for concentrated chlorella supplements in pregnancy and breastfeeding hasn't been established. Barley as a regular food is fine, but concentrated barley supplements also aren't well studied during pregnancy and breastfeeding. Talk with your doctor or pharmacist before using this product if you're pregnant or nursing — they can give you personalized advice based on your situation.
Will this lower my cholesterol?
Barley powder, which is in this blend, is likely effective for lowering cholesterol and supporting heart health. The other ingredients don't have the same level of evidence behind them for this purpose.
What kind of side effects might I get?
Most people tolerate it well, but digestive upset is common in the first couple of weeks — bloating, gas, diarrhea, or cramping. Some people may experience nausea. Barley can cause an unpleasant taste. Allergic reactions are possible in sensitive individuals. Chlorella can also increase your skin's sensitivity to sunlight.
How much vitamin K is in this?
We don't have the exact amount on file. If you take warfarin or another blood thinner, that's important information — ask your pharmacist or the product maker directly before you start.
Is this product tested for quality and purity?
Product quality and purity of chlorella supplements vary widely. The data we hold notes this as a caution. If purity is important to you, check the label for third-party testing or ask the maker about their testing standards.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Kyo-Green Greens Blend Powdered Drink Mix is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Kyo-Green Greens Blend Powdered Drink Mix label
Go deeper

The Full Monographs Behind Kyo-Green Greens Blend Powdered Drink Mix’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Barley

Interacts with 1 drug

Barley is a nutritious whole grain that is a good source of soluble fiber called beta-glucan, which has solid evidence for modestly lowering LDL ('bad') cholesterol when eaten regularly. It...

Read the full Barley monograph → Herb & supplement monograph

Chlorella

Interacts with 337 drugs

Chlorella is a nutrient-rich freshwater green algae taken as a supplement for general wellness, immune support, and 'detox.' Some small studies suggest possible benefits for cholesterol, blo...

Read the full Chlorella monograph →
Sources

Sources & How We Checked

Kyo-Green Greens Blend Powdered Drink Mix's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 28 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Barley 15 references
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Fernandez-Anaya S, Crespo JF, Rodriguez JR, et al. Beer anaphylaxis. J Allergy Clin Immunol 1999;103:959-60.
  3. Lembo A, Camilleri M. Chronic constipation. N Engl J Med 2003;349:1360-8. . PubMed
  4. Ferre, I., Giraldez, F. J., Alvarez-Bujidos, M. L., and Mantecon, A. R. Influence of barley supplement on plasma concentration of triclabendazole metabolites in sheep. Vet.Rec. 11-22-1997;141(21):549-551. PubMed
  5. Curioni, A., Santucci, B., Cristaudo, A., Canistraci, C., Pietravalle, M., Simonato, B., and Giannattasio, M. Urticaria from beer: an immediate hypersensitivity reaction due to a 10- kDa protein derived from barley. Clin Exp Allergy 1999;29(3):407-413. PubMed
  6. Fernandez-Anaya, S., Crespo, J. F., Rodriguez, J. R., Daroca, P., Carmona, E., Herraez, L., and Lopez-Rubio, A. Beer anaphylaxis. J Allergy Clin Immunol. 1999;103(5 Pt 1):959-960.
  7. Cronin, E. Contact dermatitis from barley dust. Contact Dermatitis 1979;5(3):196. PubMed
  8. Block, G., Tse, K. S., Kijek, K., Chan, H., and Chan-Yeung, M. Baker's asthma. Studies of the cross-antigenicity between different cereal grains. Clin Allergy 1984;14(2):177-185.
  9. van Ketel, W. G. Immediate type allergy to malt in beer. Contact Dermatitis 1980;6(4):297-298. PubMed
  10. Ellis, H. J., Doyle, A. P., Day, P., Wieser, H., and Ciclitira, P. J. Demonstration of the presence of coeliac-activating gliadin-like epitopes in malted barley. Int Arch Allergy Immunol. 1994;104(3):308-310. PubMed
  11. Vidal, C. and Gonzalez-Quintela, A. Food-induced and occupational asthma due to barley flour. Ann Allergy Asthma Immunol. 1995;75(2):121-124.
  12. Gutgesell, C. and Fuchs, T. Contact urticaria from beer. Contact Dermatitis 1995;33(6):436-437. PubMed
  13. Baker, P. G. and Read, A. E. Oats and barley toxicity in coeliac patients. Postgrad.Med J 1976;52(607):264-268. PubMed
  14. Nakase, M., Usui, Y., Alvarez-Nakase, A. M., Adachi, T., Urisu, A., Nakamura, R., Aoki, N., Kitajima, K., and Matsuda, T. Cereal allergens: rice-seed allergens with structural similarity to wheat and barley allergens. Allergy 1998;53(46 Suppl):55-57. PubMed
  15. Pereira, F., Rafael, M., and Lacerda, M. H. Contact dermatitis from barley. Contact Dermatitis 1998;39(5):261-262. PubMed

See these in context on the Barley monograph →

Chlorella 13 references
  1. Peirce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York, NY: William Morrow and Co., 1999.
  2. Ng TP, Tan WC, Lee YK. Occupational asthma in a pharmacist induced by chlorella, a unicellular algae preparation. Resp Med 1994;88:555-7. PubMed
  3. Jitsukawa K, Suizu R, Hidano A. Chlorella photosensitization. New phytophotodermatosis. Int J Dermatol 1984;23:263-8. PubMed
  4. Merchant RE, Carmack CA, Wise CM. Nutritional supplementation with Chlorella pyrenoidosa for patients with fibromyalgia syndrome: a pilot study. Phytother Res 2000;14:167-73.
  5. Merchant RE, Rice CD, Young HF. Dietary Chlorella pyrenoidosa for patients with malignant glioma: effects on immunocompetence, quality of life, and survival. Phytother Res 1990;4:220-31.
  6. Halperin SA, Smith B, Nolan C, et al. Safety and immunoenhancing effect of a Chlorella-derived dietary supplement in healthy adults undergoing influenza vaccination: randomized, double-blind, placebo-controlled trial. CMAJ 2003;169:111-7..
  7. Ohtake, T., Negishi, K., Okamoto, K., Oka, M., Maesato, K., Moriya, H., and Kobayashi, S. Manganese-induced Parkinsonism in a patient undergoing maintenance hemodialysis. Am J Kidney Dis 2005;46(4):749-753. PubMed
  8. Ng, T. P., Tan, W. C., and Lee, Y. K. Occupational asthma in a pharmacist induced by Chlorella, a unicellular algae preparation. Respir.Med. 1994;88(7):555-557. PubMed
  9. Ohkawa, S., Yoneda, Y., Ohsumi, Y., and Tabuchi, M. [Warfarin therapy and chlorella]. Rinsho Shinkeigaku 1995;35(7):806-807.
  10. Azocar J, Diaz A. Efficacy and safety of chlorella supplementation in adults with chronic hepatitis C virus infection. World J Gastroenterol 2013;19(7):1085-90. PubMed
  11. Panahi Y, Badeli R, Karami GR, Badeli Z, Sahebkar A. A randomized controlled trial of 6-week Chlorella vulgaris supplementation in patients with major depressive disorder. Complement Ther Med 2015;23(4):598-602. PubMed
  12. Nakano S, Takekoshi H, Nakano M. Chlorella pyrenoidosa supplementation reduces the risk of anemia, proteinuria and edema in pregnant women. Plant Foods Hum Nutr 2010;65(1):25-30. PubMed
  13. Yavasoglu I, Turgutkaya A, Bolaman Z. Chlorella-induced thrombocytopenia. Sao Paulo Med J 2018;136(6):602-3. PubMed

See these in context on the Chlorella monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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