Interactions on record — worth a quick check against your medications. Based on 4 of 6 ingredients. Check your meds →
Dietary supplement

L-Carnitine 1500 Grape Crush Ingredients & Drug Interactions

by NutraKey Health Performance

L-Carnitine 1500 Grape Crush label
See full label image
Liquid Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking L-Carnitine 1500 Grape Crush against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

L-Carnitine 1500 Grape Crush is a dietary supplement by NutraKey Health Performance with 6 active ingredients. Its ingredients are commonly taken for morning sickness in pregnancy, premenstrual syndrome (pms), preventing or treating b6 deficiency.Based on those ingredients, 413 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vitamin B6, Acetyl L-Carnitine, L-Carnitine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against L-Carnitine 1500 Grape Crush by NutraKey Health Performance

Ask about any prescription or over-the-counter medication and we check it for interactions with L-Carnitine 1500 Grape Crush by NutraKey Health Performance — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of L-Carnitine 1500 Grape Crush by NutraKey Health Performance

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 2 of its 5 active ingredients.
  • “L-Carnitine, Acetyl L-Carnitine, L-Carnitine-L-Tartrate” is listed as a grouped ingredient — the label gives one combined amount (1,500 mg) without saying how much of each component you get.

L-Carnitine 1500 Grape Crush contains five active ingredients. Three of them are carnitine compounds: L-carnitine, acetyl L-carnitine, and L-carnitine-L-tartrate — they're related forms that support energy production in your cells.

You'll also find vitamin B6 (needed for brain and nerve function) and pantothenic acid (a B vitamin that plays a role in metabolism). The rest is inactive ingredients — water, glycerin, citric acid, flavoring, malic acid, sucralose, and potassium sorbate — which are fillers, flavor enhancers, and preservatives that help the liquid stay stable.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: weight loss energy and fat burning.
  • We looked for evidence on: Athletic performance, Cancer-related fatigue, Chronic fatigue syndrome (CFS), Metabolism, Fat oxidation, Exercise performance — and 1 related terms.
  • The closest evidence on file: Acetyl-l-carnitine is rated "Insufficient Reliable Evidence To Rate" for Athletic performance (Natural Medicines).
  • Also on file: Acetyl-l-carnitine is rated "Insufficient Reliable Evidence To Rate" for Cancer-related fatigue, Chronic fatigue syndrome (CFS).
  • Also on file: Pantothenic Acid is rated "Insufficient Reliable Evidence To Rate" for Athletic performance, Chronic fatigue syndrome (CFS).

The carnitine forms in this product are effective for treating L-carnitine deficiency and possibly effective for high cholesterol, congestive heart failure, and angina. Acetyl L-carnitine is possibly effective for age-related cognitive decline, Alzheimer's disease, alcohol use disorder, diabetic neuropathy, and depression.

Vitamin B6 is effective for treating vitamin B6 deficiency, sideroblastic anemia, and pyridoxine-dependent epilepsy; it's likely effective for high homocysteine and possibly effective for pregnancy-related nausea and vomiting. Pantothenic acid is effective for pantothenic acid deficiency, but the evidence isn't established for most other uses we hold data on.

The evidence, ingredient by ingredient Vitamin B6 Pantothenic Acid L-carnitine Acetyl-l-carnitine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vitamin B6 is well tolerated in doses below 100 mg daily, but high doses over time can damage nerves — doses exceeding 1,000 mg daily carry the most risk, though neuropathy can occur at lower amounts too. The most common side effects from vitamin B6 are abdominal pain, headache, heartburn, nausea, and vomiting.

Pantothenic acid is generally well tolerated; common side effects are minimal, though diarrhea has been reported orally. The L-carnitine forms are well tolerated but can cause stomach upset (nausea, diarrhea, abdominal pain, heartburn), reduced appetite, and a fishy-smelling body odor.

Seizures are rare. Acetyl L-carnitine may also cause agitation, dry mouth, headache, and insomnia.

For pregnancy, vitamin B6 is likely safe but also rated possibly unsafe — talk with your doctor. Pantothenic acid is likely safe in pregnancy.

L-carnitine pregnancy safety data isn't on file — ask your pharmacist. For breastfeeding, vitamin B6 and pantothenic acid are likely safe; L-carnitine and L-carnitine-L-tartrate are possibly safe; acetyl L-carnitine safety while breastfeeding is unknown, so it's best avoided unless your doctor advises otherwise.

Side effects, ingredient by ingredient Vitamin B6 Pantothenic Acid L-carnitine Acetyl-l-carnitine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 4 matched ingredients can interact with medications — Acetyl-l-carnitine, Vitamin B6, L-carnitine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; Parkinson's medications.
  • For scale: 413 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Moderate-severity interactions: if you take blood thinners (warfarin, acenocoumarol), check first — the carnitine forms may increase bleeding risk. Also check if you're on blood pressure medications, thyroid hormone replacement, seizure medications, or antidepressants — vitamin B6 and the carnitine compounds can affect how these work.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product may help with L-carnitine deficiency and possibly support heart health and cholesterol levels. If you take blood thinners, thyroid medication, seizure drugs, blood pressure meds, or antidepressants, check with us before starting — several ingredients interact with these.

Pregnancy or breastfeeding? Talk to your pharmacist about vitamin B6 and acetyl L-carnitine first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about L-Carnitine 1500 Grape Crush, straight from the product label.

Brand NutraKey Health Performance
Barcode (UPC) 820103980074
Net contents 16 Fluid Ounce(s)
Market status On market
Date entered into DSLD Jun 22, 2023
DSLD ID 287410
Product type Other Combinations
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for L-Carnitine 1500 Grape Crush by NutraKey Health Performance , sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.33 Capful(s)
Maximum serving Sizes:
0.33 Capful(s)
Servings per container
31
UPC/BARCODE
820103980074
IngredientAmount% DV
Calories0 Calorie(s)--
Total Carbohydrates0 NP--
Sugar0 NP--
Vitamin B62 mg100%
Total Fat0 NP--
Pantothenic Acid10 mg100%
L-Carnitine0 NP--
Acetyl L-Carnitine0 NP--
L-Carnitine-L-Tartrate0 NP--
L-Carnitine, Acetyl L-Carnitine, L-Carnitine-L-Tartrate1500 mg--

Other ingredients: Water, Glycerin, Citric Acid, Natural & Artificial Flavors, Malic Acid, Sucralose, Potassium Sorbate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Accelerate your weight loss Boost energy and fat burning Enhanced fat metabolism

Convert stored fat to energy Energy stored as fat Carnitine shuttles fat cells to mitochondria Mitochondria converts fat into energy Increased fat burning & energy

Stimulant free fat burn

Energy & metabolism Boost endurance Healthy energy Support fat burning

Non GMO Gluten free Dye free Paraben free

Formula

L-Carnitine is an amino acid responsible for shuttling fatty acids into the mitochondria for energy production. Enhanced mitochondrial activity results in an increase in clean energy and a boost to fat burning.

L-Carnitine can be a stimulant-free source of energy that supports increased fatty acid metabolism. Carnitine is a great alternative to synthetic fat burners that rely on stimulant-heavy formulas for increased metabolism.

Active dose Our L-Carnitine contains a biologically active dose of 1500mg per serving. Although low levels of carnitine can be found in a number of natural sources, at threshold dosage must be met to experience the performance enhancing benefits of L-Carnitine.

Grape crush natural & artificial flavors

General Statements

Achieve your goals

BPA free

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FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Recommended Use Female Up to 145lbs. 1-3 servings per day Over 145lbs. 2-4 servings per day Male Up to 145lbs. 1-3 servings per day Over 145lbs. 2-4 servings per day When to take Mornings Get a boost of clean energy by taking 1 serving in the morning, or add another serving when you need and extra boost. Training Support fat metabolism & endurance during training by taking 1 serving immediately before training. Add another serving after training for an energy boost. Meals Provide support for healthy food metabolism by taking 1 serving with your meals.

For best results: Combine with TRU Burn to further support energy & fat metabolism.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Brand IP Statement(s)

NutraKey Health for every lifestyle

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

L-Carnitine 1500 Grape Crush by NutraKey Health Performance label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

L-Carnitine 1500 Grape Crush label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in L-Carnitine 1500 Grape Crush by NutraKey Health Performance

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size0.33 Capful(s) Dosage formLiquid Servings per container31 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sugar

0 NP per serving

Vitamin B6

Interacts with
210 drugs
2 mg per serving Form: Pyridoxine Hydrochloride

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is b...

Vitamin B6 monograph & interactions

Pantothenic Acid

No known
interactions
10 mg per serving Form: Vitamin B5

Pantothenic acid is vitamin B5, an essential nutrient your body uses to turn food into energy. True deficiency is very rare because it is found in nea...

Pantothenic Acid monograph & interactions

L-Carnitine, Acetyl L-Carnitine, L-Carnitine-L-Tartrate

1500 mg per serving

Other (inactive) ingredients: Water, Glycerin, Citric Acid, Natural & Artificial Flavors, Malic Acid, Sucralose, Potassium Sorbate. These complete the product’s ingredient list but are not active constituents.

Interaction report

L-Carnitine 1500 Grape Crush by NutraKey Health Performance Drug Interactions

Want to check YOUR meds against L-Carnitine 1500 Grape Crush?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
413Drugs
408 Moderate 5 Minor

Ingredients driving the most interactions

Vitamin B6 210
Acetyl L-Carnitine 203
L-Carnitine 19

Individual Drug Interactions

The ingredients in L-Carnitine 1500 Grape Crush interact with 413 drugs. Click any drug to see the details.

3 of the 6 ingredients in L-Carnitine 1500 Grape Crush interact with drugs. Each result below shows which ingredient is responsible. Vitamin B6 Acetyl L-Carnitine L-Carnitine

Each ingredient & the kinds of drugs it affects

For each ingredient in L-Carnitine 1500 Grape Crush with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin B65 drug types · 210 drugs

Amiodarone (Cordarone)

Theoretically, vitamin B6 might increase the photosensitivity caused by amiodarone.
Despite initial case reports suggesting that pyridoxine may have a protective effect against amiodarone-induced photosensitivity, preliminary clinical research suggests that pyridoxine may actually exacerbate this adverse effect.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Research in hypertensive rats shows that vitamin B6 can decrease systolic blood pressure. Similarly, clinical research in patients with hypertension shows that taking high doses of vitamin B6 may reduce systolic and diastolic blood pressure, possibly by reducing plasma levels of epinephrine and norepinephrine.

Likelihood Possible Evidence B
Phenobarbital (Luminal)

High doses of vitamin B6 may reduce the levels and clinical effects of phenobarbital.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenobarbital, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenobarbital to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Phenytoin (Dilantin)

High doses of vitamin B6 may reduce the levels and clinical effects of phenytoin.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenytoin, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenytoin to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Levodopa

Vitamin B6 may increase the metabolism of levodopa when taken alone, but not when taken in conjunction with carbidopa.
Vitamin B6 (pyridoxine) enhances the metabolism of levodopa, reducing its clinical effects. However, this interaction does not occur when carbidopa is used concurrently with levodopa (Sinemet). Therefore, it is not likely to be a problem in most people.

Likelihood Unlikely Evidence D
Vitamin B6 full monograph & interactions

Acetyl L-Carnitine4 drug types · 203 drugs

Acenocoumarol (Sintrom)

Theoretically, acetyl-L-carnitine might increase the anticoagulant effects of acenocoumarol.
L-carnitine, the parent compound of acetyl-L-carnitine, might enhance the anticoagulant effects of acenocoumarol, an oral anticoagulant that is similar to warfarin, but shorter-acting. There are at least two case reports of INR elevation when L-carnitine was taken with acenocoumarol. In one case, a 33-year-old male with a previously stable INR had an elevated INR of 4.65 after L-carnitine was started and continued for 10 weeks. INR normalized after discontinuation of the L-carnitine-containing product. It is unclear if such an interaction would also occur with acetyl-L-carnitine.

Likelihood Possible Evidence D
Serotonergic Drugs

Theoretically, acetyl-L-carnitine might increase the risk of serotonergic side effects, including serotonin syndrome and cerebral vasoconstrictive disorders, when taken with serotonergic drugs.
Animal research shows that acetyl-L-carnitine can increase levels of serotonin in the brain.

Likelihood Possible Evidence D
Thyroid Hormone

Theoretically, acetyl-L-carnitine might decrease the effectiveness of thyroid hormone replacement.
L-carnitine appears to act as a peripheral thyroid hormone antagonist by inhibiting entry of thyroid hormone into the nucleus of cells. Taking L-carnitine also seems to diminish some of the symptoms of hyperthyroidism. It is unclear if such an interaction would occur with acetyl-L-carnitine.

Likelihood Probable Evidence B
Warfarin (Coumadin)

Theoretically, acetyl-L-carnitine might increase the anticoagulant effects of warfarin.
L-carnitine, the parent compound of acetyl-L-carnitine, might increase the anticoagulant effects of acenocoumarol, a shorter-acting oral anticoagulant similar to warfarin. There is not enough information to know whether this interaction occurs with acetyl-L-carnitine and warfarin.

Likelihood Possible Evidence D
Acetyl L-Carnitine full monograph & interactions

L-Carnitine3 drug types · 19 drugs

Acenocoumarol (Sintrom)

Theoretically, L-carnitine might increase the anticoagulant effects of acenocoumarol.
L-carnitine might enhance the anticoagulant effects of acenocoumarol, an oral anticoagulant similar to warfarin, but shorter-acting. There are at least two case reports of INR elevation with concomitant use. In one case, a 33-year-old male with a previously stable INR had an elevated INR of 4.65 after L-carnitine was started and continued for 10 weeks. INR normalized after discontinuation of the L-carnitine-containing product.

Likelihood Possible Evidence D
Thyroid Hormone

Theoretically, L-carnitine might decrease the effectiveness of thyroid hormone replacement.
L-carnitine appears to act as a peripheral thyroid hormone antagonist by inhibiting entry of thyroid hormone into the nucleus of cells. Taking L-carnitine also seems to diminish some of the symptoms of hyperthyroidism.

Likelihood Probable Evidence B
Warfarin (Coumadin)

Theoretically, L-carnitine might increase the anticoagulant effects of warfarin.
L-carnitine might increase the anticoagulant effects of acenocoumarol, a shorter-acting oral anticoagulant similar to warfarin. There is not enough information to know whether this interaction occurs with L-carnitine and warfarin.

Likelihood Possible Evidence D
L-Carnitine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for L-Carnitine 1500 Grape Crush, from the product label.

NutraKey Health Performance

See all NutraKey Health Performance products
Name
Nutakey
Street Address
975 Bennett Drive
City
Longwood
State
FL
ZipCode
32750
Web Address
nutrakeyhealth.com
Pharmacist Counseling Corner

L-Carnitine 1500 Grape Crush by NutraKey Health Performance : Common Questions

Does L-Carnitine 1500 Grape Crush by NutraKey Health Performance interact with any medications?
Yes. Based on its ingredients, L-Carnitine 1500 Grape Crush has a known interaction with 413 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
L-Carnitine 1500 Grape Crush contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What's the carnitine in this product for?
Carnitine helps your cells make energy. It's effective for treating L-carnitine deficiency and possibly helps with heart health, high cholesterol, chest pain (angina), and heart failure. Acetyl L-carnitine may also help with brain health and mood.
Is this safe to use while I'm pregnant?
Vitamin B6 in this product is likely safe but also rated possibly unsafe in pregnancy — talk with your doctor before taking it. We don't have enough safety data on the other ingredients during pregnancy, so check with your pharmacist for personalized advice.
Can I take this while breastfeeding?
Vitamin B6 and pantothenic acid are likely safe while breastfeeding. The L-carnitine and L-carnitine-L-tartrate are possibly safe, but acetyl L-carnitine safety isn't well established — it's best avoided unless your doctor says otherwise.
What side effects should I expect?
Most common are stomach issues — nausea, diarrhea, abdominal pain, heartburn — and loss of appetite. A fish-like body odor has been reported. Acetyl L-carnitine may also cause agitation, dry mouth, headache, and insomnia. These are usually mild, but high doses of the B vitamins or carnitine can cause more serious effects over time.
Does vitamin B6 really do anything at the dose in this product?
Vitamin B6 is effective for B6 deficiency, certain types of anemia, and a rare form of epilepsy. It's likely effective for high homocysteine and possibly effective for pregnancy nausea. Whether it helps at any particular dose depends on what you're using it for — that's a conversation for your pharmacist.
I heard L-carnitine can cause a fishy smell. Is that a real thing?
Yes — a fish-like body odor from the mouth, sweat, and urine has been reported with L-carnitine. It's not dangerous, but it's a known side effect worth knowing about.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

L-Carnitine 1500 Grape Crush label
Go deeper

The Full Monographs Behind L-Carnitine 1500 Grape Crush’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin B6

Interacts with 210 drugs

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is best known for helping with pregnancy-rel...

Read the full Vitamin B6 monograph → Herb & supplement monograph

Pantothenic Acid

Pantothenic acid is vitamin B5, an essential nutrient your body uses to turn food into energy. True deficiency is very rare because it is found in nearly all foods, and most people meet thei...

Read the full Pantothenic Acid monograph → Herb & supplement monograph

L-carnitine

Interacts with 19 drugs

L-carnitine is a compound your body makes naturally and also gets from foods like meat. It helps cells turn fat into energy, and supplements are most clearly useful for people with a true ca...

Read the full L-carnitine monograph → Herb & supplement monograph

Acetyl-l-carnitine

Interacts with 203 drugs

Acetyl-L-carnitine is a form of the amino acid carnitine that the body uses to help produce energy in cells. It is most studied for nerve pain and memory-related conditions, though the evide...

Read the full Acetyl-l-carnitine monograph →
Sources

Sources & How We Checked

L-Carnitine 1500 Grape Crush's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 106 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin B6 32 references
  1. Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
  2. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  3. Geerling BJ, Dagnelie PC, Badart-Smook A, et al. Diet as a risk factor for the development of ulcerative colitis. Am J Gastroenterol 2000;95:1008-13. PubMed
  4. South M. Neonatal seizures after pyridoxine use -- reply. Lancet 1999;354:2083. PubMed
  5. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  6. Baxter P, Aicardi J. Neonatal seizures after pyridoxine use. Lancet 1999;354:2082-3. PubMed
  7. Bendich A, Cohen M. Vitamin B6 safety issues. Ann N Y Acad Sci 1990;585:321-30.
  8. Schaumburg H, Kaplan J, Windebank A. Sensory neuropathy from pyridoxine abuse. A new megavitamin syndrome. N Engl J Med 1983;309:445-8. PubMed
  9. Gordon N. Pyridoxine dependency: an update. Dev Med Child Neurol 1997;39:63-5. PubMed
  10. Lewis PJ. Pain in the hand and wrist. Pyridoxine supplements may help patients with carpal tunnel syndrome. BMJ 1995;310:1534. PubMed
  11. Kaufman G. Pyridoxine against amiodarone-induced photosensitivity (letter). Lancet 1984;1:51-2. PubMed
  12. Mulrow JP, Mulrow CD, McKenna WJ. Pyridoxine and amiodarone-induced photosensitivity. Ann Intern Med 1985;103:68-9. PubMed
  13. Kawada A, Kashima A, Shiraishi H, et al. Pyridoxine-induced photosensitivity and hypophosphatasia. Dermatology 2000;201:356-60.. PubMed
  14. Vasile A, Goldberg R, Kornberg B. Pyridoxine toxicity: report of a case. J Am Osteopath Assoc 1984;83:790-1. DOI
  15. Hansson O, Sillanpaa M. Pyridoxine and serum concentration of phenytoin and phenobarbitone. Lancet 1976;1:256. DOI
  16. Jansen T, Romiti R, Kreuter A, Altmeyer P. Rosacea fulminans triggered by high-dose vitamins B6 and B12. J Eur Acad Dermatol Venereol 2001;15:484-5..
  17. Chittumma P, Kaewkiattikun K, Wiriyasiriwach B. Comparison of the effectiveness of ginger and vitamin B6 for treatment of nausea and vomiting in early pregnancy: a randomized double-blind controlled trial. J Med Assoc Thai 2007;90:15-20.
  18. Hatzitolios, A., Iliadis, F., Katsiki, N., and Baltatzi, M. Is the anti-hypertensive effect of dietary supplements via aldehydes reduction evidence based? A systematic review. Clin Exp.Hypertens. 2008;30(7):628-639. PubMed
  19. Vasdev, S., Ford, C. A., Parai, S., Longerich, L., and Gadag, V. Dietary vitamin B6 supplementation attenuates hypertension in spontaneously hypertensive rats. Mol.Cell Biochem. 1999;200(1-2):155-162.
  20. de, Vogel S., Dindore, V., van, Engeland M., Goldbohm, R. A., van den Brandt, P. A., and Weijenberg, M. P. Dietary folate, methionine, riboflavin, and vitamin B-6 and risk of sporadic colorectal cancer. J Nutr 2008;138(12):2372-2378. PubMed
  21. Hagen, I., Nesheim, B. I., and Tuntland, T. No effect of vitamin B-6 against premenstrual tension. A controlled clinical study. Acta Obstet.Gynecol.Scand. 1985;64(8):667-670. PubMed
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Pantothenic Acid 11 references
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L-carnitine 41 references
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Acetyl-l-carnitine 22 references
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