Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Lacidofil Ingredients & Drug Interactions

by XYMOGEN

Lacidofil label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Lacidofil against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Lacidofil is a dietary supplement by XYMOGEN with 2 active ingredients. Its ingredients are commonly taken for mood and stress support, digestive and gut health, sleep support.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lactobacillus helveticus Rosell-52. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Lacidofil by XYMOGEN

Ask about any prescription or over-the-counter medication and we check it for interactions with Lacidofil by XYMOGEN — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Lacidofil by XYMOGEN

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 13, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 2 active ingredients.
  • “Lacidofil Blend” is a proprietary blend — the label gives one combined amount (49.40 mg) without saying how much of each component you get.

Lacidofil is a two-ingredient probiotic capsule. It contains Lactobacillus rhamnosus Rosell-11 and Lactobacillus helveticus Rosell-52 — both live bacterial strains meant to support gut health.

The inactive ingredients are maltodextrin, gelatin, magnesium stearate, and ascorbic acid, which help form and preserve the capsule.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Lactobacillus Helveticus product and its label doesn't state a use — see Lactobacillus Helveticus's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for Lactobacillus helveticus isn't well established yet for the conditions we have data on — including hay fever, antibiotic-associated diarrhea, cognitive function, depression, rotaviral diarrhea, and exercise-induced respiratory infections. We hold insufficient reliable evidence to rate any of these uses.

That doesn't mean it doesn't work; it means large, rigorous trials haven't been done to prove it clearly. Talk with your doctor about whether it makes sense for what you're hoping to address.

The evidence, ingredient by ingredient Lactobacillus Helveticus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactobacillus helveticus is generally well tolerated in healthy people, though people who are seriously ill or immunocompromised should be cautious — it's a live organism, and safety data are limited. Since these capsules contain live, active bacteria, there's a small theoretical concern that they might cause infection in some patients, particularly those with certain medical conditions.

The product labeling advises using it only with your doctor's guidance, so check in before starting.

Side effects, ingredient by ingredient Lactobacillus Helveticus

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Lactobacillus Helveticus.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Lacidofil, check with your doctor or pharmacist if you're on antibiotic drugs — taking them at the same time as this product may reduce the probiotic's effectiveness. Altogether, these interactions span 182 individual medications.

If you're on any other regular prescriptions, run them through the medication checker on this page to be sure.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Lacidofil is a two-strain probiotic meant for people interested in supporting their gut health. If you're on antibiotics, timing matters — spacing out when you take them and this supplement can help.

Because safety data are limited and the strains are live organisms, talk with your doctor or pharmacist before starting, especially if you have any serious illness or immune system issues.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 22, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lacidofil, straight from the product label.

Brand XYMOGEN
Barcode (UPC) 871149000233
Net contents 84 Capsule(s)
Market status On market
Date entered into DSLD Oct 22, 2016
DSLD ID 66145
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lacidofil by XYMOGEN, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
42
UPC/BARCODE
871149000233
IngredientAmount% DV
Lactobacillus rhamnosus Rosell-110 NP--
Lacidofil Blend49.4 mg--
Lactobacillus helveticus Rosell-520 NP--

Other ingredients: Maltodextrin, Gelatin, Magnesium Stearate, Ascorbic Acid

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: Take one to two capsules one to three times a day, or as directed by your healthcare practitioner.

Precautions

Consult your healthcare practitioner prior to use, especially if you are severely immunosuppressed.

Individuals taking medication should discuss potential interactions with their healthcare practitioner.

Do not use if tamper seal is damaged.

Storage: Keep refrigerated and out of reach of children.

Contains: Milk and Soy.

Formula

Lacidofil features Institut Rosell's Lactobacillus helveticus and Lactobacillus rhamnosus.

Contains: Milk and Soy.

General Statements

Both of these strains have been extensively studied in human clinical trials, possess an excellent proliferation index, and have demonstrated beneficial impacts on human health

Probiotics Institut Rosell

Proprietary Probiotic Blend

ePV: Exclusive Professional Formulas

This package is completely recyclable Scan To Learn More!

Professional Use Only

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration.This product is not intended to diagnose, treat, cure, or prevent any disease.

Storage

Storage: Keep refrigerated and out of reach of children.

Formulation

Does Not Contain: Wheat, gluten, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, or artificial preservatives.

General

ZLB-LACIDDF-02 REV. 121415

Brand IP Statement(s)

2015 Xymogen

Not for resale on third-party websites, including, but not limited to, Amazon and eBay.

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Third-Party GMP Compliant Verified

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Lacidofil by XYMOGEN label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Lacidofil label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Lacidofil by XYMOGEN

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container42 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Lacidofil Blend

49.4 mg per serving

Other (inactive) ingredients: Maltodextrin, Gelatin, Magnesium Stearate, Ascorbic Acid. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lacidofil by XYMOGEN Drug Interactions

Want to check YOUR meds against Lacidofil?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Lactobacillus helveticus Rosell-52 182

Individual Drug Interactions

The ingredients in Lacidofil interact with 182 drugs. Click any drug to see the details.

1 of the 2 ingredients in Lacidofil interact with drugs. Each result below shows which ingredient is responsible. Lactobacillus helveticus Rosell-52

Each ingredient & the kinds of drugs it affects

For each ingredient in Lacidofil with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Lactobacillus helveticus Rosell-521 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus helveticus with antibiotic drugs might decrease the effectiveness of L. helveticus.
Lactobacillus helveticus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. helveticus preparations by at least two hours.

Likelihood Probable Evidence D
Lactobacillus helveticus Rosell-52 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Lacidofil, from the product label.

XYMOGEN

See all XYMOGEN products
Name
XYMOGEN Exclusive Professional Formulas
Street Address
6900 Kingspointe Pkwy.
City
Orlando
State
FL
ZipCode
32819
Phone Number
800-647-6100
Web Address
www.xymogen.com
Pharmacist Counseling Corner

Lacidofil by XYMOGEN: Common Questions

Does Lacidofil by XYMOGEN interact with any medications?
Yes. Based on its ingredients, Lacidofil has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Lacidofil contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Lacidofil while I'm on antibiotics?
You can, but timing helps. Antibiotics can kill the live bacteria in this supplement, so they may work against each other. Try to space them apart by a few hours — take your antibiotic at one time of day and Lacidofil at another. Your doctor or pharmacist can help you plan the best schedule.
Is Lacidofil safe if I have a weakened immune system?
Because Lacidofil contains live organisms and safety data are limited, people who are seriously ill or immunocompromised should be cautious. Check with your doctor before starting, since there's a small theoretical risk of infection in certain situations.
What does Lactobacillus helveticus actually do?
Lactobacillus helveticus is a probiotic strain — a type of beneficial bacteria. The exact benefits aren't yet well proven by rigorous trials, though it's being studied for gut health and other uses. We don't have reliable evidence yet for the conditions we track, so talk with your doctor about what it might do for you.
Does Lacidofil have a lot of fillers?
The inactive ingredients are maltodextrin, gelatin, magnesium stearate, and ascorbic acid — these help preserve and deliver the capsule. It's a short list, but that's fairly standard for a probiotic formula.
Can I take this while pregnant or breastfeeding?
We don't have pregnancy or breastfeeding safety data on file for this product. Talk with your doctor or midwife before starting if you're pregnant or nursing — they can advise you based on your individual situation.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lacidofil is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lacidofil label
Go deeper

The Full Monographs Behind Lacidofil’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lactobacillus Helveticus

Interacts with 182 drugs

Lactobacillus helveticus is a lactic acid bacterium used as a probiotic, often combined with other strains in mood, gut, and general wellness products. Early research is interesting—especial...

Read the full Lactobacillus Helveticus monograph →
Sources

Sources & How We Checked

Lacidofil's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactobacillus Helveticus 2 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed

See these in context on the Lactobacillus Helveticus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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