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Dietary supplement

Lycopene Ingredients & Drug Interactions

by NutriONN

Lycopene label
See full label image
Softgel Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Lycopene against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Lycopene is a dietary supplement by NutriONN with 1 active ingredient. Its ingredients are commonly taken for heart health, prostate health, antioxidant support.Based on those ingredients, 122 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lycopene. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Lycopene by NutriONN

Ask about any prescription or over-the-counter medication and we check it for interactions with Lycopene by NutriONN — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Lycopene by NutriONN

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This softgel contains one active ingredient: lycopene, a red pigment naturally found in tomatoes and other plants. It's the carotenoid (plant pigment) that gives tomatoes their color.

The softgel shell and fill include soybean oil, gelatin, corn oil, glycerin, beeswax, and purified water as inactive ingredients to hold and deliver the lycopene.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: support for blood pressure, eye, heart and prostate health.
  • We looked for evidence on: Hypertension, Age-related macular degeneration (AMD), Cataracts, Cardiovascular disease (CVD), Atherosclerosis, Hyperlipidemia — and 4 related terms.
  • The strongest evidence on file: Lycopene is rated "Possibly Effective" for Prostate cancer (Natural Medicines).
  • Also on file: Lycopene is rated "Insufficient Reliable Evidence To Rate" for Age-related macular degeneration (AMD), Atherosclerosis, Benign prostatic hyperplasia (BPH), Cardiovascular disease (CVD), and more.

The evidence for lycopene varies by use. For prostate cancer it's possibly effective — a fair amount of research suggests it may help, but the data isn't definitive.

For bladder cancer and diabetes, it's rated possibly ineffective based on the evidence we hold. For cholesterol management, exercise-induced asthma, and Lou Gehrig's disease, there isn't enough reliable evidence yet to say whether it works.

The evidence, ingredient by ingredient Lycopene

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lycopene from food is considered safe, and supplement doses are generally well tolerated. However, gastrointestinal side effects can occur — some people experience diarrhea, gas, bloating, nausea, vomiting, heartburn, or loss of appetite.

Pregnancy and breastfeeding safety data on supplements is limited; food amounts are fine, but there isn't enough information on supplement safety during pregnancy or nursing — talk with your doctor or pharmacist if you're pregnant, planning pregnancy, or breastfeeding.

Side effects, ingredient by ingredient Lycopene

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Lycopene.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 122 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start this supplement, double-check with your doctor or pharmacist if you take any blood thinners (anticoagulants) or antiplatelet drugs — these include warfarin, apixaban, dabigatran, rivaroxaban, aspirin, clopidogrel, and related medications. Lycopene may increase the risk of bleeding when combined with these drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

NutriONN Lycopene is worth considering if you're interested in prostate health support and aren't taking blood thinners or antiplatelet medications. If you take any clot-prevention drugs, check your specific medications with your doctor or pharmacist before starting.

Gastrointestinal upset is possible, and if you're pregnant or breastfeeding, discuss this supplement with your healthcare provider first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 23, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lycopene, straight from the product label.

Brand NutriONN
Barcode (UPC) X000Z27ONF
Net contents 120 Softgel(s)
Market status On market
Date entered into DSLD Apr 23, 2024
DSLD ID 308898
Product type Non-nutrient/non-botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lycopene by NutriONN, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
120
UPC/BARCODE
X000Z27ONF
IngredientAmount% DV
Lycopene10 mg--

Other ingredients: Soybean Oil, Gelatin, Corn Oil, Glycerin, yellow Beeswax, Gelatin, Vegetable Glycerin, Water, Purified

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Lycopene is a carotenoid which is a pigment that gives fruits and vegetables like tomatoes their bright red color. Lycopene is a powerful antioxidant, because the shape of the lycopene structure enables it to destroy free radicals that damage cells.

100% Natural tomato Powerful antioxidant Lycopene 10 mg per softgel

Formulation

Lycopene may show support for blood pressure, eye, hearth and prostate health.

Zero fillers Zero artificial ingredients

Heart health Eyesight support Hair health

Supports prostate health Immune system support Skin health support

No preservatives, no sugar, no starch, no milk, no lactose, no gluten, no wheat, no yeast, no fish, and no artificial color, flavor, or sweetener.

100% Natural

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take one (1) softgel daily preferably with meals.

Precautions

Caution: if you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur. Do not use if safety seal is damaged or missing.

Allergen: Contains soy and beeswax.

Keep out the reach of children.

Storage

Store at room temperature.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or mitigate any disease.

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Sourced From GMP Compliant Facility

Made in USA

General Statements

Please recycle

For special tips and discounts visit www.NutriONN.com

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Lycopene by NutriONN label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Lycopene label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Lycopene by NutriONN

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container120 Amounts shown are per serving.

Lycopene

Interacts with
122 drugs
10 mg per serving Form: Tomato

Lycopene is a red plant pigment and antioxidant found mainly in tomatoes and other red fruits. Eating lycopene-rich foods is linked with possible hear...

Lycopene monograph & interactions

Other (inactive) ingredients: Soybean Oil, Gelatin, Corn Oil, Glycerin, Yellow Beeswax, Gelatin, Vegetable Glycerin, Water, Purified. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lycopene by NutriONN Drug Interactions

Want to check YOUR meds against Lycopene?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
122Drugs
122 Moderate

Ingredients driving the most interactions

Lycopene 122

Individual Drug Interactions

The ingredients in Lycopene interact with 122 drugs. Click any drug to see the details.

1 of the 1 ingredient in Lycopene interact with drugs. Each result below shows which ingredient is responsible. Lycopene

Each ingredient & the kinds of drugs it affects

For each ingredient in Lycopene with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Lycopene1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
In vitro research shows that lycopene has antiplatelet effects.

Likelihood Possible Evidence D
Lycopene full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Lycopene, from the product label.

NutriONN

See all NutriONN products
Name
NutriONN
Street Address
6600 NE 78th Ct. B4, Suite 78399
City
Portland
State
OR
ZipCode
97218
Phone Number
(971) 213-8009
Web Address
www.nutrionn.com
Pharmacist Counseling Corner

Lycopene by NutriONN: Common Questions

Does Lycopene by NutriONN interact with any medications?
Yes. Based on its ingredients, Lycopene has a known interaction with 122 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Lycopene contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will lycopene help my prostate?
The evidence suggests it possibly could — there's enough research to say it may help prostate health, but it's not proven yet. Talk with your doctor about whether it's right for your situation.
What stomach side effects might I get?
Some people report diarrhea, gas, bloating, nausea, vomiting, heartburn, or loss of appetite when taking lycopene supplements. These aren't guaranteed to happen, but they're the most common reported issues.
Is it safe to take while I'm pregnant?
Lycopene from food is fine, but supplement safety in pregnancy isn't well studied. There's not enough data to say for sure either way. Talk with your doctor before taking this supplement if you're pregnant or planning pregnancy.
Can I take this while breastfeeding?
Food amounts of lycopene are safe, but there isn't enough research on supplement use while breastfeeding. Check with your doctor or pharmacist before starting.
Does this product have fillers?
Yes — the softgel includes soybean oil, corn oil, glycerin, gelatin, beeswax, and purified water as inactive ingredients to form and deliver the capsule.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lycopene is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lycopene label
Go deeper

The Full Monographs Behind Lycopene’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lycopene

Interacts with 122 drugs

Lycopene is a red plant pigment and antioxidant found mainly in tomatoes and other red fruits. Eating lycopene-rich foods is linked with possible heart and prostate benefits, but evidence fr...

Read the full Lycopene monograph →
Sources

Sources & How We Checked

Lycopene's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lycopene 10 references
  1. Sharma, J. B., Kumar, A., Kumar, A., Malhotra, M., Arora, R., Prasad, S., and Batra, S. Effect of lycopene on pre-eclampsia and intra-uterine growth retardation in primigravidas. Int J Gynaecol.Obstet. 2003;81(3):257-262. PubMed
  2. Hsiao, G., Wang, Y., Tzu, N. H., Fong, T. H., Shen, M. Y., Lin, K. H., Chou, D. S., and Sheu, J. R. Inhibitory effects of lycopene on in vitro platelet activation and in vivo prevention of thrombus formation. J Lab Clin Med 2005;146(4):216-226. PubMed
  3. Clark, P. E., Hall, M. C., Borden, L. S., Jr., Miller, A. A., Hu, J. J., Lee, W. R., Stindt, D., D'Agostino, R., Jr., Lovato, J., Harmon, M., and Torti, F. M. Phase I-II prospective dose-escalating trial of lycopene in patients with biochemical relapse o
  4. O'Kennedy, N., Crosbie, L., Whelan, S., Luther, V., Horgan, G., Broom, J. I., Webb, D. J., and Duttaroy, A. K. Effects of tomato extract on platelet function: a double-blinded crossover study in healthy humans. Am.J.Clin.Nutr. 2006;84(3):561-569. PubMed
  5. Jatoi, A., Burch, P., Hillman, D., Vanyo, J. M., Dakhil, S., Nikcevich, D., Rowland, K., Morton, R., Flynn, P. J., Young, C., and Tan, W. A tomato-based, lycopene-containing intervention for androgen-independent prostate cancer: results of a Phase II stu
  6. Schwenke, C., Ubrig, B., Thurmann, P., Eggersmann, C., and Roth, S. Lycopene for advanced hormone refractory prostate cancer: a prospective, open phase II pilot study. J.Urol. 2009;181(3):1098-1103. PubMed
  7. Banerjee, S., Jeyaseelan, S., and Guleria, R. Trial of lycopene to prevent pre-eclampsia in healthy primigravidas: results show some adverse effects. J.Obstet.Gynaecol.Res. 2009;35(3):477-482. PubMed
  8. Haseen, F., Cantwell, M. M., O'Sullivan, J. M., and Murray, L. J. Is there a benefit from lycopene supplementation in men with prostate cancer? A systematic review. Prostate Cancer Prostatic.Dis. 2009;12(4):325-332. PubMed
  9. Ilic, D., Forbes, K. M., and Hassed, C. Lycopene for the prevention of prostate cancer. Cochrane.Database.Syst.Rev. 2011;(11):CD008007. PubMed
  10. Sawardekar SB, Patel TC, Uchil D. Comparative evaluation of antiplatelet effect of lycopene with aspirin and the effect of their combination on platelet aggregation: an in vitro study. Indian J Pharmacol 2016;48:26-31. PubMed

See these in context on the Lycopene monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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