Major interaction on record — check this product against your medications before combining. Based on 2 of 6 ingredients. Check your meds →
Dietary supplement

M-P-S Muscle Builder Fruit Punch Ingredients & Drug Interactions

by Dymatize Nutrition

M-P-S Muscle Builder Fruit Punch label
See full label image
Powder Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking M-P-S Muscle Builder Fruit Punch against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

M-P-S Muscle Builder Fruit Punch is a dietary supplement by Dymatize Nutrition with 6 active ingredients. Its ingredients are commonly taken for bone health and osteoporosis prevention, dietary calcium deficiency, heartburn relief (calcium carbonate antacids).Based on those ingredients, 173 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Calcium, Whey Protein isolate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against M-P-S Muscle Builder Fruit Punch by Dymatize Nutrition

Ask about any prescription or over-the-counter medication and we check it for interactions with M-P-S Muscle Builder Fruit Punch by Dymatize Nutrition — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of M-P-S Muscle Builder Fruit Punch by Dymatize Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 4 of its 7 active ingredients.
  • “Chain-Sol 2:1:1 H2O-soluble BCAAs” is listed as a grouped ingredient — the label gives one combined amount (7 Gram(s)) without saying how much of each component you get.
  • “M-P-S MATRIX” is a proprietary blend — the label gives one combined amount (10.20 Gram(s)) without saying how much of each component you get.

M-P-S Muscle Builder contains 7 active ingredients. The main ones are calcium (a mineral essential for bone and muscle function), whey protein isolate (a complete protein from milk), and branched-chain amino acids (BCAAs)—leucine, isoleucine, and valine—which your muscles use during and after exercise.

The product also includes alpha-hydroxyisocaproic acid calcium and alpha-ketoisocaproic acid calcium, compounds related to amino acid metabolism. The powder also contains inactive ingredients like erythritol and sucralose for sweetness, citrus and fruit powders for flavor, and silica as a flow agent.

It's formulated as a fruit punch drink mix.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Anabolic support and muscle building.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Sarcopenia, HIV/AIDS-related wasting, Muscle recovery, Muscle protein synthesis — and 1 related terms.
  • The strongest evidence on file: Whey Protein is rated "Possibly Effective" for Athletic performance (Natural Medicines).
  • Also on file: Calcium is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced muscle damage.
  • Also on file: Whey Protein is rated "Insufficient Reliable Evidence To Rate" for HIV/AIDS-related wasting, Sarcopenia, Exercise-induced muscle damage.

Calcium in this product is effective for preventing and treating low calcium levels (hypocalcemia), for bone health in kidney failure, and for heartburn (dyspepsia), and is likely effective for osteoporosis. Whey protein isolate shows possibly effective evidence for athletic performance but insufficient reliable evidence for age-related cognitive decline or HIV/AIDS-related wasting; it's rated possibly ineffective for osteoporosis and COPD.

The effectiveness of the other active ingredients—the BCAAs and the alpha compounds—is not established in the data we hold.

The evidence, ingredient by ingredient Calcium Whey Protein

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Calcium is generally well tolerated at recommended doses. Common side effects are belching, constipation, diarrhea, flatulence, and stomach upset.

Very high doses raise theoretical concerns about kidney stones and a rare condition called calciphylaxis, and some research has suggested that calcium intake over 1500–2000 mg daily might be linked to increased prostate cancer risk, though results remain debated. Whey protein isolate is generally well tolerated by most healthy adults but is not well studied as a high-dose supplement.

Common side effects include bloating, cramps, diarrhea, headache, nausea, and reflux—most dose-related. Case reports have linked whey protein to acne onset or worsening, typically reversing when the product is stopped.

During pregnancy, adequate calcium is important; stay within recommended amounts unless your doctor advises otherwise. During breastfeeding, your calcium needs can be met through recommended amounts.

Safety data for whey protein in pregnancy and lactation is not on file for this product—talk with your doctor or pharmacist.

Side effects, ingredient by ingredient Calcium Whey Protein

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Calcium, Whey Protein.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: heart-rhythm medications; lithium; Parkinson's medications.
  • For scale: 173 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check before taking this product if you use dolutegravir, elvitegravir, or intravenous ceftriaxone (Major interactions with calcium). Also double-check if you take levodopa (Parkinson's disease; Major with whey protein), raltegravir or other HIV drugs, levothyroxine or other thyroid medications, heart medications like sotalol or diltiazem, psoriasis treatments, quinolone or tetracycline antibiotics, or bisphosphonates.

Your pharmacist or doctor can advise on timing or alternatives.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glancePartially disclosed formula with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This is a muscle-building supplement with evidence supporting calcium for bone health and whey protein for athletic performance, but it carries serious interactions with HIV medications, antibiotics, and other drugs. If you take any prescription medications—especially for HIV, thyroid disease, heart rhythm, antibiotics, or osteoporosis—check your exact medications with the tool on this page or talk to your pharmacist or doctor before starting.

Otherwise, most healthy people tolerate it well at the recommended dose.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 7 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about M-P-S Muscle Builder Fruit Punch, straight from the product label.

Brand Dymatize Nutrition
Barcode (UPC) 705016190003
Net contents 12.3 oz.; 350 Gram(s)
Market status On market
Date entered into DSLD Feb 25, 2015
DSLD ID 42390
Product type Other Combinations
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for M-P-S Muscle Builder Fruit Punch by Dymatize Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
17 Gram(s)
Maximum serving Sizes:
17 Gram(s)
Servings per container
20
UPC/BARCODE
705016190003
IngredientAmount% DV
Calories15 {Calories}--
Total Carbohydrates3 Gram(s)1%
Calcium110 mg11%
L-Leucine0 NP--
L-Isoleucine0 NP--
Protein2 Gram(s)4%
L-Valine0 NP--
Chain-Sol 2:1:1 H2O-soluble BCAAs7 Gram(s)--
M-P-S MATRIX10.2 Gram(s)--
Whey Protein isolate2.4 Gram(s)--
Alpha-Hydroxyisocaproic Acid Calcium500 mg--
Alpha-Ketoisocaproic Acid Calcium250 mg--

Other ingredients: Erythritol, Citric Acid, Beet, Natural and Artificial flavors, Tartaric Acid, Apple {powder}, Hibiscus powder, Malic Acid, Phosphoric Acid, Silicon Dioxide, Acesulfame Potassium, Sucralose, Soy Lecithin, Stevia leaf extract

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

NEW

PerformanceDriven

Anabolic Support

NATURALLY & ARTIFICIALLY FLAVORED

We know that you are performance driven, whether that be to improve lean body mass or compete at a higher level. Dymatize developed the new PerformanceDriven line with your goals in mind via Pre, Intra and Post training support. Dymatize M-P-S is designed to accelerate your fitness gains by both triggering muscle protein synthesis (anabolism) and minimizing muscle protein breakdown in response to training (catabolism) for faster recovery.

Great tasting and refreshing, M-P-S is the perfect muscle builder to take after your workouts.

DYMATIZE ENTERPRISES, LLC EEC APPROVED - PLANT# 3005816913

POST PRE INTRA

Formula

7g of Instantly Soluble BCAAs 2.4g of Whey Protein Isolate HICA & KIC

Contains Milk and Soy.

~ 7 grams of instantly soluble BCAAs (2:1:1) which provides enough L-Leucine to trigger muscle protein synthesis for faster muscle rebuild, recovery and growth ~ Added HICA & KIC (Leucine metabolites) further muscle protein synthesis and help limit muscle protein breakdown caused by strenuous training ~ 2.4g of whey protein isolate supports muscle protein synthesis

FDA Statement of Identity

DIETARY SUPPLEMENT

Precautions

Contains Milk and Soy.

Warning: Consult a physician before using this or any other product, if you are pregnant, lactating, or have any medical condition.

KEEP OUT OF REACH OF CHILDREN.

Suggested/Recommended/Usage/Directions

DIRECTIONS: As a dietary supplement, take 1 scoop (provided) as needed. Use 10oz. of water per scoop to taste. Mix/Shake until dissolved. Foaming may occur initially with agitation, but will subside.

One scoop post-workout is all you need.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Seals/Symbols

INFORMED-CHOICE.org Trusted by sport

General

8829

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

M-P-S Muscle Builder Fruit Punch by Dymatize Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

M-P-S Muscle Builder Fruit Punch label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in M-P-S Muscle Builder Fruit Punch by Dymatize Nutrition

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size17 Gram(s) Dosage formPowder Servings per container20 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Calcium

Interacts with
168 drugs
110 mg per serving

Calcium is an essential mineral your body needs for strong bones, nerve signaling, and muscle function, and supplements can help fill gaps when diet f...

Calcium monograph & interactions

Protein

2 Gram(s) per serving

M-P-S MATRIX

10.2 Gram(s) per serving
  • › Chain-Sol 2:1:1 H2O-soluble BCAAs

Whey Protein isolate

Interacts with
53 drugs
2.4 Gram(s) per serving

Whey protein is a high-quality, complete protein made from cow's milk that can help people meet protein needs and support muscle growth when combined...

Whey Protein isolate monograph & interactions

Alpha-Hydroxyisocaproic Acid Calcium

500 mg per serving

Alpha-Ketoisocaproic Acid Calcium

250 mg per serving

Other (inactive) ingredients: Erythritol, Citric Acid, Beet, Natural and Artificial flavors, Tartaric Acid, Apple {powder}, Hibiscus powder, Malic Acid, Phosphoric Acid, Silicon Dioxide, Acesulfame Potassium, Sucralose, Soy Lecithin, Stevia leaf extract. These complete the product’s ingredient list but are not active constituents.

Interaction report

M-P-S Muscle Builder Fruit Punch by Dymatize Nutrition Drug Interactions

Want to check YOUR meds against M-P-S Muscle Builder Fruit Punch?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
173Drugs
12 Major 143 Moderate 18 Minor

Ingredients driving the most interactions

Calcium 168
Whey Protein isolate 53

Individual Drug Interactions

The ingredients in M-P-S Muscle Builder Fruit Punch interact with 173 drugs. Click any drug to see the details.

2 of the 6 ingredients in M-P-S Muscle Builder Fruit Punch interact with drugs. Each result below shows which ingredient is responsible. Calcium Whey Protein isolate

Each ingredient & the kinds of drugs it affects

For each ingredient in M-P-S Muscle Builder Fruit Punch with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Calcium18 drug types · 168 drugs

Ceftriaxone (Rocephin)

Co-administration of intravenous calcium and ceftriaxone can result in precipitation of a ceftriaxone-calcium salt in the lungs and kidneys.
Avoid administering intravenous calcium in any form, such as parenteral nutrition or Lactated Ringers, within 48 hours of intravenous ceftriaxone. Case reports in neonates show that administering intravenous ceftriaxone and calcium can result in precipitation of a ceftriaxone-calcium salt in the lungs and kidneys. In several cases, neonates have died as a result of this interaction. So far there are no reports in adults; however, there is still concern that this interaction might occur in adults.

Likelihood Probable Evidence D
Dolutegravir (Tivicay)

Calcium seems to reduce levels of dolutegravir.
Advise patients to take dolutegravir either 2 hours before or 6 hours after taking calcium supplements. Pharmacokinetic research suggests that taking calcium carbonate 1200 mg concomitantly with dolutegravir 50 mg reduces plasma levels of dolutegravir by almost 40%. Calcium appears to decrease levels of dolutegravir through chelation.

Likelihood Probable Evidence B
Elvitegravir (Vitekta)

Calcium seems to reduce levels of elvitegravir.
Advise patients to take elvitegravir either 2 hours before or 2 hours after taking calcium supplements. Pharmacokinetic research suggests that taking calcium along with elvitegravir can reduce blood levels of elvitegravir through chelation.

Likelihood Probable Evidence B
Aluminum

Calcium citrate might increase aluminum absorption and toxicity. Other types of calcium do not increase aluminum absorption.
Calcium citrate can increase the absorption of aluminum when taken with aluminum hydroxide. The increase in aluminum levels may become toxic, particularly in individuals with kidney disease. However, the effect of calcium citrate on aluminum absorption is due to the citrate anion rather than calcium cation. Calcium acetate does not appear to increase aluminum absorption.

Likelihood Possible Evidence B
Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy)

Calcium might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption when taken in a fasting state.
Advise patients that bictegravir/emtricitabine/tenofovir alafenamide and calcium can be taken together if taken with food. However, if taken on an empty stomach, bictegravir/emtricitabine/tenofovir alafenamide should not be taken with, or 2 hours after, calcium containing products.

Likelihood Probable Evidence D
Bisphosphonates

Calcium reduces the absorption of bisphosphonates.
Advise patients to take bisphosphonates at least 30 minutes before calcium, but preferably at a different time of day. Calcium supplements decrease absorption of bisphosphonates.

Likelihood Probable Evidence C
Calcipotriene (Dovonex)

Taking calcipotriene with calcium might increase the risk for hypercalcemia.
Calcipotriene is a vitamin D analog used topically for psoriasis. It can be absorbed in sufficient amounts to cause systemic effects, including hypercalcemia. Theoretically, combining calcipotriene with calcium supplements might increase the risk of hypercalcemia.

Likelihood Possible Evidence B
Digoxin (Lanoxin)

Using intravenous calcium with digoxin might increase the risk of fatal cardiac arrhythmias.
Hypercalcemia increases the risk of fatal cardiac arrhythmias with digoxin. However, one retrospective analysis of clinical data suggests that intravenous calcium does not increase the risk of dysrhythmias or mortality in patients receiving digoxin.

Likelihood Possible Evidence B
Diltiazem (Cardizem, Others)

Theoretically, calcium may reduce the therapeutic effects of diltiazem.
Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically, calcium might increase this risk of hypercalcemia and reduce the effectiveness of diltiazem.

Likelihood Probable Evidence D
Levothyroxine (Synthroid, Others)

Calcium seems to reduce the absorption and effectiveness of levothyroxine.
Advise patients to take levothyroxine and calcium supplements at least 4 hours apart. Calcium reduces levothyroxine absorption, probably by forming insoluble complexes. Calcium carbonate supplements reduce effectiveness of levothyroxine in patients with hypothyroidism.

Likelihood Probable Evidence B
Lithium

Theoretically, concomitant use of calcium and lithium may increase this risk of hypercalcemia.
Clinical research suggests that long-term use of lithium may cause hypercalcemia in 10% to 60% of patients. Theoretically, concomitant use of lithium and calcium supplements may further increase this risk.

Likelihood Possible Evidence B
Quinolone Antibiotics

Calcium seems to reduce the absorption of quinolone antibiotics.
Advise patients to take oral quinolones at least 2 hours before or 4-6 hours after calcium supplements or calcium-fortified foods. Taking calcium at the same time as oral quinolones can reduce quinolone absorption. Calcium binds to quinolones in the gut.

Likelihood Probable Evidence B
Raltegravir (Isentress)

Calcium may reduce levels of raltegravir.
Pharmacokinetic research shows that taking a single dose of calcium carbonate 3000 mg along with raltegravir 400 mg twice daily modestly decreases the mean area under the curve of raltegravir, but the decrease does not necessitate a dose adjustment of raltegravir. However, a case of elevated HIV-1 RNA levels and documented resistance to raltegravir has been reported for a patient taking calcium carbonate 1 gram three times daily plus vitamin D3 (cholecalciferol) 400 IU three times daily in combination with raltegravir 400 mg twice daily for 11 months. It is thought that calcium reduced raltegravir levels by chelation, leading to treatment failure.

Likelihood Possible Evidence B
Sotalol (Betapace)

Calcium seems to reduce the absorption of sotalol.
Advise patients to separate doses by at least 2 hours before or 4-6 hours after calcium. Calcium appears to reduce the absorption of sotalol, probably by forming insoluble complexes.

Likelihood Possible Evidence B
Tetracycline Antibiotics

Calcium seems to reduce the absorption of tetracycline antibiotics.
Advise patients to take oral tetracyclines at least 2 hours before, or 4-6 hours after calcium supplements. Taking calcium at the same time as oral tetracyclines can reduce tetracycline absorption. Calcium binds to tetracyclines in the gut.

Likelihood Probable Evidence C
Thiazide Diuretics

Taking calcium along with thiazides might increase the risk of hypercalcemia and renal failure.
Thiazides reduce calcium excretion by the kidneys. Using thiazides along with moderately large amounts of calcium carbonate increases the risk of milk-alkali syndrome (hypercalcemia, metabolic alkalosis, renal failure). Patients may need to have their serum calcium levels and/or parathyroid function monitored regularly.

Likelihood Probable Evidence C
Verapamil (Calan, Others)

Theoretically, calcium may reduce the therapeutic effects of verapamil.
Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically, use of calcium supplements may increase this risk of hypercalcemia and reduce the effectiveness of verapamil.

Likelihood Probable Evidence D
Calcium Channel Blockers

Intravenous calcium may decrease the effects of calcium channel blockers; oral calcium is unlikely to have this effect.
Intravenous calcium is used to decrease the effects of calcium channel blockers in the management of overdose. Intravenous calcium gluconate has been used before intravenous verapamil (Isoptin) to prevent or reduce the hypotensive effects without affecting the antiarrhythmic effects. But there is no evidence that dietary or supplemental calcium when taken orally interacts with calcium channel blockers.

Likelihood Unlikely Evidence D
Calcium full monograph & interactions

Whey Protein isolate4 drug types · 53 drugs

Levodopa

Theoretically, whey protein might decrease levodopa absorption.
Small clinical studies show that concomitant ingestion of protein or high doses of leucine or isoleucine (100 mg/kg) and levodopa can exacerbate tremor, rigidity, and the "on-off" syndrome in patients with Parkinson disease.

Likelihood Probable Evidence D
Bisphosphonates

Theoretically, whey protein might reduce the absorption of bisphosphonates.
Whey protein contains minerals such as calcium that bind bisphosphonates in the gut. Advise patients to take bisphosphonates at least 30 minutes before whey protein, but preferably at a different time of day.

Likelihood Probable Evidence D
Quinolone Antibiotics

Theoretically, whey protein might decrease quinolone absorption.
Whey protein contains minerals, such as calcium, that can bind to quinolones in the gut. To avoid this interaction, advise patients to take oral quinolones at least 2 hours before or 4-6 hours after whey protein.

Likelihood Probable Evidence D
Tetracycline Antibiotics

Theoretically, whey protein might decrease tetracycline absorption.
Whey protein contains minerals, such as calcium, that bind to tetracyclines in the gut. To avoid this interaction, advise patients to take oral tetracyclines at least 2 hours before or 4-6 hours after whey protein.

Likelihood Probable Evidence D
Whey Protein isolate full monograph & interactions
The maker

Brand information

Manufacturer and brand details for M-P-S Muscle Builder Fruit Punch, from the product label.

Dymatize Nutrition

See all Dymatize Nutrition products
Name
Dymatize Enterprises, LLC
City
Dallas
State
TX
ZipCode
75234
Phone Number
888-334-5326
Web Address
DYMATIZE.COM
Pharmacist Counseling Corner

M-P-S Muscle Builder Fruit Punch by Dymatize Nutrition: Common Questions

Does M-P-S Muscle Builder Fruit Punch by Dymatize Nutrition interact with any medications?
Yes. Based on its ingredients, M-P-S Muscle Builder Fruit Punch has a known interaction with 173 medications, including 12 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
M-P-S Muscle Builder Fruit Punch contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this interfere with my thyroid medication?
Yes—calcium in this product can bind to levothyroxine and reduce how much your body absorbs. If you take levothyroxine (Synthroid or others), take it at least 4 hours away from this supplement. Check with your pharmacist or doctor about the best timing for your routine.
Can I take this if I'm on an antibiotic?
It depends on which antibiotic. If you're taking a quinolone (like ciprofloxacin) or tetracycline (like doxycycline), the whey protein can interfere with absorption. Space them at least 2 hours before or 4–6 hours after the supplement. Ask your pharmacist to confirm your specific antibiotic.
What's in the BCAAs—do they interact with anything?
The product contains leucine, isoleucine, and valine (branched-chain amino acids). We don't have interaction data on file for these individually, but whey protein (which contains them in high amounts) has a documented interaction with levodopa for Parkinson's disease. If you take levodopa, mention this product to your doctor or pharmacist.
Is it safe to take while pregnant or breastfeeding?
Calcium is important during pregnancy and lactation, and the amounts here are generally fine—just stay within recommended daily totals unless your doctor says otherwise. We don't have complete safety data on file for the whey protein isolate during pregnancy or breastfeeding, so talk with your doctor or pharmacist for personalized advice.
What are the most common side effects?
From calcium, you might notice belching, constipation, diarrhea, or stomach upset. From whey protein, common effects are bloating, cramps, diarrhea, headache, nausea, and reflux—most of these are dose-related and often improve if you lower the amount.
Could this cause acne?
Whey protein has been reported to trigger acne onset or worsen existing acne in teenagers and young adults, especially at high doses. If you notice acne develop or worsen, stop using the product and discuss it with your doctor or dermatologist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

M-P-S Muscle Builder Fruit Punch label
Go deeper

The Full Monographs Behind M-P-S Muscle Builder Fruit Punch’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Calcium

Interacts with 168 drugs

Calcium is an essential mineral your body needs for strong bones, nerve signaling, and muscle function, and supplements can help fill gaps when diet falls short. Most people do best getting...

Read the full Calcium monograph → Herb & supplement monograph

Whey Protein

Interacts with 53 drugs

Whey protein is a high-quality, complete protein made from cow's milk that can help people meet protein needs and support muscle growth when combined with exercise. It is generally safe for...

Read the full Whey Protein monograph →
Sources

Sources & How We Checked

M-P-S Muscle Builder Fruit Punch's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 87 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Calcium 62 references
  1. Shils M, Olson A, Shike M. Modern Nutrition in Health and Disease. 8th ed. Philadelphia, PA: Lea and Febiger, 1994.
  2. Hernandez-Avila M, Gonzalez-Cossio T, Hernandez-Avila JE, et al. Dietary calcium supplements to lower blood lead levels in lactating women: a randomized placebo-controlled trial. Epidemiology 2003;14:206-12.. PubMed
  3. Thys-Jacobs S, Ceccarelli S, Bierman A, et al. Calcium supplementation in premenstrual syndrome: a randomized crossover trial. J Gen Intern Med 1989;4:183-9. PubMed
  4. Maton PN, Burton ME. Antacids revisited: a review of their clinical pharmacology and recommended therapeutic use. Drugs 1999;57:855-70.
  5. Clemens JD, Feinstein AR. Calcium carbonate and constipation: a historical review of medical mythopoeia. Gastroenterology 1977;72:957-61. DOI
  6. Saunders D, Sillery J, Chapman R. Effect of calcium carbonate and aluminum hydroxide on human intestinal function. Dig Dis Sci 1988;33:409-13. PubMed
  7. Friedman PA, Bushinsky DA. Diuretic effects on calcium metabolism. Semin Nephrol 1999;19:551-6.
  8. Koo WK, Walters JC, Esterlitz J, et al. Maternal calcium supplementation and fetal bone mineralization. Obstet Gynecol 1999;94:577-82. DOI
  9. Raman L, Rajalakshmi K, Krishnamachari KAVR, et al. Effect of calcium supplementation to undernourished mothers during pregnancy on the bone density of the neonates. Am J Clin Nutr 1978; 31:466-9. DOI
  10. Murry JJ, Healy MD. Drug-mineral interactions: a new responsibility for the hospital dietician. J Am Diet Assoc 1991;91:66-73.
  11. Chan JM, Giovannucci E, Andersson SO, et al. Dairy products, calcium, phosphorous, vitamin D, and risk of prostate cancer. Cancer Causes Control 1998;9:559-66.
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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