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Dietary supplement

Mega-Liposomal R-ALA Organic Fruit Flavor Ingredients & Drug Interactions

by Aurora NutraScience

Mega-Liposomal R-ALA Organic Fruit Flavor label
See full label image
Liquid Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Mega-Liposomal R-ALA Organic Fruit Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Mega-Liposomal R-ALA Organic Fruit Flavor is a dietary supplement by Aurora NutraScience with 4 active ingredients. Its ingredients are commonly taken for replacing fluids and electrolytes, preventing dehydration during exercise or illness, treating low blood sodium (under medical care).Based on those ingredients, 463 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are R-Alpha Lipoic Acid, Sodium, Coenzyme Q10. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Mega-Liposomal R-ALA Organic Fruit Flavor by Aurora NutraScience

Ask about any prescription or over-the-counter medication and we check it for interactions with Mega-Liposomal R-ALA Organic Fruit Flavor by Aurora NutraScience — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Mega-Liposomal R-ALA Organic Fruit Flavor by Aurora NutraScience

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 4 of its 4 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This liquid supplement contains 4 active ingredients. Sodium is included at a level that may interact with several medication classes; coenzyme Q10 supports cellular energy and has antioxidant properties; L-carnitine aids in fat metabolism and energy production; and R-alpha lipoic acid is an antioxidant compound.

The product also contains inactive ingredients — purified water, glycerin, soy lecithin, natural flavors, potassium sorbate, stevia leaf extract, and xanthan gum — which serve as the base, sweetener, and thickening agents.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Cellular support complex.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

Evidence for these ingredients varies. Coenzyme Q10 is likely effective for coenzyme Q10 deficiency and possibly effective for fibromyalgia, migraine, congestive heart failure, and diabetic neuropathy.

L-carnitine is effective for L-carnitine deficiency and possibly effective for high cholesterol, heart failure, and angina. R-alpha lipoic acid is possibly effective for diabetic nerve damage, high cholesterol, and weight management.

Sodium's clinical uses in this formulation — cystic fibrosis (likely effective) and amphotericin B kidney toxicity (possibly effective) — are specific medical contexts; broader effectiveness evidence for this product as a whole is not established in our data.

The evidence, ingredient by ingredient Sodium Coenzyme Q10 L-carnitine Alpha-lipoic Acid

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Coenzyme Q10 is generally well tolerated; gastrointestinal side effects like nausea and diarrhea occur in less than 1% of people. L-carnitine is also generally well tolerated at typical doses, though high doses may cause stomach upset and a fish-like body odor.

R-alpha lipoic acid is generally well tolerated orally; common side effects are headache, heartburn, nausea, and vomiting. Sodium, however, requires caution — while normal dietary amounts are fine, too much is linked to high blood pressure and heart strain.

You should avoid sodium supplements or very high intake without medical advice. For pregnancy and breastfeeding, the safety picture is mixed: sodium is likely safe in pregnancy but possibly unsafe during lactation; coenzyme Q10 has insufficient data; L-carnitine is possibly safe during lactation but pregnancy data are not on file; R-alpha lipoic acid should be avoided in pregnancy and lactation due to insufficient safety information.

Side effects, ingredient by ingredient Sodium Coenzyme Q10 L-carnitine Alpha-lipoic Acid

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 4 of the 4 matched ingredients can interact with medications — Alpha-lipoic Acid, Coenzyme Q10, L-carnitine, Sodium.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; cancer treatments; diabetes medications; lithium.
  • For scale: 463 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before taking this product if you use blood thinners (warfarin, acenocoumarol, or other anticoagulant or antiplatelet drugs), blood pressure medications, chemotherapy drugs, thyroid hormone replacement, lithium, corticosteroids, diabetes medications, or didanosine. Sodium in this formula can also interact with sodium phosphate solutions and tolvaptan.

Altogether, these interactions span 463 individual medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This four-ingredient formula carries Moderate-severity interactions with blood thinners, blood pressure medications, thyroid drugs, and several chemotherapy agents, plus concerns with lithium, corticosteroids, and diabetes medications. Before starting, talk with your doctor or pharmacist about whether this product fits your current medications and health conditions — especially if you take any blood pressure or heart medications, blood thinners, thyroid hormone, chemotherapy, or lithium.

If you have questions about a specific medication, use the checker below.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Mega-Liposomal R-ALA Organic Fruit Flavor, straight from the product label.

Brand Aurora NutraScience
Barcode (UPC) 628504648032
Net contents 16 Fluid Ounce(s); 480 Milliliter(s)
Market status On market
Date entered into DSLD Nov 22, 2022
DSLD ID 276651
Product type Non-nutrient/non-botanical
Supplement form Liquid
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Mega-Liposomal R-ALA Organic Fruit Flavor by Aurora NutraScience, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
15 mL
Maximum serving Sizes:
15 mL
Servings per container
32
UPC/BARCODE
628504648032
IngredientAmount% DV
Calories30 Calorie(s)--
Total Carbohydrates6 Gram(s)2%
Sodium20 mg1%
Total Fat0.5 Gram(s)1%
Coenzyme Q10100 mg--
L-Carnitine1000 mg--
R-Alpha Lipoic Acid200 mg--

Other ingredients: purified Water, Glycerin, Soy Lecithin, Natural Flavors, Potassium Sorbate, Stevia leaf extract, Xanthan Gum

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Mega-Liposomal R-ALA

Why use Mega-Liposomal R-ALA? Our Mega-Liposomal R-ALA nutrients are encapsulated into all-natural lipospheres. This helps to protect the nutrients while facilitating a more efficient transition through the digestive system and into the body's bloodstream. We use only 100% organic fruit flavoring and natural stevia leaf extract to give our product a great taste that everyone can enjoy!

Formulation

Cellular support complex Liposomal delivery technology

Gluten free Non GMO ingredients Sugar free

We use only 100% organic fruit flavoring and natural stevia leaf extract to give our product a great taste that everyone can enjoy!

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Shake gently

Suggested use As a dietary supplement, take 1 tablespoon (15mL) daily or as directed by your healthcare professional. Shake gently before each use. Take anytime, preferably on an empty stomach. Drink straight or with cold water, juice or yogurt. Do not high speed machine blend.

Best if consumed within 45 days of opening.

Storage

Refrigerate after opening

Store in cool dry place away from heat or direct sunlight. Refrigerate after opening.

Precautions

Keep out of reach of children.

Consult your healthcare provider if you are pregnant or breastfeeding before consuming this product.

Tamper evident customer protection: Do not use if product label has been removed or if tamper-evident cap security ring is not intact.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

Recycle

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Mega-Liposomal R-ALA Organic Fruit Flavor by Aurora NutraScience label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Mega-Liposomal R-ALA Organic Fruit Flavor label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Mega-Liposomal R-ALA Organic Fruit Flavor by Aurora NutraScience

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size15 mL Dosage formLiquid Servings per container32 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sodium

Interacts with
205 drugs
20 mg per serving

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...

Sodium monograph & interactions

Coenzyme Q10

Interacts with
198 drugs
100 mg per serving

CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated...

Coenzyme Q10 monograph & interactions

L-Carnitine

Interacts with
19 drugs
1000 mg per serving

L-carnitine is a compound your body makes naturally and also gets from foods like meat. It helps cells turn fat into energy, and supplements are most...

L-Carnitine monograph & interactions

R-Alpha Lipoic Acid

Interacts with
263 drugs
200 mg per serving

Alpha-lipoic acid (ALA) is an antioxidant made naturally by the body and found in small amounts in foods. It is most studied for diabetic nerve pain,...

R-Alpha Lipoic Acid monograph & interactions

Other (inactive) ingredients: Purified Water, Glycerin, Soy Lecithin, Natural Flavors, Potassium Sorbate, Stevia leaf extract, Xanthan Gum. These complete the product’s ingredient list but are not active constituents.

Interaction report

Mega-Liposomal R-ALA Organic Fruit Flavor by Aurora NutraScience Drug Interactions

Want to check YOUR meds against Mega-Liposomal R-ALA Organic Fruit Flavor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
463Drugs
377 Moderate 86 Minor

Ingredients driving the most interactions

R-Alpha Lipoic Acid 263
Sodium 205
Coenzyme Q10 198
L-Carnitine 19

Individual Drug Interactions

The ingredients in Mega-Liposomal R-ALA Organic Fruit Flavor interact with 463 drugs. Click any drug to see the details.

4 of the 4 ingredients in Mega-Liposomal R-ALA Organic Fruit Flavor interact with drugs. Each result below shows which ingredient is responsible. R-Alpha Lipoic Acid Sodium Coenzyme Q10 L-Carnitine

Each ingredient & the kinds of drugs it affects

For each ingredient in Mega-Liposomal R-ALA Organic Fruit Flavor with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

R-Alpha Lipoic Acid5 drug types · 263 drugs

Alkylating Agents

Theoretically, the antioxidant effects of alpha-lipoic acid might alter the effectiveness of alkylating agents.
The use of antioxidants like alpha-lipoic acid during chemotherapy is controversial. There are concerns that antioxidants could reduce the activity of chemotherapy drugs that generate free radicals. However, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that might interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effect, if any, antioxidants such as alpha-lipoic acid have on chemotherapy. Advise patients to consult their oncologist before using alpha-lipoic acid.

Likelihood Possible Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro, alpha-lipoic acid inhibits platelet aggregation.

Likelihood Possible Evidence D
Antitumor Antibiotics

Theoretically, the antioxidant effects of alpha-lipoic acid might alter the effectiveness of antitumor antibiotics.
The use of antioxidants like alpha-lipoic acid during chemotherapy is controversial. There are concerns that antioxidants could reduce the activity of antitumor antibiotic drugs, which work by generating free radicals. However, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that might interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effect, if any, antioxidants such as alpha-lipoic acid have on chemotherapy involving antitumor antibiotics. Advise patients to consult their oncologist before using alpha-lipoic acid.

Likelihood Possible Evidence D
Thyroid Hormone

Theoretically, alpha-lipoic acid might decrease the effects of thyroid hormone drugs.
Animal research suggests that co-administration of thyroxine with alpha-lipoic acid reduces conversion into the active T3 form.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, taking alpha-lipoic acid with antidiabetes drugs might increase the risk of hypoglycemia.
Although some small clinical studies have suggested that alpha-lipoic acid can lower blood glucose levels, larger clinical studies in patients with diabetes have shown no clinically meaningful effect. Additionally, co-administration of single doses of alpha-lipoic acid and glyburide or acarbose did not cause detectable drug interactions in healthy volunteers.

Likelihood Unlikely Evidence B
R-Alpha Lipoic Acid full monograph & interactions

Sodium7 drug types · 205 drugs

Antihypertensive Drugs

Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.

Likelihood Probable Evidence A
Corticosteroids

Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.

Likelihood Possible Evidence D
Didanosine (Videx)

Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.

Likelihood Probable Evidence C
Lithium

Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.

Likelihood Probable Evidence B
Sodium Phosphates

Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Sodium-Containing Drugs

Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Tolvaptan (Samsca)

Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.

Likelihood Probable Evidence C
Sodium full monograph & interactions

Coenzyme Q103 drug types · 198 drugs

Alkylating Agents

Coenzyme Q10 has antioxidant effects. Theoretically, this may reduce the activity of chemotherapy drugs that generate free radicals.
Theoretically, antioxidants such as coenzyme Q10 might protect tumor cells from chemotherapeutic agents that work by inducing oxidative stress, such as alkylating agents (e.g., cyclophosphamide) and radiation therapy. The clinical importance of this interaction is unknown.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Concomitant use of coenzyme Q10 and warfarin might reduce the anticoagulant effects of warfarin. Four cases of decreased warfarin efficacy thought to be due to coenzyme Q10 have been reported. However, there is some preliminary clinical research that suggests coenzyme Q10 might not significantly decrease the effects of warfarin in patients who have a stable INR.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Some clinical research shows that coenzyme Q10 can significantly lower blood pressure, although other studies have shown conflicting results.

Likelihood Possible Evidence B
Coenzyme Q10 full monograph & interactions

L-Carnitine3 drug types · 19 drugs

Acenocoumarol (Sintrom)

Theoretically, L-carnitine might increase the anticoagulant effects of acenocoumarol.
L-carnitine might enhance the anticoagulant effects of acenocoumarol, an oral anticoagulant similar to warfarin, but shorter-acting. There are at least two case reports of INR elevation with concomitant use. In one case, a 33-year-old male with a previously stable INR had an elevated INR of 4.65 after L-carnitine was started and continued for 10 weeks. INR normalized after discontinuation of the L-carnitine-containing product.

Likelihood Possible Evidence D
Thyroid Hormone

Theoretically, L-carnitine might decrease the effectiveness of thyroid hormone replacement.
L-carnitine appears to act as a peripheral thyroid hormone antagonist by inhibiting entry of thyroid hormone into the nucleus of cells. Taking L-carnitine also seems to diminish some of the symptoms of hyperthyroidism.

Likelihood Probable Evidence B
Warfarin (Coumadin)

Theoretically, L-carnitine might increase the anticoagulant effects of warfarin.
L-carnitine might increase the anticoagulant effects of acenocoumarol, a shorter-acting oral anticoagulant similar to warfarin. There is not enough information to know whether this interaction occurs with L-carnitine and warfarin.

Likelihood Possible Evidence D
L-Carnitine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Mega-Liposomal R-ALA Organic Fruit Flavor, from the product label.

Aurora NutraScience

Name
Vida Lifescience
City
Irvine
State
CA
Phone Number
1-844-321-8432
Web Address
www.VidaLifescience.com
Pharmacist Counseling Corner

Mega-Liposomal R-ALA Organic Fruit Flavor by Aurora NutraScience: Common Questions

Does Mega-Liposomal R-ALA Organic Fruit Flavor by Aurora NutraScience interact with any medications?
Yes. Based on its ingredients, Mega-Liposomal R-ALA Organic Fruit Flavor has a known interaction with 463 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Mega-Liposomal R-ALA Organic Fruit Flavor contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while I'm on warfarin or another blood thinner?
This product contains coenzyme Q10, L-carnitine, and R-alpha lipoic acid — all of which have documented Moderate interactions with blood thinners. Additionally, the sodium content can affect how your blood thinner works. Talk with your doctor or pharmacist before combining them; you may need blood work monitoring or a dose adjustment.
Is this safe to take while pregnant or breastfeeding?
The safety data differ by ingredient. Sodium is likely safe in pregnancy but possibly unsafe during breastfeeding. R-alpha lipoic acid should be avoided in both pregnancy and lactation due to insufficient safety information. Coenzyme Q10 and L-carnitine have gaps in the data for these periods. Talk with your doctor before using during pregnancy or breastfeeding — they can weigh the risks and benefits for your situation.
What is R-alpha lipoic acid, and what does it do?
R-alpha lipoic acid is an antioxidant compound that may help reduce oxidative stress in the body. Our data show it is possibly effective for diabetic nerve damage, high cholesterol, and weight management, though the evidence is not definitive.
Can this supplement help my high cholesterol?
Coenzyme Q10 and L-carnitine are both possibly effective for high cholesterol, as is R-alpha lipoic acid. That said, possibly effective means the evidence is modest and not conclusive — talk with your doctor about whether this product is right for your situation and how it fits with any cholesterol medications you're taking.
Will this product lower my blood sugar?
R-alpha lipoic acid is listed as possibly effective for weight management, and there's a theoretical Minor concern that it could increase the risk of low blood sugar if taken with diabetes medications. If you use diabetes drugs, talk with your doctor before starting this supplement and monitor your blood sugar closely.
What are the most common side effects?
Coenzyme Q10 and L-carnitine most often cause digestive upset — nausea, diarrhea, or heartburn — though these occur in less than 1% of people. R-alpha lipoic acid may cause headache, heartburn, nausea, or vomiting. The sodium in this formula carries a bigger concern: excess intake is linked to high blood pressure and heart strain.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Mega-Liposomal R-ALA Organic Fruit Flavor label
Go deeper

The Full Monographs Behind Mega-Liposomal R-ALA Organic Fruit Flavor’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Sodium

Interacts with 205 drugs

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets get more than enough—often too much—from...

Read the full Sodium monograph → Herb & supplement monograph

Coenzyme Q10

Interacts with 198 drugs

CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated and is most studied for heart condition...

Read the full Coenzyme Q10 monograph → Herb & supplement monograph

L-carnitine

Interacts with 19 drugs

L-carnitine is a compound your body makes naturally and also gets from foods like meat. It helps cells turn fat into energy, and supplements are most clearly useful for people with a true ca...

Read the full L-carnitine monograph → Herb & supplement monograph

Alpha-lipoic Acid

Interacts with 263 drugs

Alpha-lipoic acid (ALA) is an antioxidant made naturally by the body and found in small amounts in foods. It is most studied for diabetic nerve pain, where some evidence suggests it may help...

Read the full Alpha-lipoic Acid monograph →
Sources

Sources & How We Checked

Mega-Liposomal R-ALA Organic Fruit Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 167 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sodium 38 references
  1. Garabedian-Ruffalo SM, Ruffalo RL. Drug and nutrient interactions. Am Fam Physician 1986;33:165-74.
  2. Food and Drug Administration Science Background: Safety of Sodium Phosphates Oral Solution. September 17, 2001. Available at: http://www.fda.gov/cder/drug/safety/sodiumphospate.htm
  3. Coton T, Mallaret C, Coilliot C, Carre D, Guisset M. Severe acute ulcerated gastritis induced by salt. Presse Med 2009;38(3):499-500. PubMed
  4. Frings-Meuthen P, Buehlmeier J, Baecker N, et al. High sodium chloride intake exacerbates immobilization-induced bone resorption and protein losses. J Appl Physiol 2011;111(2):537-542. PubMed
  5. Frings-Meuthen P, Baecker N, Heer M. Low-grade metabolic acidosis may be the cause of sodium chloride-induced exaggerated bone resorption. J Bone Miner Res 2008;23(4):517-524. PubMed
  6. Alam S, Johnson AG. A meta-analysis of randomised controlled trials (RCT) among healthy normotensive and essential hypertensive elderly patients to determine the effect of high salt (NaCl) diet of blood pressure. J Hum Hypertens 1999;13(6):367-74.
  7. Boudville N, Ward S, Benaroia M, House AA. Increased sodium intake correlates with greater use of antihypertensive agents by subjects with chronic kidney disease. Am J Hypertens 2005;18(10):1300-5. PubMed
  8. Bennett WM. Drug interactions and consequences of sodium restriction. Am J Clin Nutr 1997;65(2 Suppl):678S-681S. PubMed
  9. Okusa MD, Crystal LJ. Clinical manifestations and management of acute lithium intoxication. Am J Med 1994;97(4):383-9. PubMed
  10. Food and Nutrition Board, Institute of Medicine. Dietary reference intakes for water, potassium, sodium, chloride, and sulfate. Washington, DC: National Academy Press, 2005. Available at: http://www.nap.edu/openbook.php?record_id=10925. DOI
  11. D'Elia L, Rossi G, Ippolito R, Cappuccio FP, Strazzullo P. Habitual salt intake and risk of gastric cancer: a meta-analysis of prospective studies. Clin Nutr 2012;31(4):489-98. PubMed
  12. Goldsmith SR. Hyponatremia in heart failure: time for a trial. J Card Fail 2013;19(6):398-400. PubMed
  13. Willocks L, Brettle R, Keen J, Valentine C, Pinching AJ. Formulations of didanosine (ddI) and salt overload. Lancet 1992;339(8786):190.
  14. Chen L, Zhang Z, Chen W, Whelton PK, Appel LJ. Lower Sodium Intake and Risk of Headaches: Results From the Trial of Nonpharmacologic Interventions in the Elderly. Am J Public Health. 2016;106(7):1270-5. PubMed
  15. Cook NR, Appel LJ, Whelton PK. Lower levels of sodium intake and reduced cardiovascular risk. Circulation. 2014;129(9):981-9. PubMed
  16. Cook NR, Appel LJ, Whelton PK. Sodium Intake and All-Cause Mortality Over 20 Years in the Trials of Hypertension Prevention. J Am Coll Cardiol. 2016;68(15):1609-1617. PubMed
  17. Mente A, O'Donnell M, Rangarajan S, et al. Associations of urinary sodium excretion with cardiovascular events in individuals with and without hypertension: a pooled analysis of data from four studies. Lancet. 2016;388(10043):465-75. PubMed
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See these in context on the Alpha-lipoic Acid monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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