Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

MetaKids Probiotic Ingredients & Drug Interactions

by Metagenics

MetaKids Probiotic label
See full label image
Tablet Or Pill Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking MetaKids Probiotic against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

MetaKids Probiotic is a dietary supplement by Metagenics with 2 active ingredients. Its ingredients are commonly taken for digestive health and balance, diarrhea (including antibiotic-related), vaginal yeast and bacterial infections.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lactobacillus acidophilus NCFM. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against MetaKids Probiotic by Metagenics

Ask about any prescription or over-the-counter medication and we check it for interactions with MetaKids Probiotic by Metagenics — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of MetaKids Probiotic by Metagenics

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 2 active ingredients.
  • “A Probiotic Blend” is a proprietary blend — the label gives one combined amount (107.80 mg) without saying how much of each component you get.

MetaKids Probiotic contains 2 active ingredients: Lactobacillus acidophilus NCFM and Bifidobacterium lactis Bi-07, both live beneficial bacteria that support digestive and immune health in children. The product also includes a proprietary probiotic blend.

These are delivered in a tablet or pill form alongside inactive ingredients (excipients) like xylitol, natural flavors, and cellulose.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Lactobacillus Acidophilus's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: support immune health.
  • We looked for evidence on: Respiratory tract infections, immune function, infection prevention, immune response.
  • The closest evidence on file: Lactobacillus Acidophilus is rated "Insufficient Reliable Evidence To Rate" for Respiratory tract infections (Natural Medicines).

The Lactobacillus acidophilus in this product is rated Possibly Effective for irritable bowel syndrome (IBS), Helicobacter pylori infection, antibiotic-associated diarrhea, and bacterial vaginosis. It's rated Possibly Ineffective for atopic disease (allergic conditions), and the evidence is insufficient to rate its role in acute respiratory distress syndrome.

We hold no effectiveness data for Bifidobacterium lactis Bi-07.

The evidence, ingredient by ingredient Lactobacillus Acidophilus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactobacillus acidophilus is generally well tolerated in healthy children. In rare cases, oral use can cause mild gastrointestinal side effects like stomach discomfort, bloating, gas, diarrhea, or vomiting—though these are uncommon.

Because L. acidophilus preparations contain live microorganisms, there is a theoretical concern about pathogenic infection in certain patients, though this is rare and typically occurs in people with compromised immune systems or underlying conditions. Pregnancy is rated Possibly Safe for this ingredient.

Check with your child's doctor before starting, especially if your child has a weakened immune system.

Side effects, ingredient by ingredient Lactobacillus Acidophilus

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Lactobacillus Acidophilus.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before your child takes MetaKids Probiotic, check with your doctor or pharmacist if they're on antibiotic drugs—Moderate interaction risk. Separate the timing of the probiotic and antibiotics by several hours, as antibiotics can kill the live bacteria in the product.

For the Bifidobacterium lactis ingredient, we hold no interaction data, so run your child's complete medication list through the checker below to be sure.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

MetaKids Probiotic is a two-strain live probiotic meant to support digestive and immune health in children and shows Possibly Effective evidence for IBS and antibiotic-associated diarrhea. The main caution is timing with antibiotics—they can interfere with each other.

Talk with your child's doctor or pharmacist before starting, particularly if your child takes antibiotics, has a weakened immune system, or has any underlying health conditions.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 24, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about MetaKids Probiotic, straight from the product label.

Brand Metagenics
Barcode (UPC) 755571948694
Net contents 120 Tablet(s)
Market status On market
Date entered into DSLD Mar 24, 2020
DSLD ID 216413
Product type Other Combinations
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Vegetarian, Gluten Free, Children more than 1 but less than 4
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for MetaKids Probiotic by Metagenics, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
2 Tablet(s)
Servings per container
60
UPC/BARCODE
755571948694
IngredientAmount% DV
Calories5 Calorie(s)--
Total Carbohydrates1 Gram(s)1%, 1%
Sugar Alcohol1 Gram(s)--
Lactobacillus acidophilus NCFM----
Bifidobacterium lactis Bi-07----
A Probiotic Blend107.8 mg--

Other ingredients: Xylitol, Natural Flavors, Sorbitol, Microcrystalline Cellulose, Fruit and Vegetable juice colors, DL-Malic Acid, Citric Acid, Stearic Acid, Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

MetaKids Probiotic provides a proprietary blend of highly viable, pure strains of "friendly" bacteria that have been clinically shown to support immune health. This delicious, naturally grape flavored chewable formula is backed by the Metagenics ID Guarantee for purity, clinical reliability, and safety via scientific identification of strains with established health benefits.

Suggested/Recommended/Usage/Directions

Directions: Children age 3 and older chew one to two tablets once daily or as directed by your healthcare provider. Chew or crush tablets completely before swallowing. Do not swallow tablets whole.

Formulation

This product is non-GMO, gluten free, and vegetarian.

This product is non-GMO, gluten free, and vegetarian.

Chewable daily probiotic support

Precautions

Caution: Not recommended for children under 3 years of age due to risk of choking. Keep out of the reach of children.

Use under adult supervision. Tamper Evident: Do not use if safety seal is missing or broken.

Storage

Storage: Keep refrigerated.

Seals/Symbols

GF Certified Gluten-free

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Probiotic Supplement

General Statements

Practitioner Exclusive

Brand IP Statement(s)

NCFM and Bi-07 are registered trademarks licensed by DuPont

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

MetaKids Probiotic by Metagenics label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

MetaKids Probiotic label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in MetaKids Probiotic by Metagenics

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

A Probiotic Blend

107.8 mg per serving

Other (inactive) ingredients: Xylitol, Natural Flavors, Sorbitol, Microcrystalline Cellulose, Fruit and Vegetable juice colors, DL-Malic Acid, Citric Acid, Stearic Acid, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

MetaKids Probiotic by Metagenics Drug Interactions

Want to check YOUR meds against MetaKids Probiotic?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Lactobacillus acidophilus NCFM 182

Individual Drug Interactions

The ingredients in MetaKids Probiotic interact with 182 drugs. Click any drug to see the details.

1 of the 2 ingredients in MetaKids Probiotic interact with drugs. Each result below shows which ingredient is responsible. Lactobacillus acidophilus NCFM

Each ingredient & the kinds of drugs it affects

For each ingredient in MetaKids Probiotic with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Lactobacillus acidophilus NCFM1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D
Lactobacillus acidophilus NCFM full monograph & interactions
The maker

Brand information

Manufacturer and brand details for MetaKids Probiotic, from the product label.

Metagenics

See all Metagenics products
Name
Metagenics
City
Gig Harbor
State
WA
ZipCode
98332
Phone Number
800 692 9400
Web Address
metagenics.com
Pharmacist Counseling Corner

MetaKids Probiotic by Metagenics: Common Questions

Does MetaKids Probiotic by Metagenics interact with any medications?
Yes. Based on its ingredients, MetaKids Probiotic has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
MetaKids Probiotic contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I give this to my child while they're on antibiotics?
You can, but timing matters. Antibiotics can kill the live beneficial bacteria in the probiotic, making it less effective. Ask your doctor or pharmacist to help you space them out—often several hours apart works well. Don't stop the antibiotic; just coordinate the timing.
Is this safe for my young child?
Lactobacillus acidophilus is generally well tolerated in healthy children. However, if your child has a weakened immune system or an underlying health condition, check with your doctor first, as there's a rare theoretical concern with live probiotics in those situations.
What side effects might my child experience?
Most children have no side effects. Occasionally, some experience mild stomach discomfort, bloating, gas, or diarrhea, but these are uncommon. A very small number in trials developed a rash or itching, though it's unclear if these were caused by the probiotic itself.
Does this actually help with diarrhea?
Lactobacillus acidophilus is rated Possibly Effective for antibiotic-associated diarrhea and irritable bowel syndrome. That means there's some evidence it helps, but it's not proven in all cases—results vary.
Is it safe during pregnancy or breastfeeding?
Lactobacillus acidophilus is rated Possibly Safe in pregnancy. We don't have specific data on breastfeeding for this ingredient. Talk with your doctor or midwife before use if you're pregnant or nursing.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if MetaKids Probiotic is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

MetaKids Probiotic label
Go deeper

The Full Monographs Behind MetaKids Probiotic’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lactobacillus Acidophilus

Interacts with 182 drugs

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...

Read the full Lactobacillus Acidophilus monograph →
Sources

Sources & How We Checked

MetaKids Probiotic's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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